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The map label for this gene is glpR [C]

Identifier: 218231009

GI number: 218231009

Start: 1337417

End: 1338199

Strand: Direct

Name: glpR [C]

Synonym: BCB4264_A1380

Alternate gene names: 218231009

Gene position: 1337417-1338199 (Clockwise)

Preceding gene: 218234104

Following gene: 218234774

Centisome position: 24.68

GC content: 35.76

Gene sequence:

>783_bases
ATGTCTGTAGTAGGAGAAGAAAGAAAGCGAACCATTCTTGAAAAGGTAGAATTTAAAGGGAAAGTAAAGGTCTCAGAATT
AGCGAGAGAATTTGCTGTATCAACAGAAACGATTCGTCGATATTTAGAAGAATTAGATCGTGAAAAGAAGCTGAAAAAAG
TGTATGGTGGAGCTGTTCAACTTCCAGGCGCTGGAGTAGAGGCACCAATGTTAGAAAGAGAAATGCTACATATAGAAGAG
AAGAAAAGAATTGGTTATAAAGCAGCGACATTTGTAGAAGATGGTGATGTCATTGCAATTGATGATGGAAGTACACCGCT
TCAGATGGTTCCATACCTTGTTCATCGTAAGAACTTAACAATTGTAACAAGTTCATTTCCAGTCGCAACACAATTAATTT
CTTCTATTAATAAAAAGATGTTTCATGGTGAAGTTTTATTTATAGGTGGAAAAGTATCTCCAAAGCATTCGCGTGTATCA
GGGTCTATTTCTCAGCAAGTCATACAGCAATTCCATTTTCATAAAGCGTTTGTTTCGATTGATGGGTTATTACCTAGTTT
TGGAGTTTCCAGCTTTGAATTAGAGAAAGCGAAATTGTCAGAGGCGATGATGAAATTAGCTGAGAAAACATATATTTTAT
GTGATCATACGAAGGTAGGCGTGAAAGGGAATTATCGTATAGCAGCAATTTCGCGTATTCAACACGTAATTTGTGATAAA
AAAATGCCATATAGCTTTGAAGAAGAACTTATGAAGCATAATATTCAGTGGACAGTTTGTTAA

Upstream 100 bases:

>100_bases
CGCGGTATTCATATTCATGAAGAAGTTTCTACTTATAAAGAAAATTATAACTTTGTATAAGTAAGGAAGTTTATAAGGGA
GATATAAATGAGGTGAAGCT

Downstream 100 bases:

>100_bases
ATACAGTGAAAGCACATAAACTCCCACCTAATTTTTAGGAGGGAGTTTTATTATCTGTAAATCGTAAAATAAAAGATTTG
CAGTTATGCAAAAAGTGGAC

Product: transcriptional regulator, DeoR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSVVGEERKRTILEKVEFKGKVKVSELAREFAVSTETIRRYLEELDREKKLKKVYGGAVQLPGAGVEAPMLEREMLHIEE
KKRIGYKAATFVEDGDVIAIDDGSTPLQMVPYLVHRKNLTIVTSSFPVATQLISSINKKMFHGEVLFIGGKVSPKHSRVS
GSISQQVIQQFHFHKAFVSIDGLLPSFGVSSFELEKAKLSEAMMKLAEKTYILCDHTKVGVKGNYRIAAISRIQHVICDK
KMPYSFEEELMKHNIQWTVC

Sequences:

>Translated_260_residues
MSVVGEERKRTILEKVEFKGKVKVSELAREFAVSTETIRRYLEELDREKKLKKVYGGAVQLPGAGVEAPMLEREMLHIEE
KKRIGYKAATFVEDGDVIAIDDGSTPLQMVPYLVHRKNLTIVTSSFPVATQLISSINKKMFHGEVLFIGGKVSPKHSRVS
GSISQQVIQQFHFHKAFVSIDGLLPSFGVSSFELEKAKLSEAMMKLAEKTYILCDHTKVGVKGNYRIAAISRIQHVICDK
KMPYSFEEELMKHNIQWTVC
>Mature_259_residues
SVVGEERKRTILEKVEFKGKVKVSELAREFAVSTETIRRYLEELDREKKLKKVYGGAVQLPGAGVEAPMLEREMLHIEEK
KRIGYKAATFVEDGDVIAIDDGSTPLQMVPYLVHRKNLTIVTSSFPVATQLISSINKKMFHGEVLFIGGKVSPKHSRVSG
SISQQVIQQFHFHKAFVSIDGLLPSFGVSSFELEKAKLSEAMMKLAEKTYILCDHTKVGVKGNYRIAAISRIQHVICDKK
MPYSFEEELMKHNIQWTVC

Specific function: Repressor Of The Glycerol-3-Phosphate Regulon. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=254, Percent_Identity=29.5275590551181, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789059, Length=253, Percent_Identity=29.2490118577075, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787540, Length=239, Percent_Identity=32.6359832635983, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI226510968, Length=254, Percent_Identity=29.5275590551181, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=24.901185770751, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788069, Length=258, Percent_Identity=29.0697674418605, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082344, Length=257, Percent_Identity=24.124513618677, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790753, Length=176, Percent_Identity=23.2954545454545, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1787063, Length=240, Percent_Identity=25.4166666666667, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790635, Length=244, Percent_Identity=27.0491803278689, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789170, Length=237, Percent_Identity=24.4725738396624, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29360; Mature: 29228

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVGEERKRTILEKVEFKGKVKVSELAREFAVSTETIRRYLEELDREKKLKKVYGGAVQ
CCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEE
LPGAGVEAPMLEREMLHIEEKKRIGYKAATFVEDGDVIAIDDGSTPLQMVPYLVHRKNLT
CCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEEECCCEEEECCCCCHHHHHHHHHHCCCEE
IVTSSFPVATQLISSINKKMFHGEVLFIGGKVSPKHSRVSGSISQQVIQQFHFHKAFVSI
EEECCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHH
DGLLPSFGVSSFELEKAKLSEAMMKLAEKTYILCDHTKVGVKGNYRIAAISRIQHVICDK
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCEEECCCCCEEEHHHHHHHHHHHCC
KMPYSFEEELMKHNIQWTVC
CCCCCHHHHHHHCCCCEEEC
>Mature Secondary Structure 
SVVGEERKRTILEKVEFKGKVKVSELAREFAVSTETIRRYLEELDREKKLKKVYGGAVQ
CCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEE
LPGAGVEAPMLEREMLHIEEKKRIGYKAATFVEDGDVIAIDDGSTPLQMVPYLVHRKNLT
CCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEEECCCEEEECCCCCHHHHHHHHHHCCCEE
IVTSSFPVATQLISSINKKMFHGEVLFIGGKVSPKHSRVSGSISQQVIQQFHFHKAFVSI
EEECCCHHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHH
DGLLPSFGVSSFELEKAKLSEAMMKLAEKTYILCDHTKVGVKGNYRIAAISRIQHVICDK
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCEEECCCCCEEEHHHHHHHHHHHCC
KMPYSFEEELMKHNIQWTVC
CCCCCHHHHHHHCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]