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The map label for this gene is 213691545

Identifier: 213691545

GI number: 213691545

Start: 742898

End: 745180

Strand: Reverse

Name: 213691545

Synonym: Blon_0646

Alternate gene names: NA

Gene position: 745180-742898 (Counterclockwise)

Preceding gene: 213691551

Following gene: 213691523

Centisome position: 26.31

GC content: 65.18

Gene sequence:

>2283_bases
ATGGCAGCATCCAACCCGATCAGCTGGTCACAGCGAACATTCCCCTCACCCGAAGGCACGATCGCGTGCAGATTCCGCGC
ACACGCGGACGGCCGCATCTTCGATGCCGTCAATGGATCGGCGAATGACGCGCCGCTCCTCATATGCGCCATCGAACATG
ACGCTCTGCGCGTGCGCGCGACGACGCCACGACAGCACGTCGATTTCGACATCGAGGACACGACGGGGATAGCCGACGGC
GCCATGCACACGTTCGCGCTCACATTCGGCGAGTTCGGCACGCGCGTCTACCTCGACGGCTCCCAGTGCTTCAGCGGCAC
GGCGAACCTGTGCCCCACGACGCTCACCGGAACCGAGGGGTCAGGCCAAGGCGCGATTCGCCTCGCGGGCCCGTCCATCG
ACGTGACCGACATGCGTCTGCATGCAATCCCCCTCACCTCCGAAAGCATCGCCGCCTTGACGCCGAGACCCGCACCGGAC
ATCGACTTCGCCGCGGCCCAGCTCGCCCCGCGAGATGTGCGCCGCGTGCGCACGCTACGTTCCGGCACGATCTTCATGCA
TTTTCGTGTGCGCGGACCCCGCCAGTACGGCACGCTTCTCGCCGCCGGCGAGCGCGGCGAGGAACGCCTCGCCGTCTCGA
TCGACGACAACGGCATCACGATGACGGCCGCGGATGGCCTGTATGAGCCATCCACCTACCATGCGCGCGGCGCATGGGAT
GACGGCCGATGGCATGATCTGTCGATTCGTTCCGCGCGTGGCGCCATCGACATGTACGTCGACGGCTGGCACGAACTGCA
TCAAGCGGGACAGGTGTTCTTCGGCGACTGGCCGCAACTGGATGAGGTGGCCATCGGGCAGAACACGGAAGGCGTCAGGC
TCATGGGCGAGGTGCGCAACGGCGGCGTCTTCACGACCCCGCTCACCGACGGCGCGATCCGCAGGCTTTCGGACGCACCG
GCGCTAACGACGACCGCACTGTTCGACAAGGGTTACCACGGATCCGTGAGTTATCGCATCCCCTCGATCATCCGCACCCC
TCATGGCGTGGTCGTCGCCGGCGCCGACCAGCGCACCGCGATTGCGAATGACGCGCCGAACCACATCAACTTCGTCATGC
GCAGGTCGCTTGACGGTGGCCGCACCTGGCTCGACATGCAGACCGTGATCGCCAATCCGGGCGAAGGCGTCGACGGCGCG
TGCACAATCGACTCATGTCTTGTATGCGACGAACGCAATGGCCGTCTCACCGTCCTCATCGACCGCTTCGCCGGCGGCGT
CGGGTTGCCGAACAACACGCCCGGCACCGGGGTCGACCGGCACGGGCGACCGTGCCTGTACGATCGCGCAGGCACACGCT
ATGTACTCGCCGATGACGGCACGGTGCTTGACGGCGGCGGCGAGCGCACCGGATACCGGGTCGACGCGCACGGCAACGTG
ACGCACGAGGGACGGGCCTCGGGCAACATCTACCTCAAGGAGGGCGCTGACCCCGACGAATCACTGCTCATCGAACGCAC
GAGCTTCATCATCGAACTGCATTCCGACGATGACGGCGAGACGTGGAGCACACCACGCAACATCAACCACATGATCAAGG
AGGATTGGATGCACTTCCTGGGCGTCTCGCCCGGCAACGGCATCCAGCTCCAGGCCTCCGAACATCGCGGGCGTCTGCTC
GTCCCGTTCTACTGCACCGGCGCCTCACTCAAGCATTACTCGGGCGGAGCGCTCATCAGCGACGATGGCGGCGACACATG
GCGACGTGGTTCGATGATCAACGACGGCCGCATCGTCAACGGCACCGCCGTCGACCCGAAGAACATCCGGGACGATGACG
CGACCACGCACGAATCCGTGTTCGTCGAGCGCGCGGATGGCACCGTCGTGTGCTTCTTCCGCAACCAGAACCATGCCGGG
CGCATCGGCGTCGCGCTCAGCCACGACGGCGGCGAGACATGGGATGACCTGTACTTCGACAAAGACGTCCCCGACATCTT
CTGCCAACCGAACGCCGTGGCCTGCGCGCCGCGATCGGACACGATGGTGTTCGCGAACGCAAGCCAGATGCTGCCGTATC
GCGGCAACGGGGTGCTGCGGCTGAGTCTGGACGGCGCACGCACATGGGCGGCGCATCGCTGCATCAACCCCTATCATTAC
GGCTATCAGTGCATGACGATGCTGCCGGACGGCGAACTCGGATTACTCTGGGAGCGCGAGACCGCGGGATTGTACTTCAC
CACGCTGCCGTTGAGCGTATTCGGCGCGGCCGAAACGCACTGA

Upstream 100 bases:

>100_bases
CAGACGTCTGATGTTTCCCGTTGGTTGGATACCATGACTTCAGATGTCCCATTCATGGCACGGCATATATACGGGCCCGC
TCAAAGGAGAGTCATTGACC

Downstream 100 bases:

>100_bases
GGGCGTGTTCGGGAACACGTGTGCGACGCATGTTCCCGAACATGCCCCCACCGGCCGTTAATGGTCGAGCCGGGCGGCGA
ACCAGCGCGTGATCGACGTC

Product: glycosyl hydrolase, BNR repeat-containing protein

Products: NA

Alternate protein names: Neuraminidase [H]

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MAASNPISWSQRTFPSPEGTIACRFRAHADGRIFDAVNGSANDAPLLICAIEHDALRVRATTPRQHVDFDIEDTTGIADG
AMHTFALTFGEFGTRVYLDGSQCFSGTANLCPTTLTGTEGSGQGAIRLAGPSIDVTDMRLHAIPLTSESIAALTPRPAPD
IDFAAAQLAPRDVRRVRTLRSGTIFMHFRVRGPRQYGTLLAAGERGEERLAVSIDDNGITMTAADGLYEPSTYHARGAWD
DGRWHDLSIRSARGAIDMYVDGWHELHQAGQVFFGDWPQLDEVAIGQNTEGVRLMGEVRNGGVFTTPLTDGAIRRLSDAP
ALTTTALFDKGYHGSVSYRIPSIIRTPHGVVVAGADQRTAIANDAPNHINFVMRRSLDGGRTWLDMQTVIANPGEGVDGA
CTIDSCLVCDERNGRLTVLIDRFAGGVGLPNNTPGTGVDRHGRPCLYDRAGTRYVLADDGTVLDGGGERTGYRVDAHGNV
THEGRASGNIYLKEGADPDESLLIERTSFIIELHSDDDGETWSTPRNINHMIKEDWMHFLGVSPGNGIQLQASEHRGRLL
VPFYCTGASLKHYSGGALISDDGGDTWRRGSMINDGRIVNGTAVDPKNIRDDDATTHESVFVERADGTVVCFFRNQNHAG
RIGVALSHDGGETWDDLYFDKDVPDIFCQPNAVACAPRSDTMVFANASQMLPYRGNGVLRLSLDGARTWAAHRCINPYHY
GYQCMTMLPDGELGLLWERETAGLYFTTLPLSVFGAAETH

Sequences:

>Translated_760_residues
MAASNPISWSQRTFPSPEGTIACRFRAHADGRIFDAVNGSANDAPLLICAIEHDALRVRATTPRQHVDFDIEDTTGIADG
AMHTFALTFGEFGTRVYLDGSQCFSGTANLCPTTLTGTEGSGQGAIRLAGPSIDVTDMRLHAIPLTSESIAALTPRPAPD
IDFAAAQLAPRDVRRVRTLRSGTIFMHFRVRGPRQYGTLLAAGERGEERLAVSIDDNGITMTAADGLYEPSTYHARGAWD
DGRWHDLSIRSARGAIDMYVDGWHELHQAGQVFFGDWPQLDEVAIGQNTEGVRLMGEVRNGGVFTTPLTDGAIRRLSDAP
ALTTTALFDKGYHGSVSYRIPSIIRTPHGVVVAGADQRTAIANDAPNHINFVMRRSLDGGRTWLDMQTVIANPGEGVDGA
CTIDSCLVCDERNGRLTVLIDRFAGGVGLPNNTPGTGVDRHGRPCLYDRAGTRYVLADDGTVLDGGGERTGYRVDAHGNV
THEGRASGNIYLKEGADPDESLLIERTSFIIELHSDDDGETWSTPRNINHMIKEDWMHFLGVSPGNGIQLQASEHRGRLL
VPFYCTGASLKHYSGGALISDDGGDTWRRGSMINDGRIVNGTAVDPKNIRDDDATTHESVFVERADGTVVCFFRNQNHAG
RIGVALSHDGGETWDDLYFDKDVPDIFCQPNAVACAPRSDTMVFANASQMLPYRGNGVLRLSLDGARTWAAHRCINPYHY
GYQCMTMLPDGELGLLWERETAGLYFTTLPLSVFGAAETH
>Mature_759_residues
AASNPISWSQRTFPSPEGTIACRFRAHADGRIFDAVNGSANDAPLLICAIEHDALRVRATTPRQHVDFDIEDTTGIADGA
MHTFALTFGEFGTRVYLDGSQCFSGTANLCPTTLTGTEGSGQGAIRLAGPSIDVTDMRLHAIPLTSESIAALTPRPAPDI
DFAAAQLAPRDVRRVRTLRSGTIFMHFRVRGPRQYGTLLAAGERGEERLAVSIDDNGITMTAADGLYEPSTYHARGAWDD
GRWHDLSIRSARGAIDMYVDGWHELHQAGQVFFGDWPQLDEVAIGQNTEGVRLMGEVRNGGVFTTPLTDGAIRRLSDAPA
LTTTALFDKGYHGSVSYRIPSIIRTPHGVVVAGADQRTAIANDAPNHINFVMRRSLDGGRTWLDMQTVIANPGEGVDGAC
TIDSCLVCDERNGRLTVLIDRFAGGVGLPNNTPGTGVDRHGRPCLYDRAGTRYVLADDGTVLDGGGERTGYRVDAHGNVT
HEGRASGNIYLKEGADPDESLLIERTSFIIELHSDDDGETWSTPRNINHMIKEDWMHFLGVSPGNGIQLQASEHRGRLLV
PFYCTGASLKHYSGGALISDDGGDTWRRGSMINDGRIVNGTAVDPKNIRDDDATTHESVFVERADGTVVCFFRNQNHAGR
IGVALSHDGGETWDDLYFDKDVPDIFCQPNAVACAPRSDTMVFANASQMLPYRGNGVLRLSLDGARTWAAHRCINPYHYG
YQCMTMLPDGELGLLWERETAGLYFTTLPLSVFGAAETH

Specific function: Sialidases have been suggested to be pathogenic factors in microbial infections [H]

COG id: COG4409

COG function: function code G; Neuraminidase (sialidase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 F5/8 type C domain [H]

Homologues:

Organism=Homo sapiens, GI4557791, Length=240, Percent_Identity=32.0833333333333, Blast_Score=73, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002860
- InterPro:   IPR000421
- InterPro:   IPR008985
- InterPro:   IPR013320
- InterPro:   IPR008979
- InterPro:   IPR004124
- InterPro:   IPR011040 [H]

Pfam domain/function: PF02012 BNR; PF00754 F5_F8_type_C; PF02973 Sialidase [H]

EC number: =3.2.1.18 [H]

Molecular weight: Translated: 82563; Mature: 82432

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASNPISWSQRTFPSPEGTIACRFRAHADGRIFDAVNGSANDAPLLICAIEHDALRVRA
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCEEEEEE
TTPRQHVDFDIEDTTGIADGAMHTFALTFGEFGTRVYLDGSQCFSGTANLCPTTLTGTEG
CCCHHHEEEEECCCCCCCCCCEEEEEEEECCCCCEEEEECHHHCCCCCCCCCCEEECCCC
SGQGAIRLAGPSIDVTDMRLHAIPLTSESIAALTPRPAPDIDFAAAQLAPRDVRRVRTLR
CCCEEEEEECCCCCEECEEEEEEECCCCCCEEECCCCCCCCCHHHHHCCHHHHHHHHHHC
SGTIFMHFRVRGPRQYGTLLAAGERGEERLAVSIDDNGITMTAADGLYEPSTYHARGAWD
CCEEEEEEEECCCHHHCEEEEECCCCCCEEEEEECCCCEEEEECCCCCCCCCEECCCCCC
DGRWHDLSIRSARGAIDMYVDGWHELHQAGQVFFGDWPQLDEVAIGQNTEGVRLMGEVRN
CCCEEEEEEECCCCEEEEEECCHHHHHHCCCEEECCCCCCCCEEECCCCCCEEEEEEECC
GGVFTTPLTDGAIRRLSDAPALTTTALFDKGYHGSVSYRIPSIIRTPHGVVVAGADQRTA
CCEEEECCCCHHHHHHCCCCCEEEEEHHCCCCCCEEEEECCHHHCCCCCEEEECCCCCEE
IANDAPNHINFVMRRSLDGGRTWLDMQTVIANPGEGVDGACTIDSCLVCDERNGRLTVLI
ECCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCEEEECEEEEEECCCCEEEEEE
DRFAGGVGLPNNTPGTGVDRHGRPCLYDRAGTRYVLADDGTVLDGGGERTGYRVDAHGNV
EECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCEEECCCCCCCCEEEECCCCC
THEGRASGNIYLKEGADPDESLLIERTSFIIELHSDDDGETWSTPRNINHMIKEDWMHFL
CCCCCCCCCEEEECCCCCCHHEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
GVSPGNGIQLQASEHRGRLLVPFYCTGASLKHYSGGALISDDGGDTWRRGSMINDGRIVN
CCCCCCCEEEEECCCCCCEEEEEEECCCCEEECCCCEEEECCCCCCCCCCCCCCCCEEEE
GTAVDPKNIRDDDATTHESVFVERADGTVVCFFRNQNHAGRIGVALSHDGGETWDDLYFD
CCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCEEEEEEECCCCCCHHHCEEC
KDVPDIFCQPNAVACAPRSDTMVFANASQMLPYRGNGVLRLSLDGARTWAAHRCINPYHY
CCCCCEEECCCEEEECCCCCEEEEECCCCCCEECCCCEEEEEECCCCHHHHHHCCCCCCC
GYQCMTMLPDGELGLLWERETAGLYFTTLPLSVFGAAETH
CEEEEEECCCCCEEEEEEECCCCEEEEEECEEEECCCCCC
>Mature Secondary Structure 
AASNPISWSQRTFPSPEGTIACRFRAHADGRIFDAVNGSANDAPLLICAIEHDALRVRA
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCEEEEEECCCEEEEEE
TTPRQHVDFDIEDTTGIADGAMHTFALTFGEFGTRVYLDGSQCFSGTANLCPTTLTGTEG
CCCHHHEEEEECCCCCCCCCCEEEEEEEECCCCCEEEEECHHHCCCCCCCCCCEEECCCC
SGQGAIRLAGPSIDVTDMRLHAIPLTSESIAALTPRPAPDIDFAAAQLAPRDVRRVRTLR
CCCEEEEEECCCCCEECEEEEEEECCCCCCEEECCCCCCCCCHHHHHCCHHHHHHHHHHC
SGTIFMHFRVRGPRQYGTLLAAGERGEERLAVSIDDNGITMTAADGLYEPSTYHARGAWD
CCEEEEEEEECCCHHHCEEEEECCCCCCEEEEEECCCCEEEEECCCCCCCCCEECCCCCC
DGRWHDLSIRSARGAIDMYVDGWHELHQAGQVFFGDWPQLDEVAIGQNTEGVRLMGEVRN
CCCEEEEEEECCCCEEEEEECCHHHHHHCCCEEECCCCCCCCEEECCCCCCEEEEEEECC
GGVFTTPLTDGAIRRLSDAPALTTTALFDKGYHGSVSYRIPSIIRTPHGVVVAGADQRTA
CCEEEECCCCHHHHHHCCCCCEEEEEHHCCCCCCEEEEECCHHHCCCCCEEEECCCCCEE
IANDAPNHINFVMRRSLDGGRTWLDMQTVIANPGEGVDGACTIDSCLVCDERNGRLTVLI
ECCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCEEEECEEEEEECCCCEEEEEE
DRFAGGVGLPNNTPGTGVDRHGRPCLYDRAGTRYVLADDGTVLDGGGERTGYRVDAHGNV
EECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEECCCEEECCCCCCCCEEEECCCCC
THEGRASGNIYLKEGADPDESLLIERTSFIIELHSDDDGETWSTPRNINHMIKEDWMHFL
CCCCCCCCCEEEECCCCCCHHEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
GVSPGNGIQLQASEHRGRLLVPFYCTGASLKHYSGGALISDDGGDTWRRGSMINDGRIVN
CCCCCCCEEEEECCCCCCEEEEEEECCCCEEECCCCEEEECCCCCCCCCCCCCCCCEEEE
GTAVDPKNIRDDDATTHESVFVERADGTVVCFFRNQNHAGRIGVALSHDGGETWDDLYFD
CCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCEEEEEEECCCCCCHHHCEEC
KDVPDIFCQPNAVACAPRSDTMVFANASQMLPYRGNGVLRLSLDGARTWAAHRCINPYHY
CCCCCEEECCCEEEECCCCCEEEEECCCCCCEECCCCEEEEEECCCCHHHHHHCCCCCCC
GYQCMTMLPDGELGLLWERETAGLYFTTLPLSVFGAAETH
CEEEEEECCCCCEEEEEEECCCCEEEEEECEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2034213 [H]