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The map label for this gene is lgrD [H]

Identifier: 218231666

GI number: 218231666

Start: 428467

End: 432048

Strand: Direct

Name: lgrD [H]

Synonym: BCB4264_A0443

Alternate gene names: 218231666

Gene position: 428467-432048 (Clockwise)

Preceding gene: 218234291

Following gene: 218235509

Centisome position: 7.91

GC content: 32.77

Gene sequence:

>3582_bases
ATGAAATTAGCAATTTCTTATAATAAGATGGTAAAAGAATTTTTAGGAAAAGTAGAAGGGAGTATTAAAATACCTAAAGA
TGTGCAAGGAACAGAACTTGGGGTAAAAAGGAAAACGGAACTGTTTCCAAATTTGACTCACATTGTAGATTTAATAGGAG
CGACTGCAACGTGGTTATATCATATTTCTAAAGAAAAACATATTGTCGTGCTTTATCATGTAAGAGGAAGTTTATTTCCG
ATTATTATTGAAGTTTCTAATTTTCTCTCCTATGAAAGTTTGAATTTACAGATTGAAGAGCAACTGGAGCAAATTAAAGA
AATGAATGAGGAAGAAATAGAAAAGTTTCAAAACGGTAATACATTATATGAAATGTCACCTATTATTATTGGCGAAACAT
ATTATGAGCTACAAGACACGAATACATTACAATTTGTATTTAGTAAAAATATGCAAAGTGTAGAAATAATATTTAATAGT
GTTAATTGGAAAGAGACAACAATTACTCGTTATGCACAACAAATACAAGGTGTTTTAATTAATAAATCACAAAATAAGAA
TAATCATATAAATGATTTTAATATTATTACAGAGGCCGAGATGGCACTTTATAGTCAAGTGAATGATACGACAGCAGTAT
ATCCTGAGAAAAGTATCGTCGATATGTTCTATAATACTGTTACTCAATTTCCAAATCGTATAGCTTTATCTTCAAGGGAA
GGTACTTTAACTTATGAGGAGCTAAATAAAAAAAGTAATCAAATAGCTCATATGTTAATTAAAAACGGCGTCCAATTAGG
AGACTATGTTGGAATATTTATGAAACGTAGCATAGACACAGTAGTAAGTATGGTAGCTATATTAAAAGCTGGTGCAGCGT
ATGTTCCGATTGATCCAGATTATCCGGAAAGTAGAATACAGTACATTATTCAAGATAGCCAAGCGAAAGTTATATTGATG
AAAGAGACGCCTATAACATGTGATGGGGTTCAAACAGTTTCAATGTATGATAGTGAAACTTATGAAGATACAGATGTAAA
GTTGTCTATTCATTGTGATGGTGTAGCTTATATGATTTATACATCTGGTTCAACAGGGAATCCAAAGGGAACGATGTTAG
CACATAGAGGCGTTGTTAATCTGTATACTTGGATGAAAAAGCAATATGAATTGACAGAAGAGGATGTATTTGCCCAATTT
CCTTCCTTTAGTTTCGATGCTTCTGTATGGGAGTCATTTGCTTCTTTATTCTGTGGAGGAAACTTATATGTACTATTAGA
GGAAGAGCGATTGTCTGTAGAAGCATTTGCAAATGCAATCTATAAAGTGAAAGCAACTTCAATCTTGGCATTAGCAACAA
TTTTTGTTCGACAAGTAGCAACTTATTTGGCAGAAGAAGATATATATAAGCTAGCTTCCCTAAAAAGAATTGCGATTGGC
GGTGAAATGTTGCCTGTAGAGGTTATTAAATTGTGGAGAGAAAGAATAGGTACAAATGTTGAAATTCATAATGTATACGG
ACCGACAGAATGTACTGTAGTGACGACAACCTATAAAATACCTAGTCAGTTAAATGAGGATGTTGCGAGTATTCCCATTG
GTAAACCATGTGCTAATTATCAAGTTATGATTTTGGATGAGAATATGAATCTTTGTCCAATTGGTGTACCTGGTGAATTA
TATATAGATTCAGTGGGATTAGCAAAAGGGTATTTTAATAAGCCTAATAAAACAATTGAAGCTTTTATTCCGAACCCTTT
TAATCCTATAGTTAATATATACAAAACAGGTGATATCGTTAAGTTGCTAGAGGATGGAAATATAGAGTTTTTATATCGGA
AAGATGATCAAGTAAAAATTAGAGGACATCGTATTGAACTAGGCGAAATCCAAAGTAAAATTTCTCAAAATCATAATATA
AAAGAAAATGCTGTTTTTGCTAAGAAGAGTAAGGAAGGTAGCCAATATTTAATCGCGTTCTATACAACTTTAAATAAAAA
AGAAATACCAGAATTAGTTTATCAGTTACAAGAGCAATTACCAGATTATATGGTGCCATCTAAACTAATTTATATTAATG
AATTACCACTTACACCTAATAAAAAGATTGATGTTAAGAAGTTAGCTCAGTTAGAAGAAAAGTATGAACCGGTTCGGCTA
CAAGAATATGTTGCACCTTCTAATAAAGCAGAAAAACAAATAGCGAACGCCTGGGCGGAAGTATTAGGAATTTCAAAAGT
TGGAGTGCATGATGATTTCTTTACAATTGGTGGACATTCATTAAAAGTATTACGAGTCTTAACATTGTTAAAAGAAGATT
TCTCACATTTAACAATTCAAGATTTCTTTAAAGAAAGAACGATATATGGATTAGCTCGAATTGAGCGAGAAGTAAAAGTA
GAGAAAGAAGAAGTATTTCGTGAATATAAAGTGATTCACGAACCAGATACTATCACGTATGCAAACGTTTTGGAAGAAAA
CCAGATTTCAAATGTCTTTTTAACAGGAGCTACTGGTTATTTAGGATCACACATATTATATGAATTGTTGAGAGATACAT
CTGCTACTATTTATTGTTTAGTAAGACCAACTAAAGATGTGCAGCAAAGAATTATAGATACATTAACAGGCTACTTTAAT
GATGTATGTGAAGAATGGTTACAGCGTATACAGGCCGTAGCCGGTGATCTGGGAGAAGAGTATCTTGGGATGAGCGAAGA
AGAATTTATGTTCATCAGTTCTAAGATGGATACGATAATTCATTGCGGTGCAGATGTAAGACATTTTGGGGATGTAAAAC
AATTTGAAAATATAAATGTCCAAGGAACTAGCCGTATGCTAGCATTAGCGGAGAAAGGTGCTACATTCCATTTTATTTCT
ACAATTGGTATCCCGTTAGAATTAGCGGTAGATCAATGGGATACATACATGAAAACTGGTGATTTTAATTACAGTGTAGA
CTTAGAGAATGTATATTCAAATAGTAAACTACAAGCGGAAAACATTGTTCGTGAAGCAATGAAAAATGGTTTGCGCGGAA
ATATTTATCGTGCAGGTAATTTAGCATGTCATTCAGAAACAGGTTCGTTCCAACAAAATATTGAAGGAAACGCATTTTAT
CGTCTTATTAAAACAATGCTATTAATTGGGAAAGCACCAAATGTGAAGTGGAAAGTTGATTTCACACCAATTGATTTTGC
TAGTAAATCAATTGTATCGTATTTGCAAGATTCGCAAATTATAGGAGAGACGTTACATATTTGTCATCCACATCAAATTG
AGTTTGAACAATTTATACAGCTAATTGGAGAGTGTGGATACAATCTTGAAATGGTTCCACTTTCAGAATATGTAAATACC
GGACTTGCATTAGCGAAGGGAAATGAAGTAATAGCAGAGTTAATTGCTTCTCAAGTTGCAGGAGATGGAGCGCAGCAATC
TGAAATTGTAATGGGTACGCGTAGAACGAATAAATGGATTAAGAAAAAAGAATTGATAGTACCAGCAATTAATAAAGAAT
TTATTCAGCAGTTATTAGCTCATGGTGAAAAAGTTGGTTATTTTCCAAAAATAATGAAATGA

Upstream 100 bases:

>100_bases
CCCTTGATTATGAATTGAACGAATCTGCCCGTTAATAAGGGATGAAAAAGGTGTGAATTTTCACACCTTTATTATATTTA
AGAGAGGAATTTACATAAAT

Downstream 100 bases:

>100_bases
TTATGCATGCTTTTGTTTGTTCAATAAAATAAATCATGCTACAATGAAAACGAATTAAGGACCGGGGAGCCAATTGGCTG
AGAGGATGTAAGTAAACATC

Product: linear gramicidin synthetase subunit C

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 1193; Mature: 1193

Protein sequence:

>1193_residues
MKLAISYNKMVKEFLGKVEGSIKIPKDVQGTELGVKRKTELFPNLTHIVDLIGATATWLYHISKEKHIVVLYHVRGSLFP
IIIEVSNFLSYESLNLQIEEQLEQIKEMNEEEIEKFQNGNTLYEMSPIIIGETYYELQDTNTLQFVFSKNMQSVEIIFNS
VNWKETTITRYAQQIQGVLINKSQNKNNHINDFNIITEAEMALYSQVNDTTAVYPEKSIVDMFYNTVTQFPNRIALSSRE
GTLTYEELNKKSNQIAHMLIKNGVQLGDYVGIFMKRSIDTVVSMVAILKAGAAYVPIDPDYPESRIQYIIQDSQAKVILM
KETPITCDGVQTVSMYDSETYEDTDVKLSIHCDGVAYMIYTSGSTGNPKGTMLAHRGVVNLYTWMKKQYELTEEDVFAQF
PSFSFDASVWESFASLFCGGNLYVLLEEERLSVEAFANAIYKVKATSILALATIFVRQVATYLAEEDIYKLASLKRIAIG
GEMLPVEVIKLWRERIGTNVEIHNVYGPTECTVVTTTYKIPSQLNEDVASIPIGKPCANYQVMILDENMNLCPIGVPGEL
YIDSVGLAKGYFNKPNKTIEAFIPNPFNPIVNIYKTGDIVKLLEDGNIEFLYRKDDQVKIRGHRIELGEIQSKISQNHNI
KENAVFAKKSKEGSQYLIAFYTTLNKKEIPELVYQLQEQLPDYMVPSKLIYINELPLTPNKKIDVKKLAQLEEKYEPVRL
QEYVAPSNKAEKQIANAWAEVLGISKVGVHDDFFTIGGHSLKVLRVLTLLKEDFSHLTIQDFFKERTIYGLARIEREVKV
EKEEVFREYKVIHEPDTITYANVLEENQISNVFLTGATGYLGSHILYELLRDTSATIYCLVRPTKDVQQRIIDTLTGYFN
DVCEEWLQRIQAVAGDLGEEYLGMSEEEFMFISSKMDTIIHCGADVRHFGDVKQFENINVQGTSRMLALAEKGATFHFIS
TIGIPLELAVDQWDTYMKTGDFNYSVDLENVYSNSKLQAENIVREAMKNGLRGNIYRAGNLACHSETGSFQQNIEGNAFY
RLIKTMLLIGKAPNVKWKVDFTPIDFASKSIVSYLQDSQIIGETLHICHPHQIEFEQFIQLIGECGYNLEMVPLSEYVNT
GLALAKGNEVIAELIASQVAGDGAQQSEIVMGTRRTNKWIKKKELIVPAINKEFIQQLLAHGEKVGYFPKIMK

Sequences:

>Translated_1193_residues
MKLAISYNKMVKEFLGKVEGSIKIPKDVQGTELGVKRKTELFPNLTHIVDLIGATATWLYHISKEKHIVVLYHVRGSLFP
IIIEVSNFLSYESLNLQIEEQLEQIKEMNEEEIEKFQNGNTLYEMSPIIIGETYYELQDTNTLQFVFSKNMQSVEIIFNS
VNWKETTITRYAQQIQGVLINKSQNKNNHINDFNIITEAEMALYSQVNDTTAVYPEKSIVDMFYNTVTQFPNRIALSSRE
GTLTYEELNKKSNQIAHMLIKNGVQLGDYVGIFMKRSIDTVVSMVAILKAGAAYVPIDPDYPESRIQYIIQDSQAKVILM
KETPITCDGVQTVSMYDSETYEDTDVKLSIHCDGVAYMIYTSGSTGNPKGTMLAHRGVVNLYTWMKKQYELTEEDVFAQF
PSFSFDASVWESFASLFCGGNLYVLLEEERLSVEAFANAIYKVKATSILALATIFVRQVATYLAEEDIYKLASLKRIAIG
GEMLPVEVIKLWRERIGTNVEIHNVYGPTECTVVTTTYKIPSQLNEDVASIPIGKPCANYQVMILDENMNLCPIGVPGEL
YIDSVGLAKGYFNKPNKTIEAFIPNPFNPIVNIYKTGDIVKLLEDGNIEFLYRKDDQVKIRGHRIELGEIQSKISQNHNI
KENAVFAKKSKEGSQYLIAFYTTLNKKEIPELVYQLQEQLPDYMVPSKLIYINELPLTPNKKIDVKKLAQLEEKYEPVRL
QEYVAPSNKAEKQIANAWAEVLGISKVGVHDDFFTIGGHSLKVLRVLTLLKEDFSHLTIQDFFKERTIYGLARIEREVKV
EKEEVFREYKVIHEPDTITYANVLEENQISNVFLTGATGYLGSHILYELLRDTSATIYCLVRPTKDVQQRIIDTLTGYFN
DVCEEWLQRIQAVAGDLGEEYLGMSEEEFMFISSKMDTIIHCGADVRHFGDVKQFENINVQGTSRMLALAEKGATFHFIS
TIGIPLELAVDQWDTYMKTGDFNYSVDLENVYSNSKLQAENIVREAMKNGLRGNIYRAGNLACHSETGSFQQNIEGNAFY
RLIKTMLLIGKAPNVKWKVDFTPIDFASKSIVSYLQDSQIIGETLHICHPHQIEFEQFIQLIGECGYNLEMVPLSEYVNT
GLALAKGNEVIAELIASQVAGDGAQQSEIVMGTRRTNKWIKKKELIVPAINKEFIQQLLAHGEKVGYFPKIMK
>Mature_1193_residues
MKLAISYNKMVKEFLGKVEGSIKIPKDVQGTELGVKRKTELFPNLTHIVDLIGATATWLYHISKEKHIVVLYHVRGSLFP
IIIEVSNFLSYESLNLQIEEQLEQIKEMNEEEIEKFQNGNTLYEMSPIIIGETYYELQDTNTLQFVFSKNMQSVEIIFNS
VNWKETTITRYAQQIQGVLINKSQNKNNHINDFNIITEAEMALYSQVNDTTAVYPEKSIVDMFYNTVTQFPNRIALSSRE
GTLTYEELNKKSNQIAHMLIKNGVQLGDYVGIFMKRSIDTVVSMVAILKAGAAYVPIDPDYPESRIQYIIQDSQAKVILM
KETPITCDGVQTVSMYDSETYEDTDVKLSIHCDGVAYMIYTSGSTGNPKGTMLAHRGVVNLYTWMKKQYELTEEDVFAQF
PSFSFDASVWESFASLFCGGNLYVLLEEERLSVEAFANAIYKVKATSILALATIFVRQVATYLAEEDIYKLASLKRIAIG
GEMLPVEVIKLWRERIGTNVEIHNVYGPTECTVVTTTYKIPSQLNEDVASIPIGKPCANYQVMILDENMNLCPIGVPGEL
YIDSVGLAKGYFNKPNKTIEAFIPNPFNPIVNIYKTGDIVKLLEDGNIEFLYRKDDQVKIRGHRIELGEIQSKISQNHNI
KENAVFAKKSKEGSQYLIAFYTTLNKKEIPELVYQLQEQLPDYMVPSKLIYINELPLTPNKKIDVKKLAQLEEKYEPVRL
QEYVAPSNKAEKQIANAWAEVLGISKVGVHDDFFTIGGHSLKVLRVLTLLKEDFSHLTIQDFFKERTIYGLARIEREVKV
EKEEVFREYKVIHEPDTITYANVLEENQISNVFLTGATGYLGSHILYELLRDTSATIYCLVRPTKDVQQRIIDTLTGYFN
DVCEEWLQRIQAVAGDLGEEYLGMSEEEFMFISSKMDTIIHCGADVRHFGDVKQFENINVQGTSRMLALAEKGATFHFIS
TIGIPLELAVDQWDTYMKTGDFNYSVDLENVYSNSKLQAENIVREAMKNGLRGNIYRAGNLACHSETGSFQQNIEGNAFY
RLIKTMLLIGKAPNVKWKVDFTPIDFASKSIVSYLQDSQIIGETLHICHPHQIEFEQFIQLIGECGYNLEMVPLSEYVNT
GLALAKGNEVIAELIASQVAGDGAQQSEIVMGTRRTNKWIKKKELIVPAINKEFIQQLLAHGEKVGYFPKIMK

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=616, Percent_Identity=24.6753246753247, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI38505220, Length=509, Percent_Identity=25.5402750491159, Blast_Score=127, Evalue=7e-29,
Organism=Homo sapiens, GI42544132, Length=522, Percent_Identity=24.3295019157088, Blast_Score=123, Evalue=1e-27,
Organism=Homo sapiens, GI122937307, Length=587, Percent_Identity=22.9982964224872, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI28416953, Length=565, Percent_Identity=23.5398230088496, Blast_Score=101, Evalue=5e-21,
Organism=Homo sapiens, GI157311624, Length=528, Percent_Identity=24.0530303030303, Blast_Score=95, Evalue=4e-19,
Organism=Homo sapiens, GI157311622, Length=528, Percent_Identity=24.0530303030303, Blast_Score=95, Evalue=4e-19,
Organism=Homo sapiens, GI58082049, Length=528, Percent_Identity=23.8636363636364, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI156151445, Length=555, Percent_Identity=21.4414414414414, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI13375727, Length=532, Percent_Identity=23.4962406015038, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI115511026, Length=519, Percent_Identity=22.1579961464355, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI42544134, Length=335, Percent_Identity=22.9850746268657, Blast_Score=71, Evalue=6e-12,
Organism=Escherichia coli, GI1786801, Length=648, Percent_Identity=31.0185185185185, Blast_Score=315, Evalue=1e-86,
Organism=Escherichia coli, GI145693145, Length=543, Percent_Identity=23.7569060773481, Blast_Score=124, Evalue=4e-29,
Organism=Escherichia coli, GI1788107, Length=556, Percent_Identity=24.1007194244604, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1786810, Length=511, Percent_Identity=21.1350293542074, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1789201, Length=361, Percent_Identity=24.9307479224377, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17556356, Length=568, Percent_Identity=26.9366197183099, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17550940, Length=553, Percent_Identity=26.7631103074141, Blast_Score=139, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI32563687, Length=487, Percent_Identity=24.2299794661191, Blast_Score=111, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17558820, Length=487, Percent_Identity=24.435318275154, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560308, Length=501, Percent_Identity=22.1556886227545, Blast_Score=86, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560140, Length=478, Percent_Identity=21.1297071129707, Blast_Score=83, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17551278, Length=555, Percent_Identity=21.8018018018018, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559526, Length=345, Percent_Identity=22.8985507246377, Blast_Score=70, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=1238, Percent_Identity=25.767366720517, Blast_Score=328, Evalue=3e-90,
Organism=Drosophila melanogaster, GI24648676, Length=592, Percent_Identity=26.0135135135135, Blast_Score=178, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24581924, Length=528, Percent_Identity=23.8636363636364, Blast_Score=94, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21355181, Length=512, Percent_Identity=24.4140625, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24656500, Length=505, Percent_Identity=22.3762376237624, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573762, Length=131, Percent_Identity=33.587786259542, Blast_Score=74, Evalue=8e-13,
Organism=Drosophila melanogaster, GI20129837, Length=160, Percent_Identity=30.625, Blast_Score=71, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24652250, Length=160, Percent_Identity=30.625, Blast_Score=71, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 135442; Mature: 135442

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAISYNKMVKEFLGKVEGSIKIPKDVQGTELGVKRKTELFPNLTHIVDLIGATATWLY
CEEEEHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHE
HISKEKHIVVLYHVRGSLFPIIIEVSNFLSYESLNLQIEEQLEQIKEMNEEEIEKFQNGN
EECCCCEEEEEEEECCCCEEEEEEHHHHCCCHHCCEEHHHHHHHHHHCCHHHHHHHHCCC
TLYEMSPIIIGETYYELQDTNTLQFVFSKNMQSVEIIFNSVNWKETTITRYAQQIQGVLI
EEEEECCEEEECEEEEECCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEE
NKSQNKNNHINDFNIITEAEMALYSQVNDTTAVYPEKSIVDMFYNTVTQFPNRIALSSRE
ECCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCEEECCCC
GTLTYEELNKKSNQIAHMLIKNGVQLGDYVGIFMKRSIDTVVSMVAILKAGAAYVPIDPD
CCEEHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
YPESRIQYIIQDSQAKVILMKETPITCDGVQTVSMYDSETYEDTDVKLSIHCDGVAYMIY
CCHHHHHEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCEEEEEE
TSGSTGNPKGTMLAHRGVVNLYTWMKKQYELTEEDVFAQFPSFSFDASVWESFASLFCGG
ECCCCCCCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCC
NLYVLLEEERLSVEAFANAIYKVKATSILALATIFVRQVATYLAEEDIYKLASLKRIAIG
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GEMLPVEVIKLWRERIGTNVEIHNVYGPTECTVVTTTYKIPSQLNEDVASIPIGKPCANY
CCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEECCHHHCCHHHHCCCCCCCCCC
QVMILDENMNLCPIGVPGELYIDSVGLAKGYFNKPNKTIEAFIPNPFNPIVNIYKTGDIV
EEEEEECCCCEEEECCCCCEEEECCHHCCCCCCCCCCEEEEECCCCCHHHHEEEECCCEE
KLLEDGNIEFLYRKDDQVKIRGHRIELGEIQSKISQNHNIKENAVFAKKSKEGSQYLIAF
EEEECCCEEEEEECCCEEEEEEEEEEHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEEE
YTTLNKKEIPELVYQLQEQLPDYMVPSKLIYINELPLTPNKKIDVKKLAQLEEKYEPVRL
EECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCH
QEYVAPSNKAEKQIANAWAEVLGISKVGVHDDFFTIGGHSLKVLRVLTLLKEDFSHLTIQ
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHH
DFFKERTIYGLARIEREVKVEKEEVFREYKVIHEPDTITYANVLEENQISNVFLTGATGY
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCEEHHHHHHCCCCCEEEEECCCHH
LGSHILYELLRDTSATIYCLVRPTKDVQQRIIDTLTGYFNDVCEEWLQRIQAVAGDLGEE
HHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YLGMSEEEFMFISSKMDTIIHCGADVRHFGDVKQFENINVQGTSRMLALAEKGATFHFIS
HCCCCCHHEEEEECCCCEEEECCCCHHHHCCHHHHCCCCCCCCHHHHHHHHCCCEEEEEE
TIGIPLELAVDQWDTYMKTGDFNYSVDLENVYSNSKLQAENIVREAMKNGLRGNIYRAGN
CCCCCEEEEHHHHHHHHCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHCCCCCCEEECCC
LACHSETGSFQQNIEGNAFYRLIKTMLLIGKAPNVKWKVDFTPIDFASKSIVSYLQDSQI
EEEECCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCHH
IGETLHICHPHQIEFEQFIQLIGECGYNLEMVPLSEYVNTGLALAKGNEVIAELIASQVA
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHCCCEEEECCHHHHHHHHHHHHC
GDGAQQSEIVMGTRRTNKWIKKKELIVPAINKEFIQQLLAHGEKVGYFPKIMK
CCCCCCCCEEEECCHHHHHHHHHCCEEECCCHHHHHHHHHCCCCCCCCHHHCC
>Mature Secondary Structure
MKLAISYNKMVKEFLGKVEGSIKIPKDVQGTELGVKRKTELFPNLTHIVDLIGATATWLY
CEEEEHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHE
HISKEKHIVVLYHVRGSLFPIIIEVSNFLSYESLNLQIEEQLEQIKEMNEEEIEKFQNGN
EECCCCEEEEEEEECCCCEEEEEEHHHHCCCHHCCEEHHHHHHHHHHCCHHHHHHHHCCC
TLYEMSPIIIGETYYELQDTNTLQFVFSKNMQSVEIIFNSVNWKETTITRYAQQIQGVLI
EEEEECCEEEECEEEEECCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHCCEEE
NKSQNKNNHINDFNIITEAEMALYSQVNDTTAVYPEKSIVDMFYNTVTQFPNRIALSSRE
ECCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCEEECCCC
GTLTYEELNKKSNQIAHMLIKNGVQLGDYVGIFMKRSIDTVVSMVAILKAGAAYVPIDPD
CCEEHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
YPESRIQYIIQDSQAKVILMKETPITCDGVQTVSMYDSETYEDTDVKLSIHCDGVAYMIY
CCHHHHHEEEECCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCEEEEEE
TSGSTGNPKGTMLAHRGVVNLYTWMKKQYELTEEDVFAQFPSFSFDASVWESFASLFCGG
ECCCCCCCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCC
NLYVLLEEERLSVEAFANAIYKVKATSILALATIFVRQVATYLAEEDIYKLASLKRIAIG
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
GEMLPVEVIKLWRERIGTNVEIHNVYGPTECTVVTTTYKIPSQLNEDVASIPIGKPCANY
CCCCHHHHHHHHHHHCCCCEEEEEECCCCEEEEEEEEEECCHHHCCHHHHCCCCCCCCCC
QVMILDENMNLCPIGVPGELYIDSVGLAKGYFNKPNKTIEAFIPNPFNPIVNIYKTGDIV
EEEEEECCCCEEEECCCCCEEEECCHHCCCCCCCCCCEEEEECCCCCHHHHEEEECCCEE
KLLEDGNIEFLYRKDDQVKIRGHRIELGEIQSKISQNHNIKENAVFAKKSKEGSQYLIAF
EEEECCCEEEEEECCCEEEEEEEEEEHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEEE
YTTLNKKEIPELVYQLQEQLPDYMVPSKLIYINELPLTPNKKIDVKKLAQLEEKYEPVRL
EECCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCH
QEYVAPSNKAEKQIANAWAEVLGISKVGVHDDFFTIGGHSLKVLRVLTLLKEDFSHLTIQ
HHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHH
DFFKERTIYGLARIEREVKVEKEEVFREYKVIHEPDTITYANVLEENQISNVFLTGATGY
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEECCCCEEHHHHHHCCCCCEEEEECCCHH
LGSHILYELLRDTSATIYCLVRPTKDVQQRIIDTLTGYFNDVCEEWLQRIQAVAGDLGEE
HHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
YLGMSEEEFMFISSKMDTIIHCGADVRHFGDVKQFENINVQGTSRMLALAEKGATFHFIS
HCCCCCHHEEEEECCCCEEEECCCCHHHHCCHHHHCCCCCCCCHHHHHHHHCCCEEEEEE
TIGIPLELAVDQWDTYMKTGDFNYSVDLENVYSNSKLQAENIVREAMKNGLRGNIYRAGN
CCCCCEEEEHHHHHHHHCCCCCEEEEEHHHHHCCCCCCHHHHHHHHHHCCCCCCEEECCC
LACHSETGSFQQNIEGNAFYRLIKTMLLIGKAPNVKWKVDFTPIDFASKSIVSYLQDSQI
EEEECCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCHH
IGETLHICHPHQIEFEQFIQLIGECGYNLEMVPLSEYVNTGLALAKGNEVIAELIASQVA
HHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEHHHHHCCCEEEECCHHHHHHHHHHHHC
GDGAQQSEIVMGTRRTNKWIKKKELIVPAINKEFIQQLLAHGEKVGYFPKIMK
CCCCCCCCEEEECCHHHHHHHHHCCEEECCCHHHHHHHHHCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA