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The map label for this gene is adP2 [C]

Identifier: 218232536

GI number: 218232536

Start: 2909261

End: 2910427

Strand: Reverse

Name: adP2 [C]

Synonym: BCB4264_A3030

Alternate gene names: 218232536

Gene position: 2910427-2909261 (Counterclockwise)

Preceding gene: 218234624

Following gene: 218233799

Centisome position: 53.71

GC content: 38.73

Gene sequence:

>1167_bases
ATGAAAAAATGTAATTCAATTAAGTTAGCAAGTTTTGCAGTTTTATTAGCGGGTACTGCTCTATTCACACCTGGTTTTAC
TGTGACTGCAGAGTCAACCCAAAATATTTCTAGTTCGTCACAAGTACATGATCAAAAGAATCGTAATGGCTGGAAACAAG
TAATGCAGGAAACAGTACAGCTTGGTGCTGTAGGAATATTAGCTAAGGCGTCTAATAACGGAAAAACTAATAGTTTTACT
GCAGGCGTGGCGGACTTAAGTACAAAGAAACCGGTGAATTCGGATTATCGCTTTCGGATTGGTAGTGTGACGAAGACGTT
TACTGCCACGACTATTCTTCAATTAGTAGGAGAAAATCGCTTACAACTTGACGATCCAATTGAAAAGTGGCTACCGGGTC
TCGTGCAAGGAAATGGGTATGATGGTAATCAAATTACGATACGACAACTTTTGAATCATACGAGTGGTATCGCTGAATAC
TTAAAGTCAAAAGACGCGGACATAATGAATTCGAAAAAAACGTATACAGCAGAAGAAATAGTGAAAATAGGTCTTTCGCT
GCCTCCAGATTTTTCGCCGGGAAAAGACTGGTTGTATTCAAACACAGGATACGTAATACTAGGAATGCTTATTGAAAAAA
TAACTGGAAATAGTTATGCGGAAGAAATCGAAAAGCGAATTATTGAACCTTTGGACCTATCAAATACGTTTTTACCAGGA
AATTCACCCGTCATCCCAGGAAAGAATCATGCTCGTGGATATGTGAAAATGGAAGGAACAGGCGAGTTGAAAGATATTAC
GTATTATAATCCAAGTTTAGCTAATGCAGCTGGAGATATGATTTCTAATGCGGATGATTTAAATAAGTTCTTTTCATCTT
TACTCGGTGGTAAGTTACTGAAGGAACGCGAGCTAAAAGAAATGCTTACTACAGTTCCTATAGAAGGAAAAGGGGTTGGT
GACGCATACGGTCTTGGAATCTATGAGACTAAACTTCCAAACGGTGTTTCAGTTTGGGGGCATGGAGGAGGAATTCCTGG
ATTTACAACTTTTGCTGGGGGAGTAATTGGAGGCAAACATACATTGGCTATCAGTCTCAACTCTATAGGTGGGGTCGATA
TTGTTCCGCAGTTTAATAAAATGATGCAAATTGAATTTAATAAATAG

Upstream 100 bases:

>100_bases
AGTATTTCGTAAGGAATGGATAAGAAAAAAGAGAGATTTATCATATAGGATGAAAGTATAGCCTGAATCAATCCGATATT
AATGGAGGAGAGAAAGCCTT

Downstream 100 bases:

>100_bases
ATGAAAAGAAAGTGAATGGAATTTTGTTATAGTTATATTTAAAAGAGGTGCTTTTTTAAGTTCGCAACTATGGACAGTAG
TTGCATTTATGATATGGCAT

Product: alkaline D-peptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKKCNSIKLASFAVLLAGTALFTPGFTVTAESTQNISSSSQVHDQKNRNGWKQVMQETVQLGAVGILAKASNNGKTNSFT
AGVADLSTKKPVNSDYRFRIGSVTKTFTATTILQLVGENRLQLDDPIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLSNTFLPG
NSPVIPGKNHARGYVKMEGTGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPIEGKGVG
DAYGLGIYETKLPNGVSVWGHGGGIPGFTTFAGGVIGGKHTLAISLNSIGGVDIVPQFNKMMQIEFNK

Sequences:

>Translated_388_residues
MKKCNSIKLASFAVLLAGTALFTPGFTVTAESTQNISSSSQVHDQKNRNGWKQVMQETVQLGAVGILAKASNNGKTNSFT
AGVADLSTKKPVNSDYRFRIGSVTKTFTATTILQLVGENRLQLDDPIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLSNTFLPG
NSPVIPGKNHARGYVKMEGTGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPIEGKGVG
DAYGLGIYETKLPNGVSVWGHGGGIPGFTTFAGGVIGGKHTLAISLNSIGGVDIVPQFNKMMQIEFNK
>Mature_388_residues
MKKCNSIKLASFAVLLAGTALFTPGFTVTAESTQNISSSSQVHDQKNRNGWKQVMQETVQLGAVGILAKASNNGKTNSFT
AGVADLSTKKPVNSDYRFRIGSVTKTFTATTILQLVGENRLQLDDPIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLSNTFLPG
NSPVIPGKNHARGYVKMEGTGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPIEGKGVG
DAYGLGIYETKLPNGVSVWGHGGGIPGFTTFAGGVIGGKHTLAISLNSIGGVDIVPQFNKMMQIEFNK

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=299, Percent_Identity=26.4214046822742, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI87082101, Length=148, Percent_Identity=29.0540540540541, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17550934, Length=277, Percent_Identity=29.6028880866426, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI115533026, Length=320, Percent_Identity=25.9375, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17565630, Length=286, Percent_Identity=26.9230769230769, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 41864; Mature: 41864

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKCNSIKLASFAVLLAGTALFTPGFTVTAESTQNISSSSQVHDQKNRNGWKQVMQETVQ
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
LGAVGILAKASNNGKTNSFTAGVADLSTKKPVNSDYRFRIGSVTKTFTATTILQLVGENR
HHHHEEEEECCCCCCCCCEECCHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCC
LQLDDPIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEYLKSKDADIMNSKKTYTAEEI
CCCCCCHHHHCCHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHH
VKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLSNTFLPG
HHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
NSPVIPGKNHARGYVKMEGTGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLL
CCCCCCCCCCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCHHHH
KERELKEMLTTVPIEGKGVGDAYGLGIYETKLPNGVSVWGHGGGIPGFTTFAGGVIGGKH
HHHHHHHHHHHCCCCCCCCCCHHCCCEEEECCCCCCEECCCCCCCCCHHHHHCCCCCCCE
TLAISLNSIGGVDIVPQFNKMMQIEFNK
EEEEEECCCCCEEECCCCCCEEEEEECC
>Mature Secondary Structure
MKKCNSIKLASFAVLLAGTALFTPGFTVTAESTQNISSSSQVHDQKNRNGWKQVMQETVQ
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHH
LGAVGILAKASNNGKTNSFTAGVADLSTKKPVNSDYRFRIGSVTKTFTATTILQLVGENR
HHHHEEEEECCCCCCCCCEECCHHHCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCC
LQLDDPIEKWLPGLVQGNGYDGNQITIRQLLNHTSGIAEYLKSKDADIMNSKKTYTAEEI
CCCCCCHHHHCCHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHH
VKIGLSLPPDFSPGKDWLYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLSNTFLPG
HHHCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
NSPVIPGKNHARGYVKMEGTGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLL
CCCCCCCCCCCCEEEEECCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCHHHH
KERELKEMLTTVPIEGKGVGDAYGLGIYETKLPNGVSVWGHGGGIPGFTTFAGGVIGGKH
HHHHHHHHHHHCCCCCCCCCCHHCCCEEEECCCCCCEECCCCCCCCCHHHHHCCCCCCCE
TLAISLNSIGGVDIVPQFNKMMQIEFNK
EEEEEECCCCCEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]