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The map label for this gene is era [H]

Identifier: 213692452

GI number: 213692452

Start: 1732817

End: 1733881

Strand: Reverse

Name: era [H]

Synonym: Blon_1581

Alternate gene names: 213692452

Gene position: 1733881-1732817 (Counterclockwise)

Preceding gene: 213692453

Following gene: 213692450

Centisome position: 61.21

GC content: 60.75

Gene sequence:

>1065_bases
ATGACCGACCAGAACAACAGCACGAACGACGTCGATGACATTGACGTCACCGATGCTTCCGATGTTGCCGGCGTTGCCGA
AGTCGACGCGACCGGTGAAACGGAGAATGTGACCAAGCAGGACGTGCCGTATCGCTCCGGATTCGTGGCCGTGGTGGGCC
GCCCGAACGTCGGCAAATCCACGTTGATCAACACGTTGATCGGCAAGCAGATCGCCATCGCATCCTCTCGCCCGGAAACC
ACCCGTAAGGCGATTCGCGGCATCCTGACCGCCGACCACGCGCAGCTCGTGCTCGTGGACACGCCCGGTATCCACCGCCC
GCGTACGTTGCTTGGCCAGCGTCTGAACGACGTGGTCGACGAATCCTTGGCCGATGTGGACGTGGTGGCCTTCCTGCTGC
CCGCCGACCAGGAAATCGGCCCCGGCGACAAGCGTATTCTTTCCCGACTGCGTACCGACTTCGCCACCAAGCGTGAGGAC
GGTACGTTCAAGTGGCGCATCCCGCTGATTGCCATCGTCACCAAGATCGACGAGCTTGGCCGTCAGCAACTCATCAACAA
GCTCATCGAAATCAACGATTTCGCCGATTTCTCGGACATCGTGCCGGTGAGCGCCCTGAAGCACGACAATCTGGCTGAAG
TGAAGAACGTGCTCATTGAGCACACGCCCGAGGGCCCGCAGATGTACCCGGACGATCAGATCAGCGAGGAGCGTCCGGAA
GACACCATCGCCGAACTCGTGCGCGGTGCGTTCCTTGAGACCCTGGACGACGAGCTGCCGCATTCGCTGGCCGTGGTGGT
CGATTCCATCGACTATCCGGAAGACAACGAGACCGGTCAGGGCTATGACGGCAAGGCGCAGGTCAACGTGTCCATTTACG
TGGAGCGTGACTCCCAGAAGCCGATCATCATCGGCAAGGGCGCCTCGAACCTCACCTACGTCAAGAAGAAGCTGCGCACC
CCGGTCAACCGCATTGTCGGCCAAAAAGCCAAGCTCGACCTCCACGTCAAGGTAGCCAAAGGCTGGCAGTCCGACCCCAA
GCAGCTGGAGCGCCTAGGCTTCTAG

Upstream 100 bases:

>100_bases
GAACCGGCGCACGTCGAGGGCGGCGAGGAAAATAGCAGGACCCATGAGGAAACTGACGGCGAGCCCGTCGAAGGCGATGA
TACCGCCAGCAAGGAGTGAT

Downstream 100 bases:

>100_bases
GGCGTATAGACGAAAAAGCTCCCTCGTCAGAGGGAGCTTTTGCTATACGGTTTACTTCCGCTTGGTGTACATCTGGGTGT
TGAGGAGGGTGGAGTAGCGC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MTDQNNSTNDVDDIDVTDASDVAGVAEVDATGETENVTKQDVPYRSGFVAVVGRPNVGKSTLINTLIGKQIAIASSRPET
TRKAIRGILTADHAQLVLVDTPGIHRPRTLLGQRLNDVVDESLADVDVVAFLLPADQEIGPGDKRILSRLRTDFATKRED
GTFKWRIPLIAIVTKIDELGRQQLINKLIEINDFADFSDIVPVSALKHDNLAEVKNVLIEHTPEGPQMYPDDQISEERPE
DTIAELVRGAFLETLDDELPHSLAVVVDSIDYPEDNETGQGYDGKAQVNVSIYVERDSQKPIIIGKGASNLTYVKKKLRT
PVNRIVGQKAKLDLHVKVAKGWQSDPKQLERLGF

Sequences:

>Translated_354_residues
MTDQNNSTNDVDDIDVTDASDVAGVAEVDATGETENVTKQDVPYRSGFVAVVGRPNVGKSTLINTLIGKQIAIASSRPET
TRKAIRGILTADHAQLVLVDTPGIHRPRTLLGQRLNDVVDESLADVDVVAFLLPADQEIGPGDKRILSRLRTDFATKRED
GTFKWRIPLIAIVTKIDELGRQQLINKLIEINDFADFSDIVPVSALKHDNLAEVKNVLIEHTPEGPQMYPDDQISEERPE
DTIAELVRGAFLETLDDELPHSLAVVVDSIDYPEDNETGQGYDGKAQVNVSIYVERDSQKPIIIGKGASNLTYVKKKLRT
PVNRIVGQKAKLDLHVKVAKGWQSDPKQLERLGF
>Mature_353_residues
TDQNNSTNDVDDIDVTDASDVAGVAEVDATGETENVTKQDVPYRSGFVAVVGRPNVGKSTLINTLIGKQIAIASSRPETT
RKAIRGILTADHAQLVLVDTPGIHRPRTLLGQRLNDVVDESLADVDVVAFLLPADQEIGPGDKRILSRLRTDFATKREDG
TFKWRIPLIAIVTKIDELGRQQLINKLIEINDFADFSDIVPVSALKHDNLAEVKNVLIEHTPEGPQMYPDDQISEERPED
TIAELVRGAFLETLDDELPHSLAVVVDSIDYPEDNETGQGYDGKAQVNVSIYVERDSQKPIIIGKGASNLTYVKKKLRTP
VNRIVGQKAKLDLHVKVAKGWQSDPKQLERLGF

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=311, Percent_Identity=33.1189710610932, Blast_Score=161, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24646434, Length=327, Percent_Identity=27.5229357798165, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 38997; Mature: 38866

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQNNSTNDVDDIDVTDASDVAGVAEVDATGETENVTKQDVPYRSGFVAVVGRPNVGKS
CCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHCCCCCCCEEEEEECCCCCHH
TLINTLIGKQIAIASSRPETTRKAIRGILTADHAQLVLVDTPGIHRPRTLLGQRLNDVVD
HHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
ESLADVDVVAFLLPADQEIGPGDKRILSRLRTDFATKREDGTFKWRIPLIAIVTKIDELG
HHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
RQQLINKLIEINDFADFSDIVPVSALKHDNLAEVKNVLIEHTPEGPQMYPDDQISEERPE
HHHHHHHHHHHCCCCCHHHCCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
DTIAELVRGAFLETLDDELPHSLAVVVDSIDYPEDNETGQGYDGKAQVNVSIYVERDSQK
HHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEECCCC
PIIIGKGASNLTYVKKKLRTPVNRIVGQKAKLDLHVKVAKGWQSDPKQLERLGF
CEEEECCCCHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHCCC
>Mature Secondary Structure 
TDQNNSTNDVDDIDVTDASDVAGVAEVDATGETENVTKQDVPYRSGFVAVVGRPNVGKS
CCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCHHCCCCCCCEEEEEECCCCCHH
TLINTLIGKQIAIASSRPETTRKAIRGILTADHAQLVLVDTPGIHRPRTLLGQRLNDVVD
HHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
ESLADVDVVAFLLPADQEIGPGDKRILSRLRTDFATKREDGTFKWRIPLIAIVTKIDELG
HHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHH
RQQLINKLIEINDFADFSDIVPVSALKHDNLAEVKNVLIEHTPEGPQMYPDDQISEERPE
HHHHHHHHHHHCCCCCHHHCCCHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCH
DTIAELVRGAFLETLDDELPHSLAVVVDSIDYPEDNETGQGYDGKAQVNVSIYVERDSQK
HHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCCCCEEEEEEEEEEEECCCC
PIIIGKGASNLTYVKKKLRTPVNRIVGQKAKLDLHVKVAKGWQSDPKQLERLGF
CEEEECCCCHHHHHHHHHHCHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA