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The map label for this gene is tkt [H]

Identifier: 213691978

GI number: 213691978

Start: 1283617

End: 1285725

Strand: Reverse

Name: tkt [H]

Synonym: Blon_1096

Alternate gene names: 213691978

Gene position: 1285725-1283617 (Counterclockwise)

Preceding gene: 213691981

Following gene: 213691977

Centisome position: 45.39

GC content: 66.95

Gene sequence:

>2109_bases
ATGACCGAATTCAAGGAGACCGAGCTCGACGAGCGCGCCATCAAGATGGCGAAGGTCCTTTCGGCTGACGCGGTTGAGAA
GGCGGGCTCCGGCCACCCCGGCTCCCCCGTCTCCCTGGCGCCCGTCGCCTACACGCTGTACCAGCACTTCATCAAGCACG
ATCCGAATGATCCCAACTGGGAAGGCCGCGATCGCTTCATCCTTTCCGGTGGCCACGCCTCCCTCACCCAGTACGTCCAG
CTGTACTTCTCCGGTTACGGCGTGACCCTGGACGACCTCAAGAGCTTCCGTGGCAGCGCGGCCACCCGCACCCCGGGCCA
CCCGGAGTACGGCCTGACCCCGGGCATCGAAATGACCACCGGTCCTCTGGGTCAGGGTCTCGCCTCCGCCATCGGCTTCG
CCTACGGCGAGCGTTTCCAGCGCGGTCTGCTTGACCCGGAGACCCCGAAGGAAGATTCCCCGTTCTACCACAAGATCTGG
GCCATCTGCGGCGAAGGCGACATCGAGGAGGGCATCTCCGGCGAGGCCGCTTCCCTGGCCGCCAACCAGAAGCTCGGCAA
CCTGACCGTGATCTTCGACGCCAACCGCATCCAAATCGAAGGCGACACCAACCTGGTGCTGGCCGAGGACGTGCTCAAGC
GCTTCCAGGCATACGGCTGGTACACCGACGAGTTCAGCTTCATCCAGCCCGACGGCTCCTACAAGGAGGACATCGAAGGC
CTGGCCGACGTCATCGCCAAGGCCGAGAAGGCCGCTCCGGACCAGCCGAAGCTCATCAAGGTCCACTCCCTGATCGCCTG
GCCGACCCCGGGCAAGACCAACGACCCGTCCTCCCACGGCTCCAAGCTGGGCGCCGAGGCCGTCGCCGGCCTCAAGAAGC
TCCTCGGCTACGATCCGGAGGAGTCCTTCCACGTCGACGAAGAAGCCCTGGCCCACGCCCGCAAGGTCGCCGATCGCGGC
CTGGAAGCCCACAAGGCCTGGGACGAGAAGTTCGACGCCTGGCGCAAGGCCAACCCGGACAAGGCCGCCCTGTACGACCG
CCTGAAGGCCGGCGAGCTGCCGGAAGGCTTCGATAAGGCCCTGGACGACCTTGAGGCCACCTTCGAAGTCGGCAAGAACG
TCGCCACCCGCGGCGCCTCCGGCTCCGTGCTCAACGCCATCGCCGCCGTCATGCCGGAACTCTGGGGCGGCTCCGCCGAC
CTCGGCGGCTCCAACAAGACCGACCTCAAGGGCGCCGCCACCTTCGCCCCGGCCGAGTGCGCCACCGTTCAGTGGCCGAA
TTGCAACGAGTTCGGCCGCCAGCTTCACTTCGGCGTGCGTGAGTTCGCCATGGGCTGCATCACCAACGGCATCCTGCTCG
GTTCGCACACCCGTCCGTTCGGCGGTACCTTCTTCATGTTCTCCGACTACGAGCGTTCCGCCGTCCGTCTGGCCGCCCTC
ATGCAGATCCCGAACCTGTACATCTGGTCCCACGACTCCGTCGCCGTCGGCGAGGACGGCCCGACCCATCAGCCGGTCGA
GCACCTGGCCTCCTTCCGCGCGATTCCTCAGCTTGAGGTCATCCGCCCGGCCGACGCCTTCGAGACCGCCGAGGCCTACC
GCTACTTCTTCGAGAAGAAGAACACGCTGCCCGGCGCCATGATCCTGACCCGTCAGGGCGTCCCGGTGCTCGCCGAGACC
GCCGCCAAGGCCAAGGAAGGCGTTCGCAAGGGCGCCTACGTGCTCGTGGACACCGAGGGCACCCCGGACGTCATCCTCAT
GGCTTCCGGCTCCGAGGTCCAGTGGGCCGTGGCCGCCGCCAAGACCCTGGCCGGCGAGGGCGTCAAGGCTCGCGTCGTGT
CCGTGCCGTCCCTCGAATGGTTCGAGGAGCAGGACGCCGAGTACAAGGAGGCCGTGCTGCCGGCCGCCGTCAAGGCCCGC
GTCTCCGTCGAGGCCGGCGTCGCCATGCCGTGGTACAAGTACCTCGGCTCCTACGGCAAGCCCGTCTCCATCGAGCAGTT
CGGCCTGCAGGGCGATGGCGCTCAGAACATGATCGACCTTGGCATCACCGCCGAGCACGTCGTGGAAGCCGCCAAGGCCT
CCATCGCCGAAGCCGAAGCCGCCAAGTGA

Upstream 100 bases:

>100_bases
CGTCGCAAACCGACGGTAGCATGGTAATCGCAATGTGAGGGCGTCAAGCGCCCGGCACAAGCCGGATACGCGGCCCGACC
AATTGGAAGGAAAGTAATCC

Downstream 100 bases:

>100_bases
TCATGCGTCTCCCGCTGGCGAGTTGAGTCGTCAGTCTCCACAGCGGGAGACGATCGTATGACGGATGGGCCAAGACCGCC
GGCGTGGCCGGTCATCGAAG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MTEFKETELDERAIKMAKVLSADAVEKAGSGHPGSPVSLAPVAYTLYQHFIKHDPNDPNWEGRDRFILSGGHASLTQYVQ
LYFSGYGVTLDDLKSFRGSAATRTPGHPEYGLTPGIEMTTGPLGQGLASAIGFAYGERFQRGLLDPETPKEDSPFYHKIW
AICGEGDIEEGISGEAASLAANQKLGNLTVIFDANRIQIEGDTNLVLAEDVLKRFQAYGWYTDEFSFIQPDGSYKEDIEG
LADVIAKAEKAAPDQPKLIKVHSLIAWPTPGKTNDPSSHGSKLGAEAVAGLKKLLGYDPEESFHVDEEALAHARKVADRG
LEAHKAWDEKFDAWRKANPDKAALYDRLKAGELPEGFDKALDDLEATFEVGKNVATRGASGSVLNAIAAVMPELWGGSAD
LGGSNKTDLKGAATFAPAECATVQWPNCNEFGRQLHFGVREFAMGCITNGILLGSHTRPFGGTFFMFSDYERSAVRLAAL
MQIPNLYIWSHDSVAVGEDGPTHQPVEHLASFRAIPQLEVIRPADAFETAEAYRYFFEKKNTLPGAMILTRQGVPVLAET
AAKAKEGVRKGAYVLVDTEGTPDVILMASGSEVQWAVAAAKTLAGEGVKARVVSVPSLEWFEEQDAEYKEAVLPAAVKAR
VSVEAGVAMPWYKYLGSYGKPVSIEQFGLQGDGAQNMIDLGITAEHVVEAAKASIAEAEAAK

Sequences:

>Translated_702_residues
MTEFKETELDERAIKMAKVLSADAVEKAGSGHPGSPVSLAPVAYTLYQHFIKHDPNDPNWEGRDRFILSGGHASLTQYVQ
LYFSGYGVTLDDLKSFRGSAATRTPGHPEYGLTPGIEMTTGPLGQGLASAIGFAYGERFQRGLLDPETPKEDSPFYHKIW
AICGEGDIEEGISGEAASLAANQKLGNLTVIFDANRIQIEGDTNLVLAEDVLKRFQAYGWYTDEFSFIQPDGSYKEDIEG
LADVIAKAEKAAPDQPKLIKVHSLIAWPTPGKTNDPSSHGSKLGAEAVAGLKKLLGYDPEESFHVDEEALAHARKVADRG
LEAHKAWDEKFDAWRKANPDKAALYDRLKAGELPEGFDKALDDLEATFEVGKNVATRGASGSVLNAIAAVMPELWGGSAD
LGGSNKTDLKGAATFAPAECATVQWPNCNEFGRQLHFGVREFAMGCITNGILLGSHTRPFGGTFFMFSDYERSAVRLAAL
MQIPNLYIWSHDSVAVGEDGPTHQPVEHLASFRAIPQLEVIRPADAFETAEAYRYFFEKKNTLPGAMILTRQGVPVLAET
AAKAKEGVRKGAYVLVDTEGTPDVILMASGSEVQWAVAAAKTLAGEGVKARVVSVPSLEWFEEQDAEYKEAVLPAAVKAR
VSVEAGVAMPWYKYLGSYGKPVSIEQFGLQGDGAQNMIDLGITAEHVVEAAKASIAEAEAAK
>Mature_701_residues
TEFKETELDERAIKMAKVLSADAVEKAGSGHPGSPVSLAPVAYTLYQHFIKHDPNDPNWEGRDRFILSGGHASLTQYVQL
YFSGYGVTLDDLKSFRGSAATRTPGHPEYGLTPGIEMTTGPLGQGLASAIGFAYGERFQRGLLDPETPKEDSPFYHKIWA
ICGEGDIEEGISGEAASLAANQKLGNLTVIFDANRIQIEGDTNLVLAEDVLKRFQAYGWYTDEFSFIQPDGSYKEDIEGL
ADVIAKAEKAAPDQPKLIKVHSLIAWPTPGKTNDPSSHGSKLGAEAVAGLKKLLGYDPEESFHVDEEALAHARKVADRGL
EAHKAWDEKFDAWRKANPDKAALYDRLKAGELPEGFDKALDDLEATFEVGKNVATRGASGSVLNAIAAVMPELWGGSADL
GGSNKTDLKGAATFAPAECATVQWPNCNEFGRQLHFGVREFAMGCITNGILLGSHTRPFGGTFFMFSDYERSAVRLAALM
QIPNLYIWSHDSVAVGEDGPTHQPVEHLASFRAIPQLEVIRPADAFETAEAYRYFFEKKNTLPGAMILTRQGVPVLAETA
AKAKEGVRKGAYVLVDTEGTPDVILMASGSEVQWAVAAAKTLAGEGVKARVVSVPSLEWFEEQDAEYKEAVLPAAVKARV
SVEAGVAMPWYKYLGSYGKPVSIEQFGLQGDGAQNMIDLGITAEHVVEAAKASIAEAEAAK

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=611, Percent_Identity=25.3682487725041, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI4507521, Length=611, Percent_Identity=25.3682487725041, Blast_Score=130, Evalue=6e-30,
Organism=Homo sapiens, GI133778974, Length=279, Percent_Identity=28.673835125448, Blast_Score=91, Evalue=5e-18,
Organism=Escherichia coli, GI1788808, Length=681, Percent_Identity=41.5565345080764, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI48994911, Length=678, Percent_Identity=40.7079646017699, Blast_Score=479, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI17539652, Length=617, Percent_Identity=26.0940032414911, Blast_Score=128, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6325331, Length=700, Percent_Identity=41.2857142857143, Blast_Score=478, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6319593, Length=700, Percent_Identity=39.5714285714286, Blast_Score=448, Evalue=1e-126,
Organism=Drosophila melanogaster, GI45551847, Length=610, Percent_Identity=25.5737704918033, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45550715, Length=610, Percent_Identity=25.5737704918033, Blast_Score=121, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24666278, Length=603, Percent_Identity=25.5389718076285, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24645119, Length=567, Percent_Identity=25.9259259259259, Blast_Score=106, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 75790; Mature: 75659

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFKETELDERAIKMAKVLSADAVEKAGSGHPGSPVSLAPVAYTLYQHFIKHDPNDPNW
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
EGRDRFILSGGHASLTQYVQLYFSGYGVTLDDLKSFRGSAATRTPGHPEYGLTPGIEMTT
CCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GPLGQGLASAIGFAYGERFQRGLLDPETPKEDSPFYHKIWAICGEGDIEEGISGEAASLA
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEHHHHCCCCCCCCCCCCCHHHHH
ANQKLGNLTVIFDANRIQIEGDTNLVLAEDVLKRFQAYGWYTDEFSFIQPDGSYKEDIEG
HCCCCCCEEEEEECCEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHH
LADVIAKAEKAAPDQPKLIKVHSLIAWPTPGKTNDPSSHGSKLGAEAVAGLKKLLGYDPE
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ESFHVDEEALAHARKVADRGLEAHKAWDEKFDAWRKANPDKAALYDRLKAGELPEGFDKA
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHH
LDDLEATFEVGKNVATRGASGSVLNAIAAVMPELWGGSADLGGSNKTDLKGAATFAPAEC
HHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
ATVQWPNCNEFGRQLHFGVREFAMGCITNGILLGSHTRPFGGTFFMFSDYERSAVRLAAL
CEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEEECCHHHHHHHHHH
MQIPNLYIWSHDSVAVGEDGPTHQPVEHLASFRAIPQLEVIRPADAFETAEAYRYFFEKK
HHCCCEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHC
NTLPGAMILTRQGVPVLAETAAKAKEGVRKGAYVLVDTEGTPDVILMASGSEVQWAVAAA
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCEEHHHHHH
KTLAGEGVKARVVSVPSLEWFEEQDAEYKEAVLPAAVKARVSVEAGVAMPWYKYLGSYGK
HHHHCCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCCCC
PVSIEQFGLQGDGAQNMIDLGITAEHVVEAAKASIAEAEAAK
CCCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEFKETELDERAIKMAKVLSADAVEKAGSGHPGSPVSLAPVAYTLYQHFIKHDPNDPNW
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
EGRDRFILSGGHASLTQYVQLYFSGYGVTLDDLKSFRGSAATRTPGHPEYGLTPGIEMTT
CCCCEEEEECCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GPLGQGLASAIGFAYGERFQRGLLDPETPKEDSPFYHKIWAICGEGDIEEGISGEAASLA
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHEEHHHHCCCCCCCCCCCCCHHHHH
ANQKLGNLTVIFDANRIQIEGDTNLVLAEDVLKRFQAYGWYTDEFSFIQPDGSYKEDIEG
HCCCCCCEEEEEECCEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHH
LADVIAKAEKAAPDQPKLIKVHSLIAWPTPGKTNDPSSHGSKLGAEAVAGLKKLLGYDPE
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
ESFHVDEEALAHARKVADRGLEAHKAWDEKFDAWRKANPDKAALYDRLKAGELPEGFDKA
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHH
LDDLEATFEVGKNVATRGASGSVLNAIAAVMPELWGGSADLGGSNKTDLKGAATFAPAEC
HHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
ATVQWPNCNEFGRQLHFGVREFAMGCITNGILLGSHTRPFGGTFFMFSDYERSAVRLAAL
CEEECCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCEEEEEECCHHHHHHHHHH
MQIPNLYIWSHDSVAVGEDGPTHQPVEHLASFRAIPQLEVIRPADAFETAEAYRYFFEKK
HHCCCEEEECCCCEEECCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHC
NTLPGAMILTRQGVPVLAETAAKAKEGVRKGAYVLVDTEGTPDVILMASGSEVQWAVAAA
CCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCEEHHHHHH
KTLAGEGVKARVVSVPSLEWFEEQDAEYKEAVLPAAVKARVSVEAGVAMPWYKYLGSYGK
HHHHCCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHCCCCC
PVSIEQFGLQGDGAQNMIDLGITAEHVVEAAKASIAEAEAAK
CCCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]