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The map label for this gene is phoR [H]

Identifier: 213159118

GI number: 213159118

Start: 3949821

End: 3951179

Strand: Direct

Name: phoR [H]

Synonym: AB57_3828

Alternate gene names: 213159118

Gene position: 3949821-3951179 (Clockwise)

Preceding gene: 213159117

Following gene: 213159123

Centisome position: 97.51

GC content: 41.13

Gene sequence:

>1359_bases
ATGTATGAACCCTACCCCGTCCCCGAACAGGTACGTGAACAAAAGCTTTCCCGCTACAGTAGTTTATGGACGTTTGCTAA
ACAAGATTTACGACTTTTATTATTTTTCCTGATTATTGCAGGTTTAGTCGGTTTAGGAATTGGGTATTTCTGGAGCTGTA
TTTTTATTGCCTTTGTGGTGTTTTTTACACTTCAGTTGCGTTCTTTATATTTGGTCAATGACTGGATTGCCAATAATCCA
TACGATGTCCCTCCGAACCTCAACGGAATTTGGGGGGCATTATTATTTAACGTTTACCGTGCCCAGCGCCAAGAACGTAT
TGTTCAAGCGGAAATGGTAGGACTTATTGACCGCGCTCAATCTTCATTAGTTGCACTTGCCGAAGCGGTAGTCTTGATTG
ATGATCAACATCAAATTGAATGGTGGAACCCAGCTGCAGAGCGTTTACTAGGAATTAGTCCACTTGACCGTGGTCGCAAC
TTATTAACCATTTTGCGCCAGCCAACTTTTATTGAATATTTTAACAATATTGATCAGGCACCCGATGGGATTAAACTCCA
TTCGAATTTTGATGATGACCGTTATGTACAGGTTAAGCTCACACGATTTGGTGGGGAAAGTCGCTTACTTGTGGCATACG
ATGTGACTCGTATGCATAATCTTGAGCAAATGCGTAAAGACTTTGTCGATAATATTTCGCATGAACTACGTACACCATTA
ACCGTGCTCAGTGGTTATATCGAAACCTTTACCGACCAAGAAGATATTAACCCGCGCTGGAAACGTGCATTTGACCAGAT
GCAATCTCAAACCAAACGTATGAATGCGTTGGTTAATGATTTACTACTGTTATCAAATTTAGAAAATAATAAGAAAATCG
CAAAAAATCAGATTATTGAAATGCCGAGCTTAATGAATCAATTATTTGATGATGCTCAGGCCTACAATGCCGATTATGGG
CATACACTCAATTTACATATTGATAGCCACTGTGACCTCATCGGTTCTGACATGGAAATTGCCAGCGCATTTAGTAATTT
AATTACCAATGCCATTAAGTACACACCAAAAGGTGGAACCATTACCATTGGCTGGCACGATGACGGTGAGCATGCTTACT
TTAGTGTACAAGATACCGGTATCGGCATTAACCCTAAACATTTGCCGCGTCTGACTGAACGCTTCTATCGTGTGGACAGC
GACCGTAGTCGTCAAACTGGTGGAACTGGTTTAGGCTTGGCGATTGTAAAACACGTACTCATGCAACACGGCGCCTACTT
AGACGTGCAATCTAAAGAAAATGAAGGATCAACCTTTACCGCAGTTTTTCCAAAAGAAAGACTCTATAACATGACCTAA

Upstream 100 bases:

>100_bases
CTTAGAACCTTTTGGTGTAGACCGATTTGTTCAGACTGTACGTGGTACAGGTTATCGTTTCTCAACACGTGCAGATTTAG
CCGCAGGTTAACCAAAATTT

Downstream 100 bases:

>100_bases
AATCATCTTTTTTCAAATATAAAAAGCCGACTCATGAAAAGTCGGCTTTTTTGTAGCATTTAAACCTATTTATTTAAAAT
TTGAACAATAAGATTTCGCC

Product: phosphate regulon sensor kinase PhoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MYEPYPVPEQVREQKLSRYSSLWTFAKQDLRLLLFFLIIAGLVGLGIGYFWSCIFIAFVVFFTLQLRSLYLVNDWIANNP
YDVPPNLNGIWGALLFNVYRAQRQERIVQAEMVGLIDRAQSSLVALAEAVVLIDDQHQIEWWNPAAERLLGISPLDRGRN
LLTILRQPTFIEYFNNIDQAPDGIKLHSNFDDDRYVQVKLTRFGGESRLLVAYDVTRMHNLEQMRKDFVDNISHELRTPL
TVLSGYIETFTDQEDINPRWKRAFDQMQSQTKRMNALVNDLLLLSNLENNKKIAKNQIIEMPSLMNQLFDDAQAYNADYG
HTLNLHIDSHCDLIGSDMEIASAFSNLITNAIKYTPKGGTITIGWHDDGEHAYFSVQDTGIGINPKHLPRLTERFYRVDS
DRSRQTGGTGLGLAIVKHVLMQHGAYLDVQSKENEGSTFTAVFPKERLYNMT

Sequences:

>Translated_452_residues
MYEPYPVPEQVREQKLSRYSSLWTFAKQDLRLLLFFLIIAGLVGLGIGYFWSCIFIAFVVFFTLQLRSLYLVNDWIANNP
YDVPPNLNGIWGALLFNVYRAQRQERIVQAEMVGLIDRAQSSLVALAEAVVLIDDQHQIEWWNPAAERLLGISPLDRGRN
LLTILRQPTFIEYFNNIDQAPDGIKLHSNFDDDRYVQVKLTRFGGESRLLVAYDVTRMHNLEQMRKDFVDNISHELRTPL
TVLSGYIETFTDQEDINPRWKRAFDQMQSQTKRMNALVNDLLLLSNLENNKKIAKNQIIEMPSLMNQLFDDAQAYNADYG
HTLNLHIDSHCDLIGSDMEIASAFSNLITNAIKYTPKGGTITIGWHDDGEHAYFSVQDTGIGINPKHLPRLTERFYRVDS
DRSRQTGGTGLGLAIVKHVLMQHGAYLDVQSKENEGSTFTAVFPKERLYNMT
>Mature_452_residues
MYEPYPVPEQVREQKLSRYSSLWTFAKQDLRLLLFFLIIAGLVGLGIGYFWSCIFIAFVVFFTLQLRSLYLVNDWIANNP
YDVPPNLNGIWGALLFNVYRAQRQERIVQAEMVGLIDRAQSSLVALAEAVVLIDDQHQIEWWNPAAERLLGISPLDRGRN
LLTILRQPTFIEYFNNIDQAPDGIKLHSNFDDDRYVQVKLTRFGGESRLLVAYDVTRMHNLEQMRKDFVDNISHELRTPL
TVLSGYIETFTDQEDINPRWKRAFDQMQSQTKRMNALVNDLLLLSNLENNKKIAKNQIIEMPSLMNQLFDDAQAYNADYG
HTLNLHIDSHCDLIGSDMEIASAFSNLITNAIKYTPKGGTITIGWHDDGEHAYFSVQDTGIGINPKHLPRLTERFYRVDS
DRSRQTGGTGLGLAIVKHVLMQHGAYLDVQSKENEGSTFTAVFPKERLYNMT

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=416, Percent_Identity=36.7788461538462, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=31.304347826087, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=28.7610619469027, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1789149, Length=230, Percent_Identity=30, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1790346, Length=218, Percent_Identity=27.9816513761468, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=28.3185840707965, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI145693157, Length=224, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789403, Length=225, Percent_Identity=29.7777777777778, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787894, Length=333, Percent_Identity=26.1261261261261, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=31.1004784688995, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=26.431718061674, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87081816, Length=229, Percent_Identity=28.3842794759825, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=242, Percent_Identity=26.0330578512397, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=24.4541484716157, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=25.3393665158371, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=341, Percent_Identity=23.1671554252199, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790551, Length=228, Percent_Identity=27.6315789473684, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788279, Length=200, Percent_Identity=26.5, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87082128, Length=219, Percent_Identity=25.5707762557078, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51846; Mature: 51846

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEPYPVPEQVREQKLSRYSSLWTFAKQDLRLLLFFLIIAGLVGLGIGYFWSCIFIAFVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFTLQLRSLYLVNDWIANNPYDVPPNLNGIWGALLFNVYRAQRQERIVQAEMVGLIDRAQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLVALAEAVVLIDDQHQIEWWNPAAERLLGISPLDRGRNLLTILRQPTFIEYFNNIDQA
HHHHHHHHHHHEECCCCCCEECCHHHHHHCCCCCHHCCCHHHHHHCCCHHHHHHHHHCCC
PDGIKLHSNFDDDRYVQVKLTRFGGESRLLVAYDVTRMHNLEQMRKDFVDNISHELRTPL
CCCEEECCCCCCCCEEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCHH
TVLSGYIETFTDQEDINPRWKRAFDQMQSQTKRMNALVNDLLLLSNLENNKKIAKNQIIE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MPSLMNQLFDDAQAYNADYGHTLNLHIDSHCDLIGSDMEIASAFSNLITNAIKYTPKGGT
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCE
ITIGWHDDGEHAYFSVQDTGIGINPKHLPRLTERFYRVDSDRSRQTGGTGLGLAIVKHVL
EEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
MQHGAYLDVQSKENEGSTFTAVFPKERLYNMT
HHCCCEEEEECCCCCCCEEEEECCHHHHCCCC
>Mature Secondary Structure
MYEPYPVPEQVREQKLSRYSSLWTFAKQDLRLLLFFLIIAGLVGLGIGYFWSCIFIAFVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFTLQLRSLYLVNDWIANNPYDVPPNLNGIWGALLFNVYRAQRQERIVQAEMVGLIDRAQ
HHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSLVALAEAVVLIDDQHQIEWWNPAAERLLGISPLDRGRNLLTILRQPTFIEYFNNIDQA
HHHHHHHHHHHEECCCCCCEECCHHHHHHCCCCCHHCCCHHHHHHCCCHHHHHHHHHCCC
PDGIKLHSNFDDDRYVQVKLTRFGGESRLLVAYDVTRMHNLEQMRKDFVDNISHELRTPL
CCCEEECCCCCCCCEEEEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCHH
TVLSGYIETFTDQEDINPRWKRAFDQMQSQTKRMNALVNDLLLLSNLENNKKIAKNQIIE
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MPSLMNQLFDDAQAYNADYGHTLNLHIDSHCDLIGSDMEIASAFSNLITNAIKYTPKGGT
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHEECCCCCE
ITIGWHDDGEHAYFSVQDTGIGINPKHLPRLTERFYRVDSDRSRQTGGTGLGLAIVKHVL
EEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
MQHGAYLDVQSKENEGSTFTAVFPKERLYNMT
HHCCCEEEEECCCCCCCEEEEECCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043; 2115874 [H]