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The map label for this gene is fhuG [H]

Identifier: 218233014

GI number: 218233014

Start: 3353478

End: 3354494

Strand: Reverse

Name: fhuG [H]

Synonym: BCB4264_A3473

Alternate gene names: 218233014

Gene position: 3354494-3353478 (Counterclockwise)

Preceding gene: 218231025

Following gene: 218232581

Centisome position: 61.9

GC content: 38.15

Gene sequence:

>1017_bases
GTGAAAGATCTTTTTAACACGGATAAAAAGAGAGCTATTACTGTAACTACAATATTCGGATGTGTAAGTATCGCTGTAAT
TTTAATCAGTCTAAATACAGGGACACTGAGTATAGAGCCACTTAAAGTAATTGAAACACTTTTTGGTTATGGTGATTTTG
AGAGCGCAACCGTGCTATATGATTATCGTATGCCAAGAATTATAATCACAATGTTAGCCGGTATTGGCCTTGGGATTTCC
GGTGCGATTTTGCAAGGATTATCCCGTAATGCACTTGCAGACCCTGGTATTCTTGGACTGCATTCAGGTGCATCTTTCGG
GCTAATTATATTCGTTACATTCTTTCATTCTATTAATGAAAGTGCATCTATTTTAATACCGTTATTTACATTTGGCGGAG
GAGTATTAGCTGCATTTCTTATTATTTTACTTGCGAGTGATCGGTCAAATGGTTTACTTCCCATTAGACTTATTCTCGTT
GGTATTGCAGTTTCAGCTGGTTTTAGTGCAATTTCGTTATTTTTCTCTCTCAAGTTAAATGATGAGACGTATACATTCGC
TTCTAGATGGCTAGTTGGTAACGTGTGGGGAAGGGATTGGATTCATGTCCTTGCATTATTACCTTGGATTTTCATACTAA
CCCCTTATGCGTGGCTAAAATCTAAAACGTTAAATGCATTGTCACTAGGTGATAGTGTAGCGGCAGGACTTGGTGTTTCT
GTTCAAAAAGAACGGTTATTACTTTTAGCTACAGCGGTTGGATTATCTTGCGCAAGTGTATCGATGGCAGGAGGGATTGG
TTTTATCGGTTTAGTTGCTCCGCATATCGCAAGGAAGTTAGTAGGTACTACATATCAACACTTTCTTCCTTTAGCTGGCA
TTATCGGAATGATTATTTTAGTGCTAGCAGATACGATAGGTCGTTCTATATTTGAGCCAAACTCTATTCCAGCTGGTGTA
GTAGTGGCGGCATTAGGAGCACCGTATTTTCTTTATTTACTTACAAAAACAAAATAA

Upstream 100 bases:

>100_bases
AGTAAATCCTCCTAAGGAACTTGCGATAGGGATTATGGTAGCTCTTGTTGGAGTTCCGTTCTTCCTCTATATAGCACGTA
AAGTTGGGAGGGAGTTATAA

Downstream 100 bases:

>100_bases
ATACTTCAAAGAGGAGAACATATGAAAAAGAAACTTACTATTTTATTTAGCATGATGTGTATTTTAGTATTAGCAGCATG
TGGTCAAACGAAAGCTAATG

Product: iron compound ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKDLFNTDKKRAITVTTIFGCVSIAVILISLNTGTLSIEPLKVIETLFGYGDFESATVLYDYRMPRIIITMLAGIGLGIS
GAILQGLSRNALADPGILGLHSGASFGLIIFVTFFHSINESASILIPLFTFGGGVLAAFLIILLASDRSNGLLPIRLILV
GIAVSAGFSAISLFFSLKLNDETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
VQKERLLLLATAVGLSCASVSMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIILVLADTIGRSIFEPNSIPAGV
VVAALGAPYFLYLLTKTK

Sequences:

>Translated_338_residues
MKDLFNTDKKRAITVTTIFGCVSIAVILISLNTGTLSIEPLKVIETLFGYGDFESATVLYDYRMPRIIITMLAGIGLGIS
GAILQGLSRNALADPGILGLHSGASFGLIIFVTFFHSINESASILIPLFTFGGGVLAAFLIILLASDRSNGLLPIRLILV
GIAVSAGFSAISLFFSLKLNDETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
VQKERLLLLATAVGLSCASVSMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIILVLADTIGRSIFEPNSIPAGV
VVAALGAPYFLYLLTKTK
>Mature_338_residues
MKDLFNTDKKRAITVTTIFGCVSIAVILISLNTGTLSIEPLKVIETLFGYGDFESATVLYDYRMPRIIITMLAGIGLGIS
GAILQGLSRNALADPGILGLHSGASFGLIIFVTFFHSINESASILIPLFTFGGGVLAAFLIILLASDRSNGLLPIRLILV
GIAVSAGFSAISLFFSLKLNDETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
VQKERLLLLATAVGLSCASVSMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIILVLADTIGRSIFEPNSIPAGV
VVAALGAPYFLYLLTKTK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=311, Percent_Identity=33.7620578778135, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1786804, Length=306, Percent_Identity=35.6209150326797, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786805, Length=311, Percent_Identity=34.4051446945338, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=31.5972222222222, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788004, Length=307, Percent_Identity=34.2019543973941, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1790741, Length=300, Percent_Identity=32.3333333333333, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35900; Mature: 35900

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLFNTDKKRAITVTTIFGCVSIAVILISLNTGTLSIEPLKVIETLFGYGDFESATVLY
CCCCCCCCCCCEEEHHHHHHHHHHHHHHEEECCCEEEECHHHHHHHHHCCCCCCCEEEEE
DYRMPRIIITMLAGIGLGISGAILQGLSRNALADPGILGLHSGASFGLIIFVTFFHSINE
ECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCC
SASILIPLFTFGGGVLAAFLIILLASDRSNGLLPIRLILVGIAVSAGFSAISLFFSLKLN
CCEEEEEHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEEEC
DETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
CCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCHHHHCCCCC
VQKERLLLLATAVGLSCASVSMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIIL
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLADTIGRSIFEPNSIPAGVVVAALGAPYFLYLLTKTK
HHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCC
>Mature Secondary Structure
MKDLFNTDKKRAITVTTIFGCVSIAVILISLNTGTLSIEPLKVIETLFGYGDFESATVLY
CCCCCCCCCCCEEEHHHHHHHHHHHHHHEEECCCEEEECHHHHHHHHHCCCCCCCEEEEE
DYRMPRIIITMLAGIGLGISGAILQGLSRNALADPGILGLHSGASFGLIIFVTFFHSINE
ECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCC
SASILIPLFTFGGGVLAAFLIILLASDRSNGLLPIRLILVGIAVSAGFSAISLFFSLKLN
CCEEEEEHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEEEEC
DETYTFASRWLVGNVWGRDWIHVLALLPWIFILTPYAWLKSKTLNALSLGDSVAAGLGVS
CCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCHHHHCCCCC
VQKERLLLLATAVGLSCASVSMAGGIGFIGLVAPHIARKLVGTTYQHFLPLAGIIGMIIL
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLADTIGRSIFEPNSIPAGVVVAALGAPYFLYLLTKTK
HHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]