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The map label for this gene is exp5 [H]

Identifier: 218231048

GI number: 218231048

Start: 406816

End: 408453

Strand: Direct

Name: exp5 [H]

Synonym: BCB4264_A0428

Alternate gene names: 218231048

Gene position: 406816-408453 (Clockwise)

Preceding gene: 218232682

Following gene: 218231797

Centisome position: 7.51

GC content: 37.48

Gene sequence:

>1638_bases
ATGAAAATTACGTCTTTTGATTTTTGGCAAAAGTTCGGGAAAGCGTTATTAGTTGTTGTAGCCGTAATGCCAGCAGCGGG
TTTAATGATTTCCATCGGTAAGTTAATTGGTATGTCTGCTGGGGATGTTAACGCAGTTCATACAATTGCTCGCGTAATGG
AAGACATCGGTTGGGCAATCATTACAAATCTACACATCTTATTCGCAGTAGCAATTGGGGGATCTTGGGCGAAGGATCGT
GCAGGTGGTGCATTTGCAGCGCTATTAGCATTCGTCTTAACAAACCGAATTACAGGAGCTATATTTGGCGTAAACGCTCA
AATGTTAGCGGATTCAAAAGCGACAGTTTCTTCAGTAATAGCAGGAGATTTACTTGTAAAAGATTACTTTACTTCTGTAC
TTGGTGCACCAGCATTAAACATGGGAGTTTTCGTGGGGATTATCACAGGTTTCTTAGGAGCTAATCTATATAACAAATAT
TATAACTATAATAAACTGCCACAGGCATTAGCATTCTTTAATGGAAAACGATTTGTACCATTCGTTGTAATTCTTTGGTC
TACAGTTACTGCGATTGTATTATCACTTCTATGGCCATTCATCCAAAGTGGGTTAAATGAATTTGGTCGCTGGATTGCAG
CTTCAAAAGATAGTGCACCAGTTGTTGCACCGTTTGTATATGGAACGTTAGAGCGTTTATTATTACCATTTGGTTTACAC
CATATGTTAACGATTCCGATGAACTATACAGAGCTAGGCGGAACATATACGATGCTAACTGGTTCAAAAGTTGGACAAGT
TGTAGCAGGACAAGATCCATTATGGCTTGCATGGATTACAGATTTAAATAATTTATTGGCAAATGGAGATACGAAGGCAT
ATAACGATTTATTAAATAACGTTGTACCAGCTCGTTTCAAAGCTGGACAAGTTATCGGCTCAACAGCAGCGTTAATGGGG
ATTGCATTTGCGATGTTCCGTAACGTTGATAAAGAAAAGCGTGCAAAATATAAACCAATGTTTTTATCAGCAGCATTAGC
AGTGTTCTTAACAGGTGTAACAGAACCAATTGAATTCATGTTCATGTTTATTGCTCCAGTATTATATGTTGTATATGCTA
TTACAACAGGACTTGCATTCGCGCTAGCTGATTTAATTAACTTACGTGTTCATGCATTTGGATTTATTGAGTTAATTACT
CGTACGCCAATGATGGTTAACGCAGGTTTAACAAGAGACTTAATCAACTTTGTTATTGTTTCATTAGTGTTCTTCGGTCT
TAACTTTACACTATTTAATTTCTTAATTAAAAAATTCAATTTACCAACACCAGGGCGTGCAGGTAACTATATTGATAATG
AAGATGAGGCATCAGAAGGAACAGGAAATGTACAAGACGGTTCATTAGCAACAAAAGTTATCGATTTATTAGGTGGAAAA
GAAAATATTGCTGACGTAGATGCTTGTATGACGCGCTTACGTGTAACAGTAAAAGATTTAGATGTTGTTGCACCAGAAGC
ACAGTGGAAACAAAATGGTGCTTTAGGGCTTATTGTAAAAGATAAAGGTGTACAAGCGGTATATGGTCCGAAAGCTGACG
TATTAAAGTCAGACATTCAAGATATGTTAGGTGCGTAA

Upstream 100 bases:

>100_bases
AAGATAAAAATAAAGTAATATAAGGAATCGTTTTCATAAAGGGAACAGAAATTATAATTTAAATCATTATGTTTTTATAA
ATAAAGGGGAGGAAGAACAG

Downstream 100 bases:

>100_bases
TAATATGAAATTGCTAACTTTAAACTGTCATTCTTGGCAAGAAGAGAATCAAATAGAAAAGATACAATACCTTGCTAAAG
TAATTCAAGAAGAAGAGTAC

Product: PTS system, IIBC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMSAGDVNAVHTIARVMEDIGWAIITNLHILFAVAIGGSWAKDR
AGGAFAALLAFVLTNRITGAIFGVNAQMLADSKATVSSVIAGDLLVKDYFTSVLGAPALNMGVFVGIITGFLGANLYNKY
YNYNKLPQALAFFNGKRFVPFVVILWSTVTAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVVAPFVYGTLERLLLPFGLH
HMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWITDLNNLLANGDTKAYNDLLNNVVPARFKAGQVIGSTAALMG
IAFAMFRNVDKEKRAKYKPMFLSAALAVFLTGVTEPIEFMFMFIAPVLYVVYAITTGLAFALADLINLRVHAFGFIELIT
RTPMMVNAGLTRDLINFVIVSLVFFGLNFTLFNFLIKKFNLPTPGRAGNYIDNEDEASEGTGNVQDGSLATKVIDLLGGK
ENIADVDACMTRLRVTVKDLDVVAPEAQWKQNGALGLIVKDKGVQAVYGPKADVLKSDIQDMLGA

Sequences:

>Translated_545_residues
MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMSAGDVNAVHTIARVMEDIGWAIITNLHILFAVAIGGSWAKDR
AGGAFAALLAFVLTNRITGAIFGVNAQMLADSKATVSSVIAGDLLVKDYFTSVLGAPALNMGVFVGIITGFLGANLYNKY
YNYNKLPQALAFFNGKRFVPFVVILWSTVTAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVVAPFVYGTLERLLLPFGLH
HMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWITDLNNLLANGDTKAYNDLLNNVVPARFKAGQVIGSTAALMG
IAFAMFRNVDKEKRAKYKPMFLSAALAVFLTGVTEPIEFMFMFIAPVLYVVYAITTGLAFALADLINLRVHAFGFIELIT
RTPMMVNAGLTRDLINFVIVSLVFFGLNFTLFNFLIKKFNLPTPGRAGNYIDNEDEASEGTGNVQDGSLATKVIDLLGGK
ENIADVDACMTRLRVTVKDLDVVAPEAQWKQNGALGLIVKDKGVQAVYGPKADVLKSDIQDMLGA
>Mature_545_residues
MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMSAGDVNAVHTIARVMEDIGWAIITNLHILFAVAIGGSWAKDR
AGGAFAALLAFVLTNRITGAIFGVNAQMLADSKATVSSVIAGDLLVKDYFTSVLGAPALNMGVFVGIITGFLGANLYNKY
YNYNKLPQALAFFNGKRFVPFVVILWSTVTAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVVAPFVYGTLERLLLPFGLH
HMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWITDLNNLLANGDTKAYNDLLNNVVPARFKAGQVIGSTAALMG
IAFAMFRNVDKEKRAKYKPMFLSAALAVFLTGVTEPIEFMFMFIAPVLYVVYAITTGLAFALADLINLRVHAFGFIELIT
RTPMMVNAGLTRDLINFVIVSLVFFGLNFTLFNFLIKKFNLPTPGRAGNYIDNEDEASEGTGNVQDGSLATKVIDLLGGK
ENIADVDACMTRLRVTVKDLDVVAPEAQWKQNGALGLIVKDKGVQAVYGPKADVLKSDIQDMLGA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=542, Percent_Identity=33.5793357933579, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1787908, Length=554, Percent_Identity=29.7833935018051, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1786894, Length=535, Percent_Identity=33.4579439252336, Blast_Score=204, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011300 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 58917; Mature: 58917

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITSFDFWQKFGKALLVVVAVMPAAGLMISIGKLIGMSAGDVNAVHTIARVMEDIGWAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ITNLHILFAVAIGGSWAKDRAGGAFAALLAFVLTNRITGAIFGVNAQMLADSKATVSSVI
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCHHHHCCCHHHHHHHH
AGDLLVKDYFTSVLGAPALNMGVFVGIITGFLGANLYNKYYNYNKLPQALAFFNGKRFVP
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHH
FVVILWSTVTAIVLSLLWPFIQSGLNEFGRWIAASKDSAPVVAPFVYGTLERLLLPFGLH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCH
HMLTIPMNYTELGGTYTMLTGSKVGQVVAGQDPLWLAWITDLNNLLANGDTKAYNDLLNN
HHEECCCCHHHCCCEEEEEECCHHCCCCCCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHC
VVPARFKAGQVIGSTAALMGIAFAMFRNVDKEKRAKYKPMFLSAALAVFLTGVTEPIEFM
CCCCHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
FMFIAPVLYVVYAITTGLAFALADLINLRVHAFGFIELITRTPMMVNAGLTRDLINFVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCHHHHHHHHHHH
SLVFFGLNFTLFNFLIKKFNLPTPGRAGNYIDNEDEASEGTGNVQDGSLATKVIDLLGGK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
ENIADVDACMTRLRVTVKDLDVVAPEAQWKQNGALGLIVKDKGVQAVYGPKADVLKSDIQ
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCCEEECCCHHHHHHHHH
DMLGA
HHHCC
>Mature Secondary Structure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HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11463916; 7934910 [H]