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The map label for this gene is murC [H]

Identifier: 213691751

GI number: 213691751

Start: 1010741

End: 1012279

Strand: Direct

Name: murC [H]

Synonym: Blon_0857

Alternate gene names: 213691751

Gene position: 1010741-1012279 (Clockwise)

Preceding gene: 213691750

Following gene: 213691752

Centisome position: 35.68

GC content: 63.74

Gene sequence:

>1539_bases
TTGTCTCAAGATCAGCCCATCGTGCTTGACCCCACGTATGCCTCATTCGATGCTGCGGCCCGCCCCGCGGATCTCGGCGC
CACCCATTTCATCGGTATCGGCGGTGCCGGTATGAGCGTTCTGGCCGAAATGCTGCACGCCGAAGGAGTCTCGGTGGACG
GCTCCGATCGCTCACACAGCGCCAAAACCGACCGACTTGAAACGCTGGGCATCACCGTTGAATTCGGGCAGCGAGCCGAA
AATGTCGCCCAGGCCGAGACCGTGGTCTACTCCAGCGCCATCAAACCGGACAATCCGGAAATCGTCGCAGCGCACGCGGC
GGGCAAGCGCATTGTGCATCGCAGTGACATCCTCGCCCTGCTCATGAACGGCAAACGAGCCGTCACCGTGGCCGGAGCGC
ACGGCAAAACCACCACCAGCTCCATGCTGTCCCACATTCTGGTGAACGCCGGTGCCGATCCAAGCTACGCCATTGGCGGC
TTTATCCAAGGCCCGGACGGCACCACGCTGGACGGCGGACACGCGGGCAAAGGCGATATCCTGGTGGCCGAAGCCGATGA
ATCGGACGGCAGCTTCGCCAAATATCATCCGACCATCGCCATTATCACCAACTGTGAAGCCGATCATCTCGACCATTACG
GCGACGAAGCCCACTACCGTGCCGCGTTCGTTGCCCACGCCGGCCGGGCCACCGGTCACGTGATCATCAGCATCGACGAC
CCTGACGGACTTGCCGTGCTGGAGGCCATGCCCGCCGACGTGAAATCCCATACCGTTGCCTACGGCACTACCGCGCGTGA
ATCCCTGCCCGATTTGGGCGGTGCCGCGTATGTCTGGATCGCTTCGGAAAGTGAGACCGCAGGCAGCGGCGTCGAACAGC
TCACCCTGCATCTGCCGGCCGCGGTGACGGCGGGGGAGCCGGTGTCTCAGAGCGTTGCCCTGAAGGTTCCTGGCGTGCAC
AATGCGCGCAATGCGGCCGCCGCCATCAGCGCTGCCGTGCTGCTGGGCGTGAGCCCCGCAGACGCGGCCAAGGCGGCCGG
CACATTCCTCGGTGCGGCACGCCGTTTCCAGGTGCGCGGCACGGTCAAGCAGGTCACTGTAGTGGACGATTACGCCCACC
ATCCCACCGAAATCGCGGCCCTGCTGGATGCGGCCCGACGCCGGTACCCCGATTCGACCATTCGTGTGATCTTCCAGCCA
CACCTGTTCTCCCGCACCAAGTTCTTCGCGCACCAGTTCGCCGAATCCTTGGCCAAAGCCGATGACGTCATTATCACCGG
CATCTTCCCGGCCCGTGAAAAGCAGGCTGATTTCCCGGACATCAGCCCCTCCACCATCGTGGACGCGGCTGCGGGACTCA
AGGATGCTTCCGCAGGCACGTGGATTCAGCCGGTCGAGGATATGTGCCTGGCCGCCAAGATGATGGCCATGCGCGCCCAC
CACGGCGACGTGATCTTCACCGTGGGCGCGGGCGACATCACCGACATGGATCAGGTGCTGCTCACCGCACTTGAGGCCCA
TCGGGAAAGCTGCGAGTGA

Upstream 100 bases:

>100_bases
TATTCAGATATCATCCCGTGCGCGATACGGGCCAATCCCGTCCCGCAACACGAGATACGGTCATAATATAGGGTGCTGGA
ATCCCCAAAGGAGTTTTGAA

Downstream 100 bases:

>100_bases
TGTCCGGGCGCACGGTCAGATCCGGGGGCAATGACAACGGCTCACGTCGTTCGTCCGGAAGTCCCCGCAAGCCGCGCACC
ATCGGTTCACGCGGAAACAC

Product: UDP-N-acetylmuramate--alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MSQDQPIVLDPTYASFDAAARPADLGATHFIGIGGAGMSVLAEMLHAEGVSVDGSDRSHSAKTDRLETLGITVEFGQRAE
NVAQAETVVYSSAIKPDNPEIVAAHAAGKRIVHRSDILALLMNGKRAVTVAGAHGKTTTSSMLSHILVNAGADPSYAIGG
FIQGPDGTTLDGGHAGKGDILVAEADESDGSFAKYHPTIAIITNCEADHLDHYGDEAHYRAAFVAHAGRATGHVIISIDD
PDGLAVLEAMPADVKSHTVAYGTTARESLPDLGGAAYVWIASESETAGSGVEQLTLHLPAAVTAGEPVSQSVALKVPGVH
NARNAAAAISAAVLLGVSPADAAKAAGTFLGAARRFQVRGTVKQVTVVDDYAHHPTEIAALLDAARRRYPDSTIRVIFQP
HLFSRTKFFAHQFAESLAKADDVIITGIFPAREKQADFPDISPSTIVDAAAGLKDASAGTWIQPVEDMCLAAKMMAMRAH
HGDVIFTVGAGDITDMDQVLLTALEAHRESCE

Sequences:

>Translated_512_residues
MSQDQPIVLDPTYASFDAAARPADLGATHFIGIGGAGMSVLAEMLHAEGVSVDGSDRSHSAKTDRLETLGITVEFGQRAE
NVAQAETVVYSSAIKPDNPEIVAAHAAGKRIVHRSDILALLMNGKRAVTVAGAHGKTTTSSMLSHILVNAGADPSYAIGG
FIQGPDGTTLDGGHAGKGDILVAEADESDGSFAKYHPTIAIITNCEADHLDHYGDEAHYRAAFVAHAGRATGHVIISIDD
PDGLAVLEAMPADVKSHTVAYGTTARESLPDLGGAAYVWIASESETAGSGVEQLTLHLPAAVTAGEPVSQSVALKVPGVH
NARNAAAAISAAVLLGVSPADAAKAAGTFLGAARRFQVRGTVKQVTVVDDYAHHPTEIAALLDAARRRYPDSTIRVIFQP
HLFSRTKFFAHQFAESLAKADDVIITGIFPAREKQADFPDISPSTIVDAAAGLKDASAGTWIQPVEDMCLAAKMMAMRAH
HGDVIFTVGAGDITDMDQVLLTALEAHRESCE
>Mature_511_residues
SQDQPIVLDPTYASFDAAARPADLGATHFIGIGGAGMSVLAEMLHAEGVSVDGSDRSHSAKTDRLETLGITVEFGQRAEN
VAQAETVVYSSAIKPDNPEIVAAHAAGKRIVHRSDILALLMNGKRAVTVAGAHGKTTTSSMLSHILVNAGADPSYAIGGF
IQGPDGTTLDGGHAGKGDILVAEADESDGSFAKYHPTIAIITNCEADHLDHYGDEAHYRAAFVAHAGRATGHVIISIDDP
DGLAVLEAMPADVKSHTVAYGTTARESLPDLGGAAYVWIASESETAGSGVEQLTLHLPAAVTAGEPVSQSVALKVPGVHN
ARNAAAAISAAVLLGVSPADAAKAAGTFLGAARRFQVRGTVKQVTVVDDYAHHPTEIAALLDAARRRYPDSTIRVIFQPH
LFSRTKFFAHQFAESLAKADDVIITGIFPAREKQADFPDISPSTIVDAAAGLKDASAGTWIQPVEDMCLAAKMMAMRAHH
GDVIFTVGAGDITDMDQVLLTALEAHRESCE

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1786279, Length=481, Percent_Identity=37.006237006237, Blast_Score=219, Evalue=5e-58,
Organism=Escherichia coli, GI1790680, Length=505, Percent_Identity=29.7029702970297, Blast_Score=149, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 53449; Mature: 53318

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDQPIVLDPTYASFDAAARPADLGATHFIGIGGAGMSVLAEMLHAEGVSVDGSDRSHS
CCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
AKTDRLETLGITVEFGQRAENVAQAETVVYSSAIKPDNPEIVAAHAAGKRIVHRSDILAL
CCCCCEEEEEEEEECCHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCHHHHHHHHHHE
LMNGKRAVTVAGAHGKTTTSSMLSHILVNAGADPSYAIGGFIQGPDGTTLDGGHAGKGDI
EECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCEEECCCCCEECCCCCCCCCE
LVAEADESDGSFAKYHPTIAIITNCEADHLDHYGDEAHYRAAFVAHAGRATGHVIISIDD
EEEECCCCCCCEEEECCEEEEEECCCHHHHHCCCCCHHHEEEEEEECCCCCCEEEEEEEC
PDGLAVLEAMPADVKSHTVAYGTTARESLPDLGGAAYVWIASESETAGSGVEQLTLHLPA
CCCEEEEECCCCCHHCCEEEECCCHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEECCE
AVTAGEPVSQSVALKVPGVHNARNAAAAISAAVLLGVSPADAAKAAGTFLGAARRFQVRG
EECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHEEEEEC
TVKQVTVVDDYAHHPTEIAALLDAARRRYPDSTIRVIFQPHLFSRTKFFAHQFAESLAKA
CEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
DDVIITGIFPAREKQADFPDISPSTIVDAAAGLKDASAGTWIQPVEDMCLAAKMMAMRAH
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
HGDVIFTVGAGDITDMDQVLLTALEAHRESCE
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQDQPIVLDPTYASFDAAARPADLGATHFIGIGGAGMSVLAEMLHAEGVSVDGSDRSHS
CCCCCEEECCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
AKTDRLETLGITVEFGQRAENVAQAETVVYSSAIKPDNPEIVAAHAAGKRIVHRSDILAL
CCCCCEEEEEEEEECCHHHHHHHHHHHHHEECCCCCCCCCEEEEECCCCHHHHHHHHHHE
LMNGKRAVTVAGAHGKTTTSSMLSHILVNAGADPSYAIGGFIQGPDGTTLDGGHAGKGDI
EECCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEECCEEECCCCCEECCCCCCCCCE
LVAEADESDGSFAKYHPTIAIITNCEADHLDHYGDEAHYRAAFVAHAGRATGHVIISIDD
EEEECCCCCCCEEEECCEEEEEECCCHHHHHCCCCCHHHEEEEEEECCCCCCEEEEEEEC
PDGLAVLEAMPADVKSHTVAYGTTARESLPDLGGAAYVWIASESETAGSGVEQLTLHLPA
CCCEEEEECCCCCHHCCEEEECCCHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEECCE
AVTAGEPVSQSVALKVPGVHNARNAAAAISAAVLLGVSPADAAKAAGTFLGAARRFQVRG
EECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHEEEEEC
TVKQVTVVDDYAHHPTEIAALLDAARRRYPDSTIRVIFQPHLFSRTKFFAHQFAESLAKA
CEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
DDVIITGIFPAREKQADFPDISPSTIVDAAAGLKDASAGTWIQPVEDMCLAAKMMAMRAH
CCEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
HGDVIFTVGAGDITDMDQVLLTALEAHRESCE
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA