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The map label for this gene is proC [H]

Identifier: 213691647

GI number: 213691647

Start: 871378

End: 872181

Strand: Reverse

Name: proC [H]

Synonym: Blon_0751

Alternate gene names: 213691647

Gene position: 872181-871378 (Counterclockwise)

Preceding gene: 213691659

Following gene: 213691646

Centisome position: 30.79

GC content: 60.95

Gene sequence:

>804_bases
ATGGGAGCGAACCTGTATTTCATCGGCGGAGGCAATATGCCGAGCGCCATCATAGAAGCGGTGCGACGTAAGGCCGCCGC
ATATCCGGTCGACCACATCTGGGTTGAGGAAATCTCACGGGAACGCGCCGAATATCTGGCATCCACGTACAACACCGAGA
CGGCGTCACCGACGGACGCCCCGGATGCCGACATCGTGGTAATCGCGGTGCGCCCGCAAGACGATGTCGCCGGCGTGGCC
GCTTCAGTGGCGCGACGTTTCGACCCGGCGAAGACCACGGTGATCTCCATCGTAGCCGGCTATACCATCGCCAAGCTTGA
GCAAGGGCTCGGCCATGGGTGGCGTGTGGCCCGCATCATCCCGAACACACTCACCACCGTGGATTACGGTTACAGCGGCG
TGGCGCTGAATGGGGCCGCGGCACGCGAGGACGTGGATGCGTTCCTCAACACTTTCGGCAAAGTACTGTATGTCGAGGAA
CGACTTATCGACGTAATCACCGGTTTTTACCCGCCGAACATCGTCTACCATTTCATCGACGCCTACGTGGATGCCGGTGT
GCTGGCCGGTCTGCCCCGGGACGCGGCCAGAGCCATCGCGCTCGACACCATCATCGGCGGCACCGAATTCCTCAAACAGA
AAGACGTGCTGCCTCAAGTGCTGCTCAATATCAACAACTCCCCCGGCGGAGTGGGAATCACCGAGGCATATACCCTGAAC
AAAACCGGATTCGCGGCATCCATACAATCCGCGGTGCTGGCGGCGGTCGAGCGCACCACGGCGCTCGGCGGCGATGCAAA
GTAA

Upstream 100 bases:

>100_bases
CCTATATGCCATTTCGGAAGGAACGACGACGGTTCGGGAATCCATGCGGTATTACGGGAACTGACATACATCCGTATCCA
TCATCAGAAGAGGTGAACCG

Downstream 100 bases:

>100_bases
AGACGGGAGCCGATCATGACGCAACAATTCACCTGGGACCATACGGTCGAATTCGTGAATGACCTCAAGTCCGCCGAACG
GACGTTCGCCGACGCAGGGC

Product: NADP oxidoreductase, coenzyme F420-dependent

Products: NA

Alternate protein names: P5C reductase; P5CR [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MGANLYFIGGGNMPSAIIEAVRRKAAAYPVDHIWVEEISRERAEYLASTYNTETASPTDAPDADIVVIAVRPQDDVAGVA
ASVARRFDPAKTTVISIVAGYTIAKLEQGLGHGWRVARIIPNTLTTVDYGYSGVALNGAAAREDVDAFLNTFGKVLYVEE
RLIDVITGFYPPNIVYHFIDAYVDAGVLAGLPRDAARAIALDTIIGGTEFLKQKDVLPQVLLNINNSPGGVGITEAYTLN
KTGFAASIQSAVLAAVERTTALGGDAK

Sequences:

>Translated_267_residues
MGANLYFIGGGNMPSAIIEAVRRKAAAYPVDHIWVEEISRERAEYLASTYNTETASPTDAPDADIVVIAVRPQDDVAGVA
ASVARRFDPAKTTVISIVAGYTIAKLEQGLGHGWRVARIIPNTLTTVDYGYSGVALNGAAAREDVDAFLNTFGKVLYVEE
RLIDVITGFYPPNIVYHFIDAYVDAGVLAGLPRDAARAIALDTIIGGTEFLKQKDVLPQVLLNINNSPGGVGITEAYTLN
KTGFAASIQSAVLAAVERTTALGGDAK
>Mature_266_residues
GANLYFIGGGNMPSAIIEAVRRKAAAYPVDHIWVEEISRERAEYLASTYNTETASPTDAPDADIVVIAVRPQDDVAGVAA
SVARRFDPAKTTVISIVAGYTIAKLEQGLGHGWRVARIIPNTLTTVDYGYSGVALNGAAAREDVDAFLNTFGKVLYVEER
LIDVITGFYPPNIVYHFIDAYVDAGVLAGLPRDAARAIALDTIIGGTEFLKQKDVLPQVLLNINNSPGGVGITEAYTLNK
TGFAASIQSAVLAAVERTTALGGDAK

Specific function: Proline biosynthesis; third (last) step. [C]

COG id: COG0345

COG function: function code E; Pyrroline-5-carboxylate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyrroline-5-carboxylate reductase family [H]

Homologues:

Organism=Homo sapiens, GI24797097, Length=227, Percent_Identity=30.3964757709251, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI24797095, Length=227, Percent_Identity=30.3964757709251, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI198041662, Length=265, Percent_Identity=26.7924528301887, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI21361454, Length=214, Percent_Identity=30.3738317757009, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1786585, Length=272, Percent_Identity=29.7794117647059, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17569021, Length=269, Percent_Identity=30.4832713754647, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24648116, Length=274, Percent_Identity=30.2919708029197, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21358587, Length=271, Percent_Identity=27.6752767527675, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647700, Length=173, Percent_Identity=29.4797687861272, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR016040
- InterPro:   IPR004455
- InterPro:   IPR000304 [H]

Pfam domain/function: PF03807 F420_oxidored [H]

EC number: =1.5.1.2 [H]

Molecular weight: Translated: 28329; Mature: 28198

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGANLYFIGGGNMPSAIIEAVRRKAAAYPVDHIWVEEISRERAEYLASTYNTETASPTDA
CCCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PDADIVVIAVRPQDDVAGVAASVARRFDPAKTTVISIVAGYTIAKLEQGLGHGWRVARII
CCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PNTLTTVDYGYSGVALNGAAAREDVDAFLNTFGKVLYVEERLIDVITGFYPPNIVYHFID
CCHHHEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AYVDAGVLAGLPRDAARAIALDTIIGGTEFLKQKDVLPQVLLNINNSPGGVGITEAYTLN
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
KTGFAASIQSAVLAAVERTTALGGDAK
CCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GANLYFIGGGNMPSAIIEAVRRKAAAYPVDHIWVEEISRERAEYLASTYNTETASPTDA
CCEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PDADIVVIAVRPQDDVAGVAASVARRFDPAKTTVISIVAGYTIAKLEQGLGHGWRVARII
CCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
PNTLTTVDYGYSGVALNGAAAREDVDAFLNTFGKVLYVEERLIDVITGFYPPNIVYHFID
CCHHHEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AYVDAGVLAGLPRDAARAIALDTIIGGTEFLKQKDVLPQVLLNINNSPGGVGITEAYTLN
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
KTGFAASIQSAVLAAVERTTALGGDAK
CCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]