Click here to switch to the map view.

The map label for this gene is npr [H]

Identifier: 218231055

GI number: 218231055

Start: 3269913

End: 3271610

Strand: Reverse

Name: npr [H]

Synonym: BCB4264_A3392

Alternate gene names: 218231055

Gene position: 3271610-3269913 (Counterclockwise)

Preceding gene: 218235717

Following gene: 218231401

Centisome position: 60.37

GC content: 34.57

Gene sequence:

>1698_bases
ATGAATAATTTCGTAAAGGTAGGTTTAACTACAGGAGTGGTGTTATCGGCGATTATGCCTTATGGAGGAGTACATGCGGA
AACAGAAGATTTAAAAGTGGAAACAAAGGAAGATACGTTCCGAACAGGTAATTTAACAGCACCTTCTCAAAATTCGGCAG
AAAATGTAGCAAAGGATGCACTAAAAGGAAAAACAGAACAAGCATTATCATCAAAGCAAGTTAATACGGAATCCAAAGTT
AATTATAATGTTACGCAAAGTCGTAAATCTTATGATGGTACTACATTGGTACGTCTTCAACAAACGTATGAAGGACGTGA
TGTATACGGATATCAACTAACAGCACATATTAATGATGATGGTGTACTTACGAGCGTTTCGGGAGATAGTGCCCAAAATT
TACAACAACAGGAAGATTTGAAACAACCTATTACTCTATCAGAAGAGGATGCAAAGAAACAGCTTTTCAACATCTATGGA
AATGATCTAACATTTATCGAAGAACCAGAAATTAAACAAGTGGTATATGTAGATGAAAATACAAATAAAGCTACAAACGC
ATATCAAATTACTTTTAGTGCATCTACACCTGAATATGTATCCGGTACAGTATTAATTGATGCTTTTGGTGGTAATCTAT
TAAAAGAACTCGTTCAAAAATTGGGTATACAAGTAGAGAGTAGTATTGTCCAATCTGCGACATCAAATAAATCAACAGAT
CCTTCAAAATTAACAGGTACAGGAAAAGATGACTTAGGTATTAATCGTACGTTTGGAATTACACAAAGAAGTGATGGAAC
GTACATGCTTGCAGATTATTCTCGTGGTAAGGGAATTGAAACATATACTGCTAATTATAAAGATTATAATAATTATAGAA
GAAATGTATGGGGTTATCTCGATGATTTAGTAACAAGTAATTCTACAAATTTTACAGATCCTAAAGCAGTTAGTGCCCAT
TATTTAGCAACGAAAGTATATGATTTTTATCAAGAAAAATATGGACGTAACAGCTTTGATAATAACGGACAAAAAGTAAT
TTCTGTCGTTCATGGTTGGAACACAAATGGTACGAATAAAGGAAATCCTAAGCAGTGGTTTAATGCATTTAGTAATGGCG
CTATGCTAGTATACGGAGATCCAATTGTTAGAGCATTTGATGTGGCAGGACATGAATTTACACACGCAGTTACAAGAAAT
GAGTCTGGACTTGAGTACGCAGGAGAAGCTGGTGCAATTAATGAAGCGTTATCTGATATTTTAGGAGTAGCCGTTGAAAA
GTATGCCAATAACGGAAAGTTCAATTGGACAATGGGAGAACAATCAGGTCGTATTTTTAGAGATATGAAAAACCCATCAT
CTATCTCTTCTAGATATCCAGAGGATTATAGGCATTATAATAACTTACCTATTGATGCTGACCACGATCATGGTGGTGTA
CACACGAACTCTAGCATTATTAATAAAGTAGCTTACTTGATTGCTAGTGGTGGAAGCCATAATGGAGTAAACGTACATGG
CATTGGAGAAGATAAAATGTTTGATATTTTCTATTATGCAAATACGGATGAATTAAATATGACTTCTGATTTTAAAGAAT
TAAAAGAAGCTTGTATTCGTGTAGCAACGAACTTATATGGTAAAGACTCATTAGAAGTACAAGCTGTCCAACAAGCCTTT
AAAGCAGCGTATATTTAA

Upstream 100 bases:

>100_bases
ATGTAAAAACGATTGGCTATAGTTAAAATTTTTTATCTATGCTTAAAATTCTAAAATACATTTATTTAATTTAATAATAC
GATTATAAAGGGGTAAAAAT

Downstream 100 bases:

>100_bases
TATTATTGTGATGAATTACAAACTCTTTCATTTTAATATAGTGATTAATTTGTATTTATAGAAAAAAACCTTGTAGAATT
TTTCTGCAAGGTTTTTTTGA

Product: bacillolysin

Products: NA

Alternate protein names: Neutral protease [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MNNFVKVGLTTGVVLSAIMPYGGVHAETEDLKVETKEDTFRTGNLTAPSQNSAENVAKDALKGKTEQALSSKQVNTESKV
NYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDDGVLTSVSGDSAQNLQQQEDLKQPITLSEEDAKKQLFNIYG
NDLTFIEEPEIKQVVYVDENTNKATNAYQITFSASTPEYVSGTVLIDAFGGNLLKELVQKLGIQVESSIVQSATSNKSTD
PSKLTGTGKDDLGINRTFGITQRSDGTYMLADYSRGKGIETYTANYKDYNNYRRNVWGYLDDLVTSNSTNFTDPKAVSAH
YLATKVYDFYQEKYGRNSFDNNGQKVISVVHGWNTNGTNKGNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRN
ESGLEYAGEAGAINEALSDILGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDHGGV
HTNSSIINKVAYLIASGGSHNGVNVHGIGEDKMFDIFYYANTDELNMTSDFKELKEACIRVATNLYGKDSLEVQAVQQAF
KAAYI

Sequences:

>Translated_565_residues
MNNFVKVGLTTGVVLSAIMPYGGVHAETEDLKVETKEDTFRTGNLTAPSQNSAENVAKDALKGKTEQALSSKQVNTESKV
NYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDDGVLTSVSGDSAQNLQQQEDLKQPITLSEEDAKKQLFNIYG
NDLTFIEEPEIKQVVYVDENTNKATNAYQITFSASTPEYVSGTVLIDAFGGNLLKELVQKLGIQVESSIVQSATSNKSTD
PSKLTGTGKDDLGINRTFGITQRSDGTYMLADYSRGKGIETYTANYKDYNNYRRNVWGYLDDLVTSNSTNFTDPKAVSAH
YLATKVYDFYQEKYGRNSFDNNGQKVISVVHGWNTNGTNKGNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRN
ESGLEYAGEAGAINEALSDILGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDHGGV
HTNSSIINKVAYLIASGGSHNGVNVHGIGEDKMFDIFYYANTDELNMTSDFKELKEACIRVATNLYGKDSLEVQAVQQAF
KAAYI
>Mature_565_residues
MNNFVKVGLTTGVVLSAIMPYGGVHAETEDLKVETKEDTFRTGNLTAPSQNSAENVAKDALKGKTEQALSSKQVNTESKV
NYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDDGVLTSVSGDSAQNLQQQEDLKQPITLSEEDAKKQLFNIYG
NDLTFIEEPEIKQVVYVDENTNKATNAYQITFSASTPEYVSGTVLIDAFGGNLLKELVQKLGIQVESSIVQSATSNKSTD
PSKLTGTGKDDLGINRTFGITQRSDGTYMLADYSRGKGIETYTANYKDYNNYRRNVWGYLDDLVTSNSTNFTDPKAVSAH
YLATKVYDFYQEKYGRNSFDNNGQKVISVVHGWNTNGTNKGNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRN
ESGLEYAGEAGAINEALSDILGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDHGGV
HTNSSIINKVAYLIASGGSHNGVNVHGIGEDKMFDIFYYANTDELNMTSDFKELKEACIRVATNLYGKDSLEVQAVQQAF
KAAYI

Specific function: Extracellular zinc metalloprotease [H]

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: =3.4.24.28 [H]

Molecular weight: Translated: 62483; Mature: 62483

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNFVKVGLTTGVVLSAIMPYGGVHAETEDLKVETKEDTFRTGNLTAPSQNSAENVAKDA
CCCEEEECHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEECCCCCCCCCCCHHHHHHHH
LKGKTEQALSSKQVNTESKVNYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDD
HCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEECCC
GVLTSVSGDSAQNLQQQEDLKQPITLSEEDAKKQLFNIYGNDLTFIEEPEIKQVVYVDEN
CEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECC
TNKATNAYQITFSASTPEYVSGTVLIDAFGGNLLKELVQKLGIQVESSIVQSATSNKSTD
CCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
PSKLTGTGKDDLGINRTFGITQRSDGTYMLADYSRGKGIETYTANYKDYNNYRRNVWGYL
CCCCCCCCCCCCCCCCEECCEECCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHH
DDLVTSNSTNFTDPKAVSAHYLATKVYDFYQEKYGRNSFDNNGQKVISVVHGWNTNGTNK
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC
GNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRNESGLEYAGEAGAINEALSDI
CCHHHHHHHHCCCEEEEECCCHHEEHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDHGGV
HHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCHHHHHCCCHHHHHCCCCCCCCCCCCCCC
HTNSSIINKVAYLIASGGSHNGVNVHGIGEDKMFDIFYYANTDELNMTSDFKELKEACIR
CCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
VATNLYGKDSLEVQAVQQAFKAAYI
HHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNFVKVGLTTGVVLSAIMPYGGVHAETEDLKVETKEDTFRTGNLTAPSQNSAENVAKDA
CCCEEEECHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEECCCCCCCCCCCHHHHHHHH
LKGKTEQALSSKQVNTESKVNYNVTQSRKSYDGTTLVRLQQTYEGRDVYGYQLTAHINDD
HCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCCCEEEEEEEEEEECCC
GVLTSVSGDSAQNLQQQEDLKQPITLSEEDAKKQLFNIYGNDLTFIEEPEIKQVVYVDEN
CEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECC
TNKATNAYQITFSASTPEYVSGTVLIDAFGGNLLKELVQKLGIQVESSIVQSATSNKSTD
CCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCC
PSKLTGTGKDDLGINRTFGITQRSDGTYMLADYSRGKGIETYTANYKDYNNYRRNVWGYL
CCCCCCCCCCCCCCCCEECCEECCCCCEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHH
DDLVTSNSTNFTDPKAVSAHYLATKVYDFYQEKYGRNSFDNNGQKVISVVHGWNTNGTNK
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCCCCC
GNPKQWFNAFSNGAMLVYGDPIVRAFDVAGHEFTHAVTRNESGLEYAGEAGAINEALSDI
CCHHHHHHHHCCCEEEEECCCHHEEHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
LGVAVEKYANNGKFNWTMGEQSGRIFRDMKNPSSISSRYPEDYRHYNNLPIDADHDHGGV
HHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCHHHHHCCCHHHHHCCCCCCCCCCCCCCC
HTNSSIINKVAYLIASGGSHNGVNVHGIGEDKMFDIFYYANTDELNMTSDFKELKEACIR
CCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHH
VATNLYGKDSLEVQAVQQAFKAAYI
HHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2290427; 2127074 [H]