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The map label for this gene is trmI [H]

Identifier: 213692332

GI number: 213692332

Start: 1619144

End: 1620214

Strand: Reverse

Name: trmI [H]

Synonym: Blon_1457

Alternate gene names: 213692332

Gene position: 1620214-1619144 (Counterclockwise)

Preceding gene: 213692334

Following gene: 213692331

Centisome position: 57.2

GC content: 62.93

Gene sequence:

>1071_bases
ATGGAGCCGAGGCGCGGGCCTCTCACCGCAGGTGAGAAGGTGCAGTTCACCGACCGCAAGGGCAAGAAGATCACCGATCA
GCTTGTGGCTGGCGGCTCCACGCAGACCGAGCATGGCCTGATTCTGCATGACGATGTGATCGGCAAGACCGAAGGCACCG
TCATCCTCACCGTGCACGCCAAGCGTGAGGCGCAGGTCAACCAGGTTTATCCAGAGAAAGACAAGAACAAGCCGTGGAAG
TCGTCGCGCGCCATCGGCGGCTGGGAATATGCGGTGATGCGCCCGCGACTGGCCGATTACGTGCTGTCGATGCCGCGCGG
CGCGCAGATCATGTATCCGAAGGACATCGCCCAGGTTGTCCAGCTCGGCGACATCCGTTCCGGCATGCGCGTGCTTGAGT
CCGGTGCCGGCTCGGGCGCGATGAGCGTGAACCTGCTGGACGCCGTGGGCGATCGTGGCCATCTGACCACGATCGAGCTG
CGCCCCGAATTCGCCAAAGTGGCTCAGGCCAACGCCACGCTGTATTACGGCGAGGCCCCCAGCTGGTGGGATCTCAAAAC
CGGCGACTTCGACTCCGTGGCCGCCGAACTGCCCGAACACTGGTTCGACCGCATCATGCTCGACATGCTCGACCCGTGGA
ACAGGCTCGACCAGGCATACCGCGTGATTGCCCCCGGCGGCGTGTTGGTCAGTTACGTAACTACCACCACGCAGATGAGC
CGACTGGCCGAAGCCCTGCGCGCGGCCGGCTGCTGGACCGAGCCGCAGATCCAGGAATCGTTCGAACGCACATGGAAGGC
CCAAGGCCTCGCCGTACGCCCCGACCACCAGATGATCGGCCATACCGGTTTCCTTGTTATCTCGCGCGCCATGGCCTCCG
GGTTCGAGGCGCTCAGAAAGCGCGATCGCGTGACCAAGGACACACAGACCGACATCGACTCGCTCACCGACGAACAGCGT
GAGGCGCAGATCGAGGAACTGGAACTGCGCGACATCTCCGACCACAAACTACGTAAGGTGTTGCGTGACCTCGACCGTCA
GGTGGGAGAACTTGGCAACACGCACGAATAA

Upstream 100 bases:

>100_bases
CTGGCTTGTCATCTGCATTCGCATCGTCATCACCTCACCAACGAGCTTACATGCATTAGACTTGTAGCGATTGACCCACC
GAGCACGCAAGGAGCAAGTT

Downstream 100 bases:

>100_bases
CCGCCAAACGATGAGTTTGTGAGCGCTCACACACCTCTATACTGGAAGCAACGCCACACCGCCACACCGGGCAGGCGGTT
CGTGAAGGGAGCCACGGATG

Product: protein-L-isoaspartate methyltransferase

Products: NA

Alternate protein names: tRNA(m1A58)-methyltransferase; tRNA(m1A58)MTase [H]

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MEPRRGPLTAGEKVQFTDRKGKKITDQLVAGGSTQTEHGLILHDDVIGKTEGTVILTVHAKREAQVNQVYPEKDKNKPWK
SSRAIGGWEYAVMRPRLADYVLSMPRGAQIMYPKDIAQVVQLGDIRSGMRVLESGAGSGAMSVNLLDAVGDRGHLTTIEL
RPEFAKVAQANATLYYGEAPSWWDLKTGDFDSVAAELPEHWFDRIMLDMLDPWNRLDQAYRVIAPGGVLVSYVTTTTQMS
RLAEALRAAGCWTEPQIQESFERTWKAQGLAVRPDHQMIGHTGFLVISRAMASGFEALRKRDRVTKDTQTDIDSLTDEQR
EAQIEELELRDISDHKLRKVLRDLDRQVGELGNTHE

Sequences:

>Translated_356_residues
MEPRRGPLTAGEKVQFTDRKGKKITDQLVAGGSTQTEHGLILHDDVIGKTEGTVILTVHAKREAQVNQVYPEKDKNKPWK
SSRAIGGWEYAVMRPRLADYVLSMPRGAQIMYPKDIAQVVQLGDIRSGMRVLESGAGSGAMSVNLLDAVGDRGHLTTIEL
RPEFAKVAQANATLYYGEAPSWWDLKTGDFDSVAAELPEHWFDRIMLDMLDPWNRLDQAYRVIAPGGVLVSYVTTTTQMS
RLAEALRAAGCWTEPQIQESFERTWKAQGLAVRPDHQMIGHTGFLVISRAMASGFEALRKRDRVTKDTQTDIDSLTDEQR
EAQIEELELRDISDHKLRKVLRDLDRQVGELGNTHE
>Mature_356_residues
MEPRRGPLTAGEKVQFTDRKGKKITDQLVAGGSTQTEHGLILHDDVIGKTEGTVILTVHAKREAQVNQVYPEKDKNKPWK
SSRAIGGWEYAVMRPRLADYVLSMPRGAQIMYPKDIAQVVQLGDIRSGMRVLESGAGSGAMSVNLLDAVGDRGHLTTIEL
RPEFAKVAQANATLYYGEAPSWWDLKTGDFDSVAAELPEHWFDRIMLDMLDPWNRLDQAYRVIAPGGVLVSYVTTTTQMS
RLAEALRAAGCWTEPQIQESFERTWKAQGLAVRPDHQMIGHTGFLVISRAMASGFEALRKRDRVTKDTQTDIDSLTDEQR
EAQIEELELRDISDHKLRKVLRDLDRQVGELGNTHE

Specific function: Catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. Is required for cell growth at extreme temperatures [H]

COG id: COG2519

COG function: function code J; tRNA(1-methyladenosine) methyltransferase and related methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. TrmI family [H]

Homologues:

Organism=Homo sapiens, GI222831587, Length=200, Percent_Identity=33.5, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI123173772, Length=293, Percent_Identity=24.2320819112628, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014816 [H]

Pfam domain/function: PF08704 GCD14 [H]

EC number: =2.1.1.36 [H]

Molecular weight: Translated: 39907; Mature: 39907

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPRRGPLTAGEKVQFTDRKGKKITDQLVAGGSTQTEHGLILHDDVIGKTEGTVILTVHA
CCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEEEEC
KREAQVNQVYPEKDKNKPWKSSRAIGGWEYAVMRPRLADYVLSMPRGAQIMYPKDIAQVV
CCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCHHHHHHHHCCCCCCEEECHHHHHHHH
QLGDIRSGMRVLESGAGSGAMSVNLLDAVGDRGHLTTIELRPEFAKVAQANATLYYGEAP
HHHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCEEEEEECHHHHHHHHCCCEEEECCCC
SWWDLKTGDFDSVAAELPEHWFDRIMLDMLDPWNRLDQAYRVIAPGGVLVSYVTTTTQMS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCEEEHHHHHHHHHH
RLAEALRAAGCWTEPQIQESFERTWKAQGLAVRPDHQMIGHTGFLVISRAMASGFEALRK
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCHHHHCCHHHHHHHHHHHHHHHHHHH
RDRVTKDTQTDIDSLTDEQREAQIEELELRDISDHKLRKVLRDLDRQVGELGNTHE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEPRRGPLTAGEKVQFTDRKGKKITDQLVAGGSTQTEHGLILHDDVIGKTEGTVILTVHA
CCCCCCCCCCCCEEEECCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEEEEC
KREAQVNQVYPEKDKNKPWKSSRAIGGWEYAVMRPRLADYVLSMPRGAQIMYPKDIAQVV
CCCCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHCHHHHHHHHCCCCCCEEECHHHHHHHH
QLGDIRSGMRVLESGAGSGAMSVNLLDAVGDRGHLTTIELRPEFAKVAQANATLYYGEAP
HHHHHHHHHHHHHCCCCCCCEEEEHHHHCCCCCCEEEEEECHHHHHHHHCCCEEEECCCC
SWWDLKTGDFDSVAAELPEHWFDRIMLDMLDPWNRLDQAYRVIAPGGVLVSYVTTTTQMS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCCCEEEHHHHHHHHHH
RLAEALRAAGCWTEPQIQESFERTWKAQGLAVRPDHQMIGHTGFLVISRAMASGFEALRK
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCHHHHCCHHHHHHHHHHHHHHHHHHH
RDRVTKDTQTDIDSLTDEQREAQIEELELRDISDHKLRKVLRDLDRQVGELGNTHE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA