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The map label for this gene is argF1 [H]

Identifier: 218232375

GI number: 218232375

Start: 397998

End: 398996

Strand: Direct

Name: argF1 [H]

Synonym: BCB4264_A0421

Alternate gene names: 218232375

Gene position: 397998-398996 (Clockwise)

Preceding gene: 218232964

Following gene: 218231726

Centisome position: 7.34

GC content: 34.53

Gene sequence:

>999_bases
ATGTTAATGACTAGACCAAATTTAAAAGGAAGAAGCTTTCTAGCAGAAAAAGATTTTACACAAGAAGAATTGTTATATTT
TCTAGATTTGGCAGCAGAATTAAAAGAGAAAAAGAAAAATGGTATCCCGCATCATTATTTAGAAGGTAAAAATGTAGCGC
TCTTATTTGAAAAAACTTCTACTCGTACGCGTTGTGCATTTACAGTAGCATGTACAGATTTAGGAGCAAATCCTGAATAT
TTAGGGAAAGGTGATATTCAACTTGGGAAAAAAGAATCTGTAGAGGATACAGCAAAAGTGTTAGGGCGTATGTTTGACGG
AATTGAGTTTCGTGGATTTAATCATGAAACTGTAGAATCTTTAGCACAAAATTCTGGTGTGCCAGTTTGGAATGGATTAA
CAGATATGTGGCATCCAACACAAACACTAGCAGATTTATTAACAATTAGAGAACATATAGGGAAATTGAAAAATGTGAAG
CTCGTTTACGTTGGCGATGGGCGAAATAATGTTGCTAATAGCTTACTAGTTGGTGGAGCAATCGTTGGAATGGATGTACG
TATTTGTACACCGGAATCTTTATGGCCTGCACAAGAAGTAATTGATTTAGCAAAAAAATATAATGAACAAGTAATGATAA
CAAGTAATGTGGAAGAAGCTGTTGCAAGTGCAGATGTAATTTATACAGATGTATGGGTGTCTATGGGGGAAGAAGAAAAA
TTTGCTGAACGTGTCGAGTTATTGAAACCTTATCAAGTAAATATGAAAATGATTAAAGCAACAGGGAATGAAAACGTAAT
TTTCTTACATTGTTTACCTGCATTTCATGATGTTGAAACGATGTATGGCGAAGAAGTTTATGAGAAATATGGGTTGAAAG
AAATGGAGGTAACTGACGAAGTATTCCGCAGTAAACATTCAAAAGTATTTGATCAAGCTGAAAATAGAATGCATACAATT
AAAGCGGTTATGGCAGCTACTTTAGGAAACATGGAGTAA

Upstream 100 bases:

>100_bases
TTCGGAATTATCTCGTGGTCGTGGGGGTCCACGTTGCATGAGTATGCCAATTGTTCGTAAAGATATTTAGTATAAATAAC
GGAGAAAGTAGGGATGAATT

Downstream 100 bases:

>100_bases
AGAAGAAAGGGAGTCTTCCTTTCTTCTTTCTCCTCCTTTAGACACGATCATTCACTATTGCTTTTGTATTGTTATTGCAA
TTTAAGAGAGGTGAGTGGAA

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHIGKLKNVK
LVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
FAERVELLKPYQVNMKMIKATGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI
KAVMAATLGNME

Sequences:

>Translated_332_residues
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHIGKLKNVK
LVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
FAERVELLKPYQVNMKMIKATGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI
KAVMAATLGNME
>Mature_332_residues
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEY
LGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHIGKLKNVK
LVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
FAERVELLKPYQVNMKMIKATGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTI
KAVMAATLGNME

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=332, Percent_Identity=39.1566265060241, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI18105007, Length=336, Percent_Identity=24.702380952381, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786469, Length=331, Percent_Identity=55.2870090634441, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=56.1349693251534, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI48994908, Length=370, Percent_Identity=26.7567567567568, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI2367364, Length=342, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193204318, Length=260, Percent_Identity=28.0769230769231, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=337, Percent_Identity=34.4213649851632, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6322331, Length=281, Percent_Identity=25.2669039145907, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24642586, Length=328, Percent_Identity=25.609756097561, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37435; Mature: 37435

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCC
TRTRCAFTVACTDLGANPEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVES
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHHHH
LAQNSGVPVWNGLTDMWHPTQTLADLLTIREHIGKLKNVKLVYVGDGRNNVANSLLVGGA
HHHCCCCCEECCCHHHCCCHHHHHHHHHHHHHHCHHHCEEEEEEECCCCHHHHHHHHCCE
IVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
EEECEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHEEEHHHHHCCCHHH
FAERVELLKPYQVNMKMIKATGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDE
HHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
VFRSKHSKVFDQAENRMHTIKAVMAATLGNME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCC
TRTRCAFTVACTDLGANPEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVES
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCHHHHHH
LAQNSGVPVWNGLTDMWHPTQTLADLLTIREHIGKLKNVKLVYVGDGRNNVANSLLVGGA
HHHCCCCCEECCCHHHCCCHHHHHHHHHHHHHHCHHHCEEEEEEECCCCHHHHHHHHCCE
IVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVASADVIYTDVWVSMGEEEK
EEECEEEEECCCCCCCHHHHHHHHHHCCCEEEEECCHHHHHHHHHHEEEHHHHHCCCHHH
FAERVELLKPYQVNMKMIKATGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDE
HHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHH
VFRSKHSKVFDQAENRMHTIKAVMAATLGNME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA