Click here to switch to the map view.

The map label for this gene is pgi [H]

Identifier: 213691330

GI number: 213691330

Start: 480064

End: 481761

Strand: Direct

Name: pgi [H]

Synonym: Blon_0417

Alternate gene names: 213691330

Gene position: 480064-481761 (Clockwise)

Preceding gene: 213691328

Following gene: 213691333

Centisome position: 16.95

GC content: 64.08

Gene sequence:

>1698_bases
ATGGCCATCAATCCGCCCGTTGACGCCACCCAGACCCCTGAGTGGGCTGCCCTGCAGAAGCACTATGACGAGCTTCAGGC
CGAAGGCGTGAGCCTCAAGAAGTGGTTCGCCGAGGACGCCGAGCGCGTCGAGAAGCTGTCCTTCGACGCCGGCGACCTGC
ACTTCGATCTGTCCAAGAACCTGATCAAGCCGGAAACCCTCCAGCTGTTCGCCGACCTTGCCAAGGCCGTCAAGCTCGAT
GAGCGCACCAAGGCTATGTACACCGGTGTGCACATCAACAACACCGAAGATCGCGCCGTGCTGCACACCGCGCTGCGCCG
CCCGGTCGAGGATGAAGGCAAGTACATCGTCGACGGCCAGGACACCGTCAAGGACGTGCGCGAGGTGCTCGACCGCATCT
ACGCCTTCGCCGACAAGGTCCGTTCCGGCGAGTGGACCGGTGTGACCGGCAAGAAGATCGAGACCGTGGTCAACATCGGC
ATCGGCGGCTCCGACCTGGGCCCCGTCATGGTGTACGAAGCCCTCAAGCCGTACGCCGACGCCGGCATCTCCGCCCGCTA
CATCTCCAACATCGACCCGAACGACCTGGCCGAGAAGACCAAGGGCCTCGACCCGGAGACCACCCTGTTCATCATCGTTT
CCAAGACCTTCACCACCCTGGAGACCCTGACCAACGCCCGTGAAGCCCGCACCTGGCTGCTCGAAGAGCTCAAGGCCAAG
GGCGCCATCGACGGCTCCGACGAGAAGAACGCCGAAGCCATCAAGAAGCACTTCGTCGCCGTCTCCACCAACCTGGAGAA
GGTCGCCGAATTCGGCATCGACCCGAACAACGCGTTCGGCTTCTGGAACTGGGTCGGCGGCCGTTACTCCGTCGACTCCG
CCGTCGGCACCTCCCTGGCCGTGGTCTTCGGCCCGGCTCGTTTCGAGGAGTTCCTGCACGGCTTCCACGAGATCGATGAG
TACTTCGCCAACACCCCGTTCGAGAAGAACGTCGTGGTGCTGCTCGGTATGCTGAACGTCTGGTACCGCAACTTCTTCAA
GGTCGCCTCCCACGCCGTGCTGCCGTACGACCAGTATCTGCACCGCTTCCCGGCCTACCTGCAGCAGCTGACCATGGAAT
CCAACGGCAAGTCCGTGCGTTGGGACGGCACCCCCGTCACCTCCGAGACCGGCGAGATCTTCTGGGGCGAGCCTGGCACC
AACGGCCAGCACGCCTTCTACCAGCTGATCCACCAGGGCACCCAGCTCATCCCGGCCGACTTCATCGCGTTCGTCAACAC
CCCGAACCCGACCAAGGACGGCGACCAGGACGTGCACGAGCTGTTCCTGGGCAACTACTTCGCTCAGACCAAGGCCCTGG
CGTTCGGCAAGACCGCTGACGAAGTGCGCGCCGAGGGTACTCCGGAGGAGATCGTCCCGGCCCGCGTGTTCACCGGCAAC
CGTCCGACCACCTCCATCTTCGGCGTGGCCCTGACCCCGTTCGCAGTCGGCGAGCTCATCGCCCTGTACGAGCACATCAC
CTTCGTGGAAGGCACCGTGTGGGGCCTCGACTCCTACGATCAGTGGGGCGTCGAGCTCGGCAAGCAGCTTGCCAAGCAGA
TCACCCCGGCCATCTCCCAGGACGACGACGCCCTCGCCGCCCAGGACGCCTCCACCCAGAGCCTGATCAAGTTCTACCGC
GCCAACCGCGAGTTCTGA

Upstream 100 bases:

>100_bases
TGTTCATGTCCGAATTTGTGAGTATTCTGTTTGGTGATACGGAGCGCATCCGAGCCGTGAGCGAAGGCGCTCCAGTCACT
GATGAAAGGAATGGAATCCT

Downstream 100 bases:

>100_bases
TCTCCGCTCCTGCGTCGCTTCAATCAGAACTCGCGGTTGGCGCGCCGCGCTGTGTTGTTTGATGGTCGGTCTGGCGACCG
TCCATGGCGCGAGTTCTGAT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MAINPPVDATQTPEWAALQKHYDELQAEGVSLKKWFAEDAERVEKLSFDAGDLHFDLSKNLIKPETLQLFADLAKAVKLD
ERTKAMYTGVHINNTEDRAVLHTALRRPVEDEGKYIVDGQDTVKDVREVLDRIYAFADKVRSGEWTGVTGKKIETVVNIG
IGGSDLGPVMVYEALKPYADAGISARYISNIDPNDLAEKTKGLDPETTLFIIVSKTFTTLETLTNAREARTWLLEELKAK
GAIDGSDEKNAEAIKKHFVAVSTNLEKVAEFGIDPNNAFGFWNWVGGRYSVDSAVGTSLAVVFGPARFEEFLHGFHEIDE
YFANTPFEKNVVVLLGMLNVWYRNFFKVASHAVLPYDQYLHRFPAYLQQLTMESNGKSVRWDGTPVTSETGEIFWGEPGT
NGQHAFYQLIHQGTQLIPADFIAFVNTPNPTKDGDQDVHELFLGNYFAQTKALAFGKTADEVRAEGTPEEIVPARVFTGN
RPTTSIFGVALTPFAVGELIALYEHITFVEGTVWGLDSYDQWGVELGKQLAKQITPAISQDDDALAAQDASTQSLIKFYR
ANREF

Sequences:

>Translated_565_residues
MAINPPVDATQTPEWAALQKHYDELQAEGVSLKKWFAEDAERVEKLSFDAGDLHFDLSKNLIKPETLQLFADLAKAVKLD
ERTKAMYTGVHINNTEDRAVLHTALRRPVEDEGKYIVDGQDTVKDVREVLDRIYAFADKVRSGEWTGVTGKKIETVVNIG
IGGSDLGPVMVYEALKPYADAGISARYISNIDPNDLAEKTKGLDPETTLFIIVSKTFTTLETLTNAREARTWLLEELKAK
GAIDGSDEKNAEAIKKHFVAVSTNLEKVAEFGIDPNNAFGFWNWVGGRYSVDSAVGTSLAVVFGPARFEEFLHGFHEIDE
YFANTPFEKNVVVLLGMLNVWYRNFFKVASHAVLPYDQYLHRFPAYLQQLTMESNGKSVRWDGTPVTSETGEIFWGEPGT
NGQHAFYQLIHQGTQLIPADFIAFVNTPNPTKDGDQDVHELFLGNYFAQTKALAFGKTADEVRAEGTPEEIVPARVFTGN
RPTTSIFGVALTPFAVGELIALYEHITFVEGTVWGLDSYDQWGVELGKQLAKQITPAISQDDDALAAQDASTQSLIKFYR
ANREF
>Mature_564_residues
AINPPVDATQTPEWAALQKHYDELQAEGVSLKKWFAEDAERVEKLSFDAGDLHFDLSKNLIKPETLQLFADLAKAVKLDE
RTKAMYTGVHINNTEDRAVLHTALRRPVEDEGKYIVDGQDTVKDVREVLDRIYAFADKVRSGEWTGVTGKKIETVVNIGI
GGSDLGPVMVYEALKPYADAGISARYISNIDPNDLAEKTKGLDPETTLFIIVSKTFTTLETLTNAREARTWLLEELKAKG
AIDGSDEKNAEAIKKHFVAVSTNLEKVAEFGIDPNNAFGFWNWVGGRYSVDSAVGTSLAVVFGPARFEEFLHGFHEIDEY
FANTPFEKNVVVLLGMLNVWYRNFFKVASHAVLPYDQYLHRFPAYLQQLTMESNGKSVRWDGTPVTSETGEIFWGEPGTN
GQHAFYQLIHQGTQLIPADFIAFVNTPNPTKDGDQDVHELFLGNYFAQTKALAFGKTADEVRAEGTPEEIVPARVFTGNR
PTTSIFGVALTPFAVGELIALYEHITFVEGTVWGLDSYDQWGVELGKQLAKQITPAISQDDDALAAQDASTQSLIKFYRA
NREF

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=568, Percent_Identity=49.1197183098592, Blast_Score=542, Evalue=1e-154,
Organism=Homo sapiens, GI296080693, Length=568, Percent_Identity=45.5985915492958, Blast_Score=486, Evalue=1e-137,
Organism=Escherichia coli, GI1790457, Length=566, Percent_Identity=50.3533568904594, Blast_Score=538, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI71996708, Length=569, Percent_Identity=50.9666080843585, Blast_Score=526, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI71996703, Length=569, Percent_Identity=50.9666080843585, Blast_Score=525, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6319673, Length=558, Percent_Identity=50.179211469534, Blast_Score=529, Evalue=1e-151,
Organism=Drosophila melanogaster, GI24651916, Length=571, Percent_Identity=51.3134851138354, Blast_Score=555, Evalue=1e-158,
Organism=Drosophila melanogaster, GI24651914, Length=571, Percent_Identity=51.3134851138354, Blast_Score=555, Evalue=1e-158,
Organism=Drosophila melanogaster, GI17737445, Length=571, Percent_Identity=51.3134851138354, Blast_Score=555, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 62883; Mature: 62752

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAINPPVDATQTPEWAALQKHYDELQAEGVSLKKWFAEDAERVEKLSFDAGDLHFDLSKN
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
LIKPETLQLFADLAKAVKLDERTKAMYTGVHINNTEDRAVLHTALRRPVEDEGKYIVDGQ
CCCHHHHHHHHHHHHHHHHHHHHHHHEECEEECCCCHHHHHHHHHHCCCCCCCCEEECCH
DTVKDVREVLDRIYAFADKVRSGEWTGVTGKKIETVVNIGIGGSDLGPVMVYEALKPYAD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
AGISARYISNIDPNDLAEKTKGLDPETTLFIIVSKTFTTLETLTNAREARTWLLEELKAK
CCCCCHHCCCCCHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
GAIDGSDEKNAEAIKKHFVAVSTNLEKVAEFGIDPNNAFGFWNWVGGRYSVDSAVGTSLA
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEECCCCCEECCHHHCCEEE
VVFGPARFEEFLHGFHEIDEYFANTPFEKNVVVLLGMLNVWYRNFFKVASHAVLPYDQYL
EEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
HRFPAYLQQLTMESNGKSVRWDGTPVTSETGEIFWGEPGTNGQHAFYQLIHQGTQLIPAD
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHH
FIAFVNTPNPTKDGDQDVHELFLGNYFAQTKALAFGKTADEVRAEGTPEEIVPARVFTGN
HHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHCCCCEECCC
RPTTSIFGVALTPFAVGELIALYEHITFVEGTVWGLDSYDQWGVELGKQLAKQITPAISQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHCCCCCC
DDDALAAQDASTQSLIKFYRANREF
CCCHHHHCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AINPPVDATQTPEWAALQKHYDELQAEGVSLKKWFAEDAERVEKLSFDAGDLHFDLSKN
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
LIKPETLQLFADLAKAVKLDERTKAMYTGVHINNTEDRAVLHTALRRPVEDEGKYIVDGQ
CCCHHHHHHHHHHHHHHHHHHHHHHHEECEEECCCCHHHHHHHHHHCCCCCCCCEEECCH
DTVKDVREVLDRIYAFADKVRSGEWTGVTGKKIETVVNIGIGGSDLGPVMVYEALKPYAD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
AGISARYISNIDPNDLAEKTKGLDPETTLFIIVSKTFTTLETLTNAREARTWLLEELKAK
CCCCCHHCCCCCHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHC
GAIDGSDEKNAEAIKKHFVAVSTNLEKVAEFGIDPNNAFGFWNWVGGRYSVDSAVGTSLA
CCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCEEEECCCCCEECCHHHCCEEE
VVFGPARFEEFLHGFHEIDEYFANTPFEKNVVVLLGMLNVWYRNFFKVASHAVLPYDQYL
EEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
HRFPAYLQQLTMESNGKSVRWDGTPVTSETGEIFWGEPGTNGQHAFYQLIHQGTQLIPAD
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCHH
FIAFVNTPNPTKDGDQDVHELFLGNYFAQTKALAFGKTADEVRAEGTPEEIVPARVFTGN
HHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHCCCCEECCC
RPTTSIFGVALTPFAVGELIALYEHITFVEGTVWGLDSYDQWGVELGKQLAKQITPAISQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHCCCCCC
DDDALAAQDASTQSLIKFYRANREF
CCCHHHHCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]