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The map label for this gene is pgl [H]

Identifier: 213691129

GI number: 213691129

Start: 251846

End: 252688

Strand: Reverse

Name: pgl [H]

Synonym: Blon_0208

Alternate gene names: 213691129

Gene position: 252688-251846 (Counterclockwise)

Preceding gene: 213691130

Following gene: 213691126

Centisome position: 8.92

GC content: 60.38

Gene sequence:

>843_bases
ATGGCAACTCGAAAACTCATTGTGTATCCGAATAAAGATCTGATGATTCAGGCTGGCGCGCAACGTTTTGTCTTGGCGCT
ACTCGATTTGCTCGCCGAGCGACTGCCGGATGGCACGCACCGCACGCGCGTGGATGTGGCGCTGTCTGGCGGTTCGGCCG
CGCAGCCGTTGGGCTTGGTACTGAGCGATCCGCTGGCTGATGCGATTGATTGGTCGCGCGTGCATTTCTGGTGGAGCGAC
GAACGTTTTGTGCCGGCTTACGACACCGATCGCAATGCTTTGGAGGCCCGTCGCCTGCTGCTTGACCAGCTCGTGGCCAA
CGGCAAGCTGCCGGAATCAAATATCCATGAGATGGCGGCCGACGTTCGTTCCGCCGACGAGATCGCCGATGTTATGTCCG
ATGCCGACAGCGCCGACGATTCCGTTCGCGCCGCCGCCGATGCCGCGAATGATGCATTGCTGGACGCCGCCGCCCGCGAT
TATGGGGCCGAACTCATCCGTGAGCTTGGTCCGGAACCGGTAATCGATCTGATGATTCTCGGCATGGGACCGGACGGTCA
CTATGCGTCGCTGTTCCCTGGTCATGATGAGGTCAAGGTTACCGATAGGCTCACCGTGGGTGTGAACCACTCCCCCAAGA
TGCCGCCGCTGCGTGTTTCATTGACCGCGCCGCTCATCGCACGTTCACGCCATACGTGGTTCTTCGCCGCCGGTGCCGGC
AAAGCCGAATCGCTGGCCCATGTCTTCGAGCAGCCCAACAACCCGGATTACCCGTCCTCCTACGCCAACGGAGTGGACGA
GTTCACCTGGTTCTCCACCGAAGAAACCGTCACCGCATTGTGA

Upstream 100 bases:

>100_bases
AATGGCTGGATTCCCGGCATGCCACCCGTATTATGCGTTGTCAACTGACAACACAATCCACATTGCAAAGTACGACACAT
ACCCCATATAAGGACCATAC

Downstream 100 bases:

>100_bases
GTGAATTAAGCCCCCTCTGATGAGGGGGCTTAATTCGTCTATGGCTACGCCTCGATCTCAGGCTTGCTGTTTTCTCAGCT
CGGCTATCGCCGAGCCTGAA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MATRKLIVYPNKDLMIQAGAQRFVLALLDLLAERLPDGTHRTRVDVALSGGSAAQPLGLVLSDPLADAIDWSRVHFWWSD
ERFVPAYDTDRNALEARRLLLDQLVANGKLPESNIHEMAADVRSADEIADVMSDADSADDSVRAAADAANDALLDAAARD
YGAELIRELGPEPVIDLMILGMGPDGHYASLFPGHDEVKVTDRLTVGVNHSPKMPPLRVSLTAPLIARSRHTWFFAAGAG
KAESLAHVFEQPNNPDYPSSYANGVDEFTWFSTEETVTAL

Sequences:

>Translated_280_residues
MATRKLIVYPNKDLMIQAGAQRFVLALLDLLAERLPDGTHRTRVDVALSGGSAAQPLGLVLSDPLADAIDWSRVHFWWSD
ERFVPAYDTDRNALEARRLLLDQLVANGKLPESNIHEMAADVRSADEIADVMSDADSADDSVRAAADAANDALLDAAARD
YGAELIRELGPEPVIDLMILGMGPDGHYASLFPGHDEVKVTDRLTVGVNHSPKMPPLRVSLTAPLIARSRHTWFFAAGAG
KAESLAHVFEQPNNPDYPSSYANGVDEFTWFSTEETVTAL
>Mature_279_residues
ATRKLIVYPNKDLMIQAGAQRFVLALLDLLAERLPDGTHRTRVDVALSGGSAAQPLGLVLSDPLADAIDWSRVHFWWSDE
RFVPAYDTDRNALEARRLLLDQLVANGKLPESNIHEMAADVRSADEIADVMSDADSADDSVRAAADAANDALLDAAARDY
GAELIRELGPEPVIDLMILGMGPDGHYASLFPGHDEVKVTDRLTVGVNHSPKMPPLRVSLTAPLIARSRHTWFFAAGAGK
AESLAHVFEQPNNPDYPSSYANGVDEFTWFSTEETVTAL

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=264, Percent_Identity=28.7878787878788, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI52145310, Length=204, Percent_Identity=31.3725490196078, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115533060, Length=280, Percent_Identity=25.3571428571429, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115533058, Length=280, Percent_Identity=25.3571428571429, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321957, Length=242, Percent_Identity=28.5123966942149, Blast_Score=90, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321687, Length=238, Percent_Identity=28.9915966386555, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319918, Length=241, Percent_Identity=29.8755186721992, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324362, Length=236, Percent_Identity=28.3898305084746, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24641119, Length=248, Percent_Identity=31.4516129032258, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 30485; Mature: 30354

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRKLIVYPNKDLMIQAGAQRFVLALLDLLAERLPDGTHRTRVDVALSGGSAAQPLGLV
CCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHH
LSDPLADAIDWSRVHFWWSDERFVPAYDTDRNALEARRLLLDQLVANGKLPESNIHEMAA
HCCHHHHHCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DVRSADEIADVMSDADSADDSVRAAADAANDALLDAAARDYGAELIRELGPEPVIDLMIL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
GMGPDGHYASLFPGHDEVKVTDRLTVGVNHSPKMPPLRVSLTAPLIARSRHTWFFAAGAG
EECCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCEEEEECCHHHHCCCCCEEEEECCC
KAESLAHVFEQPNNPDYPSSYANGVDEFTWFSTEETVTAL
CHHHHHHHHHCCCCCCCCCHHHCCCHHHEEECCCCHHCCC
>Mature Secondary Structure 
ATRKLIVYPNKDLMIQAGAQRFVLALLDLLAERLPDGTHRTRVDVALSGGSAAQPLGLV
CCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHH
LSDPLADAIDWSRVHFWWSDERFVPAYDTDRNALEARRLLLDQLVANGKLPESNIHEMAA
HCCHHHHHCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
DVRSADEIADVMSDADSADDSVRAAADAANDALLDAAARDYGAELIRELGPEPVIDLMIL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEE
GMGPDGHYASLFPGHDEVKVTDRLTVGVNHSPKMPPLRVSLTAPLIARSRHTWFFAAGAG
EECCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCEEEEECCHHHHCCCCCEEEEECCC
KAESLAHVFEQPNNPDYPSSYANGVDEFTWFSTEETVTAL
CHHHHHHHHHCCCCCCCCCHHHCCCHHHEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]