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The map label for this gene is sucD [H]

Identifier: 213692044

GI number: 213692044

Start: 1343141

End: 1344052

Strand: Direct

Name: sucD [H]

Synonym: Blon_1162

Alternate gene names: 213692044

Gene position: 1343141-1344052 (Clockwise)

Preceding gene: 213692043

Following gene: 213692045

Centisome position: 47.41

GC content: 65.46

Gene sequence:

>912_bases
ATGCTGTTCATCGAAGACGGCGCTCCGGTCATCGTCCAGGGCATGACCGGCCATCAGGGCATGACCCATACGGCGCGCAT
GCTCAATGCCGGCACCAATATCGTCGGCGGCGTGAATCCGCGCAAGGCCGGGATGCACGTCACCTTCCCCGGTGCCCAAG
GTGGCGCCGACGCCGATATCCCCGTGTTCGCCACCTGCGCCGACGCCCGTGAAGCCACCGGCGCCAAGGCCAGCGTGGTG
TTCGTGCCGCCGAAGTTCGCCAAGTCCGCCGTGGTCGAAGCAGTCGAAGCCGGCATCGAACTCATCGTGGTTATCACCGA
AGGCATTCCAGTAGCCGATTCCTCGTATTTCGTCGAACTCGCGCTCACCAGGGGCGTGCGCATCATCGGACCGAATTGCC
CCGGCCTCATCACCCTCGGTAACCCAGGCGTCAACCTGGGCATCATCCCCGACGGCATCGTCGGCCGCGGCCCGCTCGGA
CTGGTCTCCAAATCCGGCACCCTCACCTACCAGCTCATGGGCGAATTGTCCGATATCGGCTTCACCGGATGTCTCGGCGC
CGGCGGCGATCCGATCGTCGGCACGACGCTGCTGGAAGCCCTGCAGGCATTCGAAGCCGACCCCGACACCAAGGCTGTCA
TGATGATCGGCGAAATCGGCGGCTTCGCCGAACAGGACGCCGCCGCATGGGCCAAGGAGCACATGACCAAGCCGGTCGTC
GCCTACATCGCCGGTTTCACCGCCCCCGAAGGCAAGCAGATGGGCCACGCCGGCGCCATCGTCTCCGGTGGCAAGGGCAC
CGCCCAGGACAAGAAGAACGCACTCGAAGCGGCGGGTATCCCCGTGGGCAAGACCCCGGGCCAGGCCGCCGAAATCATGC
GCGACATACTCGCCAAGGCCGACATCGACTGA

Upstream 100 bases:

>100_bases
CGAACAAACCGAATATCCATGTGTCCGAAACCATGGAAGACGCGGCGGCCAAGGCCGCGCAGCTCGCCGGTGAGGCGATT
CAGTCCAAGGAGGTTCTCTG

Downstream 100 bases:

>100_bases
TCGGTTCCGACCAATCGTGATGAAAGCCGTGATTCGCCAATGGGTGCGGGGAGCCATAGTCGCTCTCGCATCCATGGCCA
TCTATGCCATTGCATTAGGC

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MLFIEDGAPVIVQGMTGHQGMTHTARMLNAGTNIVGGVNPRKAGMHVTFPGAQGGADADIPVFATCADAREATGAKASVV
FVPPKFAKSAVVEAVEAGIELIVVITEGIPVADSSYFVELALTRGVRIIGPNCPGLITLGNPGVNLGIIPDGIVGRGPLG
LVSKSGTLTYQLMGELSDIGFTGCLGAGGDPIVGTTLLEALQAFEADPDTKAVMMIGEIGGFAEQDAAAWAKEHMTKPVV
AYIAGFTAPEGKQMGHAGAIVSGGKGTAQDKKNALEAAGIPVGKTPGQAAEIMRDILAKADID

Sequences:

>Translated_303_residues
MLFIEDGAPVIVQGMTGHQGMTHTARMLNAGTNIVGGVNPRKAGMHVTFPGAQGGADADIPVFATCADAREATGAKASVV
FVPPKFAKSAVVEAVEAGIELIVVITEGIPVADSSYFVELALTRGVRIIGPNCPGLITLGNPGVNLGIIPDGIVGRGPLG
LVSKSGTLTYQLMGELSDIGFTGCLGAGGDPIVGTTLLEALQAFEADPDTKAVMMIGEIGGFAEQDAAAWAKEHMTKPVV
AYIAGFTAPEGKQMGHAGAIVSGGKGTAQDKKNALEAAGIPVGKTPGQAAEIMRDILAKADID
>Mature_303_residues
MLFIEDGAPVIVQGMTGHQGMTHTARMLNAGTNIVGGVNPRKAGMHVTFPGAQGGADADIPVFATCADAREATGAKASVV
FVPPKFAKSAVVEAVEAGIELIVVITEGIPVADSSYFVELALTRGVRIIGPNCPGLITLGNPGVNLGIIPDGIVGRGPLG
LVSKSGTLTYQLMGELSDIGFTGCLGAGGDPIVGTTLLEALQAFEADPDTKAVMMIGEIGGFAEQDAAAWAKEHMTKPVV
AYIAGFTAPEGKQMGHAGAIVSGGKGTAQDKKNALEAAGIPVGKTPGQAAEIMRDILAKADID

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=296, Percent_Identity=45.945945945946, Blast_Score=188, Evalue=5e-48,
Organism=Homo sapiens, GI38569421, Length=257, Percent_Identity=31.1284046692607, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI38569423, Length=257, Percent_Identity=31.1284046692607, Blast_Score=95, Evalue=7e-20,
Organism=Escherichia coli, GI1786949, Length=299, Percent_Identity=49.1638795986622, Blast_Score=265, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17550194, Length=294, Percent_Identity=47.9591836734694, Blast_Score=234, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17553126, Length=303, Percent_Identity=45.2145214521452, Blast_Score=218, Evalue=4e-57,
Organism=Caenorhabditis elegans, GI17557344, Length=234, Percent_Identity=29.9145299145299, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551266, Length=235, Percent_Identity=31.063829787234, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6324716, Length=310, Percent_Identity=42.5806451612903, Blast_Score=207, Evalue=1e-54,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=45.2054794520548, Blast_Score=228, Evalue=3e-60,
Organism=Drosophila melanogaster, GI28574296, Length=303, Percent_Identity=43.2343234323432, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI281363477, Length=251, Percent_Identity=30.2788844621514, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281363475, Length=251, Percent_Identity=30.2788844621514, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281363473, Length=251, Percent_Identity=30.2788844621514, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30699; Mature: 30699

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFIEDGAPVIVQGMTGHQGMTHTARMLNAGTNIVGGVNPRKAGMHVTFPGAQGGADADI
CEEECCCCCEEEECCCCCCCCHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCCCCCCCC
PVFATCADAREATGAKASVVFVPPKFAKSAVVEAVEAGIELIVVITEGIPVADSSYFVEL
CEEEEECCHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEE
ALTRGVRIIGPNCPGLITLGNPGVNLGIIPDGIVGRGPLGLVSKSGTLTYQLMGELSDIG
EECCCEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCCCEEECCCCEEEEEEHHHHHCC
FTGCLGAGGDPIVGTTLLEALQAFEADPDTKAVMMIGEIGGFAEQDAAAWAKEHMTKPVV
CEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHH
AYIAGFTAPEGKQMGHAGAIVSGGKGTAQDKKNALEAAGIPVGKTPGQAAEIMRDILAKA
HHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
DID
CCC
>Mature Secondary Structure
MLFIEDGAPVIVQGMTGHQGMTHTARMLNAGTNIVGGVNPRKAGMHVTFPGAQGGADADI
CEEECCCCCEEEECCCCCCCCHHHHHHHHCCCCEECCCCCCCCCEEEECCCCCCCCCCCC
PVFATCADAREATGAKASVVFVPPKFAKSAVVEAVEAGIELIVVITEGIPVADSSYFVEL
CEEEEECCHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEE
ALTRGVRIIGPNCPGLITLGNPGVNLGIIPDGIVGRGPLGLVSKSGTLTYQLMGELSDIG
EECCCEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCCCEEECCCCEEEEEEHHHHHCC
FTGCLGAGGDPIVGTTLLEALQAFEADPDTKAVMMIGEIGGFAEQDAAAWAKEHMTKPVV
CEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHH
AYIAGFTAPEGKQMGHAGAIVSGGKGTAQDKKNALEAAGIPVGKTPGQAAEIMRDILAKA
HHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
DID
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]