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The map label for this gene is pntB [H]

Identifier: 213692448

GI number: 213692448

Start: 1727405

End: 1728829

Strand: Reverse

Name: pntB [H]

Synonym: Blon_1577

Alternate gene names: 213692448

Gene position: 1728829-1727405 (Counterclockwise)

Preceding gene: 213692449

Following gene: 213692446

Centisome position: 61.03

GC content: 62.32

Gene sequence:

>1425_bases
ATGACCTCCGCAACCGTTGGCGCCATCGACATCGTCGCTTGGTTCGCCTACCTGTTCTCTGCCGTCCTGTTTGTGGTCGG
TCTGCATTTCATGAATTCGCCGAAGACCGCCCGCAAAGGTAACCAGATCTCTGCGTTCGGCATGGTCGTGGCCGTGCTCA
TGGCGTTCATCGTGCTCTTCGCCAAGGGCTTCGTGAACATTGTCGCCGTGGTGGTGCTGGTCGTCGGCATCCTGATCGGT
GCCGTGGCCGGTGTCGTCTCCGCCAAGAAGGTGAAGATGACCGATATGCCGCAGCTGGTCTCCGTGTTCAATACCGTGGG
TGGTGGCGCCGCCGCACTCGTGGCCCTGAACGACATCCTGACCAAGGAAGGCACCCCGGACATCGTGGTGCTCATCACCG
CTGGTCTCGGTATTCTCATCGGTTCTGTGACCTTCACCGGCTCGCTCATCGCTGCCGGCAAGCTACAGGGCATCAAGTGG
GTCAAGAAGCTGAACCTGCCGGGCAAGGGCGTATGGAACATTCTGTTCGCCGTGCTGTCTGTCGCCTCGCTGGTCATGCT
GTGCGTCCAGCCCGAACAGCGTCTGCTGTGGTCGATTCTGACCACCGTGTTCGCCCTGTGCTACGGCTTGGTCTTCGTGA
TTCCAATCGGCGGCGCCGATATGCCCGTCGTCATCTCTGTGCTCAACGCCTGCACCGGTACGGCTGTGGCTATGTCCGGT
CTGGCGATTGACAACGTTGCCCTGATCGTGGCCGGCGCACTCGTCGGTTCCGCAGGTGTGACCCTGTCCATCCTCATGGC
TCAGGCCATGAACCGTCCGCTGCTCTCCGTCTTGGCCGGTGGCTTCGGCGGTGGTGCTGACGCCGCCGCTGCTGGCGACG
GTCTGGAAGGCACCATGAAGGAGACCACGCCGGACGATCTGGCCGTTCAGCTCGTCTACGCGCAGAAGGTCATCTTCGTG
CCCGGCTTCGGTCTGGCTCAGGCTCAGGCCCAGCGCGAGCTCGCTGACCTCGGCGAACTGCTCAAGGGCCACGGCGTGGA
AGTCTCCTACGCCATTCACCCGGTCGCAGGCCGTATGCCTGGTCACATGAACGTGCTGCTGGCCGAGGCCAACGTACCCT
ACGAGGAACTCGTGGATCTCGATGAGATCAACCCGCAGTTCCCACAGGCCAACGTGGCTCTGGTCGTCGGCGCCAACGAC
GTGACCAACCCGGCCGCTCGTCGCCCCGGCACCCCGGTCTCCGGCATGCCGATTCTCGACGTCGACAAGTCCCAGAACGT
CGTGGTCATGAAGCGTGGCCGTGGTATGGGCTATGCCGGCATCCAGAACGAGCTCTACTTCGAGAACAACACCCAGATGC
TGTTCGGCGATGCAAAGAAGAGCCTGCAGGCCGTCATCGCCGCCGTCAAGGAACTGCTCGCGTAA

Upstream 100 bases:

>100_bases
TGCTGGGCACCATGAACGTCGTTGGTGGCTACGTGGTCACCGACCGCATGCTTGAGATGTTCAAGTCCAGCAAGAACGAG
AAGAAGGGGGAGTCGAAGTA

Downstream 100 bases:

>100_bases
CCATTCTTGGCTCCCCTCTGTGAGGGGAGCCAAGCTCTATATCTACTACAGTCCAAACACCCGCTTAACAAAGCTGTTAA
CGCGACGCCAATAGCGGTCC

Product: NAD(P) transhydrogenase, beta subunit

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MTSATVGAIDIVAWFAYLFSAVLFVVGLHFMNSPKTARKGNQISAFGMVVAVLMAFIVLFAKGFVNIVAVVVLVVGILIG
AVAGVVSAKKVKMTDMPQLVSVFNTVGGGAAALVALNDILTKEGTPDIVVLITAGLGILIGSVTFTGSLIAAGKLQGIKW
VKKLNLPGKGVWNILFAVLSVASLVMLCVQPEQRLLWSILTTVFALCYGLVFVIPIGGADMPVVISVLNACTGTAVAMSG
LAIDNVALIVAGALVGSAGVTLSILMAQAMNRPLLSVLAGGFGGGADAAAAGDGLEGTMKETTPDDLAVQLVYAQKVIFV
PGFGLAQAQAQRELADLGELLKGHGVEVSYAIHPVAGRMPGHMNVLLAEANVPYEELVDLDEINPQFPQANVALVVGAND
VTNPAARRPGTPVSGMPILDVDKSQNVVVMKRGRGMGYAGIQNELYFENNTQMLFGDAKKSLQAVIAAVKELLA

Sequences:

>Translated_474_residues
MTSATVGAIDIVAWFAYLFSAVLFVVGLHFMNSPKTARKGNQISAFGMVVAVLMAFIVLFAKGFVNIVAVVVLVVGILIG
AVAGVVSAKKVKMTDMPQLVSVFNTVGGGAAALVALNDILTKEGTPDIVVLITAGLGILIGSVTFTGSLIAAGKLQGIKW
VKKLNLPGKGVWNILFAVLSVASLVMLCVQPEQRLLWSILTTVFALCYGLVFVIPIGGADMPVVISVLNACTGTAVAMSG
LAIDNVALIVAGALVGSAGVTLSILMAQAMNRPLLSVLAGGFGGGADAAAAGDGLEGTMKETTPDDLAVQLVYAQKVIFV
PGFGLAQAQAQRELADLGELLKGHGVEVSYAIHPVAGRMPGHMNVLLAEANVPYEELVDLDEINPQFPQANVALVVGAND
VTNPAARRPGTPVSGMPILDVDKSQNVVVMKRGRGMGYAGIQNELYFENNTQMLFGDAKKSLQAVIAAVKELLA
>Mature_473_residues
TSATVGAIDIVAWFAYLFSAVLFVVGLHFMNSPKTARKGNQISAFGMVVAVLMAFIVLFAKGFVNIVAVVVLVVGILIGA
VAGVVSAKKVKMTDMPQLVSVFNTVGGGAAALVALNDILTKEGTPDIVVLITAGLGILIGSVTFTGSLIAAGKLQGIKWV
KKLNLPGKGVWNILFAVLSVASLVMLCVQPEQRLLWSILTTVFALCYGLVFVIPIGGADMPVVISVLNACTGTAVAMSGL
AIDNVALIVAGALVGSAGVTLSILMAQAMNRPLLSVLAGGFGGGADAAAAGDGLEGTMKETTPDDLAVQLVYAQKVIFVP
GFGLAQAQAQRELADLGELLKGHGVEVSYAIHPVAGRMPGHMNVLLAEANVPYEELVDLDEINPQFPQANVALVVGANDV
TNPAARRPGTPVSGMPILDVDKSQNVVVMKRGRGMGYAGIQNELYFENNTQMLFGDAKKSLQAVIAAVKELLA

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=466, Percent_Identity=39.9141630901288, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI122939153, Length=466, Percent_Identity=39.9141630901288, Blast_Score=297, Evalue=1e-80,
Organism=Escherichia coli, GI1787886, Length=463, Percent_Identity=44.4924406047516, Blast_Score=354, Evalue=8e-99,
Organism=Caenorhabditis elegans, GI17550456, Length=472, Percent_Identity=39.6186440677966, Blast_Score=297, Evalue=7e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49077; Mature: 48946

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSATVGAIDIVAWFAYLFSAVLFVVGLHFMNSPKTARKGNQISAFGMVVAVLMAFIVLF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
AKGFVNIVAVVVLVVGILIGAVAGVVSAKKVKMTDMPQLVSVFNTVGGGAAALVALNDIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHCCCCHHHHHHHHHHH
TKEGTPDIVVLITAGLGILIGSVTFTGSLIAAGKLQGIKWVKKLNLPGKGVWNILFAVLS
HCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VASLVMLCVQPEQRLLWSILTTVFALCYGLVFVIPIGGADMPVVISVLNACTGTAVAMSG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCHHHHHCC
LAIDNVALIVAGALVGSAGVTLSILMAQAMNRPLLSVLAGGFGGGADAAAAGDGLEGTMK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ETTPDDLAVQLVYAQKVIFVPGFGLAQAQAQRELADLGELLKGHGVEVSYAIHPVAGRMP
CCCCHHHHEEHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
GHMNVLLAEANVPYEELVDLDEINPQFPQANVALVVGANDVTNPAARRPGTPVSGMPILD
CCCEEEEEECCCCHHHHCCHHHCCCCCCCCCEEEEECCCCCCCCHHCCCCCCCCCCEEEE
VDKSQNVVVMKRGRGMGYAGIQNELYFENNTQMLFGDAKKSLQAVIAAVKELLA
CCCCCCEEEEECCCCCCCCCCCCCEEEECCCEEEECHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TSATVGAIDIVAWFAYLFSAVLFVVGLHFMNSPKTARKGNQISAFGMVVAVLMAFIVLF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
AKGFVNIVAVVVLVVGILIGAVAGVVSAKKVKMTDMPQLVSVFNTVGGGAAALVALNDIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHCCCCHHHHHHHHHHH
TKEGTPDIVVLITAGLGILIGSVTFTGSLIAAGKLQGIKWVKKLNLPGKGVWNILFAVLS
HCCCCCCEEEEEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VASLVMLCVQPEQRLLWSILTTVFALCYGLVFVIPIGGADMPVVISVLNACTGTAVAMSG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCHHHHHCC
LAIDNVALIVAGALVGSAGVTLSILMAQAMNRPLLSVLAGGFGGGADAAAAGDGLEGTMK
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCC
ETTPDDLAVQLVYAQKVIFVPGFGLAQAQAQRELADLGELLKGHGVEVSYAIHPVAGRMP
CCCCHHHHEEHHHHCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCC
GHMNVLLAEANVPYEELVDLDEINPQFPQANVALVVGANDVTNPAARRPGTPVSGMPILD
CCCEEEEEECCCCHHHHCCHHHCCCCCCCCCEEEEECCCCCCCCHHCCCCCCCCCCEEEE
VDKSQNVVVMKRGRGMGYAGIQNELYFENNTQMLFGDAKKSLQAVIAAVKELLA
CCCCCCEEEEECCCCCCCCCCCCCEEEECCCEEEECHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]