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The map label for this gene is rihB [H]

Identifier: 218231816

GI number: 218231816

Start: 2268700

End: 2269641

Strand: Reverse

Name: rihB [H]

Synonym: BCB4264_A2364

Alternate gene names: 218231816

Gene position: 2269641-2268700 (Counterclockwise)

Preceding gene: 218234886

Following gene: 218232423

Centisome position: 41.88

GC content: 40.13

Gene sequence:

>942_bases
ATGAAGAAAAAAGTGTACTTCAATCATGATGGCGGCGTAGATGATTTAATTTCATTATTTTTATTACTTCAAATGGAAAA
CGTTGAACTTACCGGTGTATCTGTTATCCCAGCAGACTGCTATTTAGAACCCGCAATGTCTGCCAGTCGTAAAATTATCG
ATCGTTTCGGCAAAGGTAATATTGCCGTAGCCGCTTCAAACTCTCGCGGGCAAAACCCGTTTCCGAAAGACTGGCGGATG
CATGCATTTTATGTAGATGCTTTACCAATTTTAAATGAGTCTGGAAAAGTTGTAACACCCGTGGTGGCAAAGCCTGCACA
TCACCATTTAATAGAAACACTTCTACAAACGGAAGGAAAAACAACTTTATTATTTACCGGGCCCCTAACTGACCTTGCTC
GTGCATTATATGAAACTCCCATCATCGAAGATAAAATTGAACGTCTCGTTTGGATGGGTGGTACATTTCTTACAGCAGGC
AATGTACATGAACCAGAGCATGATGGAACAGCTGAGTGGAATTCGTTTTGGGACCCTGAAGCAGTGGCTCGTGTATGGGA
TGCAAAAATTAAAATCGACTTAGTGACACTAGAAAGTACAAACCAAGTTCCGTTAACTATAAACATACGTGAACAATGGG
CAAAAGAACGAAAGTATATTGGTATGGATTTCCTTGGTCAATGCTATGCAATGGTTCCCCCTCTCGTTCACTTCTCAACG
AACTCTACCTACTATTTATGGGATGTACTAACTACCGCGCTTGTCGGAAACACTAACCTTGCAAAAACTGAAACAATTAA
TAGTATTGTTCATACATACGGACCAAGCCAAGGACGTACAGAGGAAACTGCTGATGGACGACCTGTAAATGTCGTTTACG
ATGTAAAACACGATGTTTTCTTTGAATATATTACTAAATTAGCTAAAAAAGCTGCTACTTGA

Upstream 100 bases:

>100_bases
GCTACTGATTAATGGAGAAATTGAAGTGGTGGAAATTATTGATGACTTCTCCTCAATTCATATTTAATTTCTAACTAAAT
CATATAGGATGGAGATTACA

Downstream 100 bases:

>100_bases
AACCTCAATAACACGAAAAAAATTTATTAAGAATGATATACTTTAATTAATATAACATGAGGTGATAAGATGGATTATGA
GTTACTAAAAGAACGAATAG

Product: inosine-uridine preferring nucleoside hydrolase family protein

Products: NA

Alternate protein names: Cytidine/uridine-specific hydrolase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MKKKVYFNHDGGVDDLISLFLLLQMENVELTGVSVIPADCYLEPAMSASRKIIDRFGKGNIAVAASNSRGQNPFPKDWRM
HAFYVDALPILNESGKVVTPVVAKPAHHHLIETLLQTEGKTTLLFTGPLTDLARALYETPIIEDKIERLVWMGGTFLTAG
NVHEPEHDGTAEWNSFWDPEAVARVWDAKIKIDLVTLESTNQVPLTINIREQWAKERKYIGMDFLGQCYAMVPPLVHFST
NSTYYLWDVLTTALVGNTNLAKTETINSIVHTYGPSQGRTEETADGRPVNVVYDVKHDVFFEYITKLAKKAAT

Sequences:

>Translated_313_residues
MKKKVYFNHDGGVDDLISLFLLLQMENVELTGVSVIPADCYLEPAMSASRKIIDRFGKGNIAVAASNSRGQNPFPKDWRM
HAFYVDALPILNESGKVVTPVVAKPAHHHLIETLLQTEGKTTLLFTGPLTDLARALYETPIIEDKIERLVWMGGTFLTAG
NVHEPEHDGTAEWNSFWDPEAVARVWDAKIKIDLVTLESTNQVPLTINIREQWAKERKYIGMDFLGQCYAMVPPLVHFST
NSTYYLWDVLTTALVGNTNLAKTETINSIVHTYGPSQGRTEETADGRPVNVVYDVKHDVFFEYITKLAKKAAT
>Mature_313_residues
MKKKVYFNHDGGVDDLISLFLLLQMENVELTGVSVIPADCYLEPAMSASRKIIDRFGKGNIAVAASNSRGQNPFPKDWRM
HAFYVDALPILNESGKVVTPVVAKPAHHHLIETLLQTEGKTTLLFTGPLTDLARALYETPIIEDKIERLVWMGGTFLTAG
NVHEPEHDGTAEWNSFWDPEAVARVWDAKIKIDLVTLESTNQVPLTINIREQWAKERKYIGMDFLGQCYAMVPPLVHFST
NSTYYLWDVLTTALVGNTNLAKTETINSIVHTYGPSQGRTEETADGRPVNVVYDVKHDVFFEYITKLAKKAAT

Specific function: Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides [H]

COG id: COG1957

COG function: function code F; Inosine-uridine nucleoside N-ribohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IUNH family. RihB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788486, Length=215, Percent_Identity=26.5116279069767, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015910
- InterPro:   IPR023186
- InterPro:   IPR001910
- InterPro:   IPR022977 [H]

Pfam domain/function: PF01156 IU_nuc_hydro [H]

EC number: =3.2.2.8 [H]

Molecular weight: Translated: 35066; Mature: 35066

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKVYFNHDGGVDDLISLFLLLQMENVELTGVSVIPADCYLEPAMSASRKIIDRFGKGN
CCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEEEEECCHHEECHHHHHHHHHHHHCCCCC
IAVAASNSRGQNPFPKDWRMHAFYVDALPILNESGKVVTPVVAKPAHHHLIETLLQTEGK
EEEEECCCCCCCCCCCCCEEEEEEEEEEHEECCCCCEEEHHHCCCHHHHHHHHHHHCCCC
TTLLFTGPLTDLARALYETPIIEDKIERLVWMGGTFLTAGNVHEPEHDGTAEWNSFWDPE
EEEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHH
AVARVWDAKIKIDLVTLESTNQVPLTINIREQWAKERKYIGMDFLGQCYAMVPPLVHFST
HHHHHHCCEEEEEEEEECCCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECC
NSTYYLWDVLTTALVGNTNLAKTETINSIVHTYGPSQGRTEETADGRPVNVVYDVKHDVF
CCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHH
FEYITKLAKKAAT
HHHHHHHHHHCCC
>Mature Secondary Structure
MKKKVYFNHDGGVDDLISLFLLLQMENVELTGVSVIPADCYLEPAMSASRKIIDRFGKGN
CCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEEEEECCHHEECHHHHHHHHHHHHCCCCC
IAVAASNSRGQNPFPKDWRMHAFYVDALPILNESGKVVTPVVAKPAHHHLIETLLQTEGK
EEEEECCCCCCCCCCCCCEEEEEEEEEEHEECCCCCEEEHHHCCCHHHHHHHHHHHCCCC
TTLLFTGPLTDLARALYETPIIEDKIERLVWMGGTFLTAGNVHEPEHDGTAEWNSFWDPE
EEEEEECCHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCHH
AVARVWDAKIKIDLVTLESTNQVPLTINIREQWAKERKYIGMDFLGQCYAMVPPLVHFST
HHHHHHCCEEEEEEEEECCCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHCCCEEEECC
NSTYYLWDVLTTALVGNTNLAKTETINSIVHTYGPSQGRTEETADGRPVNVVYDVKHDVF
CCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHH
FEYITKLAKKAAT
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA