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The map label for this gene is regA [H]

Identifier: 213691684

GI number: 213691684

Start: 915743

End: 916783

Strand: Reverse

Name: regA [H]

Synonym: Blon_0789

Alternate gene names: 213691684

Gene position: 916783-915743 (Counterclockwise)

Preceding gene: 213691685

Following gene: 213691683

Centisome position: 32.36

GC content: 61.1

Gene sequence:

>1041_bases
ATGGCTACGATGAAGGAAATCGCGAACAAGGCGGGGGTTTCCGTCTCTACGGTGTCGCTGGTGCTCAACGGACGCGACGA
GGGGCGCGTAAAGTCCGAAATTGCGGACAATGTGCGCGCCATCGCCACCAAGCTCGGCTACCGGTCGAATCCGCTGGCCA
GTTCGCTGCGTACAGGCAAGACGCACATCCTCGGTTTCATCAGCGAGGAGGTGGCCACCACCCCGTACGCCGGCGGTATG
ATTCTGGGCGCGCAGACCGCCGCAAGCCAGTTCGGCTATATGCTCATCACCGTGATCACCGACGGTGAGAACAGCGAGAG
CGAGGAAATCGCCGCACTCAAGCGATACGGCACCGACGGTTTCCTGTACGCCAAGATGTCGAACCGCATCACCCATGTGC
CTTCTTCGCTAGCCAAGACGCCACTGGTGTTGGTGGATGCCACCGACTCGCTTGGCAAAATCCCGAGCGTCGAACCGAAC
GAGTTCCGAATCGGCTACGACGCCACCACCAGATTGATTAAGGCCGGATGCGCACGTATCGCCTATGTGGGTTGCTCGGA
GCCGATGATTGCGCAGGACGGTCGTTTGGAAGGCTATCAGGCGGCGCTCAGGGATGCCGGCCTCGACTATGACGATCATC
TGGTCGTCAATGTGCTCAACAGCGGGCCGGCACTGACCGCAGTCAGCGATTTGTTCGACGCCGAGCATCCGGACGGATTC
TTCTGCTTCAACGATGCCCGCGCCTGGTATGTGTACGAATGCGCCGCACGCCGAGGACTCACGGTCGGCAAGGACATCTC
CGTGGTCGGCGTGGACAACCATCGTGTGTTCGCCGAGACGCTGGAACCGATGCTCACCACTGTGGAACTGCCGCATTTCG
AGATGGGCTACTGGGCCGTGGCCAAGCTGGTGTCGATCATCGAAGGACGCTCGATGGACGACGTCTCACGGCCAGCGACC
ACCGCTCCCCTGCCGCCGATCGACGCGCCGATTCCGGCGAAGATCCACTGCACGCTGATCGAAAAGGCCTCGGTGAAGTA
G

Upstream 100 bases:

>100_bases
ATACCATTATTCATCGGTGCGGTGCGCAACCTCGGCGGAGTCGGTGGAGAAAACTGATGCTTTCCCAACAGTCCGTCAAT
TAGGGTGTATCGTTTGACGC

Downstream 100 bases:

>100_bases
CCGAGTCCCACACGATTTCTCAAGGCCTCCGTCCAGCACGGAGGCCTTTTTGCATGTCGAACGGGTACGACACGCCGATG
ACGTCAATCGATTGACGTAA

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MATMKEIANKAGVSVSTVSLVLNGRDEGRVKSEIADNVRAIATKLGYRSNPLASSLRTGKTHILGFISEEVATTPYAGGM
ILGAQTAASQFGYMLITVITDGENSESEEIAALKRYGTDGFLYAKMSNRITHVPSSLAKTPLVLVDATDSLGKIPSVEPN
EFRIGYDATTRLIKAGCARIAYVGCSEPMIAQDGRLEGYQAALRDAGLDYDDHLVVNVLNSGPALTAVSDLFDAEHPDGF
FCFNDARAWYVYECAARRGLTVGKDISVVGVDNHRVFAETLEPMLTTVELPHFEMGYWAVAKLVSIIEGRSMDDVSRPAT
TAPLPPIDAPIPAKIHCTLIEKASVK

Sequences:

>Translated_346_residues
MATMKEIANKAGVSVSTVSLVLNGRDEGRVKSEIADNVRAIATKLGYRSNPLASSLRTGKTHILGFISEEVATTPYAGGM
ILGAQTAASQFGYMLITVITDGENSESEEIAALKRYGTDGFLYAKMSNRITHVPSSLAKTPLVLVDATDSLGKIPSVEPN
EFRIGYDATTRLIKAGCARIAYVGCSEPMIAQDGRLEGYQAALRDAGLDYDDHLVVNVLNSGPALTAVSDLFDAEHPDGF
FCFNDARAWYVYECAARRGLTVGKDISVVGVDNHRVFAETLEPMLTTVELPHFEMGYWAVAKLVSIIEGRSMDDVSRPAT
TAPLPPIDAPIPAKIHCTLIEKASVK
>Mature_345_residues
ATMKEIANKAGVSVSTVSLVLNGRDEGRVKSEIADNVRAIATKLGYRSNPLASSLRTGKTHILGFISEEVATTPYAGGMI
LGAQTAASQFGYMLITVITDGENSESEEIAALKRYGTDGFLYAKMSNRITHVPSSLAKTPLVLVDATDSLGKIPSVEPNE
FRIGYDATTRLIKAGCARIAYVGCSEPMIAQDGRLEGYQAALRDAGLDYDDHLVVNVLNSGPALTAVSDLFDAEHPDGFF
CFNDARAWYVYECAARRGLTVGKDISVVGVDNHRVFAETLEPMLTTVELPHFEMGYWAVAKLVSIIEGRSMDDVSRPATT
APLPPIDAPIPAKIHCTLIEKASVK

Specific function: Involved in the regulation of amylase production [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=316, Percent_Identity=32.2784810126582, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1790369, Length=326, Percent_Identity=26.6871165644172, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1789068, Length=338, Percent_Identity=28.4023668639053, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787906, Length=274, Percent_Identity=27.7372262773723, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789202, Length=338, Percent_Identity=26.9230769230769, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787948, Length=353, Percent_Identity=25.7790368271955, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI48994940, Length=325, Percent_Identity=26.7692307692308, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789456, Length=302, Percent_Identity=26.4900662251656, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37205; Mature: 37074

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATMKEIANKAGVSVSTVSLVLNGRDEGRVKSEIADNVRAIATKLGYRSNPLASSLRTGK
CCCHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
THILGFISEEVATTPYAGGMILGAQTAASQFGYMLITVITDGENSESEEIAALKRYGTDG
HHEEEEHHHHHHCCCCCCCEEEECHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHCCCCC
FLYAKMSNRITHVPSSLAKTPLVLVDATDSLGKIPSVEPNEFRIGYDATTRLIKAGCARI
EEEEECCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHEE
AYVGCSEPMIAQDGRLEGYQAALRDAGLDYDDHLVVNVLNSGPALTAVSDLFDAEHPDGF
EEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCE
FCFNDARAWYVYECAARRGLTVGKDISVVGVDNHRVFAETLEPMLTTVELPHFEMGYWAV
EEECCCCEEEEEEEHHHCCCCCCCCEEEEECCCCEEHHHHHHHHHHEEECCCCCCHHHHH
AKLVSIIEGRSMDDVSRPATTAPLPPIDAPIPAKIHCTLIEKASVK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
ATMKEIANKAGVSVSTVSLVLNGRDEGRVKSEIADNVRAIATKLGYRSNPLASSLRTGK
CCHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
THILGFISEEVATTPYAGGMILGAQTAASQFGYMLITVITDGENSESEEIAALKRYGTDG
HHEEEEHHHHHHCCCCCCCEEEECHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHCCCCC
FLYAKMSNRITHVPSSLAKTPLVLVDATDSLGKIPSVEPNEFRIGYDATTRLIKAGCARI
EEEEECCCCCCCCCHHHHCCCEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHEE
AYVGCSEPMIAQDGRLEGYQAALRDAGLDYDDHLVVNVLNSGPALTAVSDLFDAEHPDGF
EEECCCCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCE
FCFNDARAWYVYECAARRGLTVGKDISVVGVDNHRVFAETLEPMLTTVELPHFEMGYWAV
EEECCCCEEEEEEEHHHCCCCCCCCEEEEECCCCEEHHHHHHHHHHEEECCCCCCHHHHH
AKLVSIIEGRSMDDVSRPATTAPLPPIDAPIPAKIHCTLIEKASVK
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]