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The map label for this gene is ccpA [H]

Identifier: 213691536

GI number: 213691536

Start: 732986

End: 734026

Strand: Direct

Name: ccpA [H]

Synonym: Blon_0637

Alternate gene names: 213691536

Gene position: 732986-734026 (Clockwise)

Preceding gene: 213691535

Following gene: 213691537

Centisome position: 25.88

GC content: 54.95

Gene sequence:

>1041_bases
ATGGCGTTCGTGACGTTGAAGGATGTTGCTCAACGTGCCGGTGTGTCGGCTGCTGCTGTTTCCCAGATACTTCACAATAA
AGGCCGCTTTTCTAGCGATACGCGACAGTTGGTGCTGAAAACTGTTGAGGAAATGGGGTATGTGCCCGATCAACGTGCTC
GCTCCATGCGCTCGTCGGATACTAAGACTGTTGGCCTGCTGGTTCCTGATTTGCGCAATCCGTATTTCGCCGATCTGGTT
GCTTCGATGGAGGATGAACTCTACCGGCATGGGGTCTCCACTCTGATTGGCACGTCTTCGGAAAGCGTGGAACGCCAGGA
TGTGTTTATCGAGAATCTTTTGGGCCAACGTATTGATGGGGCTATCGTCGTACCGCAGGGTGTGAAATCCCCCGGAGTGC
AATCGTTGATACAACGAGACTTGCCGTTGGTGTTCGTTGATCGTCGCGTTCCCGGTGTCGAGTCGGTGCCGTTTGTGGTT
TCTGATCCATATACGGGAATTCGTGAGGCTCTTGAAGAACTGGTGCGTCTGGGCCATCGACATGTGGGCTATATGTCTCA
TCCTTCGCTCGAATCGTTCAGTATTGACGAACGAGAGACCGCATTTCGGGAAGCTGCCGCCGATGTGCTTGCTGACGGCG
ATGGCGTTGTCGCAGCTTGCGACTCCACTTATGAATCGCGTGCCGCTGCGGTAGAGATGCTGCTGGGTGCAGGGGTGAGC
GCAATATTGTGCGCATATTCGCCGGATGCGTTCACGGTGATTGGACTGCTGCATGACCGCGGGGTGGCGATTGGCGAACG
CATGTCGTTGGTGTCGTTCGATGATATTTCGGCGTTTACCGTGATGACGCCGCGCATCGCCGTGATTTCCCAACAGGCGG
ATTTGATGGGGAAGCAGGGTGTGGAGCTATTGCTGCAACTCATCCGTTCGGGATCCATGGATGGCGGCATCACGCATTCC
GTGCCCACGATGTTCATCAAACGCGAATCTGTGGGTGAGGTTAGTTCCGCGTCCGTCGCCAATCAATCAGCGGAAGTGTG
A

Upstream 100 bases:

>100_bases
GTTGAGAGCCGTGTGTTGGCGCAGGATTACGAATATTGGCGGTGAAAAGAGTACATTTGAATTGTTGCTTTGACGATGTA
TCGGCCGCAAGGAGGGGACT

Downstream 100 bases:

>100_bases
TTCAAGCGGCTTCGAGAGGAATGCGCGGATACCTTTGACGCGCAGGTAGATGAGGCATTGACAATAGTGATTTAACGTCT
TATCATCAAATAAGCTGATG

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MAFVTLKDVAQRAGVSAAAVSQILHNKGRFSSDTRQLVLKTVEEMGYVPDQRARSMRSSDTKTVGLLVPDLRNPYFADLV
ASMEDELYRHGVSTLIGTSSESVERQDVFIENLLGQRIDGAIVVPQGVKSPGVQSLIQRDLPLVFVDRRVPGVESVPFVV
SDPYTGIREALEELVRLGHRHVGYMSHPSLESFSIDERETAFREAAADVLADGDGVVAACDSTYESRAAAVEMLLGAGVS
AILCAYSPDAFTVIGLLHDRGVAIGERMSLVSFDDISAFTVMTPRIAVISQQADLMGKQGVELLLQLIRSGSMDGGITHS
VPTMFIKRESVGEVSSASVANQSAEV

Sequences:

>Translated_346_residues
MAFVTLKDVAQRAGVSAAAVSQILHNKGRFSSDTRQLVLKTVEEMGYVPDQRARSMRSSDTKTVGLLVPDLRNPYFADLV
ASMEDELYRHGVSTLIGTSSESVERQDVFIENLLGQRIDGAIVVPQGVKSPGVQSLIQRDLPLVFVDRRVPGVESVPFVV
SDPYTGIREALEELVRLGHRHVGYMSHPSLESFSIDERETAFREAAADVLADGDGVVAACDSTYESRAAAVEMLLGAGVS
AILCAYSPDAFTVIGLLHDRGVAIGERMSLVSFDDISAFTVMTPRIAVISQQADLMGKQGVELLLQLIRSGSMDGGITHS
VPTMFIKRESVGEVSSASVANQSAEV
>Mature_345_residues
AFVTLKDVAQRAGVSAAAVSQILHNKGRFSSDTRQLVLKTVEEMGYVPDQRARSMRSSDTKTVGLLVPDLRNPYFADLVA
SMEDELYRHGVSTLIGTSSESVERQDVFIENLLGQRIDGAIVVPQGVKSPGVQSLIQRDLPLVFVDRRVPGVESVPFVVS
DPYTGIREALEELVRLGHRHVGYMSHPSLESFSIDERETAFREAAADVLADGDGVVAACDSTYESRAAAVEMLLGAGVSA
ILCAYSPDAFTVIGLLHDRGVAIGERMSLVSFDDISAFTVMTPRIAVISQQADLMGKQGVELLLQLIRSGSMDGGITHSV
PTMFIKRESVGEVSSASVANQSAEV

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788474, Length=347, Percent_Identity=28.2420749279539, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=28.4280936454849, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1790369, Length=320, Percent_Identity=28.4375, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1787948, Length=309, Percent_Identity=26.537216828479, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789068, Length=342, Percent_Identity=29.5321637426901, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790194, Length=315, Percent_Identity=25.3968253968254, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=24.6875, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786540, Length=340, Percent_Identity=25.8823529411765, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787906, Length=291, Percent_Identity=27.4914089347079, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787580, Length=327, Percent_Identity=22.6299694189602, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790715, Length=330, Percent_Identity=23.030303030303, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786268, Length=233, Percent_Identity=28.755364806867, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790689, Length=199, Percent_Identity=26.1306532663317, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37244; Mature: 37113

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFVTLKDVAQRAGVSAAAVSQILHNKGRFSSDTRQLVLKTVEEMGYVPDQRARSMRSSD
CCEEEHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
TKTVGLLVPDLRNPYFADLVASMEDELYRHGVSTLIGTSSESVERQDVFIENLLGQRIDG
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
AIVVPQGVKSPGVQSLIQRDLPLVFVDRRVPGVESVPFVVSDPYTGIREALEELVRLGHR
EEECCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHH
HVGYMSHPSLESFSIDERETAFREAAADVLADGDGVVAACDSTYESRAAAVEMLLGAGVS
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCHH
AILCAYSPDAFTVIGLLHDRGVAIGERMSLVSFDDISAFTVMTPRIAVISQQADLMGKQG
HEEEECCCCCEEEEEHHHCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
VELLLQLIRSGSMDGGITHSVPTMFIKRESVGEVSSASVANQSAEV
HHHHHHHHHCCCCCCCCCCCCHHHHEEHHCCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
AFVTLKDVAQRAGVSAAAVSQILHNKGRFSSDTRQLVLKTVEEMGYVPDQRARSMRSSD
CEEEHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
TKTVGLLVPDLRNPYFADLVASMEDELYRHGVSTLIGTSSESVERQDVFIENLLGQRIDG
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCC
AIVVPQGVKSPGVQSLIQRDLPLVFVDRRVPGVESVPFVVSDPYTGIREALEELVRLGHR
EEECCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHH
HVGYMSHPSLESFSIDERETAFREAAADVLADGDGVVAACDSTYESRAAAVEMLLGAGVS
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCHH
AILCAYSPDAFTVIGLLHDRGVAIGERMSLVSFDDISAFTVMTPRIAVISQQADLMGKQG
HEEEECCCCCEEEEEHHHCCCCCCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
VELLLQLIRSGSMDGGITHSVPTMFIKRESVGEVSSASVANQSAEV
HHHHHHHHHCCCCCCCCCCCCHHHHEEHHCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]