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The map label for this gene is ribB [H]

Identifier: 213159128

GI number: 213159128

Start: 3960687

End: 3961808

Strand: Direct

Name: ribB [H]

Synonym: AB57_3838

Alternate gene names: 213159128

Gene position: 3960687-3961808 (Clockwise)

Preceding gene: 213159127

Following gene: 213159129

Centisome position: 97.78

GC content: 44.39

Gene sequence:

>1122_bases
ATGCCGCTGAGTCGTGTTGAAGAACTTGTCGCCGATATTCGTGCAGGCGAAATGGTCATCTTAATGGATGACGAAGACCG
TGAAAATGAAGGTGACCTTGTCATCGCAGCAACGCATGTACGCCCTGAAGATATTAACTTCATGATTACACATGCACGCG
GTTTAGTTTGCTTAACTTTAAGCCGTGAACGTTGTAAACAATTAAACCTCCCACTGATGGTTGACCAGAACGGTGCCCAG
CATGGTACTAACTTTACGTTATCTATCGAAGCAGCTGAAGGTATTACCACAGGTATTTCGGCAGCAGAACGTGCTCACAC
GATTCAAGCTGCTGTGGCAGCACATGCCAAACCAACCGATATTGTACAACCGGGTCATATTTTCCCACTCATGGCACAGC
CAGGTGGTGTATTACACCGTGCAGGTCATACCGAGGCAGGTTGTGATTTAGCACGACTGGCAGGTCTTGAGCCTGCATCT
GTCATTTGTGAAATCATCAAAGAAGATGGCACAATGGCACGCCGCGCAGATTTAGAAATTTTTGCTGAGAAGCATGGCCT
AAAAATTGGTACAATTGCCGACCTAATTCACTACCGTATGACCAATGAGCAAACTGTAGAACGTTTGGATCAAAGAATGA
TTCAAACAGAATATGGTTCATTTGAGCTCTATCGCTATCGTGAGATAGGTAACCCTGACATTCATTTGGCTTTAGTCAAA
GGTGAGCCAAAAGAAGGCGTTACAACGGTACGTGTACATGGTTTTAGTCCTGTTCGCGATTTGCTTAAGCTAAATAAAGC
TGACGGTGAACCGGCTTGGAATCTAGACCGTGCGCTACAAACGATTGCAGCAAGTGACCGCGGCGTTTTAGTCTGGATCG
GACAAGATCATTTGCAAGACTTGGGACCAGCGTTGGATGATTTAACTAAGCCAAAACCGGTGAAATCCAATGCAGCACTT
TCACATCAATATCAAACCATTGGTGTTGGTGCTCAAATTTTGCGTGATTTAGGTGTTGAAAAAATGAAGCTTCTGAGCTC
ACCATTGCGTTTCAATGCCTTATCTGGCTTTAATTTAGAAGTAGTGGAATATGTCACTGCTGATCAAATCACAACGAAAT
AA

Upstream 100 bases:

>100_bases
TTTGGATAAATCAGAATCATAGGCAAAATTCTATAAACAGCGTAAACTATGCGAAATTTATTCAATAGAAATTGTCTTAC
GACAAAAAAGGTGAAAGCGA

Downstream 100 bases:

>100_bases
TCGAGGTTGCTATGGCAATTCGCCGTATTGAAGGTTTATTACATCTCGCAAGCGAAGGTCGTTATGCGATTTTAGTGGGT
CGTTTCAACAGTTTTGTTGT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MPLSRVEELVADIRAGEMVILMDDEDRENEGDLVIAATHVRPEDINFMITHARGLVCLTLSRERCKQLNLPLMVDQNGAQ
HGTNFTLSIEAAEGITTGISAAERAHTIQAAVAAHAKPTDIVQPGHIFPLMAQPGGVLHRAGHTEAGCDLARLAGLEPAS
VICEIIKEDGTMARRADLEIFAEKHGLKIGTIADLIHYRMTNEQTVERLDQRMIQTEYGSFELYRYREIGNPDIHLALVK
GEPKEGVTTVRVHGFSPVRDLLKLNKADGEPAWNLDRALQTIAASDRGVLVWIGQDHLQDLGPALDDLTKPKPVKSNAAL
SHQYQTIGVGAQILRDLGVEKMKLLSSPLRFNALSGFNLEVVEYVTADQITTK

Sequences:

>Translated_373_residues
MPLSRVEELVADIRAGEMVILMDDEDRENEGDLVIAATHVRPEDINFMITHARGLVCLTLSRERCKQLNLPLMVDQNGAQ
HGTNFTLSIEAAEGITTGISAAERAHTIQAAVAAHAKPTDIVQPGHIFPLMAQPGGVLHRAGHTEAGCDLARLAGLEPAS
VICEIIKEDGTMARRADLEIFAEKHGLKIGTIADLIHYRMTNEQTVERLDQRMIQTEYGSFELYRYREIGNPDIHLALVK
GEPKEGVTTVRVHGFSPVRDLLKLNKADGEPAWNLDRALQTIAASDRGVLVWIGQDHLQDLGPALDDLTKPKPVKSNAAL
SHQYQTIGVGAQILRDLGVEKMKLLSSPLRFNALSGFNLEVVEYVTADQITTK
>Mature_372_residues
PLSRVEELVADIRAGEMVILMDDEDRENEGDLVIAATHVRPEDINFMITHARGLVCLTLSRERCKQLNLPLMVDQNGAQH
GTNFTLSIEAAEGITTGISAAERAHTIQAAVAAHAKPTDIVQPGHIFPLMAQPGGVLHRAGHTEAGCDLARLAGLEPASV
ICEIIKEDGTMARRADLEIFAEKHGLKIGTIADLIHYRMTNEQTVERLDQRMIQTEYGSFELYRYREIGNPDIHLALVKG
EPKEGVTTVRVHGFSPVRDLLKLNKADGEPAWNLDRALQTIAASDRGVLVWIGQDHLQDLGPALDDLTKPKPVKSNAALS
HQYQTIGVGAQILRDLGVEKMKLLSSPLRFNALSGFNLEVVEYVTADQITTK

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=203, Percent_Identity=51.7241379310345, Blast_Score=222, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6320695, Length=204, Percent_Identity=39.7058823529412, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40930; Mature: 40799

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSRVEELVADIRAGEMVILMDDEDRENEGDLVIAATHVRPEDINFMITHARGLVCLTL
CCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEE
SRERCKQLNLPLMVDQNGAQHGTNFTLSIEAAEGITTGISAAERAHTIQAAVAAHAKPTD
CHHHHHHCCCCEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
IVQPGHIFPLMAQPGGVLHRAGHTEAGCDLARLAGLEPASVICEIIKEDGTMARRADLEI
CCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCEEHHCCHHE
FAEKHGLKIGTIADLIHYRMTNEQTVERLDQRMIQTEYGSFELYRYREIGNPDIHLALVK
EHHHCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEE
GEPKEGVTTVRVHGFSPVRDLLKLNKADGEPAWNLDRALQTIAASDRGVLVWIGQDHLQD
CCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHH
LGPALDDLTKPKPVKSNAALSHQYQTIGVGAQILRDLGVEKMKLLSSPLRFNALSGFNLE
HCHHHHHHCCCCCCCCCCHHHCCEEEECHHHHHHHHCCHHHHHHHCCCCCEEECCCCCEE
VVEYVTADQITTK
EEEEEECCCCCCC
>Mature Secondary Structure 
PLSRVEELVADIRAGEMVILMDDEDRENEGDLVIAATHVRPEDINFMITHARGLVCLTL
CHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEEEE
SRERCKQLNLPLMVDQNGAQHGTNFTLSIEAAEGITTGISAAERAHTIQAAVAAHAKPTD
CHHHHHHCCCCEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
IVQPGHIFPLMAQPGGVLHRAGHTEAGCDLARLAGLEPASVICEIIKEDGTMARRADLEI
CCCCCCEEEEECCCCCEEEECCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCEEHHCCHHE
FAEKHGLKIGTIADLIHYRMTNEQTVERLDQRMIQTEYGSFELYRYREIGNPDIHLALVK
EHHHCCCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEEE
GEPKEGVTTVRVHGFSPVRDLLKLNKADGEPAWNLDRALQTIAASDRGVLVWIGQDHLQD
CCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHH
LGPALDDLTKPKPVKSNAALSHQYQTIGVGAQILRDLGVEKMKLLSSPLRFNALSGFNLE
HCHHHHHHCCCCCCCCCCHHHCCEEEECHHHHHHHHCCHHHHHHHCCCCCEEECCCCCEE
VVEYVTADQITTK
EEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]