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The map label for this gene is arcD [H]

Identifier: 218231726

GI number: 218231726

Start: 399096

End: 400511

Strand: Direct

Name: arcD [H]

Synonym: BCB4264_A0422

Alternate gene names: 218231726

Gene position: 399096-400511 (Clockwise)

Preceding gene: 218232375

Following gene: 218231136

Centisome position: 7.36

GC content: 36.16

Gene sequence:

>1416_bases
ATGGGTGAAGATAAGAAATTAGGGTTGTTTACACTAACGGCTCTTGTAGTTGGGTCTATGATTGGCGGTGGAGCCTTTAA
TTTAGCGAGTGATATGGCAAAAGGTGCTGGTGCTGGAGCCATTATTATTGGCTGGGTTATAACAGGAATTGGGATGATTG
CACTCGGATTATCTTTTCAAAATCTAACTGTAAAACGGCCAGATTTAGATGGTGGTATTTTTAGCTATGCAAAAGCAGGG
TTTGGTAATTTTATGGGGTTTAATAGTGCGTGGGGATACTGGCTATCTGCTTGGCTTGGGAATGTAGCTTACGGTACATT
ATTGTTTTCTTCATTAGGATATTTCTTCCCGATCTTTGAAGGCGGTCAAAATGTAGAATCCATTATTGGTGCAAGCGTAT
TATTATGGTGTGTTCACATGTTAATTTTACGTGGAGTTCAATCAGCAGCCCTTGTGAATTTAGTAACTACAATCGCAAAA
TTAGTACCTGTATTTGTATTTATTGTCATAGGAATCTTTGCGTTTCATATTGATACGTTCTTAGATGGATTTTGGGGGCA
AACTGGTTCTTTTTCATGGGGAGCAGTTGGCAGCCAAGTTAAAAGTACAATGCTTGTAACTTTATGGGTATTTATTGGGG
TAGAAGGGGCTGTTGTTTTATCCAGTCGAGCAAAAAATAGAAGTGATGTAGGGAAAGCAACCGTTATTGGCTTAATTGGT
ACACTCATCATTTACATTTTAATCACATTATTGTCTCTTGGACTTATGCAGCAAGCAGACATTGCAGGTTTGAAAAATCC
GGCTATGGCTTATTTATTTGAAAGTGTTGTTGGAAAATGGGGTGCTATCTTTATTAATTTAGGTTTAGTCATCTCTGTAT
TAGGTGCTTGGTTAGGTTGGACTTTGCTCGCTTCTGAAATTCCATATTTAGCGGCTAAAGATGGAGTATTTCCAAAATGG
TTCGCAAAAGAAAATAAAAATAAGGCTCCAGTAAATTCATTATGGATAACAAATGGTTTAATACAAATATTCTTGTTAAC
ATTCGTCGTTTCTGATCAGGCGTATAACTTTGCATTCTCTTTAGCATCTTCAGCTATTTTAATCCCATATGCTTTTTCAG
CATTTTATCAACTGAAGCATAGCTTAAAGTCTGAAGAAGCAGATCGAAATAAAAATATAATAATTGGCTTGATCGCAAGT
ATTTATGGCGTGTGGTTAGTTTATGCAGCCGGTTTAGAGTATTTATTATTAACAATGACTTTATATGCGCCAGGTATTTT
TATTTTTTACAATGTTCAAAAGCAAAAGAGTTCGAAGCAAATATTTACTCGAGTGGAATTAGCATCATCCGTAGCAATTG
GTGCTTTAGCATTCTTTGCGATTTATGGATTAATTACAGGCAGTATTACTTTATAA

Upstream 100 bases:

>100_bases
AAGAAGAAAGGGAGTCTTCCTTTCTTCTTTCTCCTCCTTTAGACACGATCATTCACTATTGCTTTTGTATTGTTATTGCA
ATTTAAGAGAGGTGAGTGGA

Downstream 100 bases:

>100_bases
AGCGCTGTGAAAGCGAAATCAACTGGAGGGCTGGAATATGGCACGAAGAAAAATTGTAGTTGCACTAGGGGGAAATGCGA
TACAGTCTGGAGAAGCTACT

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MGEDKKLGLFTLTALVVGSMIGGGAFNLASDMAKGAGAGAIIIGWVITGIGMIALGLSFQNLTVKRPDLDGGIFSYAKAG
FGNFMGFNSAWGYWLSAWLGNVAYGTLLFSSLGYFFPIFEGGQNVESIIGASVLLWCVHMLILRGVQSAALVNLVTTIAK
LVPVFVFIVIGIFAFHIDTFLDGFWGQTGSFSWGAVGSQVKSTMLVTLWVFIGVEGAVVLSSRAKNRSDVGKATVIGLIG
TLIIYILITLLSLGLMQQADIAGLKNPAMAYLFESVVGKWGAIFINLGLVISVLGAWLGWTLLASEIPYLAAKDGVFPKW
FAKENKNKAPVNSLWITNGLIQIFLLTFVVSDQAYNFAFSLASSAILIPYAFSAFYQLKHSLKSEEADRNKNIIIGLIAS
IYGVWLVYAAGLEYLLLTMTLYAPGIFIFYNVQKQKSSKQIFTRVELASSVAIGALAFFAIYGLITGSITL

Sequences:

>Translated_471_residues
MGEDKKLGLFTLTALVVGSMIGGGAFNLASDMAKGAGAGAIIIGWVITGIGMIALGLSFQNLTVKRPDLDGGIFSYAKAG
FGNFMGFNSAWGYWLSAWLGNVAYGTLLFSSLGYFFPIFEGGQNVESIIGASVLLWCVHMLILRGVQSAALVNLVTTIAK
LVPVFVFIVIGIFAFHIDTFLDGFWGQTGSFSWGAVGSQVKSTMLVTLWVFIGVEGAVVLSSRAKNRSDVGKATVIGLIG
TLIIYILITLLSLGLMQQADIAGLKNPAMAYLFESVVGKWGAIFINLGLVISVLGAWLGWTLLASEIPYLAAKDGVFPKW
FAKENKNKAPVNSLWITNGLIQIFLLTFVVSDQAYNFAFSLASSAILIPYAFSAFYQLKHSLKSEEADRNKNIIIGLIAS
IYGVWLVYAAGLEYLLLTMTLYAPGIFIFYNVQKQKSSKQIFTRVELASSVAIGALAFFAIYGLITGSITL
>Mature_470_residues
GEDKKLGLFTLTALVVGSMIGGGAFNLASDMAKGAGAGAIIIGWVITGIGMIALGLSFQNLTVKRPDLDGGIFSYAKAGF
GNFMGFNSAWGYWLSAWLGNVAYGTLLFSSLGYFFPIFEGGQNVESIIGASVLLWCVHMLILRGVQSAALVNLVTTIAKL
VPVFVFIVIGIFAFHIDTFLDGFWGQTGSFSWGAVGSQVKSTMLVTLWVFIGVEGAVVLSSRAKNRSDVGKATVIGLIGT
LIIYILITLLSLGLMQQADIAGLKNPAMAYLFESVVGKWGAIFINLGLVISVLGAWLGWTLLASEIPYLAAKDGVFPKWF
AKENKNKAPVNSLWITNGLIQIFLLTFVVSDQAYNFAFSLASSAILIPYAFSAFYQLKHSLKSEEADRNKNIIIGLIASI
YGVWLVYAAGLEYLLLTMTLYAPGIFIFYNVQKQKSSKQIFTRVELASSVAIGALAFFAIYGLITGSITL

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=450, Percent_Identity=47.1111111111111, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI2367353, Length=417, Percent_Identity=30.4556354916067, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786908, Length=425, Percent_Identity=26.3529411764706, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1790575, Length=419, Percent_Identity=26.0143198090692, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082250, Length=362, Percent_Identity=25.9668508287293, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786302, Length=394, Percent_Identity=22.5888324873096, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50632; Mature: 50501

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GEDKKLGLFTLTALVVGSMIGGGAFNLASDMAKGAGAGAIIIGWVITGIGMIALGLSFQ
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC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HHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9053381; 11792842 [H]