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The map label for this gene is gltX [H]

Identifier: 213691112

GI number: 213691112

Start: 226745

End: 228265

Strand: Direct

Name: gltX [H]

Synonym: Blon_0191

Alternate gene names: 213691112

Gene position: 226745-228265 (Clockwise)

Preceding gene: 213691109

Following gene: 213691115

Centisome position: 8.0

GC content: 63.77

Gene sequence:

>1521_bases
ATGACTGATGCTGAAAACACCAAACCCGAACTGCCCAAGAACGTTCGTGTTCGCTTCTGCCCGTCGCCGACCGGTACCCC
GCACGTCGGCATGATTCGCACCGCCCTGTTCAACTGGGCGGAGGCCCGCGCCACCGGCGGCAAGCTGGTCTTCCGCATCG
AAGACACCGACGCCGTGCGCGACAGCGAGGAAAGCTATAACCAGATTCTCGAATCCCTGCGTTGGCTGGGTATCGACTGG
GACGAGGGCATCGATGTGGGTGGCCCTCACGGCCCGTACCGCCAGTCCGAGCGTACCGCCATCTACAAGGATGTTGCCGC
CAAGCTGCTCGAAGCCGGCTACGCCTACGAGTCCTTCTCCACCCCCGAGGAGATCAAGGAACGCAATCTCGCCGCGGGTC
GTCCGGCTGAGTTTGGCTACGACGGTTACGATCGCAACCTGACCGATGAGCAGAAGGAGGTTTTCCGTGCCGAAGGCCGC
AAGCCGGCGCTGCGTTTGCGCATGCCCGATGAGGATATCGCCTTCGACGATCTGATTCGTGGCACCATCGAGTTCAAGGC
CGGCTCCGTGCCGGACTATGTGATCGTGCGTCCGAACGGCGACCCGCTGTACACGCTGACCAATCCGGTCGATGACGCGA
TGATGGAAATCAACGTCGTGCTGCGTGGCGAGGACCTCCTGAGCTCCACCCCGCGCCAGATCGTGCTTTACCGTTACCTT
ATGGAACTTGGCATCGCCAAGGAGATGCCGCTGTTCGGCCACATGCCGTACGTGATGGGCCAGGGCAACAAGAAGCTCTC
CAAGCGCGACCCGGAGTCCAACCTGTTCAACCACCGCGACAACGGCTTCATCCGCGAGGGCCTGCTCAACTACCTGGCCC
TGCTCGGCTGGTCTATCGCCCCGGACCGCGACGTGTTCTCCATGGACGAGATGATCGAGAAGTTCGACGTGCGCGACGTC
AAGGCCAACCCGGCCCGCTTCGACATCGACAAGGCCATCTCCATCAACGCCGAGCACATCCGTATGCTCGAGCCCGAGGA
CTTCCTGCGCCGCTCGGTGCCGTACCTGCATCGTGACGGCGTGGTCGGTGCCGACGACTGGGATGCCCTGACCGACCGTG
AGCGTGAGGTGCTGACCGCCGCCGCTCCGCTGGTTCAGCCGCGTGTGCGTCTGCTGGGTGAGGTCGCCGGCATGGTCGGC
TCCCTGCTGTCCACCGAGGAATATCTGGAGCCTGCGGATGACGCCAAGAAGCAGCTCAAGGATTCCGCCGGCGAAGTGCT
GGACGCCGCCATCGCCGCCCTCGAGGGTGTGGATGAGGCCGATTGGAAGACCGACAACCTGCATGAGACCCTGAACAAGG
CTCTGGTTGAGGAGGGCGGCTACAAGCCGCGCCTCGCCTTCGGCCCGGTCCGTGTGGCCATGTCCGGCCGCCGCGTCTCC
CCGCCGCTGTTCGAGTCCATGGAGATCGTTGGCAAGCCGATCACCGTCGCCCGTCTCAAGGGCCTGCGGGCGCATCTGTG
A

Upstream 100 bases:

>100_bases
GAGGCATCACGCGGCGGGCTCATCGAATGACATGAATAACAAGGAATGCCTCCGCCGTCGCGGGCCGTCGCGTCCGGCGC
GCGCGGCACAATAGGGGACT

Downstream 100 bases:

>100_bases
TGCGTCGTCCACCGCACGCCGGCGGATGATGGGAGCGTGACGCATGGCGGGCATCCGTACATACGGATGCCCGCTTTCGC
GTTGCATGGGGTGTTCCCGC

Product: glutamyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamate--tRNA ligase; GluRS [H]

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MTDAENTKPELPKNVRVRFCPSPTGTPHVGMIRTALFNWAEARATGGKLVFRIEDTDAVRDSEESYNQILESLRWLGIDW
DEGIDVGGPHGPYRQSERTAIYKDVAAKLLEAGYAYESFSTPEEIKERNLAAGRPAEFGYDGYDRNLTDEQKEVFRAEGR
KPALRLRMPDEDIAFDDLIRGTIEFKAGSVPDYVIVRPNGDPLYTLTNPVDDAMMEINVVLRGEDLLSSTPRQIVLYRYL
MELGIAKEMPLFGHMPYVMGQGNKKLSKRDPESNLFNHRDNGFIREGLLNYLALLGWSIAPDRDVFSMDEMIEKFDVRDV
KANPARFDIDKAISINAEHIRMLEPEDFLRRSVPYLHRDGVVGADDWDALTDREREVLTAAAPLVQPRVRLLGEVAGMVG
SLLSTEEYLEPADDAKKQLKDSAGEVLDAAIAALEGVDEADWKTDNLHETLNKALVEEGGYKPRLAFGPVRVAMSGRRVS
PPLFESMEIVGKPITVARLKGLRAHL

Sequences:

>Translated_506_residues
MTDAENTKPELPKNVRVRFCPSPTGTPHVGMIRTALFNWAEARATGGKLVFRIEDTDAVRDSEESYNQILESLRWLGIDW
DEGIDVGGPHGPYRQSERTAIYKDVAAKLLEAGYAYESFSTPEEIKERNLAAGRPAEFGYDGYDRNLTDEQKEVFRAEGR
KPALRLRMPDEDIAFDDLIRGTIEFKAGSVPDYVIVRPNGDPLYTLTNPVDDAMMEINVVLRGEDLLSSTPRQIVLYRYL
MELGIAKEMPLFGHMPYVMGQGNKKLSKRDPESNLFNHRDNGFIREGLLNYLALLGWSIAPDRDVFSMDEMIEKFDVRDV
KANPARFDIDKAISINAEHIRMLEPEDFLRRSVPYLHRDGVVGADDWDALTDREREVLTAAAPLVQPRVRLLGEVAGMVG
SLLSTEEYLEPADDAKKQLKDSAGEVLDAAIAALEGVDEADWKTDNLHETLNKALVEEGGYKPRLAFGPVRVAMSGRRVS
PPLFESMEIVGKPITVARLKGLRAHL
>Mature_505_residues
TDAENTKPELPKNVRVRFCPSPTGTPHVGMIRTALFNWAEARATGGKLVFRIEDTDAVRDSEESYNQILESLRWLGIDWD
EGIDVGGPHGPYRQSERTAIYKDVAAKLLEAGYAYESFSTPEEIKERNLAAGRPAEFGYDGYDRNLTDEQKEVFRAEGRK
PALRLRMPDEDIAFDDLIRGTIEFKAGSVPDYVIVRPNGDPLYTLTNPVDDAMMEINVVLRGEDLLSSTPRQIVLYRYLM
ELGIAKEMPLFGHMPYVMGQGNKKLSKRDPESNLFNHRDNGFIREGLLNYLALLGWSIAPDRDVFSMDEMIEKFDVRDVK
ANPARFDIDKAISINAEHIRMLEPEDFLRRSVPYLHRDGVVGADDWDALTDREREVLTAAAPLVQPRVRLLGEVAGMVGS
LLSTEEYLEPADDAKKQLKDSAGEVLDAAIAALEGVDEADWKTDNLHETLNKALVEEGGYKPRLAFGPVRVAMSGRRVSP
PLFESMEIVGKPITVARLKGLRAHL

Specific function: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction:glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) [H]

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=487, Percent_Identity=31.6221765913758, Blast_Score=201, Evalue=1e-51,
Organism=Escherichia coli, GI1788743, Length=497, Percent_Identity=32.7967806841046, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI226510925, Length=298, Percent_Identity=28.5234899328859, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71993394, Length=312, Percent_Identity=35.8974358974359, Blast_Score=184, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6324540, Length=360, Percent_Identity=35, Blast_Score=191, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24665321, Length=497, Percent_Identity=31.3883299798793, Blast_Score=217, Evalue=2e-56,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR004527
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: =6.1.1.17 [H]

Molecular weight: Translated: 56763; Mature: 56632

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01094 UPF0076

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAENTKPELPKNVRVRFCPSPTGTPHVGMIRTALFNWAEARATGGKLVFRIEDTDAVR
CCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHC
DSEESYNQILESLRWLGIDWDEGIDVGGPHGPYRQSERTAIYKDVAAKLLEAGYAYESFS
CCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TPEEIKERNLAAGRPAEFGYDGYDRNLTDEQKEVFRAEGRKPALRLRMPDEDIAFDDLIR
CHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH
GTIEFKAGSVPDYVIVRPNGDPLYTLTNPVDDAMMEINVVLRGEDLLSSTPRQIVLYRYL
HHEEEECCCCCCEEEECCCCCEEEEECCCHHHHHEEEEEEEECCHHHHCCHHHHHHHHHH
MELGIAKEMPLFGHMPYVMGQGNKKLSKRDPESNLFNHRDNGFIREGLLNYLALLGWSIA
HHHCCHHCCCCCCCCCCEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PDRDVFSMDEMIEKFDVRDVKANPARFDIDKAISINAEHIRMLEPEDFLRRSVPYLHRDG
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCHHHEEECCHHHHHHHCCCCCCCCC
VVGADDWDALTDREREVLTAAAPLVQPRVRLLGEVAGMVGSLLSTEEYLEPADDAKKQLK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DSAGEVLDAAIAALEGVDEADWKTDNLHETLNKALVEEGGYKPRLAFGPVRVAMSGRRVS
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEECCCCCC
PPLFESMEIVGKPITVARLKGLRAHL
CHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TDAENTKPELPKNVRVRFCPSPTGTPHVGMIRTALFNWAEARATGGKLVFRIEDTDAVR
CCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHC
DSEESYNQILESLRWLGIDWDEGIDVGGPHGPYRQSERTAIYKDVAAKLLEAGYAYESFS
CCHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TPEEIKERNLAAGRPAEFGYDGYDRNLTDEQKEVFRAEGRKPALRLRMPDEDIAFDDLIR
CHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHH
GTIEFKAGSVPDYVIVRPNGDPLYTLTNPVDDAMMEINVVLRGEDLLSSTPRQIVLYRYL
HHEEEECCCCCCEEEECCCCCEEEEECCCHHHHHEEEEEEEECCHHHHCCHHHHHHHHHH
MELGIAKEMPLFGHMPYVMGQGNKKLSKRDPESNLFNHRDNGFIREGLLNYLALLGWSIA
HHHCCHHCCCCCCCCCCEECCCCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCC
PDRDVFSMDEMIEKFDVRDVKANPARFDIDKAISINAEHIRMLEPEDFLRRSVPYLHRDG
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCHHHEEECCHHHHHHHCCCCCCCCC
VVGADDWDALTDREREVLTAAAPLVQPRVRLLGEVAGMVGSLLSTEEYLEPADDAKKQLK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
DSAGEVLDAAIAALEGVDEADWKTDNLHETLNKALVEEGGYKPRLAFGPVRVAMSGRRVS
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEECCCCCC
PPLFESMEIVGKPITVARLKGLRAHL
CHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA