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The map label for this gene is pkn1 [H]

Identifier: 218233216

GI number: 218233216

Start: 2700369

End: 2701049

Strand: Reverse

Name: pkn1 [H]

Synonym: BCB4264_A2805

Alternate gene names: 218233216

Gene position: 2701049-2700369 (Counterclockwise)

Preceding gene: 218231402

Following gene: 218232626

Centisome position: 49.84

GC content: 36.27

Gene sequence:

>681_bases
ATGACTAACGATTTAATTCAAACAATCGATTCATTAATGGTAAATATTCCAGTTGGAGAGGTAGTATTAAGAGATGATCG
AATAAAAAAAGAATGGATAGTGCAAATTCAACCATTTCTTCTTGCAAAGTATGCTGTAACAATGGAACTATATGATGCTA
TTACAAATAGTACATTAAATAATTTTGATAAAAATCATAAACCAGTTGTCAATATTTCATGGAACGATGCCATTGCGTTT
TGTAATGTACTTTCAAAAAAAGCGGGAGTAAAAGAATATTATTCTATTAGTGATGGTGGTCAAATTGTGAAATGTAATTT
AGATTCGAATGGCTACCGATTACCATCTGAGGCAGAGTGGCAATATGCATGTAAAGCAAGTACAACCGGATATACATACG
GGAAACTCCATGATATAGCGTGGTATAATGAAAATTCAAATGGAGAGATTCATGAAGTTGGCCAAAAAGAACCGAATGCA
TGGGGGCTTTATGATATGCTAGGGAACGTTTGGGAATGGTGTTATGATTTGTATGATGAAACAGTGTACGGATCATACCG
CATTTTTCGTGGTGGTAGTTGGGCTGAAACAGCGAGAGGATGCGGCGCTACTTGTCGTCGTCGAAGCCATCCTACATTTC
ATATAGATGATCTCGGTTTTAGACTTGCTAGGTCAATTTAG

Upstream 100 bases:

>100_bases
GTTTTTTATTATGAAAAATTTAACGCTTTTTGAAAATTCTATTTTGTAATGAGTATATGACTTTAAGTTCATATAAAATG
AACGTTTGGAGGAATAGAAA

Downstream 100 bases:

>100_bases
TAGGAACATGTTACGAACAGCTAGGAAAAGAGTATGGAGAGAATCCGTACTCTTGCCAACATAGAAACGATTTAACGTAA
GGAGTGTTTATTATGGCGCG

Product: putative cytoplasmic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTNDLIQTIDSLMVNIPVGEVVLRDDRIKKEWIVQIQPFLLAKYAVTMELYDAITNSTLNNFDKNHKPVVNISWNDAIAF
CNVLSKKAGVKEYYSISDGGQIVKCNLDSNGYRLPSEAEWQYACKASTTGYTYGKLHDIAWYNENSNGEIHEVGQKEPNA
WGLYDMLGNVWEWCYDLYDETVYGSYRIFRGGSWAETARGCGATCRRRSHPTFHIDDLGFRLARSI

Sequences:

>Translated_226_residues
MTNDLIQTIDSLMVNIPVGEVVLRDDRIKKEWIVQIQPFLLAKYAVTMELYDAITNSTLNNFDKNHKPVVNISWNDAIAF
CNVLSKKAGVKEYYSISDGGQIVKCNLDSNGYRLPSEAEWQYACKASTTGYTYGKLHDIAWYNENSNGEIHEVGQKEPNA
WGLYDMLGNVWEWCYDLYDETVYGSYRIFRGGSWAETARGCGATCRRRSHPTFHIDDLGFRLARSI
>Mature_225_residues
TNDLIQTIDSLMVNIPVGEVVLRDDRIKKEWIVQIQPFLLAKYAVTMELYDAITNSTLNNFDKNHKPVVNISWNDAIAFC
NVLSKKAGVKEYYSISDGGQIVKCNLDSNGYRLPSEAEWQYACKASTTGYTYGKLHDIAWYNENSNGEIHEVGQKEPNAW
GLYDMLGNVWEWCYDLYDETVYGSYRIFRGGSWAETARGCGATCRRRSHPTFHIDDLGFRLARSI

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth [H]

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI194248087, Length=176, Percent_Identity=30.6818181818182, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI194248088, Length=176, Percent_Identity=30.6818181818182, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI226437577, Length=176, Percent_Identity=30.6818181818182, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 25820; Mature: 25689

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDLIQTIDSLMVNIPVGEVVLRDDRIKKEWIVQIQPFLLAKYAVTMELYDAITNSTLN
CCHHHHHHHHHHEEECCCCCEEECCCCCCHHHHEEECHHHHHHHHHHHHHHHHHHHHHHH
NFDKNHKPVVNISWNDAIAFCNVLSKKAGVKEYYSISDGGQIVKCNLDSNGYRLPSEAEW
HCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHEEECCCCEEEEEEECCCCCCCCCCCCC
QYACKASTTGYTYGKLHDIAWYNENSNGEIHEVGQKEPNAWGLYDMLGNVWEWCYDLYDE
EEEEECCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
TVYGSYRIFRGGSWAETARGCGATCRRRSHPTFHIDDLGFRLARSI
HHCCCEEEEECCCHHHHHHCCCHHHHHCCCCCEEEHHHHHHHHHCC
>Mature Secondary Structure 
TNDLIQTIDSLMVNIPVGEVVLRDDRIKKEWIVQIQPFLLAKYAVTMELYDAITNSTLN
CHHHHHHHHHHEEECCCCCEEECCCCCCHHHHEEECHHHHHHHHHHHHHHHHHHHHHHH
NFDKNHKPVVNISWNDAIAFCNVLSKKAGVKEYYSISDGGQIVKCNLDSNGYRLPSEAEW
HCCCCCCCEEEEECCHHHHHHHHHHHHCCCHHHEEECCCCEEEEEEECCCCCCCCCCCCC
QYACKASTTGYTYGKLHDIAWYNENSNGEIHEVGQKEPNAWGLYDMLGNVWEWCYDLYDE
EEEEECCCCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
TVYGSYRIFRGGSWAETARGCGATCRRRSHPTFHIDDLGFRLARSI
HHCCCEEEEECCCHHHHHHCCCHHHHHCCCCCEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]