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The map label for this gene is dtd

Identifier: 213159123

GI number: 213159123

Start: 3955894

End: 3956337

Strand: Direct

Name: dtd

Synonym: AB57_3833

Alternate gene names: 213159123

Gene position: 3955894-3956337 (Clockwise)

Preceding gene: 213159118

Following gene: 213159127

Centisome position: 97.66

GC content: 42.79

Gene sequence:

>444_bases
ATGCGCGCTTTAATACAACGAGTTCTTGAAGCTAAAGTAGTAGTAGACGGTGAAACGACCGGTGAAATCCAGCATGGCTT
ATTGGTTTTTTTAGGGATCGGTCGAGAAGACACGCTCGCCACCGGACAAAAGCTCATCGACAAGATTTTGAAATATCGTA
TTTTTGATGATGAGCAAGGCAAAATGGGCTGGAATGTATCTCAGGCGAATGGCGGAATCCTGCTTGTTTCACAGTTCACT
TTAATGGCTCAAACGCAAAAAGGACTACGTCCAGACTTTGGTCCGGCCATGCCACCTAGCGACGCAAAAGCACTATATGA
ACAGTTGGTAGAATATACTCGTTCACAGTTTGAAAATGTTCAAACAGGTGTTTTTGCTGCGGACATGAAAGTTCATTTGA
TTAATGATGGACCAGTCACTTTCAATTTAGAAGTTGAAGCATAG

Upstream 100 bases:

>100_bases
ACCATTGTTGCAGTTCCATGAAATTTCCTTTTAAAAATCATTTAATTTAATTTCTGCTAAACTGCATCCATTCAATTAAT
TGCAGAAACTTTCTCTAACA

Downstream 100 bases:

>100_bases
ATATAAAAAAACTCCCGAACGGGAGTTTTTTGTTAGATCTTAACGACCAGTTTTTTCTTTAATAAAAGCACGTGCTTGAC
GTACTTTATCTTTTACTGGT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MRALIQRVLEAKVVVDGETTGEIQHGLLVFLGIGREDTLATGQKLIDKILKYRIFDDEQGKMGWNVSQANGGILLVSQFT
LMAQTQKGLRPDFGPAMPPSDAKALYEQLVEYTRSQFENVQTGVFAADMKVHLINDGPVTFNLEVEA

Sequences:

>Translated_147_residues
MRALIQRVLEAKVVVDGETTGEIQHGLLVFLGIGREDTLATGQKLIDKILKYRIFDDEQGKMGWNVSQANGGILLVSQFT
LMAQTQKGLRPDFGPAMPPSDAKALYEQLVEYTRSQFENVQTGVFAADMKVHLINDGPVTFNLEVEA
>Mature_147_residues
MRALIQRVLEAKVVVDGETTGEIQHGLLVFLGIGREDTLATGQKLIDKILKYRIFDDEQGKMGWNVSQANGGILLVSQFT
LMAQTQKGLRPDFGPAMPPSDAKALYEQLVEYTRSQFENVQTGVFAADMKVHLINDGPVTFNLEVEA

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=151, Percent_Identity=43.7086092715232, Blast_Score=109, Evalue=9e-25,
Organism=Escherichia coli, GI1790320, Length=145, Percent_Identity=55.1724137931034, Blast_Score=162, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI115533292, Length=147, Percent_Identity=38.7755102040816, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=44.5945945945946, Blast_Score=122, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=42.4657534246575, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_ACIB3 (B7GUW9)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002324041.1
- ProteinModelPortal:   B7GUW9
- SMR:   B7GUW9
- GeneID:   7060390
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_000100
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16253; Mature: 16253

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALIQRVLEAKVVVDGETTGEIQHGLLVFLGIGREDTLATGQKLIDKILKYRIFDDEQG
CHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
KMGWNVSQANGGILLVSQFTLMAQTQKGLRPDFGPAMPPSDAKALYEQLVEYTRSQFENV
CCCCEEECCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QTGVFAADMKVHLINDGPVTFNLEVEA
HCCEEEECEEEEEECCCCEEEEEEECC
>Mature Secondary Structure
MRALIQRVLEAKVVVDGETTGEIQHGLLVFLGIGREDTLATGQKLIDKILKYRIFDDEQG
CHHHHHHHHHHEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
KMGWNVSQANGGILLVSQFTLMAQTQKGLRPDFGPAMPPSDAKALYEQLVEYTRSQFENV
CCCCEEECCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QTGVFAADMKVHLINDGPVTFNLEVEA
HCCEEEECEEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA