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The map label for this gene is citT [H]

Identifier: 218230963

GI number: 218230963

Start: 576688

End: 577380

Strand: Direct

Name: citT [H]

Synonym: BCB4264_A0596

Alternate gene names: 218230963

Gene position: 576688-577380 (Clockwise)

Preceding gene: 218233196

Following gene: 218235906

Centisome position: 10.64

GC content: 38.53

Gene sequence:

>693_bases
ATGAGTGAGGAGATTGAAGTATTAATTGTAGAAGATGATATTCGGATTGCTGACATTCATCGTCGTTTTACTGAAAAAAT
TGAGGGATTTAAAGTAATTGGAACGGCAACGACTGGAGAACAAGCGAAAGAATGGCTAGAGCTTGTGAAGCCACAGCTTG
TTTTATTAGATGTGTACTTACCTGATATGCAAGGAACGGAACTTGTCACATATATTAGGCATCATTTGCACGATACAGAT
ATTATTATGATTACAGCGGCATCGGAAACAGATGTAGTGAGGCACGCCCTGCGGGGCGGAGTAACAGATTATATCGTAAA
GCCACTAATGTTTGACCGGTTTAAAGCAAGTCTGGAAGGCTATCAAAAAAAGATTATACAGTTAAAGAAAAATAATCAAT
TATCTACGGAGCAAATTGAATATTTATGGTCTCAAAGAGGGGTGAAGGGAGATCAAATAGAATATGCCCCGAAAGGGATA
GATCCTTTAACTTTAGCGAAAATAAAAAAGCATATGTTAACAGTTAATGAAGAAGGGATTACAGCAGAGGTGCTAAGTTC
AATGGTAGGCGTAAGCCGATCAACTGCAAGGCGTTATTTAGAGTATTTGATATCTGGGAAGAAAGTCCACGCAGAGCTAA
TATATGGAAGTGTTGGGAGACCGGAGAGACGTTATTTTCTTGTTTCTTCATAA

Upstream 100 bases:

>100_bases
AGTTAGTAGAAGATTTAAATGGAAGTATTGCAATTGAAAAAGGGGATTTAGGTGGTGCGTTATTTATTATTGCACTACCG
AAAGAGAGAGGCGAATAGTA

Downstream 100 bases:

>100_bases
TAAAAAACAGTAGAGGATTTTATTCCTTCTACTGTTTTTTTTTGCATCTTATATTGGAATAATCCCAATTACAATTCCGG
TAATTAACATAACCATTGTC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLELVKPQLVLLDVYLPDMQGTELVTYIRHHLHDTD
IIMITAASETDVVRHALRGGVTDYIVKPLMFDRFKASLEGYQKKIIQLKKNNQLSTEQIEYLWSQRGVKGDQIEYAPKGI
DPLTLAKIKKHMLTVNEEGITAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLVSS

Sequences:

>Translated_230_residues
MSEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLELVKPQLVLLDVYLPDMQGTELVTYIRHHLHDTD
IIMITAASETDVVRHALRGGVTDYIVKPLMFDRFKASLEGYQKKIIQLKKNNQLSTEQIEYLWSQRGVKGDQIEYAPKGI
DPLTLAKIKKHMLTVNEEGITAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLVSS
>Mature_229_residues
SEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLELVKPQLVLLDVYLPDMQGTELVTYIRHHLHDTDI
IMITAASETDVVRHALRGGVTDYIVKPLMFDRFKASLEGYQKKIIQLKKNNQLSTEQIEYLWSQRGVKGDQIEYAPKGID
PLTLAKIKKHMLTVNEEGITAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLVSS

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=229, Percent_Identity=37.117903930131, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1790566, Length=223, Percent_Identity=30.0448430493274, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1788222, Length=103, Percent_Identity=33.0097087378641, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26262; Mature: 26131

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLELVKPQLVLLDVYL
CCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEC
PDMQGTELVTYIRHHLHDTDIIMITAASETDVVRHALRGGVTDYIVKPLMFDRFKASLEG
CCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YQKKIIQLKKNNQLSTEQIEYLWSQRGVKGDQIEYAPKGIDPLTLAKIKKHMLTVNEEGI
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCC
TAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLVSS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECC
>Mature Secondary Structure 
SEEIEVLIVEDDIRIADIHRRFTEKIEGFKVIGTATTGEQAKEWLELVKPQLVLLDVYL
CCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEC
PDMQGTELVTYIRHHLHDTDIIMITAASETDVVRHALRGGVTDYIVKPLMFDRFKASLEG
CCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YQKKIIQLKKNNQLSTEQIEYLWSQRGVKGDQIEYAPKGIDPLTLAKIKKHMLTVNEEGI
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCC
TAEVLSSMVGVSRSTARRYLEYLISGKKVHAELIYGSVGRPERRYFLVSS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]