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The map label for this gene is mhpC [C]

Identifier: 218231822

GI number: 218231822

Start: 3185361

End: 3186263

Strand: Reverse

Name: mhpC [C]

Synonym: BCB4264_A3303

Alternate gene names: 218231822

Gene position: 3186263-3185361 (Counterclockwise)

Preceding gene: 218233882

Following gene: 218231243

Centisome position: 58.8

GC content: 35.55

Gene sequence:

>903_bases
ATGATTAAGCCTGCAACAATGGAGTTTGTTTCACTATCGAACGGAGAAACGATTGCATATCAGGAAGTTGGAAGGCGAAA
TACAGATATTCTTGTACTCATTCACGGGAACATGACATCGTCACAACATTGGGATTTAGTTATTGAAAAGTTGCAAGATC
AATACCATATTTACGCTCTTGATTTAAGAGGGTTTGGACAATCAACGTATAATCAGTCGATAGATTCATTACAAGACTTT
GCAGACGATGTAAAATTATTTATTGACGAGTTAAAGCTAGAGAAATTTTCATTAATGGGCTGGTCAATGGGTGGTGGCGT
TGCGATGCAATTTACAGCGAATCACCCAACTTTTGTAGAAAAGTTAATTTTAGTAGAATCAGTAGGAATGAAAGGATACC
CAATCTTTAAAAAAGATACGAATGGGCAGCCGATTGTATCAAGTTTAGTAAAGACGAAAGAAGAAATTGCGCAAGATCCA
GTACAAATCGCTCCAGTATTAGATGCGATAAAAAATATGAACAAACTATATTACCGTACAGTATGGAATCTATTAATATA
TACACATAATCAACCTGAACCGGATCGTTATGAAAAGTATTTAGATGATATGTTAACGCAACGTAATTTCGTAGATGTGA
ATTATGCGCTCATTACATTTAATATTTCAGATGAACATAATGGGGTTGTAGAGGGAAGTAAACAAATTCATCGTATTAAA
GCGCCAACACTCGTCATACAAGGTGATAGAGATTATGTCGTACCGCAAGTAGTCGGTGAGGAATTAGCGAAACATTTGCC
AAATGCAGAGTTGAAGGTATTAGAAGATTGCGGACACTCGCCGTTTATTGATTGTTTAGATGTATTTATAAAACATGTAG
AGAATTGGTTAGAACAGAAATAA

Upstream 100 bases:

>100_bases
AAATTCTTATAGGTTTTATGTTGCGAACGTATATTCTACGTGCTATTCTTTAATTAAGTAAAGAATTTTCTTTCTATTAA
ATAGAATGGGGGAACTTGTG

Downstream 100 bases:

>100_bases
TCCCCGAAATGAAAGGTATTGCATATACTATAACATTGTAGGTAAAAGGGGAGATTATCAATGCATCATCCGTTCTTAAT
TGTGCATTCTCCATATAATC

Product: 3-Oxoadipate enol-lactonase

Products: 3-oxoadipate

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MIKPATMEFVSLSNGETIAYQEVGRRNTDILVLIHGNMTSSQHWDLVIEKLQDQYHIYALDLRGFGQSTYNQSIDSLQDF
ADDVKLFIDELKLEKFSLMGWSMGGGVAMQFTANHPTFVEKLILVESVGMKGYPIFKKDTNGQPIVSSLVKTKEEIAQDP
VQIAPVLDAIKNMNKLYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGSKQIHRIK
APTLVIQGDRDYVVPQVVGEELAKHLPNAELKVLEDCGHSPFIDCLDVFIKHVENWLEQK

Sequences:

>Translated_300_residues
MIKPATMEFVSLSNGETIAYQEVGRRNTDILVLIHGNMTSSQHWDLVIEKLQDQYHIYALDLRGFGQSTYNQSIDSLQDF
ADDVKLFIDELKLEKFSLMGWSMGGGVAMQFTANHPTFVEKLILVESVGMKGYPIFKKDTNGQPIVSSLVKTKEEIAQDP
VQIAPVLDAIKNMNKLYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGSKQIHRIK
APTLVIQGDRDYVVPQVVGEELAKHLPNAELKVLEDCGHSPFIDCLDVFIKHVENWLEQK
>Mature_300_residues
MIKPATMEFVSLSNGETIAYQEVGRRNTDILVLIHGNMTSSQHWDLVIEKLQDQYHIYALDLRGFGQSTYNQSIDSLQDF
ADDVKLFIDELKLEKFSLMGWSMGGGVAMQFTANHPTFVEKLILVESVGMKGYPIFKKDTNGQPIVSSLVKTKEEIAQDP
VQIAPVLDAIKNMNKLYYRTVWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGSKQIHRIK
APTLVIQGDRDYVVPQVVGEELAKHLPNAELKVLEDCGHSPFIDCLDVFIKHVENWLEQK

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=308, Percent_Identity=25.6493506493506, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17508535, Length=309, Percent_Identity=25.5663430420712, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.1.1.24

Molecular weight: Translated: 34307; Mature: 34307

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKPATMEFVSLSNGETIAYQEVGRRNTDILVLIHGNMTSSQHWDLVIEKLQDQYHIYAL
CCCCCCCCEEECCCCCEEEHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEE
DLRGFGQSTYNQSIDSLQDFADDVKLFIDELKLEKFSLMGWSMGGGVAMQFTANHPTFVE
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECEECCCCEEEEEECCCHHHHH
KLILVESVGMKGYPIFKKDTNGQPIVSSLVKTKEEIAQDPVQIAPVLDAIKNMNKLYYRT
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGSKQIHRIK
HHHHHEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCCHHHHEEC
APTLVIQGDRDYVVPQVVGEELAKHLPNAELKVLEDCGHSPFIDCLDVFIKHVENWLEQK
CCEEEEECCCCEECHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKPATMEFVSLSNGETIAYQEVGRRNTDILVLIHGNMTSSQHWDLVIEKLQDQYHIYAL
CCCCCCCCEEECCCCCEEEHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEE
DLRGFGQSTYNQSIDSLQDFADDVKLFIDELKLEKFSLMGWSMGGGVAMQFTANHPTFVE
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECEECCCCEEEEEECCCHHHHH
KLILVESVGMKGYPIFKKDTNGQPIVSSLVKTKEEIAQDPVQIAPVLDAIKNMNKLYYRT
HHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VWNLLIYTHNQPEPDRYEKYLDDMLTQRNFVDVNYALITFNISDEHNGVVEGSKQIHRIK
HHHHHEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCCCCCHHHHEEC
APTLVIQGDRDYVVPQVVGEELAKHLPNAELKVLEDCGHSPFIDCLDVFIKHVENWLEQK
CCEEEEECCCCEECHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-oxoadipate enol-lactone; H2O

Specific reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]