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The map label for this gene is hisS

Identifier: 213691601

GI number: 213691601

Start: 811351

End: 812751

Strand: Direct

Name: hisS

Synonym: Blon_0705

Alternate gene names: 213691601

Gene position: 811351-812751 (Clockwise)

Preceding gene: 213691599

Following gene: 213691602

Centisome position: 28.64

GC content: 63.17

Gene sequence:

>1401_bases
GTGGCTAAAGGTGCATCAATATCAGGATTCCCGGAGTGGCTCCCCTCCGAACGTGTTGTGGAGCAGCGTGTTATCGATAC
GCTTCGTAAGGTTTTTGAGCTCAACGGCTTCATCGGCATTGAGACGCGAGCGGTGGAAACCGGCGCTTCTTTGTTGAAAA
AAGGCGAGACCAGCAAGGAGATCTACCTGCTGAGCCGTTTGCAGGAGGTCGGTCATGAATCCGACACTCCGATTGAAGAG
CGGTTGGGCCTGCATTTCGATCTGACCGTGCCGCTGAGCCGGTATGTGGTCGAGCACTCGGGTGCGTTGGCGTTCCCGTT
CAAGCGCTGGCAGATTCAGAAGGTGTGGCGTGGCGAGCGTCCGCAGGAAGGCCGCTTCCGCGAGTTCGTGCAGGCCGATA
TCGACGTGATCGGTGCCGGCGACCTGCCCGACCACTATGAAGTGGAACTGCCGCTGGTCATGGTCTCCGCGCTGGAAGAG
CTGCGCGCGTATGGCCTCCCCAAGGCCACCGTGCACGCCAATAACCGCAAGTTGTCTGAAGGCTTCTACCGCGGCCTTGG
CCTGACGGACGTCGAAGGCGTGCTGCGCGAGATCGACAAGCTCGACAAAATCGGTGCCGATGAGGTGGCCCGACTGCTCA
CCGAGACCTGCGGCGCCACCGAAGCACAGGCACGCGCCTGCCTCGAATTGGCCGAGCTCACCGCCTCCGACGGTGCTGAG
CTTGCCGCCAAGTTCGATGCGCTGTGCGAGTCTCACGGCATCGCCAAGGATTCCGAGGCATACACGCTGGCTCGTCAGGG
ACTTGATACCCTGGCCATGATCGTCGACGAGGCCGCCGCCATCCGCCCCGGTTCCGTCATCGCCGACCTGAAGATCGCCC
GCGGTCTCGACTACTACACCGGTTCCGTCTACGAGACCTTCCTCGACGGTGCCGCATCACTCGGTTCCATCTGTTCCGGT
GGCCGTTACGACAATCTCGCCTCCCAGGGCAACCGCAAGTACCCGGGCGTGGGCCTGTCCATCGGCCTGAGCCGACTGGT
CAGCTACATGCTGCACGCTGCCGGCGCGCACGCCAACCGCGTCAGCCCGGCCGCCGTGCTGGTCGCTGTGTGGAATGAAG
AGGACCGCCCGGCCGCCAACCGTATTGCGAACCAACTGCGTGCGCGCGGCATCGCCACCGACGTGGCACCCACCGCGGCC
AAGCTCGGCAAGCAGATCAAGTACGCGGACAAACTCGGCATTCCGTACGTGTGGTTCCCGGCCACCGCTGCCGAAGGTGC
GGAAGGCGCAGAGCCCGCTGGCGACGAGGTCAAGAACATCGTCACGGGCGAGCAGGTTGCCGCCGATTGCACGTCGTGGG
AGCCGGATACTGTGGTTGCCCAGCAAACCGTCGAAATCTGA

Upstream 100 bases:

>100_bases
TGGCCAGCTCCTTAAAGCGTAGAATGCATAAGCGGGAGCGTCTCCCATCCCGGGCGAACCAGGAAGTTTTGACGCAACCC
TCACCTATTATATTGATTTC

Downstream 100 bases:

>100_bases
CGTATTCGCGCGAAAAATCGAGGAGAAACAAGACAATGAGCCAGACGGCTTACAGAACACATCATGCCACTGAAGTGACC
GAGGCCCTGGTCGGCCAGAA

Product: histidyl-tRNA synthetase

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MAKGASISGFPEWLPSERVVEQRVIDTLRKVFELNGFIGIETRAVETGASLLKKGETSKEIYLLSRLQEVGHESDTPIEE
RLGLHFDLTVPLSRYVVEHSGALAFPFKRWQIQKVWRGERPQEGRFREFVQADIDVIGAGDLPDHYEVELPLVMVSALEE
LRAYGLPKATVHANNRKLSEGFYRGLGLTDVEGVLREIDKLDKIGADEVARLLTETCGATEAQARACLELAELTASDGAE
LAAKFDALCESHGIAKDSEAYTLARQGLDTLAMIVDEAAAIRPGSVIADLKIARGLDYYTGSVYETFLDGAASLGSICSG
GRYDNLASQGNRKYPGVGLSIGLSRLVSYMLHAAGAHANRVSPAAVLVAVWNEEDRPAANRIANQLRARGIATDVAPTAA
KLGKQIKYADKLGIPYVWFPATAAEGAEGAEPAGDEVKNIVTGEQVAADCTSWEPDTVVAQQTVEI

Sequences:

>Translated_466_residues
MAKGASISGFPEWLPSERVVEQRVIDTLRKVFELNGFIGIETRAVETGASLLKKGETSKEIYLLSRLQEVGHESDTPIEE
RLGLHFDLTVPLSRYVVEHSGALAFPFKRWQIQKVWRGERPQEGRFREFVQADIDVIGAGDLPDHYEVELPLVMVSALEE
LRAYGLPKATVHANNRKLSEGFYRGLGLTDVEGVLREIDKLDKIGADEVARLLTETCGATEAQARACLELAELTASDGAE
LAAKFDALCESHGIAKDSEAYTLARQGLDTLAMIVDEAAAIRPGSVIADLKIARGLDYYTGSVYETFLDGAASLGSICSG
GRYDNLASQGNRKYPGVGLSIGLSRLVSYMLHAAGAHANRVSPAAVLVAVWNEEDRPAANRIANQLRARGIATDVAPTAA
KLGKQIKYADKLGIPYVWFPATAAEGAEGAEPAGDEVKNIVTGEQVAADCTSWEPDTVVAQQTVEI
>Mature_465_residues
AKGASISGFPEWLPSERVVEQRVIDTLRKVFELNGFIGIETRAVETGASLLKKGETSKEIYLLSRLQEVGHESDTPIEER
LGLHFDLTVPLSRYVVEHSGALAFPFKRWQIQKVWRGERPQEGRFREFVQADIDVIGAGDLPDHYEVELPLVMVSALEEL
RAYGLPKATVHANNRKLSEGFYRGLGLTDVEGVLREIDKLDKIGADEVARLLTETCGATEAQARACLELAELTASDGAEL
AAKFDALCESHGIAKDSEAYTLARQGLDTLAMIVDEAAAIRPGSVIADLKIARGLDYYTGSVYETFLDGAASLGSICSGG
RYDNLASQGNRKYPGVGLSIGLSRLVSYMLHAAGAHANRVSPAAVLVAVWNEEDRPAANRIANQLRARGIATDVAPTAAK
LGKQIKYADKLGIPYVWFPATAAEGAEGAEPAGDEVKNIVTGEQVAADCTSWEPDTVVAQQTVEI

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI6996014, Length=432, Percent_Identity=28.4722222222222, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI15029520, Length=427, Percent_Identity=28.1030444964871, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1788861, Length=468, Percent_Identity=27.5641025641026, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71993686, Length=438, Percent_Identity=28.310502283105, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71993693, Length=438, Percent_Identity=28.310502283105, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6325290, Length=454, Percent_Identity=30.1762114537445, Blast_Score=142, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24643061, Length=445, Percent_Identity=28.9887640449438, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24643059, Length=463, Percent_Identity=28.0777537796976, Blast_Score=122, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYH_BIFLI (B7GPS9)

Other databases:

- EMBL:   CP001095
- RefSeq:   YP_002322187.1
- GeneID:   7053784
- GenomeReviews:   CP001095_GR
- KEGG:   bln:Blon_0705
- HOGENOM:   HBG616575
- ProtClustDB:   PRK00037
- GO:   GO:0005737
- HAMAP:   MF_00127
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516
- Gene3D:   G3DSA:3.40.50.800
- PANTHER:   PTHR11476
- PIRSF:   PIRSF001549
- TIGRFAMs:   TIGR00442

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b; SSF52954 Anticodon_bd

EC number: =6.1.1.21

Molecular weight: Translated: 50352; Mature: 50221

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGASISGFPEWLPSERVVEQRVIDTLRKVFELNGFIGIETRAVETGASLLKKGETSKE
CCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCHH
IYLLSRLQEVGHESDTPIEERLGLHFDLTVPLSRYVVEHSGALAFPFKRWQIQKVWRGER
HHHHHHHHHHCCCCCCCHHHHCCCEEEEECCHHHHHHHCCCCEECCHHHHHHHHHHCCCC
PQEGRFREFVQADIDVIGAGDLPDHYEVELPLVMVSALEELRAYGLPKATVHANNRKLSE
CCCCHHHHHHHHCCCEEECCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCHHH
GFYRGLGLTDVEGVLREIDKLDKIGADEVARLLTETCGATEAQARACLELAELTASDGAE
HHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHH
LAAKFDALCESHGIAKDSEAYTLARQGLDTLAMIVDEAAAIRPGSVIADLKIARGLDYYT
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHH
GSVYETFLDGAASLGSICSGGRYDNLASQGNRKYPGVGLSIGLSRLVSYMLHAAGAHANR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
VSPAAVLVAVWNEEDRPAANRIANQLRARGIATDVAPTAAKLGKQIKYADKLGIPYVWFP
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHCCCCEEEEC
ATAAEGAEGAEPAGDEVKNIVTGEQVAADCTSWEPDTVVAQQTVEI
CCCCCCCCCCCCCCHHHHHHHCHHHHHHHCCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
AKGASISGFPEWLPSERVVEQRVIDTLRKVFELNGFIGIETRAVETGASLLKKGETSKE
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCHH
IYLLSRLQEVGHESDTPIEERLGLHFDLTVPLSRYVVEHSGALAFPFKRWQIQKVWRGER
HHHHHHHHHHCCCCCCCHHHHCCCEEEEECCHHHHHHHCCCCEECCHHHHHHHHHHCCCC
PQEGRFREFVQADIDVIGAGDLPDHYEVELPLVMVSALEELRAYGLPKATVHANNRKLSE
CCCCHHHHHHHHCCCEEECCCCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCCCCHHH
GFYRGLGLTDVEGVLREIDKLDKIGADEVARLLTETCGATEAQARACLELAELTASDGAE
HHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHH
LAAKFDALCESHGIAKDSEAYTLARQGLDTLAMIVDEAAAIRPGSVIADLKIARGLDYYT
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHH
GSVYETFLDGAASLGSICSGGRYDNLASQGNRKYPGVGLSIGLSRLVSYMLHAAGAHANR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
VSPAAVLVAVWNEEDRPAANRIANQLRARGIATDVAPTAAKLGKQIKYADKLGIPYVWFP
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHCCCCEEEEC
ATAAEGAEGAEPAGDEVKNIVTGEQVAADCTSWEPDTVVAQQTVEI
CCCCCCCCCCCCCCHHHHHHHCHHHHHHHCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA