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The map label for this gene is fkpA [C]

Identifier: 213691229

GI number: 213691229

Start: 362507

End: 363496

Strand: Reverse

Name: fkpA [C]

Synonym: Blon_0312

Alternate gene names: 213691229

Gene position: 363496-362507 (Counterclockwise)

Preceding gene: 213691233

Following gene: 213691218

Centisome position: 12.83

GC content: 56.67

Gene sequence:

>990_bases
ATGCGTAAGTCTGTTAAGTCTATGTTATCCCCCCTCGGCAAGGCCGTTGCTCTTGCCTGTTCACTGGCGATGTGCGTGTC
GCTGGCTGCCTGCTCCAGTTCGAGCTCGGACTCGAAATCCTCTTCTTCCGATTCCTCTTCATCTTCCGACTCTTCTGACA
AGAAGGGCCAAATTGCCGGCGTGACCGCCAAGGGCAAGCTCGGCGAGAAGCCGACCATCTCCTTTAATACGCCGATGACC
GTGTCCGACGGCTCCTATGTGGTGCTGCAAAAGGGCGATGGCGACGTGATCGAGGAGGGCGACCGCGTCTGTGCCCAAGG
CATCGCGCTCAACGTTAAAGACGGCACCGAGCTCATGGACACCTGGACCAAGAACACGCCGGATTGCTCGCTGAAGGTGG
ATTCCAAGACCCTCTCCTCGACCTACTACAACCAGATCAAGGGCGCCAAGATCAACACCACGATCGGCTTTGGCGTCAAC
GCTCAGGATTCGTCCGGATACTCTTACATTCTGGCGATGACGTTTGTCTCCAAGTCCAAGGACCTGAAGAAGGCCACTGG
CGAGGAAGTCAAGAATGTGCCGGCCAATCTGCCGAAGGTGACGCGAGCCAAGAATGGCAAGCCGTCCATTGACATGAACG
GTCAGGGTTCGGTTGATTCGCTGATCTCGCAGACGCTGATCAAGGGTAACGGCGCCAAGCTGACCGACAAGAACACCGTG
GTGGTCAAGTACACCGGTTGGCTTACGAATGGCAAGCAGTTCGATTCGTCCTGGGATCGCGATTCCACAATCGACGCCGA
TCTGTTCAGCGATTCCAGCGGCCAGCATCAGGTTATCGAGGGCTGGCAGAAGGGTCTGGTCGGCCAGACCGTCGGCTCTC
AGGTTCTGCTGGTGATTCCGCCGGATCAGGCCTATGGAGATAAGGAGCAAGGTTCGATTCCCGCCAACTCCACGTTGGTC
TTCGTAATCGATATTCTCGCCGCGTACTAA

Upstream 100 bases:

>100_bases
GTCTGTTCTTCAGCACTCATAACTCAACCATTCTACAATCTTCACCTGTTTATTACCTAGGAGCGCAGAAAATCAAGGTT
TACCAGTAGGGTGGTGTGCC

Downstream 100 bases:

>100_bases
AAGATAAAGATATAGCAGGGGCTCCCTCTGATGAGGGAGCCCCTGCTATATCTAGAACAGCCTGAGACTGTCGTCCTCGG
TGCCTTTCATATCGTCGTAA

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MRKSVKSMLSPLGKAVALACSLAMCVSLAACSSSSSDSKSSSSDSSSSSDSSDKKGQIAGVTAKGKLGEKPTISFNTPMT
VSDGSYVVLQKGDGDVIEEGDRVCAQGIALNVKDGTELMDTWTKNTPDCSLKVDSKTLSSTYYNQIKGAKINTTIGFGVN
AQDSSGYSYILAMTFVSKSKDLKKATGEEVKNVPANLPKVTRAKNGKPSIDMNGQGSVDSLISQTLIKGNGAKLTDKNTV
VVKYTGWLTNGKQFDSSWDRDSTIDADLFSDSSGQHQVIEGWQKGLVGQTVGSQVLLVIPPDQAYGDKEQGSIPANSTLV
FVIDILAAY

Sequences:

>Translated_329_residues
MRKSVKSMLSPLGKAVALACSLAMCVSLAACSSSSSDSKSSSSDSSSSSDSSDKKGQIAGVTAKGKLGEKPTISFNTPMT
VSDGSYVVLQKGDGDVIEEGDRVCAQGIALNVKDGTELMDTWTKNTPDCSLKVDSKTLSSTYYNQIKGAKINTTIGFGVN
AQDSSGYSYILAMTFVSKSKDLKKATGEEVKNVPANLPKVTRAKNGKPSIDMNGQGSVDSLISQTLIKGNGAKLTDKNTV
VVKYTGWLTNGKQFDSSWDRDSTIDADLFSDSSGQHQVIEGWQKGLVGQTVGSQVLLVIPPDQAYGDKEQGSIPANSTLV
FVIDILAAY
>Mature_329_residues
MRKSVKSMLSPLGKAVALACSLAMCVSLAACSSSSSDSKSSSSDSSSSSDSSDKKGQIAGVTAKGKLGEKPTISFNTPMT
VSDGSYVVLQKGDGDVIEEGDRVCAQGIALNVKDGTELMDTWTKNTPDCSLKVDSKTLSSTYYNQIKGAKINTTIGFGVN
AQDSSGYSYILAMTFVSKSKDLKKATGEEVKNVPANLPKVTRAKNGKPSIDMNGQGSVDSLISQTLIKGNGAKLTDKNTV
VVKYTGWLTNGKQFDSSWDRDSTIDADLFSDSSGQHQVIEGWQKGLVGQTVGSQVLLVIPPDQAYGDKEQGSIPANSTLV
FVIDILAAY

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=105, Percent_Identity=40, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4503725, Length=105, Percent_Identity=40, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI4758380, Length=105, Percent_Identity=39.0476190476191, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789745, Length=106, Percent_Identity=40.5660377358491, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324194, Length=100, Percent_Identity=42, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363946, Length=91, Percent_Identity=40.6593406593407, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17352457, Length=91, Percent_Identity=40.6593406593407, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24655568, Length=98, Percent_Identity=40.8163265306122, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 34646; Mature: 34646

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSVKSMLSPLGKAVALACSLAMCVSLAACSSSSSDSKSSSSDSSSSSDSSDKKGQIAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
VTAKGKLGEKPTISFNTPMTVSDGSYVVLQKGDGDVIEEGDRVCAQGIALNVKDGTELMD
EEECCCCCCCCEEECCCCEEECCCCEEEEECCCCCHHHHCCHHHHCCEEEEECCCHHHHH
TWTKNTPDCSLKVDSKTLSSTYYNQIKGAKINTTIGFGVNAQDSSGYSYILAMTFVSKSK
HHCCCCCCCEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEEEHHHCCH
DLKKATGEEVKNVPANLPKVTRAKNGKPSIDMNGQGSVDSLISQTLIKGNGAKLTDKNTV
HHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCEE
VVKYTGWLTNGKQFDSSWDRDSTIDADLFSDSSGQHQVIEGWQKGLVGQTVGSQVLLVIP
EEEEECEECCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEC
PDQAYGDKEQGSIPANSTLVFVIDILAAY
CCCCCCCCCCCCCCCCCEEEEEEHHHHCC
>Mature Secondary Structure
MRKSVKSMLSPLGKAVALACSLAMCVSLAACSSSSSDSKSSSSDSSSSSDSSDKKGQIAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
VTAKGKLGEKPTISFNTPMTVSDGSYVVLQKGDGDVIEEGDRVCAQGIALNVKDGTELMD
EEECCCCCCCCEEECCCCEEECCCCEEEEECCCCCHHHHCCHHHHCCEEEEECCCHHHHH
TWTKNTPDCSLKVDSKTLSSTYYNQIKGAKINTTIGFGVNAQDSSGYSYILAMTFVSKSK
HHCCCCCCCEEEECCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCEEEEEEEHHHCCH
DLKKATGEEVKNVPANLPKVTRAKNGKPSIDMNGQGSVDSLISQTLIKGNGAKLTDKNTV
HHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEECCCCEE
VVKYTGWLTNGKQFDSSWDRDSTIDADLFSDSSGQHQVIEGWQKGLVGQTVGSQVLLVIP
EEEEECEECCCCCCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEC
PDQAYGDKEQGSIPANSTLVFVIDILAAY
CCCCCCCCCCCCCCCCCEEEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7522844; 12948626 [H]