Click here to switch to the map view.

The map label for this gene is glmU [H]

Identifier: 213692594

GI number: 213692594

Start: 1895056

End: 1896438

Strand: Direct

Name: glmU [H]

Synonym: Blon_1727

Alternate gene names: 213692594

Gene position: 1895056-1896438 (Clockwise)

Preceding gene: 213692593

Following gene: 213692595

Centisome position: 66.9

GC content: 66.81

Gene sequence:

>1383_bases
ATGGCATTATCCGCAGCCATCGTCCTCGCCGCCGGCGAGGGTACCCGCATGCGTTCCAACAAGCCGAAGGTGCTGCATAC
TTTTGCAGGCAAGACCTTCCTGAACAGGGTCATGGATTCGGTGGCCGCCCTGAATCCCGACACGCTGGCCGTGGTCGTGC
ACTTCCAGGCCGAGCGCGTCGCCGAAGCCGCCCGCTCCTATGACGAGCAGGTCACCATCGTGAACCAGGACGACATCCCC
GGCACCGGCCGCGCCGTCCAGTGCGCGATGGCCCAGCTCACCGAATCCGGCAAGATCGACGGCCCGGTGCTCATCGCCGC
CTCCGACATGCCGCTGCTCGACAGCGAGACGCTGCACCGCCTGGTCGAATTCCACACCGCCTCCGGCAATGGCGCCACCG
TGCTCACCACCATCCTCGACGACCCGACCGGTTATGGCCGCATCATCCGCGACCGCGAAGGCAACGTGCTGCGCATCGTC
GAGCAGAAGGACGCCAACCGCAGCGAACTCGCCGTGCAGGAGGTGAACACCTCGGTCTACGTGTTCGAGGCCTCCGTGCT
CGCCGAGGCGATCGCCGGACTGAAGTCGAACAACGCGCAGGGCGAGTTCTACCTGACCGACGCACTGGAAACCGCCAAGT
CGGCCGGCAAGGTCGGCGCGTTCGCCGCCCCGGACCCGCTCACCGTCGAGGGCGTGAACGACCGCGTGCAGCTGGCCGCC
CTGTCCAAGACCTACAACCGCCGCGTCTGCGAACGCTGGATGCGCAATGGCGTGACCATTCTCGATCCGGAGACCACCTG
GATCGAGGACGACGTGCGGATCGGCCGTGACGCCACCATCCTGCCCGGCTCCTTCCTGCAAGGCCATACGGTGATCGGCG
AGGACGCCGTCGTCGGCCCGTACACCACCCTTATCGACGCGACCGTGGACGAGGGTGCGGTGGTCGAACGTTCCCGTGTG
CAGGAATCGCATATCGGGGCGCGCACGAACATCGGACCGTGGACCTACCTGCGTGTGGGCAACGAGTTCGGCGAGGACGC
CAAGGCCGGCGCATTCGTCGAGATGAAGAAGACGCACATCGGCAACGGCACCAAAGTGCCGCACCTGAGCTATGTGGGCG
ACGCCCGGCTCGGCGACCACACCAACATCGGCGGCGGCACCATCACCGCCAACTACGATGGCGTGCACAAGAACCGCACC
GTGATCGGCGACGGCTGCCATGTGGGCGCCGGCAACCTGTTCGTGGCCCCGGTCGAGGTCGGCGACAACGTGACCACCGG
CGCCGGCTCCGTGGTGCGCCACGCCGTGCCGGACGACACGATGGTCTACTCCGAGAACACGCAGCACAACGTCGAGGGCT
GGAAGCCCGCCTGGGAGCGCTGA

Upstream 100 bases:

>100_bases
GGGGAACGGCTGACGGCCGCTCGACATCCGGGCGGCCGTCTATTGTTTTGAGGTGTTTCCGCCCTCAATAGACATTCCAA
TCGAAGGGAATACGTCAGTT

Downstream 100 bases:

>100_bases
ACCATGCCCGCACTTCAGGATTCCATCAACGCCGTCCGCGTGGCCGCCGAGGCCGCAGACCGTCTCAAGGCCACCGATAT
CGTGGCCTTCGACGTGGCCG

Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MALSAAIVLAAGEGTRMRSNKPKVLHTFAGKTFLNRVMDSVAALNPDTLAVVVHFQAERVAEAARSYDEQVTIVNQDDIP
GTGRAVQCAMAQLTESGKIDGPVLIAASDMPLLDSETLHRLVEFHTASGNGATVLTTILDDPTGYGRIIRDREGNVLRIV
EQKDANRSELAVQEVNTSVYVFEASVLAEAIAGLKSNNAQGEFYLTDALETAKSAGKVGAFAAPDPLTVEGVNDRVQLAA
LSKTYNRRVCERWMRNGVTILDPETTWIEDDVRIGRDATILPGSFLQGHTVIGEDAVVGPYTTLIDATVDEGAVVERSRV
QESHIGARTNIGPWTYLRVGNEFGEDAKAGAFVEMKKTHIGNGTKVPHLSYVGDARLGDHTNIGGGTITANYDGVHKNRT
VIGDGCHVGAGNLFVAPVEVGDNVTTGAGSVVRHAVPDDTMVYSENTQHNVEGWKPAWER

Sequences:

>Translated_460_residues
MALSAAIVLAAGEGTRMRSNKPKVLHTFAGKTFLNRVMDSVAALNPDTLAVVVHFQAERVAEAARSYDEQVTIVNQDDIP
GTGRAVQCAMAQLTESGKIDGPVLIAASDMPLLDSETLHRLVEFHTASGNGATVLTTILDDPTGYGRIIRDREGNVLRIV
EQKDANRSELAVQEVNTSVYVFEASVLAEAIAGLKSNNAQGEFYLTDALETAKSAGKVGAFAAPDPLTVEGVNDRVQLAA
LSKTYNRRVCERWMRNGVTILDPETTWIEDDVRIGRDATILPGSFLQGHTVIGEDAVVGPYTTLIDATVDEGAVVERSRV
QESHIGARTNIGPWTYLRVGNEFGEDAKAGAFVEMKKTHIGNGTKVPHLSYVGDARLGDHTNIGGGTITANYDGVHKNRT
VIGDGCHVGAGNLFVAPVEVGDNVTTGAGSVVRHAVPDDTMVYSENTQHNVEGWKPAWER
>Mature_459_residues
ALSAAIVLAAGEGTRMRSNKPKVLHTFAGKTFLNRVMDSVAALNPDTLAVVVHFQAERVAEAARSYDEQVTIVNQDDIPG
TGRAVQCAMAQLTESGKIDGPVLIAASDMPLLDSETLHRLVEFHTASGNGATVLTTILDDPTGYGRIIRDREGNVLRIVE
QKDANRSELAVQEVNTSVYVFEASVLAEAIAGLKSNNAQGEFYLTDALETAKSAGKVGAFAAPDPLTVEGVNDRVQLAAL
SKTYNRRVCERWMRNGVTILDPETTWIEDDVRIGRDATILPGSFLQGHTVIGEDAVVGPYTTLIDATVDEGAVVERSRVQ
ESHIGARTNIGPWTYLRVGNEFGEDAKAGAFVEMKKTHIGNGTKVPHLSYVGDARLGDHTNIGGGTITANYDGVHKNRTV
IGDGCHVGAGNLFVAPVEVGDNVTTGAGSVVRHAVPDDTMVYSENTQHNVEGWKPAWER

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=453, Percent_Identity=37.5275938189845, Blast_Score=285, Evalue=6e-78,
Organism=Caenorhabditis elegans, GI133931050, Length=377, Percent_Identity=24.4031830238727, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 49282; Mature: 49151

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSAAIVLAAGEGTRMRSNKPKVLHTFAGKTFLNRVMDSVAALNPDTLAVVVHFQAERV
CCCEEEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHH
AEAARSYDEQVTIVNQDDIPGTGRAVQCAMAQLTESGKIDGPVLIAASDMPLLDSETLHR
HHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHH
LVEFHTASGNGATVLTTILDDPTGYGRIIRDREGNVLRIVEQKDANRSELAVQEVNTSVY
HHHHCCCCCCCCEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCHHHEEHEECCCEEE
VFEASVLAEAIAGLKSNNAQGEFYLTDALETAKSAGKVGAFAAPDPLTVEGVNDRVQLAA
EEEHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEE
LSKTYNRRVCERWMRNGVTILDPETTWIEDDVRIGRDATILPGSFLQGHTVIGEDAVVGP
HHHHHHHHHHHHHHHCCCEEECCCCCEECCCHHCCCCCEECCCCCCCCCEEECCCCEECC
YTTLIDATVDEGAVVERSRVQESHIGARTNIGPWTYLRVGNEFGEDAKAGAFVEMKKTHI
HHHEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEHCC
GNGTKVPHLSYVGDARLGDHTNIGGGTITANYDGVHKNRTVIGDGCHVGAGNLFVAPVEV
CCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCEECCCCEEEEEEEC
GDNVTTGAGSVVRHAVPDDTMVYSENTQHNVEGWKPAWER
CCCEECCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALSAAIVLAAGEGTRMRSNKPKVLHTFAGKTFLNRVMDSVAALNPDTLAVVVHFQAERV
CCEEEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEECHHHH
AEAARSYDEQVTIVNQDDIPGTGRAVQCAMAQLTESGKIDGPVLIAASDMPLLDSETLHR
HHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHH
LVEFHTASGNGATVLTTILDDPTGYGRIIRDREGNVLRIVEQKDANRSELAVQEVNTSVY
HHHHCCCCCCCCEEEEEEECCCCCCCEEEEECCCCEEEEEECCCCCHHHEEHEECCCEEE
VFEASVLAEAIAGLKSNNAQGEFYLTDALETAKSAGKVGAFAAPDPLTVEGVNDRVQLAA
EEEHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEEEEE
LSKTYNRRVCERWMRNGVTILDPETTWIEDDVRIGRDATILPGSFLQGHTVIGEDAVVGP
HHHHHHHHHHHHHHHCCCEEECCCCCEECCCHHCCCCCEECCCCCCCCCEEECCCCEECC
YTTLIDATVDEGAVVERSRVQESHIGARTNIGPWTYLRVGNEFGEDAKAGAFVEMKKTHI
HHHEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEHCC
GNGTKVPHLSYVGDARLGDHTNIGGGTITANYDGVHKNRTVIGDGCHVGAGNLFVAPVEV
CCCCCCCEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCEECCCCEEEEEEEC
GDNVTTGAGSVVRHAVPDDTMVYSENTQHNVEGWKPAWER
CCCEECCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA