Click here to switch to the map view.

The map label for this gene is purE [H]

Identifier: 213692840

GI number: 213692840

Start: 2158096

End: 2158602

Strand: Reverse

Name: purE [H]

Synonym: Blon_1981

Alternate gene names: 213692840

Gene position: 2158602-2158096 (Counterclockwise)

Preceding gene: 213692841

Following gene: 213692839

Centisome position: 76.2

GC content: 64.1

Gene sequence:

>507_bases
ATGATAATGGCAAATGAATCCAAGCCCGAAGTCGCAGTGGTCATGGGATCGGCCAGCGACTGGGAGACCATGAAGCGCGC
CTGCGATATTCTCGACCAGTTCGGCGTCGCCTACCACAAGCAGGTCATCTCCGCGCACCGCACGCCCGAGCTCATGGCCG
AGTTCGCGCACAACGCCCGCGCCAATGGCCTGAAGGTCATTATCGCCGGTGCCGGCGGTGCCGCCCACCTGCCGGGCATG
ATCGCCGCGCAGACCACACTGCCCGTAATCGGCGTGCCCGTGCGCTCCCACGCCCTGTCCGGCTGGGATTCGCTGCTGTC
CATCGTGCAGATGCCCGGCGGCATTCCGGTGGCCACCACCGCCGTCGGCAACTCCGGTGCCACCAACGCCGGCCTGCTCG
CCGTGCAGATGCTCTCCGCCTTCGAGCCCGAACTGGCCGACAAGCTTGAGGATTACCGTAACGAACTGAAAGAAAAGGTG
GCTGAATCCAATGCCCAGCTTGTCTGA

Upstream 100 bases:

>100_bases
GGAGCGGGTCTGCGGGGCGGACCCGGGGAAAACCGCAAGGCGTTGCCGAAGTAAGCGCCCAAGCGTACAGTGGGCCTTAT
TCTCAATAACTAGGGAGTAA

Downstream 100 bases:

>100_bases
GGAAACAGGCGGTCGTGTTTCGATGCTGATGCCGGGATCGACCATCGGCATCATCGGCGGCGGCCAGCTCGGCCGCATGA
TGGCTTTGTCCGCCCGCTAC

Product: phosphoribosylaminoimidazole carboxylase, catalytic subunit

Products: NA

Alternate protein names: N5-CAIR mutase; 5-(carboxyamino)imidazole ribonucleotide mutase [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MIMANESKPEVAVVMGSASDWETMKRACDILDQFGVAYHKQVISAHRTPELMAEFAHNARANGLKVIIAGAGGAAHLPGM
IAAQTTLPVIGVPVRSHALSGWDSLLSIVQMPGGIPVATTAVGNSGATNAGLLAVQMLSAFEPELADKLEDYRNELKEKV
AESNAQLV

Sequences:

>Translated_168_residues
MIMANESKPEVAVVMGSASDWETMKRACDILDQFGVAYHKQVISAHRTPELMAEFAHNARANGLKVIIAGAGGAAHLPGM
IAAQTTLPVIGVPVRSHALSGWDSLLSIVQMPGGIPVATTAVGNSGATNAGLLAVQMLSAFEPELADKLEDYRNELKEKV
AESNAQLV
>Mature_168_residues
MIMANESKPEVAVVMGSASDWETMKRACDILDQFGVAYHKQVISAHRTPELMAEFAHNARANGLKVIIAGAGGAAHLPGM
IAAQTTLPVIGVPVRSHALSGWDSLLSIVQMPGGIPVATTAVGNSGATNAGLLAVQMLSAFEPELADKLEDYRNELKEKV
AESNAQLV

Specific function: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) [H]

COG id: COG0041

COG function: function code F; Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AIR carboxylase family [H]

Homologues:

Organism=Escherichia coli, GI1786734, Length=162, Percent_Identity=56.1728395061728, Blast_Score=151, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6324702, Length=153, Percent_Identity=54.2483660130719, Blast_Score=164, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000031 [H]

Pfam domain/function: PF00731 AIRC [H]

EC number: =5.4.99.18 [H]

Molecular weight: Translated: 17646; Mature: 17646

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMANESKPEVAVVMGSASDWETMKRACDILDQFGVAYHKQVISAHRTPELMAEFAHNAR
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
ANGLKVIIAGAGGAAHLPGMIAAQTTLPVIGVPVRSHALSGWDSLLSIVQMPGGIPVATT
CCCEEEEEECCCCCHHCCCHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEE
AVGNSGATNAGLLAVQMLSAFEPELADKLEDYRNELKEKVAESNAQLV
ECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIMANESKPEVAVVMGSASDWETMKRACDILDQFGVAYHKQVISAHRTPELMAEFAHNAR
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
ANGLKVIIAGAGGAAHLPGMIAAQTTLPVIGVPVRSHALSGWDSLLSIVQMPGGIPVATT
CCCEEEEEECCCCCHHCCCHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEE
AVGNSGATNAGLLAVQMLSAFEPELADKLEDYRNELKEKVAESNAQLV
ECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3036807; 9384377 [H]