Click here to switch to the map view.

The map label for this gene is tcyB [H]

Identifier: 218232526

GI number: 218232526

Start: 875191

End: 875820

Strand: Direct

Name: tcyB [H]

Synonym: BCB4264_A0909

Alternate gene names: 218232526

Gene position: 875191-875820 (Clockwise)

Preceding gene: 218234702

Following gene: 218232147

Centisome position: 16.15

GC content: 36.51

Gene sequence:

>630_bases
ATGCCTATGCTGAAGGAAGCTGTTTTTACAACAATTCCATTAACGCTTATTACATTTATTATCGGTCTTATACTTGCGAC
GTTAACAGCGCTCGCACGTATTTCAGGTAGTCGTATTTTACAATGGATTGCTCGTATCTATGTATCTATCATTCGCGGAA
CGCCACTTCTTGTACAGTTATTTATTATTTTCTATGGTCTTCCAACTCTTAATATTGAAGTTGAGCCATATACAGCAGCA
GTTGTTGGATTTTCATTAAATGTCGGTGCATATGCATCTGAAATTATTCGTGCTTCTATCCTTTCCATTCCGAAAGGGCA
GTGGGAAGCAGCTTATACAATTGGGATGACATATCCACAAGCATTAAAACGTGTTATTTTACCACAAGCAACACGCGTAT
CAATCCCGCCGCTTTCGAATACATTTATTAGCTTAGTGAAGGATACTTCATTAGCATCGTTAATTTTAGTAACAGAAATG
TTCCGAAAAGCGCAGGAAATTGCGGCGATGAACTACGAGTTTTTAATTGTTTATTTTGAAGCAGGTCTTATTTATTGGGT
TATTTGTTTCTTATTATCAATCGTACAACAGATGTTAGAAAAGCGTTCAGAACGCTACACATTAAAATAA

Upstream 100 bases:

>100_bases
GACAAAATAACGAAAAAATGGTTCGGTGAAAATGTATCTAAGTAGTGCATTAGTTTCAGATCGATTGTCTACTTGGATAG
ATATTATGCAGACTTCCTTC

Downstream 100 bases:

>100_bases
TCCTTTTACAAAAGGAGTTTTTGTTTTTATGATTTCAATTCAGCACTTACAAAAAAGTTTCGGAGATAATACCGTACTAA
AGCATATAGATTTAACAGTT

Product: amino acid ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MPMLKEAVFTTIPLTLITFIIGLILATLTALARISGSRILQWIARIYVSIIRGTPLLVQLFIIFYGLPTLNIEVEPYTAA
VVGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSIPPLSNTFISLVKDTSLASLILVTEM
FRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK

Sequences:

>Translated_209_residues
MPMLKEAVFTTIPLTLITFIIGLILATLTALARISGSRILQWIARIYVSIIRGTPLLVQLFIIFYGLPTLNIEVEPYTAA
VVGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSIPPLSNTFISLVKDTSLASLILVTEM
FRKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK
>Mature_208_residues
PMLKEAVFTTIPLTLITFIIGLILATLTALARISGSRILQWIARIYVSIIRGTPLLVQLFIIFYGLPTLNIEVEPYTAAV
VGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQALKRVILPQATRVSIPPLSNTFISLVKDTSLASLILVTEMF
RKAQEIAAMNYEFLIVYFEAGLIYWVICFLLSIVQQMLEKRSERYTLK

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=205, Percent_Identity=50.2439024390244, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=37.2549019607843, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787086, Length=213, Percent_Identity=32.3943661971831, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786873, Length=211, Percent_Identity=33.6492890995261, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1787087, Length=227, Percent_Identity=28.6343612334802, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI87082239, Length=200, Percent_Identity=37.5, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788645, Length=208, Percent_Identity=30.7692307692308, Blast_Score=98, Evalue=3e-22,
Organism=Escherichia coli, GI1788646, Length=208, Percent_Identity=27.8846153846154, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1786874, Length=170, Percent_Identity=31.1764705882353, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI48994930, Length=122, Percent_Identity=36.0655737704918, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23443; Mature: 23312

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMLKEAVFTTIPLTLITFIIGLILATLTALARISGSRILQWIARIYVSIIRGTPLLVQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FIIFYGLPTLNIEVEPYTAAVVGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQ
HHHHHCCCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHH
ALKRVILPQATRVSIPPLSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFE
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHH
AGLIYWVICFLLSIVQQMLEKRSERYTLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PMLKEAVFTTIPLTLITFIIGLILATLTALARISGSRILQWIARIYVSIIRGTPLLVQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FIIFYGLPTLNIEVEPYTAAVVGFSLNVGAYASEIIRASILSIPKGQWEAAYTIGMTYPQ
HHHHHCCCCEEEEECCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHH
ALKRVILPQATRVSIPPLSNTFISLVKDTSLASLILVTEMFRKAQEIAAMNYEFLIVYFE
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHH
AGLIYWVICFLLSIVQQMLEKRSERYTLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]