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The map label for this gene is yfnA [H]

Identifier: 218232123

GI number: 218232123

Start: 615244

End: 616659

Strand: Direct

Name: yfnA [H]

Synonym: BCB4264_A0631

Alternate gene names: 218232123

Gene position: 615244-616659 (Clockwise)

Preceding gene: 218232919

Following gene: 218234809

Centisome position: 11.35

GC content: 37.78

Gene sequence:

>1416_bases
GTGGCCAACCTATTTAAAAAGAAATCCGTTACGCAATTGTTAGGGGAAAGTAAAAGTAAAACTTTGACGAAAACGCTAGG
GGCATTTGACCTAACAATGCTAGGGATTGGTGCGATAATTGGTACAGGAGTTCTAGTATTAACTGGATTAGTAGCAGCAA
GAGATGCTGGTCCAGCAGTTATTTTTTCATTCATGATTGCAGCCATCGTTTGTGGATTTGCAGCATTATGTTACGCAGAG
GTTGCTTCTACACTTCCTGTTTCAGGTAGTGTGTACACATACTCATATGCAACAATTGGTGAGTTTGTAGCTCATTTAAT
GGGATGGACATTACTATCCGTATATGTTGTAACGACTGCCGCAGTAGCTGGCGGATGGACTGGTTACTTCCATAACTTAG
TGAGTGGATTAGGGCTTGAAATTCCAAAAGCACTGCTAACGATTCCGTCTCAAGGTGGTATAGTGAATTTACCAGCAGTT
ATCGTTACATTAGTTATAACTTGGTTATTATCAAGAGGTACGAAAGAAAGTAAACGAGTGAATAACATAATGGTATTAAT
TAAAATTGGTATCGTTGTTTTATTCATTGCAGTTGGTGTATTCTACGTGAAACCAGAAAACTGGATACCATTTGCACCGT
ACGGTTTAAGTGGAGTTTTCGCGGGGGGAGCAGCAGTATTCTTTGCTTTCTTAGGATTTGATGCATTAGCAACTTCTGCT
GAAGAAGTAAAAAATCCGCAACGTGATCTACCGATTGGTATTATCGCTTCGTTAGTCATTTGTACAATCATTTATGTTGT
AGTTTGTCTCGTTATGACGGGTATGGTTTCATATAAAGAGCTAGATGTACCGGAAGCGATGGCGTATGTGTTAGAAGTTG
TAGGACAAGATAAAGTAGCTGGTATAATCGCAATTGGAGCTGTAATTGGTATTATGGCAGTAATTTTTGCTTACATTTAT
GCAACGACACGTGTATTCTTTGCGATGAGCCGTGACGGTTTATTGCCAGAATCTTTCGCGAAAATTAATAAAAAGACAGA
AGCGCCAACATTTACAGTTTGGTTAACAGGAATTGGTAGTGCTTTAATTGCTGGATTTATCGATTTAAAAGAATTGTCGA
ATTTAGCGAATATTGGAGCGTTGTTAACATTTGCGATGGTTGGTGTGTCAGTTATTATTCTTCGTAAAACACATCCAAAA
TTACAACGTGGATTTATGGTACCACTTGTACCGATCTTACCGATTATTTCGATTGCATGTTGTCTATTCTTAATGGTAAA
TCTACCATTAAAAACATGGATGTACTTCGGTGCTTGGTTAGCAATTGGAGTAGTTGTATACTTTGTTTATTCGAAAAAAC
ATAGTCATTTAAAAGACGATGGAAGTTCGCAGGATAATTTAGAACAAGCTAATTAA

Upstream 100 bases:

>100_bases
AAGCATTATACAAAACAAAATCGAACAATATATAAAACAACATGATAAGAGCTAAGAGTGAAGATCTCTTAGCTCTTCTT
GGCAAAAGGGGGCATACATC

Downstream 100 bases:

>100_bases
AAGCTTAATTAAAAGGGATATAAGTATAGTAAGCCTTGTGCGTCTAGGGAGCGCGCAAGGCTTTTTCTTTTGTTGAAATA
AAGGGAATGTATATTACTTT

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MANLFKKKSVTQLLGESKSKTLTKTLGAFDLTMLGIGAIIGTGVLVLTGLVAARDAGPAVIFSFMIAAIVCGFAALCYAE
VASTLPVSGSVYTYSYATIGEFVAHLMGWTLLSVYVVTTAAVAGGWTGYFHNLVSGLGLEIPKALLTIPSQGGIVNLPAV
IVTLVITWLLSRGTKESKRVNNIMVLIKIGIVVLFIAVGVFYVKPENWIPFAPYGLSGVFAGGAAVFFAFLGFDALATSA
EEVKNPQRDLPIGIIASLVICTIIYVVVCLVMTGMVSYKELDVPEAMAYVLEVVGQDKVAGIIAIGAVIGIMAVIFAYIY
ATTRVFFAMSRDGLLPESFAKINKKTEAPTFTVWLTGIGSALIAGFIDLKELSNLANIGALLTFAMVGVSVIILRKTHPK
LQRGFMVPLVPILPIISIACCLFLMVNLPLKTWMYFGAWLAIGVVVYFVYSKKHSHLKDDGSSQDNLEQAN

Sequences:

>Translated_471_residues
MANLFKKKSVTQLLGESKSKTLTKTLGAFDLTMLGIGAIIGTGVLVLTGLVAARDAGPAVIFSFMIAAIVCGFAALCYAE
VASTLPVSGSVYTYSYATIGEFVAHLMGWTLLSVYVVTTAAVAGGWTGYFHNLVSGLGLEIPKALLTIPSQGGIVNLPAV
IVTLVITWLLSRGTKESKRVNNIMVLIKIGIVVLFIAVGVFYVKPENWIPFAPYGLSGVFAGGAAVFFAFLGFDALATSA
EEVKNPQRDLPIGIIASLVICTIIYVVVCLVMTGMVSYKELDVPEAMAYVLEVVGQDKVAGIIAIGAVIGIMAVIFAYIY
ATTRVFFAMSRDGLLPESFAKINKKTEAPTFTVWLTGIGSALIAGFIDLKELSNLANIGALLTFAMVGVSVIILRKTHPK
LQRGFMVPLVPILPIISIACCLFLMVNLPLKTWMYFGAWLAIGVVVYFVYSKKHSHLKDDGSSQDNLEQAN
>Mature_470_residues
ANLFKKKSVTQLLGESKSKTLTKTLGAFDLTMLGIGAIIGTGVLVLTGLVAARDAGPAVIFSFMIAAIVCGFAALCYAEV
ASTLPVSGSVYTYSYATIGEFVAHLMGWTLLSVYVVTTAAVAGGWTGYFHNLVSGLGLEIPKALLTIPSQGGIVNLPAVI
VTLVITWLLSRGTKESKRVNNIMVLIKIGIVVLFIAVGVFYVKPENWIPFAPYGLSGVFAGGAAVFFAFLGFDALATSAE
EVKNPQRDLPIGIIASLVICTIIYVVVCLVMTGMVSYKELDVPEAMAYVLEVVGQDKVAGIIAIGAVIGIMAVIFAYIYA
TTRVFFAMSRDGLLPESFAKINKKTEAPTFTVWLTGIGSALIAGFIDLKELSNLANIGALLTFAMVGVSVIILRKTHPKL
QRGFMVPLVPILPIISIACCLFLMVNLPLKTWMYFGAWLAIGVVVYFVYSKKHSHLKDDGSSQDNLEQAN

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=431, Percent_Identity=34.8027842227378, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI258614005, Length=425, Percent_Identity=36, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI258614003, Length=425, Percent_Identity=36, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI258645169, Length=425, Percent_Identity=35.5294117647059, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI181337167, Length=393, Percent_Identity=35.3689567430025, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI114326544, Length=433, Percent_Identity=32.5635103926097, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI114326550, Length=433, Percent_Identity=32.5635103926097, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI110347453, Length=403, Percent_Identity=34.4913151364764, Blast_Score=211, Evalue=2e-54,
Organism=Homo sapiens, GI186910308, Length=443, Percent_Identity=25.2821670428894, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI186910306, Length=443, Percent_Identity=25.2821670428894, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI186910304, Length=443, Percent_Identity=25.2821670428894, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI33286428, Length=469, Percent_Identity=27.0788912579957, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI115648063, Length=435, Percent_Identity=25.2873563218391, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI115648022, Length=435, Percent_Identity=25.2873563218391, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI7657683, Length=378, Percent_Identity=25.6613756613757, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI187423910, Length=449, Percent_Identity=23.162583518931, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI7657591, Length=449, Percent_Identity=23.162583518931, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI71979932, Length=198, Percent_Identity=29.2929292929293, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI87081708, Length=490, Percent_Identity=20.8163265306122, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081869, Length=417, Percent_Identity=26.6187050359712, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790653, Length=479, Percent_Identity=24.8434237995825, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082023, Length=445, Percent_Identity=25.8426966292135, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788480, Length=445, Percent_Identity=23.8202247191011, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786694, Length=334, Percent_Identity=25.748502994012, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789017, Length=407, Percent_Identity=23.8329238329238, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786302, Length=430, Percent_Identity=21.1627906976744, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082250, Length=372, Percent_Identity=23.9247311827957, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367353, Length=337, Percent_Identity=22.2551928783383, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786908, Length=339, Percent_Identity=23.598820058997, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790584, Length=279, Percent_Identity=25.089605734767, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87081915, Length=409, Percent_Identity=22.9828850855746, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=390, Percent_Identity=34.6153846153846, Blast_Score=237, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI17533459, Length=409, Percent_Identity=33.9853300733496, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17531343, Length=404, Percent_Identity=32.6732673267327, Blast_Score=201, Evalue=8e-52,
Organism=Caenorhabditis elegans, GI17540018, Length=429, Percent_Identity=27.039627039627, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17537453, Length=387, Percent_Identity=24.8062015503876, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71982612, Length=415, Percent_Identity=22.6506024096386, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982608, Length=415, Percent_Identity=22.6506024096386, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17568033, Length=447, Percent_Identity=23.7136465324385, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32566699, Length=374, Percent_Identity=24.5989304812834, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI32566695, Length=418, Percent_Identity=22.7272727272727, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193208714, Length=418, Percent_Identity=22.7272727272727, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24666159, Length=411, Percent_Identity=38.4428223844282, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI221512776, Length=411, Percent_Identity=38.4428223844282, Blast_Score=277, Evalue=9e-75,
Organism=Drosophila melanogaster, GI24668806, Length=423, Percent_Identity=34.9881796690307, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI21356285, Length=423, Percent_Identity=34.9881796690307, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI24668802, Length=423, Percent_Identity=34.9881796690307, Blast_Score=254, Evalue=7e-68,
Organism=Drosophila melanogaster, GI24667468, Length=413, Percent_Identity=35.3510895883777, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI161077963, Length=403, Percent_Identity=36.4764267990074, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI281366235, Length=410, Percent_Identity=33.6585365853659, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI116007820, Length=410, Percent_Identity=33.6585365853659, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI116007818, Length=410, Percent_Identity=33.6585365853659, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI85725152, Length=410, Percent_Identity=33.6585365853659, Blast_Score=197, Evalue=1e-50,
Organism=Drosophila melanogaster, GI21357367, Length=445, Percent_Identity=27.6404494382022, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI221331183, Length=467, Percent_Identity=26.1241970021413, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17647653, Length=467, Percent_Identity=26.1241970021413, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24664379, Length=467, Percent_Identity=26.1241970021413, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24651635, Length=400, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24651633, Length=400, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45550968, Length=467, Percent_Identity=23.982869379015, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921172, Length=467, Percent_Identity=23.982869379015, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24641995, Length=402, Percent_Identity=24.3781094527363, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641993, Length=402, Percent_Identity=24.3781094527363, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50279; Mature: 50147

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ANLFKKKSVTQLLGESKSKTLTKTLGAFDLTMLGIGAIIGTGVLVLTGLVAARDAGPAV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH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HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]