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The map label for this gene is hexR [C]

Identifier: 213692847

GI number: 213692847

Start: 2167181

End: 2168050

Strand: Reverse

Name: hexR [C]

Synonym: Blon_1988

Alternate gene names: 213692847

Gene position: 2168050-2167181 (Counterclockwise)

Preceding gene: 213692850

Following gene: 213692845

Centisome position: 76.54

GC content: 60.8

Gene sequence:

>870_bases
GTGCAGTCCTCGGTGGGAATACGCGAGCGCATCGACCACGTGTATCCGTCGCTGCGTCCGGCGGAGCGCGCCGTGGCCCA
GTATATTCGGGATCATATCGAGGAGGCGGCCGACCTGACCGTCGGTCAGATGGCCGACATCGCCCACGTCAGCCAGCCGA
CGGTGATTCGGTTCGCCCGCAAGCTCGGCTTCGGCGGTTACCGTGAACTGCGGTACGTGTTGCGCCATCCGGCCGCCGAG
CACAAAGTGACCTTCAATCCGTTGGATGGATTCGATCTGAATCCGTGGGATGGCGAGGATGAGATTCCCAGCAAAGCGGC
CGATGGCGCGAAGGCGCTGATCGATGAGCTGCACAGTGCGTTGGACCCCAAGGCCTATCGCAAGGCGGTCGCCCTACTCG
CCGAATCGGAGTTCATCGACATTTTCGGCGTGGAGAACTCGTTGACACCGGCGATGGATCTGTTCACCAAGCTCGGCTAC
CTGGGACTGACGTGCCGTCTCAATACTGACGCTTACCTGCAGCAGATCGGTGCCGGGCACCTGACCCACGGCGCTGTGGC
CGTTGCCTTCTCTCATTCGGGCAGTTCGGCGGATACTGTCAAAGCGTTGCGATTGGCGAAATCGCATGGTGCGAAAACCA
TCGCCATTACCAATGCCATCGGCGCGCCGCTGGCCAGTTGGGCCGACGTGACGTTGCTGACGGGTCGTGACTCGCATACG
ATTTATGGCAATGCGATTTTTTCGTGCGTGGCCGATACCGCGCTCGTGGACATGCTGTACATGGGCGTGATTCTGTCCGA
CTACGGCCGGTTCTCCACCGCGCTCGACGAATCCGGTCGCATGATTCGCGATCGCGTATTCGAGAACTGA

Upstream 100 bases:

>100_bases
CACCGTTCATGTTGCGGTCAATCCAAGTCGATTGTTCGCCGGTATACAGCCGGTACCCTCGAAACGGGAATGGAAAATAC
GGGCGACTAGGAGCGTGGCT

Downstream 100 bases:

>100_bases
GCTGCTGCTTTATCGCGCCTTGGGCTGTATTGCTCTGGTCGTTGCTGCTTGGGTTGTTGACGATTTGGTCGTTGTCGCCC
TGGTCGCTACCGTCCTGAGG

Product: transcriptional regulator, RpiR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MQSSVGIRERIDHVYPSLRPAERAVAQYIRDHIEEAADLTVGQMADIAHVSQPTVIRFARKLGFGGYRELRYVLRHPAAE
HKVTFNPLDGFDLNPWDGEDEIPSKAADGAKALIDELHSALDPKAYRKAVALLAESEFIDIFGVENSLTPAMDLFTKLGY
LGLTCRLNTDAYLQQIGAGHLTHGAVAVAFSHSGSSADTVKALRLAKSHGAKTIAITNAIGAPLASWADVTLLTGRDSHT
IYGNAIFSCVADTALVDMLYMGVILSDYGRFSTALDESGRMIRDRVFEN

Sequences:

>Translated_289_residues
MQSSVGIRERIDHVYPSLRPAERAVAQYIRDHIEEAADLTVGQMADIAHVSQPTVIRFARKLGFGGYRELRYVLRHPAAE
HKVTFNPLDGFDLNPWDGEDEIPSKAADGAKALIDELHSALDPKAYRKAVALLAESEFIDIFGVENSLTPAMDLFTKLGY
LGLTCRLNTDAYLQQIGAGHLTHGAVAVAFSHSGSSADTVKALRLAKSHGAKTIAITNAIGAPLASWADVTLLTGRDSHT
IYGNAIFSCVADTALVDMLYMGVILSDYGRFSTALDESGRMIRDRVFEN
>Mature_289_residues
MQSSVGIRERIDHVYPSLRPAERAVAQYIRDHIEEAADLTVGQMADIAHVSQPTVIRFARKLGFGGYRELRYVLRHPAAE
HKVTFNPLDGFDLNPWDGEDEIPSKAADGAKALIDELHSALDPKAYRKAVALLAESEFIDIFGVENSLTPAMDLFTKLGY
LGLTCRLNTDAYLQQIGAGHLTHGAVAVAFSHSGSSADTVKALRLAKSHGAKTIAITNAIGAPLASWADVTLLTGRDSHT
IYGNAIFSCVADTALVDMLYMGVILSDYGRFSTALDESGRMIRDRVFEN

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=284, Percent_Identity=26.7605633802817, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788767, Length=258, Percent_Identity=25.968992248062, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI87082369, Length=265, Percent_Identity=23.3962264150943, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31446; Mature: 31446

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSSVGIRERIDHVYPSLRPAERAVAQYIRDHIEEAADLTVGQMADIAHVSQPTVIRFAR
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
KLGFGGYRELRYVLRHPAAEHKVTFNPLDGFDLNPWDGEDEIPSKAADGAKALIDELHSA
HHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHH
LDPKAYRKAVALLAESEFIDIFGVENSLTPAMDLFTKLGYLGLTCRLNTDAYLQQIGAGH
CCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEEECCHHHHHHHCCCC
LTHGAVAVAFSHSGSSADTVKALRLAKSHGAKTIAITNAIGAPLASWADVTLLTGRDSHT
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECHHCCCHHCCCCEEEEECCCCCE
IYGNAIFSCVADTALVDMLYMGVILSDYGRFSTALDESGRMIRDRVFEN
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MQSSVGIRERIDHVYPSLRPAERAVAQYIRDHIEEAADLTVGQMADIAHVSQPTVIRFAR
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
KLGFGGYRELRYVLRHPAAEHKVTFNPLDGFDLNPWDGEDEIPSKAADGAKALIDELHSA
HHCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHH
LDPKAYRKAVALLAESEFIDIFGVENSLTPAMDLFTKLGYLGLTCRLNTDAYLQQIGAGH
CCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHEEEEEECCHHHHHHHCCCC
LTHGAVAVAFSHSGSSADTVKALRLAKSHGAKTIAITNAIGAPLASWADVTLLTGRDSHT
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEECHHCCCHHCCCCEEEEECCCCCE
IYGNAIFSCVADTALVDMLYMGVILSDYGRFSTALDESGRMIRDRVFEN
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]