Click here to switch to the map view.

The map label for this gene is gcp [H]

Identifier: 218232539

GI number: 218232539

Start: 251495

End: 252511

Strand: Direct

Name: gcp [H]

Synonym: BCB4264_A0292

Alternate gene names: 218232539

Gene position: 251495-252511 (Clockwise)

Preceding gene: 218233469

Following gene: 218233832

Centisome position: 4.64

GC content: 39.33

Gene sequence:

>1017_bases
ATGGAAAAAAATACGATTATACTTGGTATTGAAACAAGTTGTGATGAAACAGCAGTAGCAGTTGTTAAAAATGGAACGGA
AATTATTGCGAATGTCGTTGCATCACAAATTGAAAGTCATAAACGTTTTGGCGGCGTTGTACCAGAGATTGCATCACGTC
ATCATGTAGAAGAAATTACAGTTGTGTTAGAAGAAGCTTTAAAGGAAGCAAACATCACATTTGATGATATTGATGCAATT
GCTGTAACAGAAGGTCCTGGTTTAGTAGGAGCACTTCTAATTGGAGTAAATGCAGCGAAGGCAGTAGCGTTTGCACATGA
TATTCCGTTAGTCGGTGTTCATCATATTGCTGGTCATATTTATGCGAACCGTTTAGTAAAAGAAGTTCAATTCCCGTTAT
TATCACTTGTTGTATCTGGTGGGCATACAGAACTTGTTTATATGAAAGAACATGGTTCATTTGAAGTAATTGGTGAAACA
CGAGACGATGCAGCTGGAGAAGCATATGATAAAGTAGCTCGTACGTTATCTATGCCATATCCAGGTGGTCCTCATATTGA
TCGCCTTGCACATGAAGGAGAACCGACAATTGATTTGCCTCGTGCATGGCTAGAACCGGATTCGTATGATTTTAGCTTTA
GTGGATTGAAATCAGCAGTTATCAACACTGTGCATAACGCAAAACAGCGCGGTATAGAAATTGCACCAGAAGATTTAGCG
GCAAGTTTCCAAGAAAGTGTAATAGATGTACTTGTAACGAAAGCAGCTCGTGCAGCAGAAGCTTATAATGTAAAGCAATT
ACTTCTTGCTGGTGGAGTAGCTGCTAATAAAGGACTTCGTGCGCGATTAGAAGAGGAATTTGCACAAAAAGAAAACATTG
AATTAATTATTCCGCCGCTATCTTTATGCACAGATAATGCAGCGATGATTGCAGCGGCAGGGACAATTGCTTATGAACAA
GGTAAGCGTGCAACATTAGCCTTAAATGCAAATCCAGGATTAGATATTGAAGCATAG

Upstream 100 bases:

>100_bases
AGCAGTTATACAGAAAATACGGATTTCAAAATGGTGGGATTCGTAAACGATACTATGCAGACAATCAGGAAGATGGTCTC
GTAATGTGGGTGAATATATA

Downstream 100 bases:

>100_bases
TTATACACATAATTAACCACAGGTTGTGGATAAAACCCATATTATCTGTTGATAATGTGGGTTTTATTGTGTATATAAAA
TGTTGATAACTTTTTTATTG

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAI
AVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGET
RDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
ASFQESVIDVLVTKAARAAEAYNVKQLLLAGGVAANKGLRARLEEEFAQKENIELIIPPLSLCTDNAAMIAAAGTIAYEQ
GKRATLALNANPGLDIEA

Sequences:

>Translated_338_residues
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAI
AVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGET
RDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
ASFQESVIDVLVTKAARAAEAYNVKQLLLAGGVAANKGLRARLEEEFAQKENIELIIPPLSLCTDNAAMIAAAGTIAYEQ
GKRATLALNANPGLDIEA
>Mature_338_residues
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEITVVLEEALKEANITFDDIDAI
AVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHIYANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGET
RDDAAGEAYDKVARTLSMPYPGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
ASFQESVIDVLVTKAARAAEAYNVKQLLLAGGVAANKGLRARLEEEFAQKENIELIIPPLSLCTDNAAMIAAAGTIAYEQ
GKRATLALNANPGLDIEA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI8923380, Length=328, Percent_Identity=36.5853658536585, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI116812636, Length=333, Percent_Identity=33.6336336336336, Blast_Score=164, Evalue=8e-41,
Organism=Escherichia coli, GI1789445, Length=328, Percent_Identity=43.5975609756098, Blast_Score=279, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=32.3076923076923, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=326, Percent_Identity=32.2085889570552, Blast_Score=145, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320099, Length=351, Percent_Identity=33.048433048433, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6322891, Length=351, Percent_Identity=30.4843304843305, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI20129063, Length=361, Percent_Identity=31.8559556786704, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21357207, Length=329, Percent_Identity=31.306990881459, Blast_Score=151, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36028; Mature: 36028

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEIT
CCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHI
HHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
YANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCC
PGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
CCCCCHHHHHCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHH
ASFQESVIDVLVTKAARAAEAYNVKQLLLAGGVAANKGLRARLEEEFAQKENIELIIPPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCH
SLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
HHHCCCCEEEEEECHHEECCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MEKNTIILGIETSCDETAVAVVKNGTEIIANVVASQIESHKRFGGVVPEIASRHHVEEIT
CCCCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVLEEALKEANITFDDIDAIAVTEGPGLVGALLIGVNAAKAVAFAHDIPLVGVHHIAGHI
HHHHHHHHHCCCCHHCCCEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
YANRLVKEVQFPLLSLVVSGGHTELVYMKEHGSFEVIGETRDDAAGEAYDKVARTLSMPY
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCCC
PGGPHIDRLAHEGEPTIDLPRAWLEPDSYDFSFSGLKSAVINTVHNAKQRGIEIAPEDLA
CCCCCHHHHHCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEECHHHHH
ASFQESVIDVLVTKAARAAEAYNVKQLLLAGGVAANKGLRARLEEEFAQKENIELIIPPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEECCH
SLCTDNAAMIAAAGTIAYEQGKRATLALNANPGLDIEA
HHHCCCCEEEEEECHHEECCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA