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The map label for this gene is ftsK [H]

Identifier: 218232354

GI number: 218232354

Start: 3810340

End: 3812721

Strand: Reverse

Name: ftsK [H]

Synonym: BCB4264_A3893

Alternate gene names: 218232354

Gene position: 3812721-3810340 (Counterclockwise)

Preceding gene: 218234123

Following gene: 218231423

Centisome position: 70.36

GC content: 37.74

Gene sequence:

>2382_bases
ATGGCAAAACAAAAGCAAAGAGGGACGAAGGCAAAGGCAAGACGTACGATAAAGCCAACTTTGTATTATGAAATCGTCGG
TTTAACTCTTTTTGCACTTTCAATCATTACGATTTTACAGCTAGGCGTTGTAGGGAAATCGTTTGTGTTATTTTTTCGCT
TCTTCTTTGGTGAGTGGTACATAATTGGTGTGTTAGGTGTAATAGCTTTATCGGTTTCCTTTGTTATAAAACGCGGATGG
CCGAACCTTTTAAATAAACGATTAATTGGATTTTATTTAATTGTATTGGCGATATTAATGTTTAGTCATATTACATTATT
TAACCTTCTTACAAAAGATGGAGCAGTGCAAAATACTTCTGTTATTGTGAGTACGAAAGATAACTTCTTTCTTGAAATGA
AAAAGGGGCCAGATAGCGTTCATTTAGGTGGTGGTATGTTTGGTGCGCTTATGTTCGCAACATGTTACTTCTTATTTGAC
GAAGTAGGAGCTTATATCATTGGTATTATTCTAGTTATTCTCGGTATACTTTGTATAACAAATAAGCATATTGGAGAAGT
GTTAGCTCCAGTTGGTAGAATTCTTAGAAGTCAGTTTCAAGTGATGCAAGGGGATTATAAAGATTGGAGAGCCAAAAGAA
CGGCTGAACAAACAGAAAAGAAAAAAACAACAAGAAGCACAAGAAGCAAACGTGCTGCAGAACAAGAAGAAATTATTGAG
CCGATGGAAGAAATCTCAATTGATCCTCCGATTATTTCGAATTTCACTGAGAATTATCCTGTAAATGAAGAAGAGGATAA
ACGAATTGAAGTAGAGCAAGAAGAGTTGATCACTTCACCGTTTATTGAAGAGACTCCGCCAATTGAAGAACCAAAGAAAA
AGCGTGGAGAAAAAATTGTTGAATCGTTAGAGAGCGAAGCGCAAGCACCTCCTATGCAATTTTCAAATGTAGAAAATAAA
GATTACAAGCTTCCTTCACTTGATATATTAAAATTTCCAAAGAATAAGCAAGTTACAAATGAAAATGCGGAAATTTATGA
GAATGCTCGTAAATTAGAACGTACATTCCAAAGTTTTGGAGTGAAAGCGAAAGTAACAAAAGTGCATAGAGGTCCTGCAG
TTACAAAATATGAAGTGTATCCTGATATGGGGGTAAAGGTAAGCAAAATTGTCAGTTTAAGTGATGATTTAGCCCTTGCT
TTAGCTGCAAAGGACATTCGTATTGAAGCGCCAATTCCCGGGAAATCAGCTGTAGGGATCGAAGTTCCAAACTCAGAGGT
TTCGATGGTAACGCTGAGGGAAGTTCTTGACTCCAAGGCTAATAATCATCCGGAAGAGAAGTTGTTAATTGGTCTTGGCC
GAGATATTACAGGTGAAGCTGTATTAGCCCGTCTAAATAAAATGCCTCATTTACTCGTAGCTGGTGCGACAGGTAGCGGG
AAAAGTGTATGTATTAACGGTATTATTGTTAGTATTTTAATGCGTGCAAAACCACATGAAGTAAAATTAATGATGATTGA
CCCGAAAATGGTAGAGCTAAATGTATATAACGGTGTGCCTCATTTGTTAACGCCAGTTGTAACTGATCCGAAAAAAGCAT
CGCAAGCATTGAAAAAAGTTGTGAGTGAAATGGAACGTCGTTATGAATTGTTTGCTCATAGTGGTACACGTAACATTGAA
GGATACAACGATTATATAAAAGAGCATAATAGTCAATCAGAAGCGAAACAACCCGAATTACCTTATATTGTAGTAATTGT
GGACGAGTTAGCAGATTTAATGATGGTTGCTTCGTCTGATGTAGAGGATGCGATTATGCGTCTAGCGCAAATGGCTCGTG
CTGCTGGTATTCATTTAATTATTGCAACGCAACGTCCGTCAGTTGACGTTATTACGGGTGTTATTAAAGCAAATATTCCA
TCACGTATTGCATTCGCTGTATCTTCTCAAACAGATTCTCGTACAATTCTTGACGGTGGTGGTGCAGAGAAGCTACTAGG
TCGTGGAGACATGCTGTTTATACCAATTGGTGCATCGAAACCTGTACGTGTACAAGGCGCATTTCTATCAGATGATGAAG
TTGAGAGAGTTGTAGAATATGTTATTGGACAGCAAAAAGCACAATATCAAGAAGATATGATTCCGCAAGATGTTCCTGAT
ACGAAGCAGGAAGTAGAAGATGAATTATATGATGAAGCGGTTCAACTTGTAGTGGAAATGCAAACAGCATCTGTTTCTAT
GTTACAACGTAGGTTTAGAGTAGGTTATACGCGAGCTGCTCGCCTAATTGATGCAATGGAAATGAATGGTGTAGTAGGTC
CGTATGAAGGGAGTAAACCGAGGGAAGTACTCATTAATGATGTACAAGAAAAAAGTTCTTAA

Upstream 100 bases:

>100_bases
AAAATAGAAGATATAAAGACCTGAAAAATAGAGAAAACAGACATATAAATAGAGCATTTTGAAGGGAGCTTTACTTATAT
GTAGAACACGAGGTGAAGAA

Downstream 100 bases:

>100_bases
AAAAAGCCTAATTGTTTTTACAATTAGGCTTTTTTATATAGTGTTTTTGTTATATACTATACTCAGCGATAAAGAAAGGG
CTTACATTTAGGGGTGCCCT

Product: stage III sporulation protein E

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 793; Mature: 792

Protein sequence:

>793_residues
MAKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWYIIGVLGVIALSVSFVIKRGW
PNLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTSVIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFD
EVGAYIIGIILVILGILCITNKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRAAEQEEIIE
PMEEISIDPPIISNFTENYPVNEEEDKRIEVEQEELITSPFIEETPPIEEPKKKRGEKIVESLESEAQAPPMQFSNVENK
DYKLPSLDILKFPKNKQVTNENAEIYENARKLERTFQSFGVKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVSLSDDLALA
LAAKDIRIEAPIPGKSAVGIEVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSG
KSVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKVVSEMERRYELFAHSGTRNIE
GYNDYIKEHNSQSEAKQPELPYIVVIVDELADLMMVASSDVEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIP
SRIAFAVSSQTDSRTILDGGGAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPD
TKQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKPREVLINDVQEKSS

Sequences:

>Translated_793_residues
MAKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWYIIGVLGVIALSVSFVIKRGW
PNLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTSVIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFD
EVGAYIIGIILVILGILCITNKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRAAEQEEIIE
PMEEISIDPPIISNFTENYPVNEEEDKRIEVEQEELITSPFIEETPPIEEPKKKRGEKIVESLESEAQAPPMQFSNVENK
DYKLPSLDILKFPKNKQVTNENAEIYENARKLERTFQSFGVKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVSLSDDLALA
LAAKDIRIEAPIPGKSAVGIEVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSG
KSVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKVVSEMERRYELFAHSGTRNIE
GYNDYIKEHNSQSEAKQPELPYIVVIVDELADLMMVASSDVEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIP
SRIAFAVSSQTDSRTILDGGGAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPD
TKQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKPREVLINDVQEKSS
>Mature_792_residues
AKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWYIIGVLGVIALSVSFVIKRGWP
NLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTSVIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFDE
VGAYIIGIILVILGILCITNKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRAAEQEEIIEP
MEEISIDPPIISNFTENYPVNEEEDKRIEVEQEELITSPFIEETPPIEEPKKKRGEKIVESLESEAQAPPMQFSNVENKD
YKLPSLDILKFPKNKQVTNENAEIYENARKLERTFQSFGVKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVSLSDDLALAL
AAKDIRIEAPIPGKSAVGIEVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSGK
SVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKVVSEMERRYELFAHSGTRNIEG
YNDYIKEHNSQSEAKQPELPYIVVIVDELADLMMVASSDVEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPS
RIAFAVSSQTDSRTILDGGGAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPDT
KQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKPREVLINDVQEKSS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=486, Percent_Identity=49.3827160493827, Blast_Score=423, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 88391; Mature: 88260

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWY
CCCCHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGVLGVIALSVSFVIKRGWPNLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFDEVGAYIIGIILVILGILCIT
EEEEECCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRAAEQEEIIE
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PMEEISIDPPIISNFTENYPVNEEEDKRIEVEQEELITSPFIEETPPIEEPKKKRGEKIV
HHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHH
ESLESEAQAPPMQFSNVENKDYKLPSLDILKFPKNKQVTNENAEIYENARKLERTFQSFG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCC
VKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVSLSDDLALALAAKDIRIEAPIPGKSAVGI
CEEEEEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCEEEEEEECEEEECCCCCCCEEEE
EVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSG
ECCCCCHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCC
KSVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKV
CHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCCHHHHCCCCCCHHHHHHHHHHH
VSEMERRYELFAHSGTRNIEGYNDYIKEHNSQSEAKQPELPYIVVIVDELADLMMVASSD
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHCCCCCCCEEEEEHHHHHHHHHHHCCC
VEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGG
HHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCC
GAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPD
CHHHHHCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
TKQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
REVLINDVQEKSS
HHHHHHHHHHCCC
>Mature Secondary Structure 
AKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWY
CCCHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGVLGVIALSVSFVIKRGWPNLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFDEVGAYIIGIILVILGILCIT
EEEEECCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRAAEQEEIIE
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PMEEISIDPPIISNFTENYPVNEEEDKRIEVEQEELITSPFIEETPPIEEPKKKRGEKIV
HHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHH
ESLESEAQAPPMQFSNVENKDYKLPSLDILKFPKNKQVTNENAEIYENARKLERTFQSFG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCC
VKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVSLSDDLALALAAKDIRIEAPIPGKSAVGI
CEEEEEEEECCCCCEEEEECCCCCCCHHHHHHCCCCCEEEEEEECEEEECCCCCCCEEEE
EVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSG
ECCCCCHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCC
KSVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKV
CHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCCHHHHCCCCCCHHHHHHHHHHH
VSEMERRYELFAHSGTRNIEGYNDYIKEHNSQSEAKQPELPYIVVIVDELADLMMVASSD
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHCCCCCCCEEEEEHHHHHHHHHHHCCC
VEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGG
HHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCC
GAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPD
CHHHHHCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
TKQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
REVLINDVQEKSS
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]