Click here to switch to the map view.

The map label for this gene is dac [H]

Identifier: 213691451

GI number: 213691451

Start: 616440

End: 617930

Strand: Direct

Name: dac [H]

Synonym: Blon_0546

Alternate gene names: 213691451

Gene position: 616440-617930 (Clockwise)

Preceding gene: 213691450

Following gene: 213691452

Centisome position: 21.76

GC content: 61.3

Gene sequence:

>1491_bases
ATGGTATCTACAGCGGTATCACGCCGTCAGCGACGTGAAGCGCAACGGCGGCCCCAACAATCGCATCGCCGAACACTGAC
CGTCATCATTTCCGCACTGACCACCATCGCCCTGTTCGCGGGGTACTGCGCCGCCGACATCACCGACGTGGCCCCCGGAT
TATTGACGTTGAAGCCCGTCACCGCACCTGTTTTTGCCGATCCAGCCACCGCCAAATCAGGCGGCACCGTCGCCGGCACC
TTGAACACGAACAAGGCCATTGATTCCACGGCCGCTTCTGCGCTGGTCAACGAATTGCTGTCCGCGCAAGGCGTGGGAAA
CGATACGTCGGTGATCATTGAAGACGCCCAAGGCACCGTCGCCGCCGAACACGAGTCGAACACTCCACGCGAGCCTGCAT
CCACACTGAAAACGCTGACCGCGCTCGCCGCCTCATCCACCCTGAATATGGCATCCACCTTGGATACCCAAGTGTTCCTC
ACCCAATCCGATGACGGCACCAATACGTTGACCCTCAAAGGCAATGGCGACATGCTGCTGTCTGCAGGCGATTCCGACGC
CAACCATACCAACGGACGTGCCGGTCTGAACACCTTGGCCAAGGCCACCGTGGCCGCGCTCGCCCAGCGAGGCATCACTT
CCGTCAATCTCGAGTACGACGACACCCTATTCGGCGACTCACGCATTCCCGCAGGTCTGTCGGAAGGTGGCGCGGTTTTA
AGCGACTACACCGTCTACTTCACGCCGGTCTCATCAATGGCGATTGATGGAGGCCGCCAACACACCGCCGATACGCCTGC
GCCGGCCGACCCCGATGATTCGGCCGGCTACCCGGAACTGTCCCAGCACACCGCCAGCGACGTGGCCACGAAATTCGCCG
AACTGCTCCAATCGAACGGTGTGGCCGTTACCGGAGACGTGACGGCAAACACCGCTCCATCCGGCGAAACGCCTTTGGCT
TCGGTGAGTTCGGCAACACTGTCCGAAATCATGGCATACACGTTACGGCATTCGGACAATACGCTGGCCGAGGAGTTCGG
CAGACTCACCGCTTTGGCGAAATCAGCGACAAACAGTCCTGAAGGCGGCACGGAGGCGGTCAAATCCACTCTGAACGATC
TCGGTCTCGATACATCCGGTCTGACCATGGCCGATTGCTCCGGTCTGTCTCCCGGCTCCCGGCTCACCGTACGCACGCTG
GCGGCCGTCCAACAACGTAATCTGACCACCAAGAGTGGCGCGGCCGGCGCGGAAGGTCTATCCATCGCGGGATTGGTGGG
CACGGCGCAGGATCGGTATACGGATGATGCCGTGGCTGGTCTGCTGCGCGTCAAAACCGGCAGCCTCGGCACGGTTGCGT
CGATGGCCGGCAATGTGTCCCGCACCAATGGGGGAGCGTTGTCGTTTGCCGTGGTGGTCAACAATCCTGAGGATTATGCC
GCCGCGCGTAGCGCCATCGACTCGTTCATCACCAAGCTCGCGGGGCTGTGA

Upstream 100 bases:

>100_bases
CTGGGCGGTAAGCTGATGGATGCGCGAATGCTCTCGATTGTGGCAACACTCGACTCGTTCGCCTCATTGCAGAAATGATT
GCCTTGGCATAAGGAGCACG

Downstream 100 bases:

>100_bases
AAGACCCATCAAGTGCCATCAAAGGCTACAAAGGCCGTAAACGTCCATAAACGCACGAGTACACATAACCAGAAAAAGGG
TGGTGAGTACATGGCATATT

Product: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein; PBP [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MVSTAVSRRQRREAQRRPQQSHRRTLTVIISALTTIALFAGYCAADITDVAPGLLTLKPVTAPVFADPATAKSGGTVAGT
LNTNKAIDSTAASALVNELLSAQGVGNDTSVIIEDAQGTVAAEHESNTPREPASTLKTLTALAASSTLNMASTLDTQVFL
TQSDDGTNTLTLKGNGDMLLSAGDSDANHTNGRAGLNTLAKATVAALAQRGITSVNLEYDDTLFGDSRIPAGLSEGGAVL
SDYTVYFTPVSSMAIDGGRQHTADTPAPADPDDSAGYPELSQHTASDVATKFAELLQSNGVAVTGDVTANTAPSGETPLA
SVSSATLSEIMAYTLRHSDNTLAEEFGRLTALAKSATNSPEGGTEAVKSTLNDLGLDTSGLTMADCSGLSPGSRLTVRTL
AAVQQRNLTTKSGAAGAEGLSIAGLVGTAQDRYTDDAVAGLLRVKTGSLGTVASMAGNVSRTNGGALSFAVVVNNPEDYA
AARSAIDSFITKLAGL

Sequences:

>Translated_496_residues
MVSTAVSRRQRREAQRRPQQSHRRTLTVIISALTTIALFAGYCAADITDVAPGLLTLKPVTAPVFADPATAKSGGTVAGT
LNTNKAIDSTAASALVNELLSAQGVGNDTSVIIEDAQGTVAAEHESNTPREPASTLKTLTALAASSTLNMASTLDTQVFL
TQSDDGTNTLTLKGNGDMLLSAGDSDANHTNGRAGLNTLAKATVAALAQRGITSVNLEYDDTLFGDSRIPAGLSEGGAVL
SDYTVYFTPVSSMAIDGGRQHTADTPAPADPDDSAGYPELSQHTASDVATKFAELLQSNGVAVTGDVTANTAPSGETPLA
SVSSATLSEIMAYTLRHSDNTLAEEFGRLTALAKSATNSPEGGTEAVKSTLNDLGLDTSGLTMADCSGLSPGSRLTVRTL
AAVQQRNLTTKSGAAGAEGLSIAGLVGTAQDRYTDDAVAGLLRVKTGSLGTVASMAGNVSRTNGGALSFAVVVNNPEDYA
AARSAIDSFITKLAGL
>Mature_496_residues
MVSTAVSRRQRREAQRRPQQSHRRTLTVIISALTTIALFAGYCAADITDVAPGLLTLKPVTAPVFADPATAKSGGTVAGT
LNTNKAIDSTAASALVNELLSAQGVGNDTSVIIEDAQGTVAAEHESNTPREPASTLKTLTALAASSTLNMASTLDTQVFL
TQSDDGTNTLTLKGNGDMLLSAGDSDANHTNGRAGLNTLAKATVAALAQRGITSVNLEYDDTLFGDSRIPAGLSEGGAVL
SDYTVYFTPVSSMAIDGGRQHTADTPAPADPDDSAGYPELSQHTASDVATKFAELLQSNGVAVTGDVTANTAPSGETPLA
SVSSATLSEIMAYTLRHSDNTLAEEFGRLTALAKSATNSPEGGTEAVKSTLNDLGLDTSGLTMADCSGLSPGSRLTVRTL
AAVQQRNLTTKSGAAGAEGLSIAGLVGTAQDRYTDDAVAGLLRVKTGSLGTVASMAGNVSRTNGGALSFAVVVNNPEDYA
AARSAIDSFITKLAGL

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG2027

COG function: function code M; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S13 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR000667 [H]

Pfam domain/function: PF02113 Peptidase_S13 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 50513; Mature: 50513

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTAVSRRQRREAQRRPQQSHRRTLTVIISALTTIALFAGYCAADITDVAPGLLTLKPV
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
TAPVFADPATAKSGGTVAGTLNTNKAIDSTAASALVNELLSAQGVGNDTSVIIEDAQGTV
CCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCE
AAEHESNTPREPASTLKTLTALAASSTLNMASTLDTQVFLTQSDDGTNTLTLKGNGDMLL
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCEEE
SAGDSDANHTNGRAGLNTLAKATVAALAQRGITSVNLEYDDTLFGDSRIPAGLSEGGAVL
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCEE
SDYTVYFTPVSSMAIDGGRQHTADTPAPADPDDSAGYPELSQHTASDVATKFAELLQSNG
ECCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VAVTGDVTANTAPSGETPLASVSSATLSEIMAYTLRHSDNTLAEEFGRLTALAKSATNSP
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
EGGTEAVKSTLNDLGLDTSGLTMADCSGLSPGSRLTVRTLAAVQQRNLTTKSGAAGAEGL
CCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
SIAGLVGTAQDRYTDDAVAGLLRVKTGSLGTVASMAGNVSRTNGGALSFAVVVNNPEDYA
EEEEEEECCHHHCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEECCHHHH
AARSAIDSFITKLAGL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSTAVSRRQRREAQRRPQQSHRRTLTVIISALTTIALFAGYCAADITDVAPGLLTLKPV
CCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
TAPVFADPATAKSGGTVAGTLNTNKAIDSTAASALVNELLSAQGVGNDTSVIIEDAQGTV
CCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCE
AAEHESNTPREPASTLKTLTALAASSTLNMASTLDTQVFLTQSDDGTNTLTLKGNGDMLL
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCEEE
SAGDSDANHTNGRAGLNTLAKATVAALAQRGITSVNLEYDDTLFGDSRIPAGLSEGGAVL
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCEE
SDYTVYFTPVSSMAIDGGRQHTADTPAPADPDDSAGYPELSQHTASDVATKFAELLQSNG
ECCEEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
VAVTGDVTANTAPSGETPLASVSSATLSEIMAYTLRHSDNTLAEEFGRLTALAKSATNSP
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
EGGTEAVKSTLNDLGLDTSGLTMADCSGLSPGSRLTVRTLAAVQQRNLTTKSGAAGAEGL
CCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
SIAGLVGTAQDRYTDDAVAGLLRVKTGSLGTVASMAGNVSRTNGGALSFAVVVNNPEDYA
EEEEEEECCHHHCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEECCHHHH
AARSAIDSFITKLAGL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1554361; 7305936 [H]