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The map label for this gene is purQ [H]

Identifier: 218231005

GI number: 218231005

Start: 312972

End: 313655

Strand: Direct

Name: purQ [H]

Synonym: BCB4264_A0339

Alternate gene names: 218231005

Gene position: 312972-313655 (Clockwise)

Preceding gene: 218232164

Following gene: 218234715

Centisome position: 5.78

GC content: 38.3

Gene sequence:

>684_bases
GTGAAATTTGCCGTAATAGTATTTCCGGGTTCGAACTGTGATGTCGATATGTTCCATGCAATTAAAGATGAGCTTGGCGA
AGAAGTAGATTACGTTTGGCACGATACAGAGAATTTAGATGAATATGATGCAATTCTACTACCAGGTGGATTTTCTTATG
GTGACTACTTACGCTGCGGTGCTATCTCTCGCTTTGCTAATGCAATGAAAGCAGTGCAAAAAGCTGCTGAGCAAGGAAAG
CCGATTTTAGGTGTATGTAATGGATTCCAGATTCTTGTTGAATCAGGATTACTACCAGGAGCGTTAATAAGAAACGAAAA
CTTAAAATTTATGTGTCGCACTGTTCAGTTACGTGTTGAAAATAATGAAACGATGTTTACATCACAATATGAAAAAGATG
AAATAATTAATATTCCAATCGCGCATGGTGAGGGGAATTACTATTGTGATGAAGCGACTCTTAAACAATTAGAAGAGAAC
AATCAAATCGCATTCCGTTACGTAGAAAACCCTAACGGTAGCGTTTCAGATATTGCTGGTATTGTAAATGAAAAAGGAAA
TGTACTTGGTATGATGCCGCACCCAGAGCGTGCTGTAGATGAATTACTTGGCGGTGCTGAAGGGTTAAAAGTCTTTCAAT
CTATCTTAAAACAGTGGAGGGAAACATATGTCGTTAATGCTTGA

Upstream 100 bases:

>100_bases
TATCTGATTTAGATAGCAAGGTAAAAGAAATGTGTGAAAAACTATTAGCGAACGTTGTAATGGAAGACTTCCGTTATGAA
GTTGAGGAGGTTGTCGCACA

Downstream 100 bases:

>100_bases
ACCAAATCCAACACAAATTAAAGAAGAGCGTATATATGCGGAAATGGGGCTAACAGACGAAGAGTTTGCCATGGTTGAAA
AGATTTTAGGTCGTCTGCCA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGALIRNENLKFMCRTVQLRVENNETMFTSQYEKDEIINIPIAHGEGNYYCDEATLKQLEEN
NQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA

Sequences:

>Translated_227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGALIRNENLKFMCRTVQLRVENNETMFTSQYEKDEIINIPIAHGEGNYYCDEATLKQLEEN
NQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
>Mature_227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGALIRNENLKFMCRTVQLRVENNETMFTSQYEKDEIINIPIAHGEGNYYCDEATLKQLEEN
NQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=246, Percent_Identity=30.0813008130081, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17553022, Length=235, Percent_Identity=26.3829787234043, Blast_Score=74, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=243, Percent_Identity=29.2181069958848, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582111, Length=230, Percent_Identity=29.1304347826087, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24582109, Length=230, Percent_Identity=29.1304347826087, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI17137292, Length=230, Percent_Identity=29.1304347826087, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25349; Mature: 25349

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCHHCEEECCCCCCCCCCEEEECCCCCCCCHHHHH
AISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALIRNENLKFMCRTVQLRVE
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCCEEECCCCEEEEEEEEEEEC
NNETMFTSQYEKDEIINIPIAHGEGNYYCDEATLKQLEENNQIAFRYVENPNGSVSDIAG
CCCEEEECCCCCCCEEEEEEEECCCCEEECHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
IVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
HHCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCHHCEEECCCCCCCCCCEEEECCCCCCCCHHHHH
AISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALIRNENLKFMCRTVQLRVE
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCCEEECCCCEEEEEEEEEEEC
NNETMFTSQYEKDEIINIPIAHGEGNYYCDEATLKQLEENNQIAFRYVENPNGSVSDIAG
CCCEEEECCCCCCCEEEEEEEECCCCEEECHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
IVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
HHCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA