Click here to switch to the map view.

The map label for this gene is glmS [H]

Identifier: 213692877

GI number: 213692877

Start: 2204649

End: 2206541

Strand: Reverse

Name: glmS [H]

Synonym: Blon_2018

Alternate gene names: 213692877

Gene position: 2206541-2204649 (Counterclockwise)

Preceding gene: 213692878

Following gene: 213692876

Centisome position: 77.89

GC content: 62.49

Gene sequence:

>1893_bases
ATGTGTGGAATCGTTGGATACGCGGGAAATATTGAAACGGCATGCGGTAGGCCTTTGGAGGTCTGCCTGCAAGGCCTGGA
ACGTCTGGAATACCGAGGCTATGACTCGGCCGGTGTGGCGCTGACCGCGCCCGGCATGGATAAGGTGGTCGTGCGCAAGA
AGGCCGGCCGTTTGAAGAACCTGGTCGAAGACATCGAGCGTAAGCCGATGCCGCTTGCCACGGTGGGCATCGGCCACACG
CGCTGGGCCACCAATGGCGAGCCGAGCGACGTGAACGCCCACCCGCACACCAGCATGGACGGCAAGGTGGCCATCATCCA
TAACGGCATCATCGAAAACGCCTCTCAGCTGCGTCTCGACCTGCAAGCCGAAGGCTACCGATTTGCTTCTGCCACCGACA
CTGAGGTGGCCGCTAAGCTGCTCGGCAAGATCGTGGACAAGATTATCGCGGATGAAGGCAAGCCAGACCTGTTCAAGGCT
GTGCGCCGCATGGCCCGCATGCTTGAAGGCGCGTTCACCATTCTGGCCACCGACTGCCGCCAGCCGGGCATCGTGGTCGG
AGCCCGCCATGATTCGCCGCTGGTCGTGGGCCTTGGCGAGGGGGAGAACTTCCTCGGTTCCGACGTGGCCGCATTCGTGG
CCTACACCAAGCGCGCCATGGAAGTCGACCAGGATCAGGCCGTATGCGTGTCCGCCGACAAGGTCATCGTCACCGATTTC
AACGGCAACGTGGTCGAAAACCCGAAGACCTACACCGTGGATTGGGACGCCTCGGCCGCCGAAAAGGGCGGCTGGGATTC
CTTTATGGACAAGGAGATCCACGAAGACCCTGCCGCAGTGCAGCGCACCCTGCTTGGCCGCTTCGATACGAATGGCGGCA
TCACCCTTGATGAAGTGCGTATCGACGAACACGACTTCAAGGCCATCGACAAAATCATCGTTGTGGCCTGCGGCACCGCC
AGCTACGCCGGCCAGGTAGCCAAATACGCCATCGAACACTGGGTGCGTATCCCCGTGGAAATCGAACTCGCGCACGAATT
CCGTTACCGTGACCCGATTCTGACCCCGCGTACGCTCGTGGTGGCCATTTCTCAGTCCGGCGAAACCATGGATACGCTGA
TGGCCCTGCGCCACGCGCGCGAACAGGGGTCCAAGGTGCTGGCCATCTGCAACACGCAGGGTGCCTCCATTCCGCGTGAA
TCCGACGCCGTGCTCTACACACACGCCGGCCCGGAAGTTGCCGTGGCATCCACCAAGGCGTTCGTGGCGCAGATCACCGC
CGCCTACCTGCTGGGCCTGTATCTGGCGCAGGTCAAGGGCGCGATGTTCCGCGATGAGATTCATCAGGTGCTCGACTCCC
TGAAAGATATGCCGCGCAAGATTCAGTGGGTGCTCGACACCCAGCCCAAGACCATCCAGGCGGCCGCCGAGCGCATGGTG
AACGCCAACTCCTTCTTGTTCCTCGGCCGCCACGTGGGCTACCCGGTGGCGCTTGAGGGCGCGTTGAAGCTCAAGGAAAT
CGCCTACACCTTCACCGAAGGCTTCGCGGCCGGCGAGCTCAAGCATGGACCGATCGCGCTGGTGGACGAGGGTGAGCCGG
TGGTGTTCATCGTGCCGCCGCAGCGCGGCCGCAATGTGTTGCACGCCAAGGTGATCTCCGGTATCGAGGAGGTCAAGGCT
CGTGGCGCGTACATCATCGCCGTGGCCGAGCAGGGCGACCCGGATGTGGAACGGTACGCTGACGTGGTGTTCTGGCGCCC
CGCCTGCCCAACGCTGATGAGCCCGCTGGTTGACGTGGTGCCGCTGCAGCTGTTCGCCATGGACATGGCAAAGCTCAAGG
GCTACGACGTGGACAAGCCCCGCAACCTCGCCAAGTCCGTGACCGTTGAGTAA

Upstream 100 bases:

>100_bases
GGACACGCCGGGTGGTTCGCCCGCGCCGCATGCTCCGATCGCGCGAATACGGCGGGTTGGATTCGCTTTGCGCAATAATC
GTCCGCTAGGCTGGTGAGCC

Downstream 100 bases:

>100_bases
GCCACATCGGTATGTGATTGACGAGCCTCATATTCCGTTTGAGATGGACGTGCTGTATGAGGACGAGCGGATCATCGTGG
TGGACAAGCCGCATTTTCTG

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MCGIVGYAGNIETACGRPLEVCLQGLERLEYRGYDSAGVALTAPGMDKVVVRKKAGRLKNLVEDIERKPMPLATVGIGHT
RWATNGEPSDVNAHPHTSMDGKVAIIHNGIIENASQLRLDLQAEGYRFASATDTEVAAKLLGKIVDKIIADEGKPDLFKA
VRRMARMLEGAFTILATDCRQPGIVVGARHDSPLVVGLGEGENFLGSDVAAFVAYTKRAMEVDQDQAVCVSADKVIVTDF
NGNVVENPKTYTVDWDASAAEKGGWDSFMDKEIHEDPAAVQRTLLGRFDTNGGITLDEVRIDEHDFKAIDKIIVVACGTA
SYAGQVAKYAIEHWVRIPVEIELAHEFRYRDPILTPRTLVVAISQSGETMDTLMALRHAREQGSKVLAICNTQGASIPRE
SDAVLYTHAGPEVAVASTKAFVAQITAAYLLGLYLAQVKGAMFRDEIHQVLDSLKDMPRKIQWVLDTQPKTIQAAAERMV
NANSFLFLGRHVGYPVALEGALKLKEIAYTFTEGFAAGELKHGPIALVDEGEPVVFIVPPQRGRNVLHAKVISGIEEVKA
RGAYIIAVAEQGDPDVERYADVVFWRPACPTLMSPLVDVVPLQLFAMDMAKLKGYDVDKPRNLAKSVTVE

Sequences:

>Translated_630_residues
MCGIVGYAGNIETACGRPLEVCLQGLERLEYRGYDSAGVALTAPGMDKVVVRKKAGRLKNLVEDIERKPMPLATVGIGHT
RWATNGEPSDVNAHPHTSMDGKVAIIHNGIIENASQLRLDLQAEGYRFASATDTEVAAKLLGKIVDKIIADEGKPDLFKA
VRRMARMLEGAFTILATDCRQPGIVVGARHDSPLVVGLGEGENFLGSDVAAFVAYTKRAMEVDQDQAVCVSADKVIVTDF
NGNVVENPKTYTVDWDASAAEKGGWDSFMDKEIHEDPAAVQRTLLGRFDTNGGITLDEVRIDEHDFKAIDKIIVVACGTA
SYAGQVAKYAIEHWVRIPVEIELAHEFRYRDPILTPRTLVVAISQSGETMDTLMALRHAREQGSKVLAICNTQGASIPRE
SDAVLYTHAGPEVAVASTKAFVAQITAAYLLGLYLAQVKGAMFRDEIHQVLDSLKDMPRKIQWVLDTQPKTIQAAAERMV
NANSFLFLGRHVGYPVALEGALKLKEIAYTFTEGFAAGELKHGPIALVDEGEPVVFIVPPQRGRNVLHAKVISGIEEVKA
RGAYIIAVAEQGDPDVERYADVVFWRPACPTLMSPLVDVVPLQLFAMDMAKLKGYDVDKPRNLAKSVTVE
>Mature_630_residues
MCGIVGYAGNIETACGRPLEVCLQGLERLEYRGYDSAGVALTAPGMDKVVVRKKAGRLKNLVEDIERKPMPLATVGIGHT
RWATNGEPSDVNAHPHTSMDGKVAIIHNGIIENASQLRLDLQAEGYRFASATDTEVAAKLLGKIVDKIIADEGKPDLFKA
VRRMARMLEGAFTILATDCRQPGIVVGARHDSPLVVGLGEGENFLGSDVAAFVAYTKRAMEVDQDQAVCVSADKVIVTDF
NGNVVENPKTYTVDWDASAAEKGGWDSFMDKEIHEDPAAVQRTLLGRFDTNGGITLDEVRIDEHDFKAIDKIIVVACGTA
SYAGQVAKYAIEHWVRIPVEIELAHEFRYRDPILTPRTLVVAISQSGETMDTLMALRHAREQGSKVLAICNTQGASIPRE
SDAVLYTHAGPEVAVASTKAFVAQITAAYLLGLYLAQVKGAMFRDEIHQVLDSLKDMPRKIQWVLDTQPKTIQAAAERMV
NANSFLFLGRHVGYPVALEGALKLKEIAYTFTEGFAAGELKHGPIALVDEGEPVVFIVPPQRGRNVLHAKVISGIEEVKA
RGAYIIAVAEQGDPDVERYADVVFWRPACPTLMSPLVDVVPLQLFAMDMAKLKGYDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=692, Percent_Identity=33.6705202312139, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI205277386, Length=694, Percent_Identity=34.149855907781, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI29570798, Length=179, Percent_Identity=27.3743016759777, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790167, Length=633, Percent_Identity=42.4960505529226, Blast_Score=444, Evalue=1e-126,
Organism=Escherichia coli, GI1788651, Length=179, Percent_Identity=28.4916201117318, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532899, Length=435, Percent_Identity=33.5632183908046, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17532897, Length=435, Percent_Identity=33.5632183908046, Blast_Score=246, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17539970, Length=435, Percent_Identity=33.3333333333333, Blast_Score=245, Evalue=6e-65,
Organism=Saccharomyces cerevisiae, GI6322745, Length=436, Percent_Identity=34.1743119266055, Blast_Score=237, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6323731, Length=446, Percent_Identity=27.3542600896861, Blast_Score=171, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=36.5853658536585, Blast_Score=131, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21357745, Length=695, Percent_Identity=33.3812949640288, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI28573187, Length=146, Percent_Identity=34.2465753424658, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 68611; Mature: 68611

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00443 GATASE_TYPE_II ; PS00283 SOYBEAN_KUNITZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGYAGNIETACGRPLEVCLQGLERLEYRGYDSAGVALTAPGMDKVVVRKKAGRLKN
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHH
LVEDIERKPMPLATVGIGHTRWATNGEPSDVNAHPHTSMDGKVAIIHNGIIENASQLRLD
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHCCCHHEEEE
LQAEGYRFASATDTEVAAKLLGKIVDKIIADEGKPDLFKAVRRMARMLEGAFTILATDCR
EECCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCC
QPGIVVGARHDSPLVVGLGEGENFLGSDVAAFVAYTKRAMEVDQDQAVCVSADKVIVTDF
CCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEC
NGNVVENPKTYTVDWDASAAEKGGWDSFMDKEIHEDPAAVQRTLLGRFDTNGGITLDEVR
CCCEECCCEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEE
IDEHDFKAIDKIIVVACGTASYAGQVAKYAIEHWVRIPVEIELAHEFRYRDPILTPRTLV
ECCHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHEECCEEEEEEHHHHCCCCCCCCCEEE
VAISQSGETMDTLMALRHAREQGSKVLAICNTQGASIPRESDAVLYTHAGPEVAVASTKA
EEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEECCCCEEEHHHHH
FVAQITAAYLLGLYLAQVKGAMFRDEIHQVLDSLKDMPRKIQWVLDTQPKTIQAAAERMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHC
NANSFLFLGRHVGYPVALEGALKLKEIAYTFTEGFAAGELKHGPIALVDEGEPVVFIVPP
CCCCEEEEECCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEECC
QRGRNVLHAKVISGIEEVKARGAYIIAVAEQGDPDVERYADVVFWRPACPTLMSPLVDVV
CCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHEEEECCCCHHHHHHHHHHH
PLQLFAMDMAKLKGYDVDKPRNLAKSVTVE
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MCGIVGYAGNIETACGRPLEVCLQGLERLEYRGYDSAGVALTAPGMDKVVVRKKAGRLKN
CCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHH
LVEDIERKPMPLATVGIGHTRWATNGEPSDVNAHPHTSMDGKVAIIHNGIIENASQLRLD
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHCCCHHEEEE
LQAEGYRFASATDTEVAAKLLGKIVDKIIADEGKPDLFKAVRRMARMLEGAFTILATDCR
EECCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEEECCC
QPGIVVGARHDSPLVVGLGEGENFLGSDVAAFVAYTKRAMEVDQDQAVCVSADKVIVTDF
CCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEC
NGNVVENPKTYTVDWDASAAEKGGWDSFMDKEIHEDPAAVQRTLLGRFDTNGGITLDEVR
CCCEECCCEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEEEEE
IDEHDFKAIDKIIVVACGTASYAGQVAKYAIEHWVRIPVEIELAHEFRYRDPILTPRTLV
ECCHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHEECCEEEEEEHHHHCCCCCCCCCEEE
VAISQSGETMDTLMALRHAREQGSKVLAICNTQGASIPRESDAVLYTHAGPEVAVASTKA
EEEECCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEEEEECCCCEEEHHHHH
FVAQITAAYLLGLYLAQVKGAMFRDEIHQVLDSLKDMPRKIQWVLDTQPKTIQAAAERMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHC
NANSFLFLGRHVGYPVALEGALKLKEIAYTFTEGFAAGELKHGPIALVDEGEPVVFIVPP
CCCCEEEEECCCCCCEEECCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEEECC
QRGRNVLHAKVISGIEEVKARGAYIIAVAEQGDPDVERYADVVFWRPACPTLMSPLVDVV
CCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHEEEECCCCHHHHHHHHHHH
PLQLFAMDMAKLKGYDVDKPRNLAKSVTVE
HHHHHHHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 14602910 [H]