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The map label for this gene is yrbD [H]

Identifier: 218231088

GI number: 218231088

Start: 2728296

End: 2729786

Strand: Reverse

Name: yrbD [H]

Synonym: BCB4264_A2842

Alternate gene names: 218231088

Gene position: 2729786-2728296 (Counterclockwise)

Preceding gene: 218235819

Following gene: 218233815

Centisome position: 50.37

GC content: 36.08

Gene sequence:

>1491_bases
ATGGAGAATTTAGTAGAATGGTTAGTAGGGCAAGTGTGGAGTATCGGTTTAGTTGTTTTTGCATTAGGGGCAGGCGTATA
TTTCACGATTGCAACACGTTTTTTGCAAATTCGTTATTTTAAAGAGATGATTAAACTATTATTTGAAGGAAAGAGTTCCG
AGACGGGAATATCATCTTTTCAGGCATTTTGTTTAGCCTTATCAGGAAGAGTTGGAATTGGTAATATTGCAGGGGTAGCG
ACAGCGATCGCTTTCGGCGGGCCTGGAGCTGTATTTTGGATGTGGGTAATGGCTTTGTTAGGGGCAGCGAGCGCGTTTGT
AGAATCAACATTATCTCAAGTATACAAAAGTAAAGTAGGGAATGAATATCGCGGCGGTACTCCATATTTCATTGAGAAAG
GTTTAAAAATGAAATGGTTTGCAGTCATTGTAGCGGTAGTTGTAACACTTTCATATGGCGTGTTATTACCAGGTATTCAA
TCTAGTAGTATCGCAGTTGGATTCGAAAACTCTAATGGTATTAGCAAATATATAACTGGTATATTTTTAGTCGTGTTACT
AGCAGCAATTATTTTTGGTGGTGTAAAGAGAATTGCCGGTGTTTCTCAAATGCTTGTGCCATTTATGGCAATTGGTTATG
TAATTGTTACATGTATCATATTAATTGCGAATGTAACGGAGATTCCAAGTATGTTTGCTTTAATTTTCTCTAGTGCATTT
GGTGTAAATGAAATGTTTGGTGGAATTGTTGGTGCAGCTATTGCATGGGGCGTAAAACGCGCTGTATTTTCAAACGTTGC
TGGTGTCGGAGAAGCAACGTATAGTTCGGCTGCTGCTGAAGTATCGCATCCTGCAAAACAAGGATTAGTTCAAGCGTTTT
CCGTATATATCGATACAATTGTCGTATGTACAGCGACAGCTCTTATGATATTAATTACAGGTATGTATAATGTTATACCT
GAAGGGAAAAGCGCTATTGTAAAAAACATAGGAAATGTGGAAGCAGGTCCAATTTATACGCAACAAGCAGTTGAAACTGT
GATGACAGGGTTTGGTCCAATATTTATTTCAATTGCAATTTTCTTTTTTGCATTTACAACGTTACTCGCTTATTACTATA
TTGCTGAAACGACACTTACTTATTTAGATCGTCAATTGAAGTATGGCTGGTTAAAACCAGTTTTAAAATTTGGATTTTTA
ATTATGGTTTACATCGGTAGTGTTGAATCAGCGTCGCTTTTATGGAATCTCGGAGATTTAGGAATCGGTAGTATGGCATG
GTTAAACTTAATCGCGATTCTATTATTAAGTAAAATCGCATTAAAAGTGTTAAAAGACTATGAAACGCAGAAAAAAGAAG
GGAAAGATCCAGTATTTAATCCTAAAAATGTGGGGATTGAAGGATTAACATTTTGGGAAGAAAGAAGTAAAGAGGTTGAA
AGAAAAAGTTCTAGAGAAAAAGTTATTGTAGATGATAATTTAAAATTATAA

Upstream 100 bases:

>100_bases
TGAAATAATGAAAGATGCGGACAACTAGAAAGTTTGATAATAGTTGTCCGTTTTCTTATATACAAAATTGCTTTTCCAAA
GAATGATAAGGGGGATTTGG

Downstream 100 bases:

>100_bases
TATAAATTAACTGAAAATTCTTAATTTAAAAGAAGGTATATTGCCTCCATTTCATCGCATACTACAATAGGTATGGATAA
TATGACTGGAGGGAATAAGA

Product: sodium/alanine symporter family protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MENLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSFQAFCLALSGRVGIGNIAGVA
TAIAFGGPGAVFWMWVMALLGAASAFVESTLSQVYKSKVGNEYRGGTPYFIEKGLKMKWFAVIVAVVVTLSYGVLLPGIQ
SSSIAVGFENSNGISKYITGIFLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIILIANVTEIPSMFALIFSSAF
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTIVVCTATALMILITGMYNVIP
EGKSAIVKNIGNVEAGPIYTQQAVETVMTGFGPIFISIAIFFFAFTTLLAYYYIAETTLTYLDRQLKYGWLKPVLKFGFL
IMVYIGSVESASLLWNLGDLGIGSMAWLNLIAILLLSKIALKVLKDYETQKKEGKDPVFNPKNVGIEGLTFWEERSKEVE
RKSSREKVIVDDNLKL

Sequences:

>Translated_496_residues
MENLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSFQAFCLALSGRVGIGNIAGVA
TAIAFGGPGAVFWMWVMALLGAASAFVESTLSQVYKSKVGNEYRGGTPYFIEKGLKMKWFAVIVAVVVTLSYGVLLPGIQ
SSSIAVGFENSNGISKYITGIFLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIILIANVTEIPSMFALIFSSAF
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTIVVCTATALMILITGMYNVIP
EGKSAIVKNIGNVEAGPIYTQQAVETVMTGFGPIFISIAIFFFAFTTLLAYYYIAETTLTYLDRQLKYGWLKPVLKFGFL
IMVYIGSVESASLLWNLGDLGIGSMAWLNLIAILLLSKIALKVLKDYETQKKEGKDPVFNPKNVGIEGLTFWEERSKEVE
RKSSREKVIVDDNLKL
>Mature_496_residues
MENLVEWLVGQVWSIGLVVFALGAGVYFTIATRFLQIRYFKEMIKLLFEGKSSETGISSFQAFCLALSGRVGIGNIAGVA
TAIAFGGPGAVFWMWVMALLGAASAFVESTLSQVYKSKVGNEYRGGTPYFIEKGLKMKWFAVIVAVVVTLSYGVLLPGIQ
SSSIAVGFENSNGISKYITGIFLVVLLAAIIFGGVKRIAGVSQMLVPFMAIGYVIVTCIILIANVTEIPSMFALIFSSAF
GVNEMFGGIVGAAIAWGVKRAVFSNVAGVGEATYSSAAAEVSHPAKQGLVQAFSVYIDTIVVCTATALMILITGMYNVIP
EGKSAIVKNIGNVEAGPIYTQQAVETVMTGFGPIFISIAIFFFAFTTLLAYYYIAETTLTYLDRQLKYGWLKPVLKFGFL
IMVYIGSVESASLLWNLGDLGIGSMAWLNLIAILLLSKIALKVLKDYETQKKEGKDPVFNPKNVGIEGLTFWEERSKEVE
RKSSREKVIVDDNLKL

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=493, Percent_Identity=35.9026369168357, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 53660; Mature: 53660

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCEEEECCCCCC
>Mature Secondary Structure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HHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]