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The map label for this gene is bvgA [H]

Identifier: 213691136

GI number: 213691136

Start: 258878

End: 259546

Strand: Direct

Name: bvgA [H]

Synonym: Blon_0215

Alternate gene names: 213691136

Gene position: 258878-259546 (Clockwise)

Preceding gene: 213691135

Following gene: 213691137

Centisome position: 9.14

GC content: 65.62

Gene sequence:

>669_bases
ATGCCTTCATCCGAGCATGCCGACGGGCCGGCCGCCGTGGTGGTCCTCGACAACGACCCATTCGCGGCCCGCGCCCTTGC
GGCCGTCCTGTCCCACGATCCCCGTCATTTCCGTGTGATGTGGTGGTGCTCGTCCGCTCCTGAGGCCATCCAGCGTTGCC
TCCATGCCCGTGAGCTTCCCCAGGTGCTGGTCTGCGACATCGCACTGTCCGGGATGACGGGGATGGATGTCTGCGCCACG
ATCCGGAAGGCGGGGTCCCGCATCGGGGTCGTGTTGGTGACGGCCTACGACCCTAAAGAATACGTGGCGGACGCCGTTTC
CGTCGGAGCGCAGGCCGTGCTGGGCAAAGACGAGGCCATGCACGGTTTGATGGAGGCCGTTCAGAAGGCGGCCGCCGGTA
GGGGCGTGTGCGGATGCCCCGACGTGTCCGCCGCGGCGGGTCCAGGACGGAATGAAGGCGGTCCGAGGGTCGTTCCGCGT
CTGTCGGAAAGAGAGAGGGCCGTCATGAGGTTCTTCGCAAAGGGCATGAAGGCGGACGACATCGCGGAACGTCTGGACCT
GAGCCGCAACACCGTGATGACGTACAGCCACCGCGCGCTGCGCAAGCTGCATGCGGAGAATCGGGAGGAGGCGATGGAGA
AATGCGGCCGGTACGATCTGTTCAAGTGA

Upstream 100 bases:

>100_bases
GACGCCTGCGATCGGTGGCATGCCCGGACTGTCGCGTATGGACAGCCTCGAGACGCTGTCGTGATCCCGGCGCATCCCGC
GAATCGAGAGGAGATGTGGA

Downstream 100 bases:

>100_bases
GGCAGACGACTCGCTCCCTCCGGTCCGAACCCACGTCCGCAGGGAGTCGCGGAGGGACGATCGATCCCGTGCGCGTCGGC
CTGACGGCGCTGTACATGGT

Product: two component transcriptional regulator, LuxR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MPSSEHADGPAAVVVLDNDPFAARALAAVLSHDPRHFRVMWWCSSAPEAIQRCLHARELPQVLVCDIALSGMTGMDVCAT
IRKAGSRIGVVLVTAYDPKEYVADAVSVGAQAVLGKDEAMHGLMEAVQKAAAGRGVCGCPDVSAAAGPGRNEGGPRVVPR
LSERERAVMRFFAKGMKADDIAERLDLSRNTVMTYSHRALRKLHAENREEAMEKCGRYDLFK

Sequences:

>Translated_222_residues
MPSSEHADGPAAVVVLDNDPFAARALAAVLSHDPRHFRVMWWCSSAPEAIQRCLHARELPQVLVCDIALSGMTGMDVCAT
IRKAGSRIGVVLVTAYDPKEYVADAVSVGAQAVLGKDEAMHGLMEAVQKAAAGRGVCGCPDVSAAAGPGRNEGGPRVVPR
LSERERAVMRFFAKGMKADDIAERLDLSRNTVMTYSHRALRKLHAENREEAMEKCGRYDLFK
>Mature_221_residues
PSSEHADGPAAVVVLDNDPFAARALAAVLSHDPRHFRVMWWCSSAPEAIQRCLHARELPQVLVCDIALSGMTGMDVCATI
RKAGSRIGVVLVTAYDPKEYVADAVSVGAQAVLGKDEAMHGLMEAVQKAAAGRGVCGCPDVSAAAGPGRNEGGPRVVPRL
SERERAVMRFFAKGMKADDIAERLDLSRNTVMTYSHRALRKLHAENREEAMEKCGRYDLFK

Specific function: Member of the two-component regulatory system BvgS/BvgA. Activates the transcription of virulence genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788712, Length=191, Percent_Identity=26.7015706806283, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788521, Length=201, Percent_Identity=28.3582089552239, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788222, Length=193, Percent_Identity=24.3523316062176, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790102, Length=150, Percent_Identity=28.6666666666667, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24001; Mature: 23870

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSEHADGPAAVVVLDNDPFAARALAAVLSHDPRHFRVMWWCSSAPEAIQRCLHARELP
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCH
QVLVCDIALSGMTGMDVCATIRKAGSRIGVVLVTAYDPKEYVADAVSVGAQAVLGKDEAM
HHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHH
HGLMEAVQKAAAGRGVCGCPDVSAAAGPGRNEGGPRVVPRLSERERAVMRFFAKGMKADD
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
IAERLDLSRNTVMTYSHRALRKLHAENREEAMEKCGRYDLFK
HHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PSSEHADGPAAVVVLDNDPFAARALAAVLSHDPRHFRVMWWCSSAPEAIQRCLHARELP
CCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHCH
QVLVCDIALSGMTGMDVCATIRKAGSRIGVVLVTAYDPKEYVADAVSVGAQAVLGKDEAM
HHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCHHHH
HGLMEAVQKAAAGRGVCGCPDVSAAAGPGRNEGGPRVVPRLSERERAVMRFFAKGMKADD
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
IAERLDLSRNTVMTYSHRALRKLHAENREEAMEKCGRYDLFK
HHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]