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The map label for this gene is luxS [H]

Identifier: 213692859

GI number: 213692859

Start: 2182881

End: 2183375

Strand: Reverse

Name: luxS [H]

Synonym: Blon_2000

Alternate gene names: 213692859

Gene position: 2183375-2182881 (Counterclockwise)

Preceding gene: 213692860

Following gene: 213692858

Centisome position: 77.08

GC content: 60.61

Gene sequence:

>495_bases
ATGACAGAAGGCAAGGCCGAAAAGCCCGTCGTCGAATCATTCCAGCTTGATCACACCAAGGTCAAGGCACCGTACGTGCG
TTACATCGACACCGAAACGGGCCCTCACGGCGACGTGATCTCCAATTACGATCTGCGCCTGACCCAGCCGAACAAGCAGG
CCATCCCCACCGGCGGCCTGCACACCATCGAACACACCATCGCCGTGCTGCTGCGCGAACGTATCCCGGGCTACATCGAC
TGCTCGCCGTTCGGCTGCCGCACCGGTTTCCACCTGCTGACCTGGGGCACCCACTCCACCGAGGATGTGGCCAAGGCGTT
GAAGGAATCGTTGGAGTTCATCGCATACAAGGCCACGTGGGATGACGTGCCCGCCACCACTGAGAAGAGCTGCGGCAACT
ATCGCGACCACAGCCTGTTCGCCGCCAAGGAATGGGCCAAGCAGATCCTTGAGGAAGGCATCAGTTCCGACCCGTTCGAA
CGCAAGGTCGTCTGA

Upstream 100 bases:

>100_bases
GCGAACCGCGGAGTATTTGCGGGCGTTCTTGGGCTGGCGCGACTACGATGACTGTTCGATACTTCATGACCGAACAGTCA
GCAAGTAGAAAGGCAACAGC

Downstream 100 bases:

>100_bases
TTCGTCTGATTCGATCCAATTCTGATTCGGCTCCCGCTGGCGGGAGCTGGGGGCAAAGCCAACTGAGGGTGGCTGTCCTC
AACTCGGCTGGACTGTCCGG

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTEGKAEKPVVESFQLDHTKVKAPYVRYIDTETGPHGDVISNYDLRLTQPNKQAIPTGGLHTIEHTIAVLLRERIPGYID
CSPFGCRTGFHLLTWGTHSTEDVAKALKESLEFIAYKATWDDVPATTEKSCGNYRDHSLFAAKEWAKQILEEGISSDPFE
RKVV

Sequences:

>Translated_164_residues
MTEGKAEKPVVESFQLDHTKVKAPYVRYIDTETGPHGDVISNYDLRLTQPNKQAIPTGGLHTIEHTIAVLLRERIPGYID
CSPFGCRTGFHLLTWGTHSTEDVAKALKESLEFIAYKATWDDVPATTEKSCGNYRDHSLFAAKEWAKQILEEGISSDPFE
RKVV
>Mature_163_residues
TEGKAEKPVVESFQLDHTKVKAPYVRYIDTETGPHGDVISNYDLRLTQPNKQAIPTGGLHTIEHTIAVLLRERIPGYIDC
SPFGCRTGFHLLTWGTHSTEDVAKALKESLEFIAYKATWDDVPATTEKSCGNYRDHSLFAAKEWAKQILEEGISSDPFER
KVV

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=150, Percent_Identity=40, Blast_Score=124, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 18420; Mature: 18289

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGKAEKPVVESFQLDHTKVKAPYVRYIDTETGPHGDVISNYDLRLTQPNKQAIPTGGL
CCCCCCCCCHHHHHCCCCCEECCCEEEEEECCCCCCCCEECCCCEEEECCCCCCCCCCCH
HTIEHTIAVLLRERIPGYIDCSPFGCRTGFHLLTWGTHSTEDVAKALKESLEFIAYKATW
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHEEEECCC
DDVPATTEKSCGNYRDHSLFAAKEWAKQILEEGISSDPFERKVV
CCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TEGKAEKPVVESFQLDHTKVKAPYVRYIDTETGPHGDVISNYDLRLTQPNKQAIPTGGL
CCCCCCCCHHHHHCCCCCEECCCEEEEEECCCCCCCCEECCCCEEEECCCCCCCCCCCH
HTIEHTIAVLLRERIPGYIDCSPFGCRTGFHLLTWGTHSTEDVAKALKESLEFIAYKATW
HHHHHHHHHHHHHHCCCEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHEEEECCC
DDVPATTEKSCGNYRDHSLFAAKEWAKQILEEGISSDPFERKVV
CCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA