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The map label for this gene is fabD [H]

Identifier: 218230903

GI number: 218230903

Start: 3871735

End: 3872679

Strand: Reverse

Name: fabD [H]

Synonym: BCB4264_A3951

Alternate gene names: 218230903

Gene position: 3872679-3871735 (Counterclockwise)

Preceding gene: 218231456

Following gene: 218233933

Centisome position: 71.46

GC content: 39.47

Gene sequence:

>945_bases
ATGGGAAAAATAGCATTTCTTTTTCCGGGCCAAGGTTCACAGGCAGTTGGAATGGGTAAACAATTAGCAGAGAATAATAA
AGAGGTTGCAAAAGTGTTTGCAAAAGCAGATGAGGTGTTGGAAGATTCACTTTCAGAAGTGATTTTTGAAGGACCGCAGG
AAAAGCTTACATTAACAACAAATGCGCAGCCTGCATTATTAACAACGAGTTTTGCTATTTTGACAGCTTTGAAAGAGTAT
GACATTACACCTGACTTTGTCGCTGGTCATAGTTTAGGTGAATATAGTGCTCTTGTAGCAGCTGGTGCATTAACTTTTGA
AGATGCTGTATATGCTGTAAGGAAACGTGGCGAATATATGGAAGAAGCTGTTCCGGGCGGGGAAGGCGCAATGGCAGCTA
TATTAGGTGCTGACCCACATATGCTGAAACAAGTTACAGAAGAAGTAACAAGTGAAGGATATGCAGTGCAAATCGCTAAT
ATGAATAGTACCAAGCAAATTGTGATTTCTGGAACGAAGCAAGGCGTAGAGGTTGCTTCTCAAAGAGCGAAAGAAAATGG
TGCAAAGAGAGCGATTCCACTAAAAGTAAGTGGGCCATTCCATTCTTCACTTATGAAGCCGGCAGCTGAGAAGTTCCAAA
GTGTTTTAAATGAAATTACAATTCATGACACGAATATTCCTGTTATTGCAAATGTTACGGCGGAAGTTATTACACGTGGT
GCAGACATTCAAGAAAAGTTAATTGAACAGCTTTATTCGCCTGTATTATGGTACCCGTCTATTGAATATATGGTGAGCCA
GGGAGTAGATACGTTTATTGAAATTGGACCTGGAAAAGTACTTGCTGGACTTATGAAGTCAATTGATTCATCAGTAAAAG
CATATGCGATATACGATGAAGAGACATTAAAAGATACCATTTCAAATTTGAGAGGAGAAAACTGA

Upstream 100 bases:

>100_bases
GTGCGATTCGTCAAACGAGAGAAATGGTAGCGAAAGAAGTAATTCCTACGATTTCAAGCGTAATGGAGAAAGAGTCACTC
CAATAAGAGGAGGATTTGAA

Downstream 100 bases:

>100_bases
TGTTAAAAGGGAAGGTAGCATTAGTAACTGGCGCTTCACGTGGAATTGGTCGCGCGATTGCGATCGATTTAGCGAAACAA
GGGGCAAATGTAGTAGTAAA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MGKIAFLFPGQGSQAVGMGKQLAENNKEVAKVFAKADEVLEDSLSEVIFEGPQEKLTLTTNAQPALLTTSFAILTALKEY
DITPDFVAGHSLGEYSALVAAGALTFEDAVYAVRKRGEYMEEAVPGGEGAMAAILGADPHMLKQVTEEVTSEGYAVQIAN
MNSTKQIVISGTKQGVEVASQRAKENGAKRAIPLKVSGPFHSSLMKPAAEKFQSVLNEITIHDTNIPVIANVTAEVITRG
ADIQEKLIEQLYSPVLWYPSIEYMVSQGVDTFIEIGPGKVLAGLMKSIDSSVKAYAIYDEETLKDTISNLRGEN

Sequences:

>Translated_314_residues
MGKIAFLFPGQGSQAVGMGKQLAENNKEVAKVFAKADEVLEDSLSEVIFEGPQEKLTLTTNAQPALLTTSFAILTALKEY
DITPDFVAGHSLGEYSALVAAGALTFEDAVYAVRKRGEYMEEAVPGGEGAMAAILGADPHMLKQVTEEVTSEGYAVQIAN
MNSTKQIVISGTKQGVEVASQRAKENGAKRAIPLKVSGPFHSSLMKPAAEKFQSVLNEITIHDTNIPVIANVTAEVITRG
ADIQEKLIEQLYSPVLWYPSIEYMVSQGVDTFIEIGPGKVLAGLMKSIDSSVKAYAIYDEETLKDTISNLRGEN
>Mature_313_residues
GKIAFLFPGQGSQAVGMGKQLAENNKEVAKVFAKADEVLEDSLSEVIFEGPQEKLTLTTNAQPALLTTSFAILTALKEYD
ITPDFVAGHSLGEYSALVAAGALTFEDAVYAVRKRGEYMEEAVPGGEGAMAAILGADPHMLKQVTEEVTSEGYAVQIANM
NSTKQIVISGTKQGVEVASQRAKENGAKRAIPLKVSGPFHSSLMKPAAEKFQSVLNEITIHDTNIPVIANVTAEVITRGA
DIQEKLIEQLYSPVLWYPSIEYMVSQGVDTFIEIGPGKVLAGLMKSIDSSVKAYAIYDEETLKDTISNLRGEN

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=312, Percent_Identity=32.3717948717949, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=42.2018348623853, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1787334, Length=298, Percent_Identity=47.3154362416107, Blast_Score=240, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=30.5084745762712, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=29.5918367346939, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=35.5481727574751, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33734; Mature: 33603

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKIAFLFPGQGSQAVGMGKQLAENNKEVAKVFAKADEVLEDSLSEVIFEGPQEKLTLTT
CCEEEEEECCCCCCHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
NAQPALLTTSFAILTALKEYDITPDFVAGHSLGEYSALVAAGALTFEDAVYAVRKRGEYM
CCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEAVPGGEGAMAAILGADPHMLKQVTEEVTSEGYAVQIANMNSTKQIVISGTKQGVEVAS
HHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCHHHHHHHH
QRAKENGAKRAIPLKVSGPFHSSLMKPAAEKFQSVLNEITIHDTNIPVIANVTAEVITRG
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHHHCC
ADIQEKLIEQLYSPVLWYPSIEYMVSQGVDTFIEIGPGKVLAGLMKSIDSSVKAYAIYDE
CCHHHHHHHHHHCCEECCCCHHHHHHCCCHHEEECCCHHHHHHHHHHHCCCCEEEEEECH
ETLKDTISNLRGEN
HHHHHHHHHHCCCC
>Mature Secondary Structure 
GKIAFLFPGQGSQAVGMGKQLAENNKEVAKVFAKADEVLEDSLSEVIFEGPQEKLTLTT
CEEEEEECCCCCCHHHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
NAQPALLTTSFAILTALKEYDITPDFVAGHSLGEYSALVAAGALTFEDAVYAVRKRGEYM
CCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEAVPGGEGAMAAILGADPHMLKQVTEEVTSEGYAVQIANMNSTKQIVISGTKQGVEVAS
HHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCHHHHHHHH
QRAKENGAKRAIPLKVSGPFHSSLMKPAAEKFQSVLNEITIHDTNIPVIANVTAEVITRG
HHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEHHHHHHHHCC
ADIQEKLIEQLYSPVLWYPSIEYMVSQGVDTFIEIGPGKVLAGLMKSIDSSVKAYAIYDE
CCHHHHHHHHHHCCEECCCCHHHHHHCCCHHEEECCCHHHHHHHHHHHCCCCEEEEEECH
ETLKDTISNLRGEN
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]