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The map label for this gene is yabD [H]

Identifier: 218231319

GI number: 218231319

Start: 43655

End: 44422

Strand: Direct

Name: yabD [H]

Synonym: BCB4264_A0044

Alternate gene names: 218231319

Gene position: 43655-44422 (Clockwise)

Preceding gene: 218235634

Following gene: 218232086

Centisome position: 0.81

GC content: 37.76

Gene sequence:

>768_bases
ATGTTGTTTGATACACATTCACATTTGAATGCAGAGCAATTCGAAGGAGATTTGCAAGAGGTTATTGCCCGAATGAAAGA
AGCGGGAGTTACTTATACAGTTGTTGTTGGTTTTGATGAAGTAACGATAAAAAAGGCGATGGAATTAGCTGAGGCCTATG
ATTTTATTTACGCTGCGGTTGGGTGGCACCCAGTTGATGCAATCGACATGACAGAAGAACATTTAGTTTGGTTAGAAGAA
CTTGCTTCTCATCCTAAAGTCGTTGCACTTGGAGAAATGGGCTTAGATTATCACTGGGATAAGTCTCCAAAAGAAATACA
GAAAGAAGTATTCCGTAAACAAATTGCATTAGCGAAAAAAGTAAAATTGCCGATTATTATACATAACCGCGATGCAACTC
AAGATATTGTTGATATTCTAGAAGAAGAGAATGCAGCTGAAGTAGGAGGCATTATGCATTGCTTTAGCGGCAGCGTAGAG
GTAGCAGAGCGATGTGTTGATATGAACTTTTTAATTTCGTTAGGTGGACCAGTTACATTTAAAAACGCTAAGAAGCCCAA
AGAGGTTGCTACGGAGATTCCATTAGAGAAATTGTTAATAGAGACGGATTGTCCGTATTTAACACCGCATCCATTTCGAG
GGAAACGAAATGAACCGAGTTATGTAAAACTCGTAGCAGAAGAAATTGCGAATTTAAAAGGAATTTCTTATGAGGAAGTA
GCAGAAATGACAACTAAAAATGCAAAAGTTTTATTTGGTGTTGAATAA

Upstream 100 bases:

>100_bases
CTATTTTTGCATTAAGATTGTAGTATTGTTATCGTTAAGTTATTAAAGAACTTATTTTTGTAGAATAAACTTGATTTCAA
TATAAAAGGAGTTATGTATT

Downstream 100 bases:

>100_bases
AAAAGAATGGGGAAACCTGTTCTTTTTTATTTTGAGAAGAACTAGTAGAAGTGATGAAGAAAATAAATGTGAATGATGAA
GTGTTACAATAAGGACAGAG

Product: deoxyribonuclease, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLFDTHSHLNAEQFEGDLQEVIARMKEAGVTYTVVVGFDEVTIKKAMELAEAYDFIYAAVGWHPVDAIDMTEEHLVWLEE
LASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQIALAKKVKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVE
VAERCVDMNFLISLGGPVTFKNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
AEMTTKNAKVLFGVE

Sequences:

>Translated_255_residues
MLFDTHSHLNAEQFEGDLQEVIARMKEAGVTYTVVVGFDEVTIKKAMELAEAYDFIYAAVGWHPVDAIDMTEEHLVWLEE
LASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQIALAKKVKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVE
VAERCVDMNFLISLGGPVTFKNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
AEMTTKNAKVLFGVE
>Mature_255_residues
MLFDTHSHLNAEQFEGDLQEVIARMKEAGVTYTVVVGFDEVTIKKAMELAEAYDFIYAAVGWHPVDAIDMTEEHLVWLEE
LASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQIALAKKVKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVE
VAERCVDMNFLISLGGPVTFKNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
AEMTTKNAKVLFGVE

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=34.469696969697, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=34.469696969697, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=34.0740740740741, Blast_Score=134, Evalue=6e-32,
Organism=Homo sapiens, GI226061614, Length=253, Percent_Identity=34.3873517786561, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI14042943, Length=271, Percent_Identity=30.2583025830258, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI226061595, Length=227, Percent_Identity=30.8370044052863, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI225903424, Length=160, Percent_Identity=35, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI225903439, Length=249, Percent_Identity=29.3172690763052, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=37.5968992248062, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI48994985, Length=262, Percent_Identity=34.3511450381679, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=34.7490347490347, Blast_Score=146, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=34.8754448398576, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=26.8199233716475, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17543026, Length=183, Percent_Identity=33.879781420765, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=224, Percent_Identity=33.4821428571429, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=32.9824561403509, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI221330018, Length=284, Percent_Identity=28.8732394366197, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24586117, Length=284, Percent_Identity=28.8732394366197, Blast_Score=103, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28655; Mature: 28655

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDTHSHLNAEQFEGDLQEVIARMKEAGVTYTVVVGFDEVTIKKAMELAEAYDFIYAAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHC
GWHPVDAIDMTEEHLVWLEELASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQIALAKK
CCCCCCHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVEVAERCVDMNFLISLGGPVTF
CCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCHHHEEECCCCEEE
KNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
CCCCCHHHHHHHCCHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AEMTTKNAKVLFGVE
HHHHCCCCEEEEECC
>Mature Secondary Structure
MLFDTHSHLNAEQFEGDLQEVIARMKEAGVTYTVVVGFDEVTIKKAMELAEAYDFIYAAV
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHC
GWHPVDAIDMTEEHLVWLEELASHPKVVALGEMGLDYHWDKSPKEIQKEVFRKQIALAKK
CCCCCCHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VKLPIIIHNRDATQDIVDILEEENAAEVGGIMHCFSGSVEVAERCVDMNFLISLGGPVTF
CCCCEEEECCCCHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHCHHHEEECCCCEEE
KNAKKPKEVATEIPLEKLLIETDCPYLTPHPFRGKRNEPSYVKLVAEEIANLKGISYEEV
CCCCCHHHHHHHCCHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHH
AEMTTKNAKVLFGVE
HHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]