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The map label for this gene is atpA [H]

Identifier: 213691224

GI number: 213691224

Start: 357265

End: 358896

Strand: Direct

Name: atpA [H]

Synonym: Blon_0307

Alternate gene names: 213691224

Gene position: 357265-358896 (Clockwise)

Preceding gene: 213691223

Following gene: 213691225

Centisome position: 12.61

GC content: 63.11

Gene sequence:

>1632_bases
ATGGCAGAACTGACCATCGATCCCGCCTCGATTCGCAAGGCCCTCGACGACTTCGTGTCGTCGTACAAGCCGAGCGACAC
CCCCACCCAAGAGGTGGGATATGTCGCCACGGCCGGTGACGGCATTGCGCACGTGACGGGATTGCCTGGTTGCATGGCCA
ATGAGCTGCTGACGTTCGAAGACGGCACGCTCGGCCTGGCGTTCAACCTTGACGCCCGTGAGATCGGCGTGGTGATCCTC
GGCGATTTCGCTGGAATCGAGGAAGGCCAGGAAGTGCGCCGCACCGGCGAAGTGCTCTCCGTGCCCGTCGGCGACGGCTA
CCTCGGTCGCGTCGTGGACCCGCTGGGCAAGCCGATCGACGGCCTCGGTGAGATTCAGAACATCGAAGGCCGGCGTATCC
TCGAAGCCCAGGCCCCCGACGTGATGCACCGCCACCCGGTCGACGAGCCGCTGTCCACCGGCCTCAAGGCCATCGACGCG
ATGACCCCGATCGGCCGCGGCCAGCGCCAGCTCATCATCGGCGACCGCCAGACCGGTAAGACCGCCATTGCGATCGATAC
CATCATCAACCAGAAGGCCAACTGGGAATCCGGCGACCCGAAGAAGCAGGTCCGCTGCATCTACGTGGCCATCGGCCAGA
AGGGCTCCACCATCGCCTCGGTGAAGCAGAGCCTGGAAGACGCCGGCGCCATGGAGTACACCACCATCGTGGCCTCCCCG
GCAGCCGATTCCGCTGGCTTCAAGTACATCGCCCCGTACACCGGCTCGGCCATCGGCCAGCACTGGATGTACAACGGCAA
GCATGTGCTCATCGTCTTCGATGACTTGTCCAAGCAGGCAGAGGCCTATCGTTCGATTTCCCTGCTGCTGCGCCGCCCGC
CGGGGCGTGAGGCATACCCGGGTGATGTGTTCTACCTGCACTCCCGCCTGCTCGAACGTTGCGCCAAGGTCTCCGATGAC
CTGGGCGGCGGTTCGATGACGGGTCTGCCGATCGTCGAGACCAAGGCGAACGATGTGTCCGCCTATATCCCGACCAACGT
GATCTCCATCACCGACGGCCAGATCTTCCTGCAGTCCGATCTGTTCAACGCCAACCAGCGCCCCGCCGTGGACGTCGGTA
TCTCCGTCTCCCGAGTCGGTGGCGCCGCACAGACCAAGGCTCTGAAGAAGGTCTCCGGTACGCTGAAGATCTCCCTGGCA
CAGTACCGTTCGCTGGAATCCTTCGCCATGTTCGCCTCCGATCTGGATGCGGCATCCAAGGCCCAGCTGACCCGTGGTGC
CCACTTGACCGAGCTGTTGAAGCAGCCGCAGTTCCACCCGTACTCGCCGGAACAGGAAGTCGTGTCCGTATGGACCGGCA
CCCACGGCAAGCTCGACGACCTCGACCTGAAGGACGTCCTTCCGTTCGAGCAGGGACTGCTGGACTACATCGACCACAAC
ACCGATATCCTCAAGACCATTCGCGAGACCGAGGAATTCACCGCCGACACCGAGGCTGCCCTCGATAAGGCCGTGGATGA
GTTCCGCTCGACGTTCGTCTCCGGCAGCGGCAAGCCGTTGGAAGAGAAGAAGGTCGAAAGCGTCAAGGCCGCGCCGGTCG
ATCAGGAAAAGATCGTGGCGGGAGAAAAGTAA

Upstream 100 bases:

>100_bases
GCAGACGGAGGCGACTCCGGCCTGACCGGCCGAGCCAATCCGTCCAACACCACACACAAGCAAAGACTTGACTGAACAAT
AACCAATAGAAGGAGTGATC

Downstream 100 bases:

>100_bases
GCCATGGGCTCGCAACTCGCATTGAAATCACGCATCCACTCCACCGAGTCGTTGGCGAAGATCTTCAACGCTCAGGAGAT
GATCGCGTCTTCGCATATCG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MAELTIDPASIRKALDDFVSSYKPSDTPTQEVGYVATAGDGIAHVTGLPGCMANELLTFEDGTLGLAFNLDAREIGVVIL
GDFAGIEEGQEVRRTGEVLSVPVGDGYLGRVVDPLGKPIDGLGEIQNIEGRRILEAQAPDVMHRHPVDEPLSTGLKAIDA
MTPIGRGQRQLIIGDRQTGKTAIAIDTIINQKANWESGDPKKQVRCIYVAIGQKGSTIASVKQSLEDAGAMEYTTIVASP
AADSAGFKYIAPYTGSAIGQHWMYNGKHVLIVFDDLSKQAEAYRSISLLLRRPPGREAYPGDVFYLHSRLLERCAKVSDD
LGGGSMTGLPIVETKANDVSAYIPTNVISITDGQIFLQSDLFNANQRPAVDVGISVSRVGGAAQTKALKKVSGTLKISLA
QYRSLESFAMFASDLDAASKAQLTRGAHLTELLKQPQFHPYSPEQEVVSVWTGTHGKLDDLDLKDVLPFEQGLLDYIDHN
TDILKTIRETEEFTADTEAALDKAVDEFRSTFVSGSGKPLEEKKVESVKAAPVDQEKIVAGEK

Sequences:

>Translated_543_residues
MAELTIDPASIRKALDDFVSSYKPSDTPTQEVGYVATAGDGIAHVTGLPGCMANELLTFEDGTLGLAFNLDAREIGVVIL
GDFAGIEEGQEVRRTGEVLSVPVGDGYLGRVVDPLGKPIDGLGEIQNIEGRRILEAQAPDVMHRHPVDEPLSTGLKAIDA
MTPIGRGQRQLIIGDRQTGKTAIAIDTIINQKANWESGDPKKQVRCIYVAIGQKGSTIASVKQSLEDAGAMEYTTIVASP
AADSAGFKYIAPYTGSAIGQHWMYNGKHVLIVFDDLSKQAEAYRSISLLLRRPPGREAYPGDVFYLHSRLLERCAKVSDD
LGGGSMTGLPIVETKANDVSAYIPTNVISITDGQIFLQSDLFNANQRPAVDVGISVSRVGGAAQTKALKKVSGTLKISLA
QYRSLESFAMFASDLDAASKAQLTRGAHLTELLKQPQFHPYSPEQEVVSVWTGTHGKLDDLDLKDVLPFEQGLLDYIDHN
TDILKTIRETEEFTADTEAALDKAVDEFRSTFVSGSGKPLEEKKVESVKAAPVDQEKIVAGEK
>Mature_542_residues
AELTIDPASIRKALDDFVSSYKPSDTPTQEVGYVATAGDGIAHVTGLPGCMANELLTFEDGTLGLAFNLDAREIGVVILG
DFAGIEEGQEVRRTGEVLSVPVGDGYLGRVVDPLGKPIDGLGEIQNIEGRRILEAQAPDVMHRHPVDEPLSTGLKAIDAM
TPIGRGQRQLIIGDRQTGKTAIAIDTIINQKANWESGDPKKQVRCIYVAIGQKGSTIASVKQSLEDAGAMEYTTIVASPA
ADSAGFKYIAPYTGSAIGQHWMYNGKHVLIVFDDLSKQAEAYRSISLLLRRPPGREAYPGDVFYLHSRLLERCAKVSDDL
GGGSMTGLPIVETKANDVSAYIPTNVISITDGQIFLQSDLFNANQRPAVDVGISVSRVGGAAQTKALKKVSGTLKISLAQ
YRSLESFAMFASDLDAASKAQLTRGAHLTELLKQPQFHPYSPEQEVVSVWTGTHGKLDDLDLKDVLPFEQGLLDYIDHNT
DILKTIRETEEFTADTEAALDKAVDEFRSTFVSGSGKPLEEKKVESVKAAPVDQEKIVAGEK

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=484, Percent_Identity=54.3388429752066, Blast_Score=535, Evalue=1e-152,
Organism=Homo sapiens, GI4757810, Length=484, Percent_Identity=54.3388429752066, Blast_Score=535, Evalue=1e-152,
Organism=Homo sapiens, GI19913428, Length=335, Percent_Identity=28.3582089552239, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI19913426, Length=296, Percent_Identity=29.3918918918919, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI32189394, Length=407, Percent_Identity=25.0614250614251, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1790172, Length=491, Percent_Identity=50.9164969450102, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI1788251, Length=344, Percent_Identity=28.4883720930233, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790170, Length=405, Percent_Identity=25.1851851851852, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=484, Percent_Identity=57.0247933884297, Blast_Score=563, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988080, Length=484, Percent_Identity=57.0247933884297, Blast_Score=562, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71988074, Length=484, Percent_Identity=52.8925619834711, Blast_Score=509, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17510931, Length=292, Percent_Identity=30.4794520547945, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17570191, Length=293, Percent_Identity=31.0580204778157, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=406, Percent_Identity=23.8916256157635, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=485, Percent_Identity=54.8453608247423, Blast_Score=538, Evalue=1e-154,
Organism=Saccharomyces cerevisiae, GI6319603, Length=341, Percent_Identity=29.3255131964809, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6322581, Length=421, Percent_Identity=25.1781472684086, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24658560, Length=484, Percent_Identity=54.9586776859504, Blast_Score=532, Evalue=1e-151,
Organism=Drosophila melanogaster, GI281361666, Length=303, Percent_Identity=29.3729372937294, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646341, Length=303, Percent_Identity=29.3729372937294, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136796, Length=303, Percent_Identity=29.3729372937294, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28574560, Length=390, Percent_Identity=26.4102564102564, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24638766, Length=398, Percent_Identity=24.1206030150754, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 58529; Mature: 58398

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELTIDPASIRKALDDFVSSYKPSDTPTQEVGYVATAGDGIAHVTGLPGCMANELLTFE
CCEEECCHHHHHHHHHHHHHHCCCCCCCHHHCCEEEECCCCEEECCCCCCHHHCCEEEEC
DGTLGLAFNLDAREIGVVILGDFAGIEEGQEVRRTGEVLSVPVGDGYLGRVVDPLGKPID
CCCEEEEEECCHHHEEEEEEECCCCCCCCHHHHHCCCEEEEECCCCHHHHHHHHCCCCCC
GLGEIQNIEGRRILEAQAPDVMHRHPVDEPLSTGLKAIDAMTPIGRGQRQLIIGDRQTGK
CCHHHCCCCCCEEEECCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
TAIAIDTIINQKANWESGDPKKQVRCIYVAIGQKGSTIASVKQSLEDAGAMEYTTIVASP
EEEEEEHHHCCCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEECC
AADSAGFKYIAPYTGSAIGQHWMYNGKHVLIVFDDLSKQAEAYRSISLLLRRPPGREAYP
CCCCCCCEEECCCCCCHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC
GDVFYLHSRLLERCAKVSDDLGGGSMTGLPIVETKANDVSAYIPTNVISITDGQIFLQSD
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCEEEEEEC
LFNANQRPAVDVGISVSRVGGAAQTKALKKVSGTLKISLAQYRSLESFAMFASDLDAASK
CCCCCCCCCEEECCCHHHCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCHHHH
AQLTRGAHLTELLKQPQFHPYSPEQEVVSVWTGTHGKLDDLDLKDVLPFEQGLLDYIDHN
HHHHCCHHHHHHHHCCCCCCCCCHHHHHEEECCCCCCCCCCCHHHCCCHHHHHHHHHCCC
TDILKTIRETEEFTADTEAALDKAVDEFRSTFVSGSGKPLEEKKVESVKAAPVDQEKIVA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHCC
GEK
CCC
>Mature Secondary Structure 
AELTIDPASIRKALDDFVSSYKPSDTPTQEVGYVATAGDGIAHVTGLPGCMANELLTFE
CEEECCHHHHHHHHHHHHHHCCCCCCCHHHCCEEEECCCCEEECCCCCCHHHCCEEEEC
DGTLGLAFNLDAREIGVVILGDFAGIEEGQEVRRTGEVLSVPVGDGYLGRVVDPLGKPID
CCCEEEEEECCHHHEEEEEEECCCCCCCCHHHHHCCCEEEEECCCCHHHHHHHHCCCCCC
GLGEIQNIEGRRILEAQAPDVMHRHPVDEPLSTGLKAIDAMTPIGRGQRQLIIGDRQTGK
CCHHHCCCCCCEEEECCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCC
TAIAIDTIINQKANWESGDPKKQVRCIYVAIGQKGSTIASVKQSLEDAGAMEYTTIVASP
EEEEEEHHHCCCCCCCCCCCHHHEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEECC
AADSAGFKYIAPYTGSAIGQHWMYNGKHVLIVFDDLSKQAEAYRSISLLLRRPPGREAYP
CCCCCCCEEECCCCCCHHHHHHEECCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC
GDVFYLHSRLLERCAKVSDDLGGGSMTGLPIVETKANDVSAYIPTNVISITDGQIFLQSD
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCEEEEECCEEEEEEC
LFNANQRPAVDVGISVSRVGGAAQTKALKKVSGTLKISLAQYRSLESFAMFASDLDAASK
CCCCCCCCCEEECCCHHHCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCHHHH
AQLTRGAHLTELLKQPQFHPYSPEQEVVSVWTGTHGKLDDLDLKDVLPFEQGLLDYIDHN
HHHHCCHHHHHHHHCCCCCCCCCHHHHHEEECCCCCCCCCCCHHHCCCHHHHHHHHHCCC
TDILKTIRETEEFTADTEAALDKAVDEFRSTFVSGSGKPLEEKKVESVKAAPVDQEKIVA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHCC
GEK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA