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The map label for this gene is ribH [H]

Identifier: 213159129

GI number: 213159129

Start: 3961820

End: 3962290

Strand: Direct

Name: ribH [H]

Synonym: AB57_3839

Alternate gene names: 213159129

Gene position: 3961820-3962290 (Clockwise)

Preceding gene: 213159128

Following gene: 213159130

Centisome position: 97.81

GC content: 41.83

Gene sequence:

>471_bases
ATGGCAATTCGCCGTATTGAAGGTTTATTACATCTCGCAAGCGAAGGTCGTTATGCGATTTTAGTGGGTCGTTTCAACAG
TTTTGTTGTTGAACACTTATTAGAAGGCGCGATCGACACGTTAAAACGTCATGGCGTAAATGAAGATAACATTACTGTTA
TTCACGCTCCAGGCGCATGGGAACTACCGATCGTTGCTAAAAAATTAGCTACATCAAACCAGTTTGATGCCATCATTGCA
CTCGGTGCAGTCATTCGTGGTAGCACACCTCACTTTGACTTTGTTGCTGGTGAATGTGCGAAAGGTTTAGGTGTAGTTGC
GTTAGAAAGCAGCTTGCCTGTTATCAATGGTGTATTAACTACTGACAGCATCGAGCAAGCAATCGAACGCTCAGGTACAA
AAGCAGGAAACAAAGGTAGCGAAGCTGCTTTAACTGCAATTGAAATGGTTAATTTATTAAAGGCAATTTAA

Upstream 100 bases:

>100_bases
TGAGCTCACCATTGCGTTTCAATGCCTTATCTGGCTTTAATTTAGAAGTAGTGGAATATGTCACTGCTGATCAAATCACA
ACGAAATAATCGAGGTTGCT

Downstream 100 bases:

>100_bases
AGCATGTCTCAAACACTGCAAGCCGCTTATGCAGCAAAACGTAAAGCACGTCGTTTTGCTGTACAAGGTATTTATGAGTG
GCAAATGAGTCACAACCCTG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MAIRRIEGLLHLASEGRYAILVGRFNSFVVEHLLEGAIDTLKRHGVNEDNITVIHAPGAWELPIVAKKLATSNQFDAIIA
LGAVIRGSTPHFDFVAGECAKGLGVVALESSLPVINGVLTTDSIEQAIERSGTKAGNKGSEAALTAIEMVNLLKAI

Sequences:

>Translated_156_residues
MAIRRIEGLLHLASEGRYAILVGRFNSFVVEHLLEGAIDTLKRHGVNEDNITVIHAPGAWELPIVAKKLATSNQFDAIIA
LGAVIRGSTPHFDFVAGECAKGLGVVALESSLPVINGVLTTDSIEQAIERSGTKAGNKGSEAALTAIEMVNLLKAI
>Mature_155_residues
AIRRIEGLLHLASEGRYAILVGRFNSFVVEHLLEGAIDTLKRHGVNEDNITVIHAPGAWELPIVAKKLATSNQFDAIIAL
GAVIRGSTPHFDFVAGECAKGLGVVALESSLPVINGVLTTDSIEQAIERSGTKAGNKGSEAALTAIEMVNLLKAI

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=143, Percent_Identity=62.2377622377622, Blast_Score=177, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6324429, Length=145, Percent_Identity=31.7241379310345, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16493; Mature: 16362

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRRIEGLLHLASEGRYAILVGRFNSFVVEHLLEGAIDTLKRHGVNEDNITVIHAPGAW
CCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
ELPIVAKKLATSNQFDAIIALGAVIRGSTPHFDFVAGECAKGLGVVALESSLPVINGVLT
CCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHEEC
TDSIEQAIERSGTKAGNKGSEAALTAIEMVNLLKAI
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AIRRIEGLLHLASEGRYAILVGRFNSFVVEHLLEGAIDTLKRHGVNEDNITVIHAPGAW
CHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
ELPIVAKKLATSNQFDAIIALGAVIRGSTPHFDFVAGECAKGLGVVALESSLPVINGVLT
CCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCHHHHEEC
TDSIEQAIERSGTKAGNKGSEAALTAIEMVNLLKAI
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA