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The map label for this gene is metA [H]

Identifier: 213691219

GI number: 213691219

Start: 353280

End: 354314

Strand: Direct

Name: metA [H]

Synonym: Blon_0302

Alternate gene names: 213691219

Gene position: 353280-354314 (Clockwise)

Preceding gene: 213691216

Following gene: 213691220

Centisome position: 12.47

GC content: 58.26

Gene sequence:

>1035_bases
ATGCCTATCAAGATCCCCAGTGGCCTGCCGGCCAGAGATATCCTCGATTCGGAGCGCATCTTCGCTCTGGAGAAGCCCGA
GGCGGAGCGTCAGCGCGTCCGTCCTCTCAAACTGGTGATCCTGAACTTGATGCCCAAGAAGATCGAAACCGAAACGCAGC
TGCTGAGACTGATCTCCAAATCGCCGCTGCAGGTCGAGATCGACTTCATGAAGACCTCCACACATGAGGCCACGCACGTT
TCCGCCGATCATCTCGTCAAGTTCTACGAAAACCTCGATGCGCTCAAAGACAACTATTACGACGGTTTTGTGGTCACCGG
CGCGCCTGTAGAGCATATGCCGTTCGAAGATGTGGACTACTGGGACGAGTTCAAGACGATTCTCGACTGGGCCTCCACCC
ATGTGTTCTCCACCATGTACCTGTGCTGGGGCGCGATGGGCGCACTGTACTACCGCTACGGCATCCACAAGGTGGATTAC
CCCGAGAAGATTTTCGGCGTATTCCCGCAGTACCTGCAGGACGAATACTGCTTCCTGACCAATGGTTTCGACGAGATTGA
TCTGCAGCCGCACTCCCGCCTCGCCGGCGTGAACGAAAACGAGGTACGTGCCAACCATGACCTTCAGATCTTGACTTGGG
GGCCACAGTCCGGCCCGGGCCTGATCGCCACACGTGACTTCTCCGAAGTGTTCGCGCTCGGCCATTGGGAGTACGGCAAG
TACACGCTCGCCGAGGAATACGAGCGCGATATGGCCAAGGGCATGACCAACGTGCCCTTCCCGAAGAACTACTTCCCGCA
TGACGATTCGAAACTGGAACCGTTGTTCGCCTGGCGCGCCCACGCCAATCTGCTGTGGCGCAACTGGCTCAACTGGGTGT
ACCAGACCACGCCGTATGACCTGACCGAGGTGCCGCAGCTCAGGGCTGAGAAGAAGCTCGGTACTGATCGTTCGATTCGG
CATGAGCCGGGCGGGCCGCGCCAGGATGATTTCGAGCCGTTCGCCCACGACGGATACGGAGTGATCAGAGGGTAG

Upstream 100 bases:

>100_bases
GCTACCGAGCTGCTCCACCCCGTGTCGCGCCGGTGTCCCGTGAACCGCCCGCCGGACGGATGCCTTGAACCGTTATCCCG
AACGTTGACATAATGGGAGC

Downstream 100 bases:

>100_bases
CGCAAATGCCGCACATCCTCGTATTGTGACTAATAGCGCACAATGCTTGCGCAACATCCGAAAAACCTTGCGCCGCCGCC
GATTCCAGAAGACGCGCCGG

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MPIKIPSGLPARDILDSERIFALEKPEAERQRVRPLKLVILNLMPKKIETETQLLRLISKSPLQVEIDFMKTSTHEATHV
SADHLVKFYENLDALKDNYYDGFVVTGAPVEHMPFEDVDYWDEFKTILDWASTHVFSTMYLCWGAMGALYYRYGIHKVDY
PEKIFGVFPQYLQDEYCFLTNGFDEIDLQPHSRLAGVNENEVRANHDLQILTWGPQSGPGLIATRDFSEVFALGHWEYGK
YTLAEEYERDMAKGMTNVPFPKNYFPHDDSKLEPLFAWRAHANLLWRNWLNWVYQTTPYDLTEVPQLRAEKKLGTDRSIR
HEPGGPRQDDFEPFAHDGYGVIRG

Sequences:

>Translated_344_residues
MPIKIPSGLPARDILDSERIFALEKPEAERQRVRPLKLVILNLMPKKIETETQLLRLISKSPLQVEIDFMKTSTHEATHV
SADHLVKFYENLDALKDNYYDGFVVTGAPVEHMPFEDVDYWDEFKTILDWASTHVFSTMYLCWGAMGALYYRYGIHKVDY
PEKIFGVFPQYLQDEYCFLTNGFDEIDLQPHSRLAGVNENEVRANHDLQILTWGPQSGPGLIATRDFSEVFALGHWEYGK
YTLAEEYERDMAKGMTNVPFPKNYFPHDDSKLEPLFAWRAHANLLWRNWLNWVYQTTPYDLTEVPQLRAEKKLGTDRSIR
HEPGGPRQDDFEPFAHDGYGVIRG
>Mature_343_residues
PIKIPSGLPARDILDSERIFALEKPEAERQRVRPLKLVILNLMPKKIETETQLLRLISKSPLQVEIDFMKTSTHEATHVS
ADHLVKFYENLDALKDNYYDGFVVTGAPVEHMPFEDVDYWDEFKTILDWASTHVFSTMYLCWGAMGALYYRYGIHKVDYP
EKIFGVFPQYLQDEYCFLTNGFDEIDLQPHSRLAGVNENEVRANHDLQILTWGPQSGPGLIATRDFSEVFALGHWEYGKY
TLAEEYERDMAKGMTNVPFPKNYFPHDDSKLEPLFAWRAHANLLWRNWLNWVYQTTPYDLTEVPQLRAEKKLGTDRSIRH
EPGGPRQDDFEPFAHDGYGVIRG

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=302, Percent_Identity=44.7019867549669, Blast_Score=268, Evalue=4e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 39998; Mature: 39866

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKIPSGLPARDILDSERIFALEKPEAERQRVRPLKLVILNLMPKKIETETQLLRLISK
CCCCCCCCCCHHHHCCCCCEEEECCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCC
SPLQVEIDFMKTSTHEATHVSADHLVKFYENLDALKDNYYDGFVVTGAPVEHMPFEDVDY
CCCEEEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHH
WDEFKTILDWASTHVFSTMYLCWGAMGALYYRYGIHKVDYPEKIFGVFPQYLQDEYCFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHCCCEEEEE
NGFDEIDLQPHSRLAGVNENEVRANHDLQILTWGPQSGPGLIATRDFSEVFALGHWEYGK
CCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCHHHHHHHCCCCCCC
YTLAEEYERDMAKGMTNVPFPKNYFPHDDSKLEPLFAWRAHANLLWRNWLNWVYQTTPYD
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
LTEVPQLRAEKKLGTDRSIRHEPGGPRQDDFEPFAHDGYGVIRG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCC
>Mature Secondary Structure 
PIKIPSGLPARDILDSERIFALEKPEAERQRVRPLKLVILNLMPKKIETETQLLRLISK
CCCCCCCCCHHHHCCCCCEEEECCCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCC
SPLQVEIDFMKTSTHEATHVSADHLVKFYENLDALKDNYYDGFVVTGAPVEHMPFEDVDY
CCCEEEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHH
WDEFKTILDWASTHVFSTMYLCWGAMGALYYRYGIHKVDYPEKIFGVFPQYLQDEYCFLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHCCCEEEEE
NGFDEIDLQPHSRLAGVNENEVRANHDLQILTWGPQSGPGLIATRDFSEVFALGHWEYGK
CCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCHHHHHHHCCCCCCC
YTLAEEYERDMAKGMTNVPFPKNYFPHDDSKLEPLFAWRAHANLLWRNWLNWVYQTTPYD
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
LTEVPQLRAEKKLGTDRSIRHEPGGPRQDDFEPFAHDGYGVIRG
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]