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The map label for this gene is ycnB [H]

Identifier: 213691354

GI number: 213691354

Start: 513492

End: 515081

Strand: Reverse

Name: ycnB [H]

Synonym: Blon_0445

Alternate gene names: 213691354

Gene position: 515081-513492 (Counterclockwise)

Preceding gene: 213691355

Following gene: 213691350

Centisome position: 18.18

GC content: 60.44

Gene sequence:

>1590_bases
GTGGCTGGAGAGAACGGAATCAAGAACCGTCGTGGCGAACTGCAACGAGTGCTGAGCCAAGAGGAATCATACGTTGACGG
CAAGCTGAGTCATGCCGCGTTTGTTTCCATCGCAATCCTGACCTTTATTACCTTCGTCGGCAACTTTACGCAGCTGCAGC
TGAGCTCGGCGCTGCCAATCATCGTTTCGGAATTCCATATTTCCGTAACCACGGGCCAGTGGCTGACCTCCGTGTTCCAG
CTGGTCATGGGCGTTATGGTACCGCTGACCGCGTTCCTGACCCGTCGTTTCTCCACCCGACAGATCGTGATCTGCTCGAT
GGCGGTGTTCACGATCGGCTCCCTGCTGGCCTGGCTGGGCCCGAACTTCCTCTTCGTGCTGCTCGGCCGCGTGCTGGAGG
CGGCCGGCACGGGCGTGATGTGGCCGGTGCTGCAGATCACGGTGTTCTCGATCTACCCGCTGTCCCGACGCGGCTTTGCT
ATGGGCACCGTGGGCATGGCCATGAGCGTGGCTCCGGCAATCGGCCCCACCTTGGGCGGCTGGCAGACCGACGTCAATGG
CTGGCGTTCCATCTTCCTGACCATGACCGTGATTGGCGTGGTCTCGCTGGTGGCGGCCATGTTCGGACTACATAATTTCG
GCTCGCATGACCCGTCTGCCCGCGCGGACTTTTTCTCGGTGAGCCTGTCGGTGATTGGCTTTGGCGGGCTGATGTTCGGC
TTCACCAATTCGGAGGCCTACGGGTTCGCCGCACCGGTAACGTGGGGGCCCATGGCAGTGGGCCTGATTGGCATTGTCTG
GTTCGTGCTGCGTAACCTGCGCGCTGGCAAGCGGTATCGCGAGGCCGTAGCCGAGGACAAGTCGGCACTCCCCCAGCCGC
CGCTGCTGGACTTGGAAGTGCTGAAGAACCGTTCGTTCACCATCGGCACCATTACCGCGTCGCTGGCATTTTTCGCGTTC
AGTTCGATTCTGGTCATCATGCCGCTCTATATCCAGACCGACCGTGGGTATTCTGCCACGATGAGTGGTCTGATCATGCT
GCCGGGCGCTATCGGTCAGTGCATCTCCCAGTTCTTCGGCGGCCGTGCGATGGATCGATTCGGCGCACGACCCGTGGCTT
TGTTCGGTTCGATTGTGTTGACCCTTGGCACCTTGGGCATGTCGCTGGTGGCGATGGATACGTGGATCTGGTGGGTATCG
ATCTGCCAGTTCATCCGTCAGATCGGCATGGGTTTCCTGCTGATGCCGATTACCACGTGGTCACTGAATTGCCTGAACGG
GCCGAGCGAAGTGTCCGCCGGATCATCGGTGACGAATACCGCGCGTCAGATTGCGGGCGCTGTGGGCGCACCCGTGTTGG
TGATTCTGATGGAAACGTTTGCCGCTTTGCATAAGCGGGGCGGCGCCTCCGCCGTCGCCGCTTCGATTTTTGGCATTCAA
TGGGCGCTGCGCATCTCCGCAATGATCTGTCTGGTAATGGTGTTGATGGTGTTCTTCGGCGTCAAGGGCGACGGTGCCGG
TCGTACGCGAGACATTATTTCCTTGCGCGCGCTGCGCGAACGGCGTGCGCGGCGTATGGCTGCGAACTGA

Upstream 100 bases:

>100_bases
AAACCAGCATACCGGCACGCGCCGCAGGCACAACCAGTGCCGAACATGCCAACCGACACCGCCCAAAGCCATCAGGCCGA
GCAACGGAAGTGGAGTGTGC

Downstream 100 bases:

>100_bases
CGGCAGATTCAACCATTCTTAACATAATAAGAAGCCCCGGTTTCCAACACCGGGGCTTCTTATTATGTTGTGCTATCGCA
GGATTTCAGCTGGAGTCTAT

Product: drug resistance transporter, EmrB/QacA subfamily

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MAGENGIKNRRGELQRVLSQEESYVDGKLSHAAFVSIAILTFITFVGNFTQLQLSSALPIIVSEFHISVTTGQWLTSVFQ
LVMGVMVPLTAFLTRRFSTRQIVICSMAVFTIGSLLAWLGPNFLFVLLGRVLEAAGTGVMWPVLQITVFSIYPLSRRGFA
MGTVGMAMSVAPAIGPTLGGWQTDVNGWRSIFLTMTVIGVVSLVAAMFGLHNFGSHDPSARADFFSVSLSVIGFGGLMFG
FTNSEAYGFAAPVTWGPMAVGLIGIVWFVLRNLRAGKRYREAVAEDKSALPQPPLLDLEVLKNRSFTIGTITASLAFFAF
SSILVIMPLYIQTDRGYSATMSGLIMLPGAIGQCISQFFGGRAMDRFGARPVALFGSIVLTLGTLGMSLVAMDTWIWWVS
ICQFIRQIGMGFLLMPITTWSLNCLNGPSEVSAGSSVTNTARQIAGAVGAPVLVILMETFAALHKRGGASAVAASIFGIQ
WALRISAMICLVMVLMVFFGVKGDGAGRTRDIISLRALRERRARRMAAN

Sequences:

>Translated_529_residues
MAGENGIKNRRGELQRVLSQEESYVDGKLSHAAFVSIAILTFITFVGNFTQLQLSSALPIIVSEFHISVTTGQWLTSVFQ
LVMGVMVPLTAFLTRRFSTRQIVICSMAVFTIGSLLAWLGPNFLFVLLGRVLEAAGTGVMWPVLQITVFSIYPLSRRGFA
MGTVGMAMSVAPAIGPTLGGWQTDVNGWRSIFLTMTVIGVVSLVAAMFGLHNFGSHDPSARADFFSVSLSVIGFGGLMFG
FTNSEAYGFAAPVTWGPMAVGLIGIVWFVLRNLRAGKRYREAVAEDKSALPQPPLLDLEVLKNRSFTIGTITASLAFFAF
SSILVIMPLYIQTDRGYSATMSGLIMLPGAIGQCISQFFGGRAMDRFGARPVALFGSIVLTLGTLGMSLVAMDTWIWWVS
ICQFIRQIGMGFLLMPITTWSLNCLNGPSEVSAGSSVTNTARQIAGAVGAPVLVILMETFAALHKRGGASAVAASIFGIQ
WALRISAMICLVMVLMVFFGVKGDGAGRTRDIISLRALRERRARRMAAN
>Mature_528_residues
AGENGIKNRRGELQRVLSQEESYVDGKLSHAAFVSIAILTFITFVGNFTQLQLSSALPIIVSEFHISVTTGQWLTSVFQL
VMGVMVPLTAFLTRRFSTRQIVICSMAVFTIGSLLAWLGPNFLFVLLGRVLEAAGTGVMWPVLQITVFSIYPLSRRGFAM
GTVGMAMSVAPAIGPTLGGWQTDVNGWRSIFLTMTVIGVVSLVAAMFGLHNFGSHDPSARADFFSVSLSVIGFGGLMFGF
TNSEAYGFAAPVTWGPMAVGLIGIVWFVLRNLRAGKRYREAVAEDKSALPQPPLLDLEVLKNRSFTIGTITASLAFFAFS
SILVIMPLYIQTDRGYSATMSGLIMLPGAIGQCISQFFGGRAMDRFGARPVALFGSIVLTLGTLGMSLVAMDTWIWWVSI
CQFIRQIGMGFLLMPITTWSLNCLNGPSEVSAGSSVTNTARQIAGAVGAPVLVILMETFAALHKRGGASAVAASIFGIQW
ALRISAMICLVMVLMVFFGVKGDGAGRTRDIISLRALRERRARRMAAN

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=455, Percent_Identity=25.2747252747253, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790195, Length=411, Percent_Identity=25.0608272506083, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1788710, Length=433, Percent_Identity=24.9422632794457, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081983, Length=412, Percent_Identity=24.7572815533981, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788392, Length=428, Percent_Identity=24.2990654205607, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787947, Length=170, Percent_Identity=27.6470588235294, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 57014; Mature: 56883

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGENGIKNRRGELQRVLSQEESYVDGKLSHAAFVSIAILTFITFVGNFTQLQLSSALPI
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCE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HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]