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The map label for this gene is serB [C]

Identifier: 213159126

GI number: 213159126

Start: 3957855

End: 3958991

Strand: Reverse

Name: serB [C]

Synonym: AB57_3836

Alternate gene names: 213159126

Gene position: 3958991-3957855 (Counterclockwise)

Preceding gene: 213159135

Following gene: 213159125

Centisome position: 97.74

GC content: 44.77

Gene sequence:

>1137_bases
TTGCAAATACTGGATGTAGGTCAGGCTGTTATTCATAATCAACTGACATTGGGCATTGTGGTCGCCTCTGAAAATGAAAC
TGCGACCGCGTTGGCAATGAAAGAGATTTTGATTTTAGCACATGATATTGGCTTAACAGTGCGCTTTAAACCTATCTCGG
GCGCAGAATACGATCAATGGGTCAGCGAAGGTGGACGAACTCGTTATATCGTCACGGCTTTAGCACCGGAACTCACTGCT
GCACATTTACAAGCCGTTACACAAATTGTGTCTAGCCAAGGCTTTAACATCGAAACGGTAACTCGTTTATCTGGCCGTGT
AGATCTTGAAAAAGATAGCACATTGCCTCGCCGTGCTTGTGTACAGTTTGGTTTAAGCAGTGGTCCGACTTTAGATGCTC
AAGCTATGCGTGCAGCTTGTTTGCTTCTTTCAAGCGAATTGAATATTGATGTAGCTGTTCAGGAAGATAACGCTTATCGA
CGTAACCGCCGTTTAGTCTGCTTCGATATGGATTCAACTTTAATTGAACAAGAAGTGATTGATGAATTGGCGCTTGAAGC
AGGGGTAGGCGAGCAAGTTGCTGAAATCACTGAAAGAGCGATGCAAGGTGAGTTGGACTTCCAGCAAAGTTTCCGTGCGC
GGGTCGCTTTACTCAAAGGTCTTGATGCGTCAGTTTTACCTAAAATTGCCGAGCGATTGACGATCACCGAAGGTGCCGAG
CGCCTCATTTCGACTTTAAAAGCACTGGGATATAAAACGGCAATTTTATCTGGTGGCTTCCAATATTTTGCTGAATATTT
ACAAGCTAAATTAGGCATTGATGAAGTTCACGCTAACGTTTTAGATGTACAAGATGGCGTTGTGACTGGTGAAGTAAAAG
GTGTAATTGTTGATGGTGCCCGTAAAGCGGAGTTGCTGCGTGAGCTGGCGAACAAACTCGGTATTTCACTAGAGCAAGCG
ATGGCTGTTGGCGATGGCGCAAATGATTTACCGATGCTTGCGATTGCAGGACTTGGCGTAGCATATCGTGCTAAACCACT
GGTGCGTCAAAATGCAAATCAGGCGATTTCAAGCGTTGGTTTGGATGGAGTACTGTATTTACTCGGTATGCATGACAAAG
ATTTAAGCCGTGCTTAA

Upstream 100 bases:

>100_bases
CTAGAGTCAATTCATGCGAGAAATCATTCTTATATCCTTTTTAGGACCGGACCAACCAAACCAGTTTACCCGATTAATGC
AAGTACTATCCGTACATTCA

Downstream 100 bases:

>100_bases
ATAATAGTGAATAATCATTAAGCGCTGCTCAAGAGTAGCGCTTTTTTTATGCAGAATAGTCATAAAAACAAGCAAGTTAT
GACAAAATTATGCACAGAAA

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MQILDVGQAVIHNQLTLGIVVASENETATALAMKEILILAHDIGLTVRFKPISGAEYDQWVSEGGRTRYIVTALAPELTA
AHLQAVTQIVSSQGFNIETVTRLSGRVDLEKDSTLPRRACVQFGLSSGPTLDAQAMRAACLLLSSELNIDVAVQEDNAYR
RNRRLVCFDMDSTLIEQEVIDELALEAGVGEQVAEITERAMQGELDFQQSFRARVALLKGLDASVLPKIAERLTITEGAE
RLISTLKALGYKTAILSGGFQYFAEYLQAKLGIDEVHANVLDVQDGVVTGEVKGVIVDGARKAELLRELANKLGISLEQA
MAVGDGANDLPMLAIAGLGVAYRAKPLVRQNANQAISSVGLDGVLYLLGMHDKDLSRA

Sequences:

>Translated_378_residues
MQILDVGQAVIHNQLTLGIVVASENETATALAMKEILILAHDIGLTVRFKPISGAEYDQWVSEGGRTRYIVTALAPELTA
AHLQAVTQIVSSQGFNIETVTRLSGRVDLEKDSTLPRRACVQFGLSSGPTLDAQAMRAACLLLSSELNIDVAVQEDNAYR
RNRRLVCFDMDSTLIEQEVIDELALEAGVGEQVAEITERAMQGELDFQQSFRARVALLKGLDASVLPKIAERLTITEGAE
RLISTLKALGYKTAILSGGFQYFAEYLQAKLGIDEVHANVLDVQDGVVTGEVKGVIVDGARKAELLRELANKLGISLEQA
MAVGDGANDLPMLAIAGLGVAYRAKPLVRQNANQAISSVGLDGVLYLLGMHDKDLSRA
>Mature_378_residues
MQILDVGQAVIHNQLTLGIVVASENETATALAMKEILILAHDIGLTVRFKPISGAEYDQWVSEGGRTRYIVTALAPELTA
AHLQAVTQIVSSQGFNIETVTRLSGRVDLEKDSTLPRRACVQFGLSSGPTLDAQAMRAACLLLSSELNIDVAVQEDNAYR
RNRRLVCFDMDSTLIEQEVIDELALEAGVGEQVAEITERAMQGELDFQQSFRARVALLKGLDASVLPKIAERLTITEGAE
RLISTLKALGYKTAILSGGFQYFAEYLQAKLGIDEVHANVLDVQDGVVTGEVKGVIVDGARKAELLRELANKLGISLEQA
MAVGDGANDLPMLAIAGLGVAYRAKPLVRQNANQAISSVGLDGVLYLLGMHDKDLSRA

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=186, Percent_Identity=33.8709677419355, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1790849, Length=239, Percent_Identity=49.3723849372385, Blast_Score=206, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI115534456, Length=190, Percent_Identity=32.1052631578947, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534454, Length=190, Percent_Identity=32.1052631578947, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115534458, Length=192, Percent_Identity=31.7708333333333, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6321647, Length=236, Percent_Identity=45.7627118644068, Blast_Score=202, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24661601, Length=188, Percent_Identity=31.3829787234043, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 40711; Mature: 40711

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQILDVGQAVIHNQLTLGIVVASENETATALAMKEILILAHDIGLTVRFKPISGAEYDQW
CCCHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
VSEGGRTRYIVTALAPELTAAHLQAVTQIVSSQGFNIETVTRLSGRVDLEKDSTLPRRAC
HHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCHHHHH
VQFGLSSGPTLDAQAMRAACLLLSSELNIDVAVQEDNAYRRNRRLVCFDMDSTLIEQEVI
HHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHCCEEEEEECCHHHHHHHHH
DELALEAGVGEQVAEITERAMQGELDFQQSFRARVALLKGLDASVLPKIAERLTITEGAE
HHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RLISTLKALGYKTAILSGGFQYFAEYLQAKLGIDEVHANVLDVQDGVVTGEVKGVIVDGA
HHHHHHHHHCHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHEECCCCEEEECCCEEEECCH
RKAELLRELANKLGISLEQAMAVGDGANDLPMLAIAGLGVAYRAKPLVRQNANQAISSVG
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHCCHHHHCCHHHHCCHHHHHHHCC
LDGVLYLLGMHDKDLSRA
CCHHHHEEECCCHHCCCC
>Mature Secondary Structure
MQILDVGQAVIHNQLTLGIVVASENETATALAMKEILILAHDIGLTVRFKPISGAEYDQW
CCCHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
VSEGGRTRYIVTALAPELTAAHLQAVTQIVSSQGFNIETVTRLSGRVDLEKDSTLPRRAC
HHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCHHHHH
VQFGLSSGPTLDAQAMRAACLLLSSELNIDVAVQEDNAYRRNRRLVCFDMDSTLIEQEVI
HHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHCCEEEEEECCHHHHHHHHH
DELALEAGVGEQVAEITERAMQGELDFQQSFRARVALLKGLDASVLPKIAERLTITEGAE
HHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RLISTLKALGYKTAILSGGFQYFAEYLQAKLGIDEVHANVLDVQDGVVTGEVKGVIVDGA
HHHHHHHHHCHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHEECCCCEEEECCCEEEECCH
RKAELLRELANKLGISLEQAMAVGDGANDLPMLAIAGLGVAYRAKPLVRQNANQAISSVG
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHCCHHHHCCHHHHCCHHHHHHHCC
LDGVLYLLGMHDKDLSRA
CCHHHHEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]